Quantitative assessment of antibody internalization with novel monoclonal antibodies against Alexa fluorophores.

Correction: Quantitative Assessment of Antibody Internalization with Novel Monoclonal Antibodies against Alexa Fluorophores. PLoS One (2015) 1.07

A novel antibody-drug conjugate targeting SAIL for the treatment of hematologic malignancies. Blood Cancer J (2015) 0.79

Correction: Quantitative Assessment of Antibody Internalization with Novel Monoclonal Antibodies against Alexa Fluorophores. PLoS One (2015) 0.75

NIH Image to ImageJ: 25 years of image analysis. Nat Methods (2012) 84.41

Systems survey of endocytosis by multiparametric image analysis. Nature (2010) 5.03

Alexa dyes, a series of new fluorescent dyes that yield exceptionally bright, photostable conjugates. J Histochem Cytochem (1999) 4.71

Viral reorganization of the secretory pathway generates distinct organelles for RNA replication. Cell (2010) 4.47

Antibody targeted drugs as cancer therapeutics. Nat Rev Drug Discov (2006) 3.08

Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization. J Exp Med (2004) 2.86

The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells. Cancer Res (2004) 2.64

Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin. Mol Biol Cell (2004) 2.60

Human and mouse granzyme A induce a proinflammatory cytokine response. Immunity (2008) 2.57

SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML. Blood (2013) 2.26

Structural and quantitative analysis of astrocytes in the mouse hippocampus. Neuroscience (2002) 1.95

Dual targeting of HER2-positive cancer with trastuzumab emtansine and pertuzumab: critical role for neuregulin blockade in antitumor response to combination therapy. Clin Cancer Res (2013) 1.89

A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester. J Immunol Methods (2009) 1.78

WNK1 kinase isoform switch regulates renal potassium excretion. Proc Natl Acad Sci U S A (2006) 1.65

Influence of affinity and antigen internalization on the uptake and penetration of Anti-HER2 antibodies in solid tumors. Cancer Res (2011) 1.62

Treatment of hematologic malignancies with immunotoxins and antibody-drug conjugates. Cancer Res (2011) 1.54

GLUT4 is internalized by a cholesterol-dependent nystatin-sensitive mechanism inhibited by insulin. EMBO J (2006) 1.42

Three types of neurochemical projection from the bed nucleus of the stria terminalis to the ventral tegmental area in adult mice. J Neurosci (2012) 1.38

Mechanisms of quenching of Alexa fluorophores by natural amino acids. J Am Chem Soc (2010) 1.31

A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo. Cancer Res (2008) 1.25

Rapid development of affinity matured monoclonal antibodies using RIMMS. Hybridoma (1997) 1.15

Requirements for the internalization of a murine monoclonal antibody directed against the HER-2/neu gene product c-erbB-2. Cancer Res (1991) 1.15

Axon initial segment cytoskeleton comprises a multiprotein submembranous coat containing sparse actin filaments. J Cell Biol (2014) 1.13

Discovery of fully human anti-MET monoclonal antibodies with antitumor activity against colon cancer tumor models in vivo. Neoplasia (2009) 1.10

Tracking viral genomes in host cells at single-molecule resolution. Cell Host Microbe (2013) 1.05

Antibody-drug conjugates: an emerging modality for the treatment of cancer. Ann N Y Acad Sci (2014) 1.04

High CD21 expression inhibits internalization of anti-CD19 antibodies and cytotoxicity of an anti-CD19-drug conjugate. Br J Haematol (2007) 1.03

Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index. Mol Cancer Ther (2008) 0.99

Assessing the sensitivity of commercially available fluorophores to the intracellular environment. Anal Chem (2008) 0.96

Use of anti-fluorophore antibody to achieve high-sensitivity immunolocalizations of transporters and ion channels. J Histochem Cytochem (2006) 0.94

Novel flow cytometric analysis of the progress and route of internalization of a monoclonal anti-carcinoembryonic antigen (CEA) antibody. Cytometry (1996) 0.91

Therapeutic antibody targeting of CD97 in experimental arthritis: the role of antigen expression, shedding, and internalization on the pharmacokinetics of anti-CD97 monoclonal antibody 1B2. J Immunol (2009) 0.84

Structural and functional characterization of an agonistic anti-human EphA2 monoclonal antibody. J Mol Biol (2011) 0.84

Targeted delivery of immunotoxin by antibody to ganglioside GD3: a novel drug delivery route for tumor cells. PLoS One (2013) 0.82

Monoclonal antibody binding-site diversity assessment with a cell-based clustering assay. J Immunol Methods (2013) 0.82