UK guidelines on the management of variceal haemorrhage in cirrhotic patients.

PubWeight™: 1.20‹?› | Rank: Top 10%

🔗 View Article (PMID 25887380)

Published in Gut on April 17, 2015

Authors

Dhiraj Tripathi1, Adrian J Stanley2, Peter C Hayes3, David Patch4, Charles Millson5, Homoyon Mehrzad6, Andrew Austin7, James W Ferguson1, Simon P Olliff6, Mark Hudson8, John M Christie9, Clinical Services and Standards Committee of the British Society of Gastroenterology

Author Affiliations

1: Liver Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
2: GI Unit, Glasgow Royal Infirmary, Glasgow, UK.
3: Liver Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.
4: The Royal Free Sheila Sherlock Liver Centre, Royal Free Hospital and University College London, London, UK.
5: Gastrointestinal and Liver Services, York Teaching Hospitals NHS Foundation Trust, York, UK.
6: Department of Interventional Radiology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
7: Department of Gastroenterology, Derby Hospitals NHS Foundation Trust, Derby, UK.
8: Liver Unit, Freeman Hospital, Newcastle upon Tyne, UK.
9: Department of Gastroenterology, Royal Devon and Exeter Hospital, Devon, UK.

Associated clinical trials:

Timing of Endoscopic Intervention for Acute Variceal Hemorrhage: an RCT (TEACH) | NCT04786743

The Timing of Emergency Endoscopy for Esophagogastric Variceal Bleeding in Cirrhosis | NCT04932200

Articles citing this

Diagnostic Accuracy of APRI, AAR, FIB-4, FI, King, Lok, Forns, and FibroIndex Scores in Predicting the Presence of Esophageal Varices in Liver Cirrhosis: A Systematic Review and Meta-Analysis. Medicine (Baltimore) (2015) 0.90

Acute-on-chronic liver failure: Pathogenesis, prognostic factors and management. World J Gastroenterol (2015) 0.82

Knowledge about non-invasive diagnostic tests for varices in liver cirrhosis: A questionnaire survey to the Gastroenterology Branch of the Liaoning Medical Association, China. Gastroenterol Rep (Oxf) (2015) 0.79

Recent advances in the management of variceal bleeding. Gastroenterol Rep (Oxf) (2017) 0.76

Primary Prophylaxis for Variceal Bleeding and the Improved Survival of Patients with Newly Diagnosed Hepatocellular Carcinoma. Dig Dis Sci (2016) 0.76

Early TIPS in U.S. Patients Hospitalized with Acute Esophageal Variceal Bleeding. J Gastroenterol Hepatol (2016) 0.75

Splenectomy Causes 10-Fold Increased Risk of Portal Venous System Thrombosis in Liver Cirrhosis Patients. Med Sci Monit (2016) 0.75

Spleen Stiffness Is Superior to Liver Stiffness for Predicting Esophageal Varices in Chronic Liver Disease: A Meta-Analysis. PLoS One (2016) 0.75

Non-invasive Diagnosis of Oesophageal Varices Using Systemic Haemodynamic Measurements by Finometry: Comparison with Other Non-invasive Predictive Scores. J Clin Exp Hepatol (2016) 0.75

Covered versus bare stents for transjugular intrahepatic portosystemic shunt: an updated meta-analysis of randomized controlled trials. Therap Adv Gastroenterol (2016) 0.75

Medical expenses in treating acute esophageal variceal bleeding: A 15-year nationwide population-based cohort study. Medicine (Baltimore) (2016) 0.75

Liver - guardian, modifier and target of sepsis. Nat Rev Gastroenterol Hepatol (2016) 0.75

Management before hepatectomy for hepatocellular carcinoma with cirrhosis. World J Hepatol (2015) 0.75

Oesophageal and gastric varices: historical aspects, classification and grading: everything in one place. Gastroenterol Rep (Oxf) (2016) 0.75

Endoscopic Ultrasound-Guided Vascular Therapy: The Present and the Future. Clin Endosc (2017) 0.75

The Role of Adjuvant Acid Suppression on the Outcomes of Bleeding Esophageal Varices after Endoscopic Variceal Ligation. PLoS One (2017) 0.75

Bleeding Risk with Invasive Procedures in Patients with Cirrhosis and Coagulopathy. Curr Gastroenterol Rep (2017) 0.75

Impact of hepatitis C oral therapy in portal hypertension. World J Gastroenterol (2017) 0.75

Therapeutic evaluation of arterio-portal fistula-related gastroesophageal variceal bleeding. Oncotarget (2017) 0.75

