Published in Nat Rev Mol Cell Biol on May 01, 2015
Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis. Cell Stem Cell (2016) 1.54
Dormant Intestinal Stem Cells Are Regulated by PTEN and Nutritional Status. Cell Rep (2015) 1.51
Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping. Nat Protoc (2015) 1.25
A decade of transcription factor-mediated reprogramming to pluripotency. Nat Rev Mol Cell Biol (2016) 1.16
Hardwiring Stem Cell Communication through Tissue Structure. Cell (2016) 0.97
Ovary and fimbrial stem cells: biology, niche and cancer origins. Nat Rev Mol Cell Biol (2015) 0.86
Extracting structural and functional features of widely distributed biological circuits with single cell resolution via tissue clearing and delivery vectors. Curr Opin Biotechnol (2016) 0.86
Adult cell plasticity in vivo: de-differentiation and transdifferentiation are back in style. Nat Rev Mol Cell Biol (2016) 0.81
Advances in bone marrow stem cell therapy for retinal dysfunction. Prog Retin Eye Res (2016) 0.79
Stem-like features of cancer cells on their way to metastasis. Biol Direct (2016) 0.78
Bone Marrow-Derived Cells as a Therapeutic Approach to Optic Nerve Diseases. Stem Cells Int (2015) 0.78
Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues. J Physiol (2016) 0.77
Ovine Hair Follicle Stem Cells Derived from Single Vibrissae Reconstitute Haired Skin. Int J Mol Sci (2015) 0.76
Rejuvenating stem cells to restore muscle regeneration in aging. F1000Res (2017) 0.75
Equine-Induced Pluripotent Stem Cells Retain Lineage Commitment Toward Myogenic and Chondrogenic Fates. Stem Cell Reports (2016) 0.75
Tissue-Specific Cultured Human Pericytes: Perivascular Cells from Smooth Muscle Tissue Have Restricted Mesodermal Differentiation Ability. Stem Cells Dev (2016) 0.75
An enduring role for quiescent stem cells. Dev Dyn (2016) 0.75
Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice. Stem Cell Reports (2017) 0.75
Single-Cell Transcriptomic Analysis Defines Heterogeneity and Transcriptional Dynamics in the Adult Neural Stem Cell Lineage. Cell Rep (2017) 0.75
The Hippo pathway in tissue homeostasis and regeneration. Protein Cell (2017) 0.75
Identifying Quiescent Stem Cells in Hair Follicles. Methods Mol Biol (2018) 0.75
CD44-high alveolar type II cells show stem cell properties during steady-state alveolar homeostasis. Am J Physiol Lung Cell Mol Physiol (2017) 0.75
A revisionist history of adult marrow stem cell biology or 'They forgot about the discard'. Leukemia (2017) 0.75
Quantitative Systems Biology to decipher design principles of a dynamic cell cycle network: the "Maximum Allowable mammalian Trade-Off-Weight" (MAmTOW). NPJ Syst Biol Appl (2017) 0.75
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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature (2009) 19.18
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Defining the epithelial stem cell niche in skin. Science (2003) 14.93
Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science (1996) 12.54
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Cell (2010) 12.23
Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell (1990) 12.13
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature (2006) 11.90
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell (2004) 10.79
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Nature (2010) 10.60
Capturing and profiling adult hair follicle stem cells. Nat Biotechnol (2004) 10.35
Bmi1 is expressed in vivo in intestinal stem cells. Nat Genet (2008) 10.22
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development (1999) 9.82
The origin and evolution of mutations in acute myeloid leukemia. Cell (2012) 9.66
Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell (2005) 8.37
Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types. Am J Anat (1974) 8.05
Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med (2005) 8.01
Lgr5 marks cycling, yet long-lived, hair follicle stem cells. Nat Genet (2008) 7.55
Coexistence of quiescent and active adult stem cells in mammals. Science (2010) 7.54
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat Genet (2004) 7.37
Transcription factor achaete scute-like 2 controls intestinal stem cell fate. Cell (2009) 7.08
Involvement of follicular stem cells in forming not only the follicle but also the epidermis. Cell (2000) 6.93
Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia. Nature (2014) 6.83
Endothelial and perivascular cells maintain haematopoietic stem cells. Nature (2012) 6.60
Distinct stem cells contribute to mammary gland development and maintenance. Nature (2011) 6.32
A single type of progenitor cell maintains normal epidermis. Nature (2007) 6.32
A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages. J Invest Dermatol (2001) 6.12
Developmental potential and dynamic behavior of hematopoietic stem cells. Cell (1986) 5.98
The increasing complexity of the cancer stem cell paradigm. Science (2009) 5.45
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature (2011) 5.45
A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell (2009) 5.40
Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34. J Invest Dermatol (2003) 5.28
Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells. Nature (1963) 5.23
Long-term propagation of distinct hematopoietic differentiation programs in vivo. Cell Stem Cell (2007) 5.14
Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell (2008) 5.02
Intestinal stem cells protect their genome by selective segregation of template DNA strands. J Cell Sci (2002) 4.92
Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet (2011) 4.85
Intestinal label-retaining cells are secretory precursors expressing Lgr5. Nature (2013) 4.83
Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin. Science (2010) 4.45
Evolution of the cancer stem cell model. Cell Stem Cell (2014) 4.38
Interconversion between intestinal stem cell populations in distinct niches. Science (2011) 4.23
Dynamics between stem cells, niche, and progeny in the hair follicle. Cell (2011) 4.14
Dominant role of the niche in melanocyte stem-cell fate determination. Nature (2002) 4.05
Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche. Cell (2011) 4.04
Distinct stem cell populations regenerate the follicle and interfollicular epidermis. Dev Cell (2005) 3.98
Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells. Proc Natl Acad Sci U S A (2010) 3.94
Epidermal stem cells of the skin. Annu Rev Cell Dev Biol (2006) 3.92
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Cell (2012) 3.91
NFATc1 balances quiescence and proliferation of skin stem cells. Cell (2008) 3.81
The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations. Proc Natl Acad Sci U S A (2011) 3.80
Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. Cell (2006) 3.79
Keratin 15 promoter targets putative epithelial stem cells in the hair follicle bulge. J Invest Dermatol (2003) 3.72
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers. EMBO J (2012) 3.70
Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell (2010) 3.69
Adipocyte lineage cells contribute to the skin stem cell niche to drive hair cycling. Cell (2011) 3.68
Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration. Nature (2012) 3.53
Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Cell Stem Cell (2009) 3.44
Distinct contribution of stem and progenitor cells to epidermal maintenance. Nature (2012) 3.44
Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci U S A (2010) 3.41
Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci U S A (2014) 3.39
Dll1+ secretory progenitor cells revert to stem cells upon crypt damage. Nat Cell Biol (2012) 3.30
A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage. Cell (2012) 3.21
Nerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells. Cell Stem Cell (2011) 3.19
Clonal dynamics of native haematopoiesis. Nature (2014) 3.15
The segregation of DNA in epithelial stem cells. Cell (1978) 3.12
Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging. Nature (2014) 3.09
Arteriolar niches maintain haematopoietic stem cell quiescence. Nature (2013) 3.07
Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment. J Exp Med (2010) 2.98
Identification of the cell lineage at the origin of basal cell carcinoma. Nat Cell Biol (2010) 2.97
Multiple classes of stem cells in cutaneous epithelium: a lineage analysis of adult mouse skin. EMBO J (2001) 2.89
Epidermal stem cells arise from the hair follicle after wounding. FASEB J (2007) 2.81
Lhx2 maintains stem cell character in hair follicles. Science (2006) 2.78
Long-term renewal of hair follicles from clonogenic multipotent stem cells. Proc Natl Acad Sci U S A (2005) 2.67
Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nat Cell Biol (2012) 2.51
Spatial organization within a niche as a determinant of stem-cell fate. Nature (2013) 2.49
SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors. Cell Stem Cell (2013) 2.47
Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells. Cell (2013) 2.42
Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential. Blood (2009) 2.41
Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis. Nat Cell Biol (2013) 2.40
Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium. J Cell Biol (2011) 2.21
Lgr5+ stem cells are indispensable for radiation-induced intestinal regeneration. Cell Stem Cell (2013) 2.20
Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. Cell Stem Cell (2014) 2.18
Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium. Cell (2013) 2.10
Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia. Nat Genet (2009) 2.07
A distinct population of clonogenic and multipotent murine follicular keratinocytes residing in the upper isthmus. J Cell Sci (2008) 2.06
Slowly cycling (label-retaining) epidermal cells behave like clonogenic stem cells in vitro. Cell Prolif (1994) 2.05
The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells. Development (2006) 2.04
Deterministic regulation of hematopoietic stem cell self-renewal and differentiation. Blood (2002) 2.04
Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging. Cell Stem Cell (2013) 1.97
Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy. Nature (2013) 1.94
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis. Cell Stem Cell (2014) 1.91
Long-lived intestinal tuft cells serve as colon cancer-initiating cells. J Clin Invest (2014) 1.90
Multipotent and unipotent progenitors contribute to prostate postnatal development. Nat Cell Biol (2012) 1.89
The basement membrane of hair follicle stem cells is a muscle cell niche. Cell (2011) 1.88
Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential. Cell Stem Cell (2010) 1.87
Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness. Blood (2004) 1.84
Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1). Proc Natl Acad Sci U S A (2012) 1.83
Life span of multipotential hematopoietic stem cells in vivo. J Exp Med (1990) 1.82
Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire. Cell Stem Cell (2013) 1.80
CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age. Blood (2013) 1.74