Optimal interval times for rescoping after an acute variceal haemorrhage. Frontline Gastroenterol (2015) 0.75

Articles cited by this

(truncated to the top 100)

A model to predict survival in patients with end-stage liver disease. Hepatology (2001) 18.06

Proposed changes for nurse education in England (UK) as a result of the Darzi report (DoH, 2008a) Health Quality Care for All--NHS next stage review final report: some initial observations. Nurse Educ Pract (2008) 14.45

Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med (2013) 10.19

AGREE II: advancing guideline development, reporting and evaluation in health care. CMAJ (2010) 8.73

Early use of TIPS in patients with cirrhosis and variceal bleeding. N Engl J Med (2010) 8.40

Deleterious effects of beta-blockers on survival in patients with cirrhosis and refractory ascites. Hepatology (2010) 8.11

Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. N Engl J Med (2005) 6.31

Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis. Lancet (1995) 6.06

Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatol (2010) 5.78

The coagulopathy of chronic liver disease. N Engl J Med (2011) 5.63

Nonselective β blockers increase risk for hepatorenal syndrome and death in patients with cirrhosis and spontaneous bacterial peritonitis. Gastroenterology (2014) 4.36

Prevalence, classification and natural history of gastric varices: a long-term follow-up study in 568 portal hypertension patients. Hepatology (1992) 4.22

Proton pump inhibitor treatment is associated with the severity of liver disease and increased mortality in patients with cirrhosis. Aliment Pharmacol Ther (2014) 3.91

Clostridium difficile-associated diarrhea and proton pump inhibitor therapy: a meta-analysis. Am J Gastroenterol (2012) 3.59

Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices. A prospective multicenter study. N Engl J Med (1988) 3.53

Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosis. Hepatology (2007) 3.39

The course of patients after variceal hemorrhage. Gastroenterology (1981) 3.33

Randomized controlled trial of carvedilol versus variceal band ligation for the prevention of the first variceal bleed. Hepatology (2009) 3.20

Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators. Hepatology (2003) 3.19

Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores. J Hepatol (2008) 3.12

The treatment of portal hypertension: a meta-analytic review. Hepatology (1995) 3.11

Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage. Gastroenterology (1990) 2.99

Treatment of gastric fundal varices by balloon-occluded retrograde transvenous obliteration. J Gastroenterol Hepatol (1996) 2.81

A prospective, randomized controlled trial of transjugular intrahepatic portosystemic shunt versus cyanoacrylate injection in the prevention of gastric variceal rebleeding. Endoscopy (2007) 2.78

Platelet count/spleen diameter ratio for the noninvasive diagnosis of esophageal varices: results of a multicenter, prospective, validation study. Am J Gastroenterol (2006) 2.64

A prospective, randomized trial of butyl cyanoacrylate injection versus band ligation in the management of bleeding gastric varices. Hepatology (2001) 2.64

Endoscopic cyanoacrylate versus transjugular intrahepatic portosystemic shunt for gastric variceal bleeding: a single-center U.S. analysis. Gastrointest Endosc (2009) 2.63

Prediction of variceal hemorrhage by esophageal endoscopy. Gastrointest Endosc (1981) 2.62

Liver stiffness accurately predicts portal hypertension related complications in patients with chronic liver disease: a prospective study. J Hepatol (2011) 2.61

Endoscopic treatment versus endoscopic plus pharmacologic treatment for acute variceal bleeding: a meta-analysis. Hepatology (2002) 2.49

Incidence and natural history of small esophageal varices in cirrhotic patients. J Hepatol (2003) 2.46

Increased long-term survival in variceal haemorrhage using injection sclerotherapy. Results of a controlled trial. Lancet (1982) 2.30

Non-selective β-blockers are associated with improved survival in patients with ascites listed for liver transplantation. Gut (2014) 2.26

Covered vs. uncovered stents for transjugular intrahepatic portosystemic shunt: a randomized controlled trial. J Hepatol (2014) 2.22

Selection of patients for liver transplantation and allocation of donated livers in the UK. Gut (2007) 2.20

A controlled study of the prophylactic portacaval shunt. A final report. Ann Intern Med (1969) 2.19

Urgent vs. non-urgent endoscopy in stable acute variceal bleeding. Am J Gastroenterol (2009) 2.17

Pharmacological treatment of portal hypertension: an evidence-based approach. Semin Liver Dis (1999) 2.15

Lack of difference among terlipressin, somatostatin, and octreotide in the control of acute gastroesophageal variceal hemorrhage. Hepatology (2014) 2.14

Pharmacotherapy plus endoscopic intervention is more effective than pharmacotherapy or endoscopy alone in the secondary prevention of esophageal variceal bleeding: a meta-analysis of randomized, controlled trials. Gastrointest Endosc (2009) 2.10

Portal pressure, presence of gastroesophageal varices and variceal bleeding. Hepatology (1985) 2.09

Meta-analysis: Combination endoscopic and drug therapy to prevent variceal rebleeding in cirrhosis. Ann Intern Med (2008) 2.05

Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis. Ann Intern Med (1995) 2.04

Portal hypertension, size of esophageal varices, and risk of gastrointestinal bleeding in alcoholic cirrhosis. Gastroenterology (1980) 2.02

The role of the transjugular intrahepatic portosystemic stent shunt (TIPSS) in the management of bleeding gastric varices: clinical and haemodynamic correlations. Gut (2002) 2.00

Endoscopic injection sclerosis in bleeding gastric varices. Gastrointest Endosc (1986) 1.99

Prophylactic portacaval anastomosis. Medicine (Baltimore) (1972) 1.99

Endoscopic therapy with 2-octyl-cyanoacrylate for the treatment of gastric varices. Dig Dis Sci (2014) 1.99

Comparison of scoring systems and outcome of patients admitted to a liver intensive care unit of a tertiary referral centre with severe variceal bleeding. Aliment Pharmacol Ther (2014) 1.98

Improved survival in patients receiving medical therapy as compared with banding ligation for the prevention of esophageal variceal rebleeding. Hepatology (2008) 1.95

"Salvage" transjugular intrahepatic portosystemic shunts: gastric fundal compared with esophageal variceal bleeding. Gastroenterology (1998) 1.95

Esophageal capsule endoscopy for screening and surveillance of esophageal varices in patients with portal hypertension. Hepatology (2008) 1.91

A randomized, controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis. Gastroenterology (2002) 1.90

Carvedilol for primary prophylaxis of variceal bleeding in cirrhotic patients with haemodynamic non-response to propranolol. Gut (2012) 1.83

Distal splenorenal shunt versus transjugular intrahepatic portal systematic shunt for variceal bleeding: a randomized trial. Gastroenterology (2006) 1.82

EUS-guided coil versus cyanoacrylate therapy for the treatment of gastric varices: a multicenter study (with videos). Gastrointest Endosc (2013) 1.81

A MELD-based model to determine risk of mortality among patients with acute variceal bleeding. Gastroenterology (2013) 1.77

Transjugular intrahepatic portosystemic shunt versus endoscopic therapy in the secondary prophylaxis of variceal rebleeding in cirrhotic patients: meta-analysis update. J Clin Gastroenterol (2008) 1.74

A clinical investigation of the portacaval shunt. II. Survival analysis of the prophylactic operation. Am J Surg (1968) 1.72

Nitroglycerin improves the hemodynamic response to vasopressin in portal hypertension. Hepatology (1983) 1.67

Platelet count/spleen diameter ratio to predict the presence of esophageal varices in patients with cirrhosis: a systematic review. Eur J Gastroenterol Hepatol (2012) 1.67

Patency of stents covered with polytetrafluoroethylene in patients treated by transjugular intrahepatic portosystemic shunts: long-term results of a randomized multicentre study. Liver Int (2007) 1.66

Primary prophylaxis of gastric variceal bleeding comparing cyanoacrylate injection and beta-blockers: a randomized controlled trial. J Hepatol (2010) 1.66

The use of thrombin injections in the management of bleeding gastric varices: a single-center experience. Gastrointest Endosc (2008) 1.65

Esophageal capsule endoscopy vs. EGD for the evaluation of portal hypertension: a French prospective multicenter comparative study. Am J Gastroenterol (2009) 1.65

Double-blind randomized controlled trial comparing terlipressin and somatostatin for acute variceal hemorrhage. Variceal Bleeding Study Group. Gastroenterology (1996) 1.64

Balloon-occluded retrograde transvenous obliteration for gastric varices with gastrorenal or gastrocaval collaterals. AJR Am J Roentgenol (1996) 1.63

Meta-analysis: antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding - an updated Cochrane review. Aliment Pharmacol Ther (2011) 1.62

Hepatic venous pressure gradient and prognosis in patients with acute variceal bleeding treated with pharmacologic and endoscopic therapy. J Hepatol (2007) 1.60

Cost of preventing variceal rebleeding with transjugular intrahepatic portal systemic shunt and distal splenorenal shunt. J Hepatol (2007) 1.59

Minimally invasive measurement of esophageal variceal pressure and wall tension (with video). Gastrointest Endosc (2009) 1.59

Randomized, controlled trial of carvedilol versus nadolol plus isosorbide mononitrate for the prevention of variceal rebleeding. J Gastroenterol Hepatol (2012) 1.58

EUS-guided injection of cyanoacrylate for bleeding gastric varices. Gastrointest Endosc (2000) 1.57

A randomized trial of endoscopic treatment of acute gastric variceal hemorrhage: N-butyl-2-cyanoacrylate injection versus band ligation. Hepatology (2006) 1.57

Prognostic value of acute hemodynamic response to i.v. propranolol in patients with cirrhosis and portal hypertension. J Hepatol (2009) 1.57

Predictors of early re-bleeding and mortality after acute variceal haemorrhage in patients with cirrhosis. Gut (2008) 1.56

Systematic review: secondary prevention with band ligation, pharmacotherapy or combination therapy after bleeding from oesophageal varices. Aliment Pharmacol Ther (2009) 1.56

PROPHYLACTIC PORTACAVAL ANASTOMOSIS IN CIRRHOTIC PATIENTS WITH ESOPHAGEAL VARICES: A PROGRESS REPORT OF A CONTINUING STUDY. N Engl J Med (1965) 1.55

Ethanolamine oleate versus butyl cyanoacrylate for bleeding gastric varices: a nonrandomized study. Endoscopy (1995) 1.55

Influence of portal hypertension and its early decompression by TIPS placement on the outcome of variceal bleeding. Hepatology (2004) 1.55

Propranolol plus placebo versus propranolol plus isosorbide-5-mononitrate in the prevention of a first variceal bleed: a double-blind RCT. Hepatology (2003) 1.54

Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage. Gastroenterology (2006) 1.54

The natural history of esophageal varices; a study of 115 cirrhotic patients in whom varices were diagnosed prior to bleeding. Am J Med (1959) 1.53

Cost-effectiveness of N-butyl-2-cyanoacrylate (histoacryl) glue injections versus transjugular intrahepatic portosystemic shunt in the management of acute gastric variceal bleeding. Am J Gastroenterol (2003) 1.50

Acute variceal haemorrhage in the United Kingdom: patient characteristics, management and outcomes in a nationwide audit. Dig Liver Dis (2014) 1.49

A randomized controlled trial comparing ligation and sclerotherapy as emergency endoscopic treatment added to somatostatin in acute variceal bleeding. J Hepatol (2006) 1.48

A placebo-controlled clinical trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosis. Gastroenterology (2004) 1.47

Randomized controlled trial of emergency transjugular intrahepatic portosystemic shunt versus emergency portacaval shunt treatment of acute bleeding esophageal varices in cirrhosis. J Gastrointest Surg (2012) 1.45

TIPS for prevention of recurrent bleeding in patients with cirrhosis: meta-analysis of randomized clinical trials. Radiology (1999) 1.42

Efficacy of balloon tamponade in treatment of bleeding gastric and esophageal varices. Results in 151 consecutive episodes. Dig Dis Sci (1988) 1.40

Balloon-occluded retrograde transvenous obliteration for gastric variceal bleeding: its feasibility compared with transjugular intrahepatic portosystemic shunt. Korean J Radiol (2003) 1.38

A self-expanding metal stent for complicated variceal hemorrhage: experience at a single center. Gastrointest Endosc (2009) 1.35

Propranolol in the prevention of first upper gastrointestinal tract hemorrhage in patients with cirrhosis of the liver and esophageal varices. N Engl J Med (1987) 1.34

N-butyl-2-cyanoacrylate: a supplement to endoscopic sclerotherapy. Endoscopy (1987) 1.31

Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis. Hepatology (2002) 1.30

Transjugular intrahepatic portosystemic shunt compared with endoscopic treatment for prevention of variceal rebleeding: A meta-analysis. Hepatology (1999) 1.29

Transjugular intrahepatic portosystemic shunts for patients with active variceal hemorrhage unresponsive to sclerotherapy. Gastroenterology (1996) 1.28

Balloon-occluded retrograde transvenous obliteration of gastric varices: outcomes and complications in 49 patients. AJR Am J Roentgenol (2007) 1.26

Aspects of the natural history of gastrointestinal bleeding in cirrhosis and the effect of prednisone. Gastroenterology (1981) 1.25

Effects of somatostatin on hepatic and systemic hemodynamics in patients with cirrhosis of the liver: comparison with vasopressin. Gastroenterology (1981) 1.25