Published in Biochem Pharmacol on April 28, 2015
Altered nocifensive behavior in animal models of autism spectrum disorder: The role of the nicotinic cholinergic system. Neuropharmacology (2016) 0.83
The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain. Br J Pharmacol (2016) 0.76
Interactions between the endocannabinoid and nicotinic cholinergic systems: preclinical evidence and therapeutic perspectives. Psychopharmacology (Berl) (2016) 0.75
Plasticity in Brainstem Mechanisms of Pain Modulation by Nicotinic Acetylcholine Receptors in the Rat. eNeuro (2017) 0.75
Competition, Selectivity and Efficacy of Analogs of A-84543 for Nicotinic Acetylcholine Receptors with Repositioning of Pyridine Nitrogen. Neurochem Res (2015) 0.75
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81
Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods (1994) 23.05
Intrathecal morphine in mice: a new technique. Eur J Pharmacol (1980) 5.99
Habenular α5 nicotinic receptor subunit signalling controls nicotine intake. Nature (2011) 3.77
The affective component of pain in rodents: direct evidence for a contribution of the anterior cingulate cortex. Proc Natl Acad Sci U S A (2001) 2.71
alpha 5 Subunit alters desensitization, pharmacology, Ca++ permeability and Ca++ modulation of human neuronal alpha 3 nicotinic receptors. J Pharmacol Exp Ther (1998) 2.33
Structural and functional diversity of native brain neuronal nicotinic receptors. Biochem Pharmacol (2009) 2.33
Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice. J Neurosci (2009) 2.30
Functional contributions of alpha5 subunit to neuronal acetylcholine receptor channels. Nature (1996) 2.06
Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs. J Pharmacol Exp Ther (2008) 2.04
The cholinergic anti-inflammatory pathway: a missing link in neuroimmunomodulation. Mol Med (2003) 2.00
The nicotinic acetylcholine receptor subunit alpha 5 mediates short-term effects of nicotine in vivo. Mol Pharmacol (2003) 2.00
The contribution of excitatory amino acids to central sensitization and persistent nociception after formalin-induced tissue injury. J Neurosci (1992) 1.93
Ca2+ permeability of the (alpha4)3(beta2)2 stoichiometry greatly exceeds that of (alpha4)2(beta2)3 human acetylcholine receptors. Mol Pharmacol (2006) 1.91
A randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of ABT-594 in patients with diabetic peripheral neuropathic pain. Pain (2009) 1.64
Nicotinic alpha5 subunit deletion locally reduces high-affinity agonist activation without altering nicotinic receptor numbers. J Neurochem (2007) 1.57
Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice. J Pharmacol Exp Ther (2010) 1.57
The alpha4beta2alpha5 nicotinic cholinergic receptor in rat brain is resistant to up-regulation by nicotine in vivo. J Neurochem (2007) 1.53
Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice. J Pharmacol Exp Ther (1975) 1.52
Dorsal root ganglion neurons express multiple nicotinic acetylcholine receptor subtypes. J Neurophysiol (2001) 1.42
A behavioral test paradigm to measure the aversive quality of inflammatory and neuropathic pain in rats. Exp Neurol (2000) 1.22
Mice lacking neuronal nicotinic acetylcholine receptor beta4-subunit and mice lacking both alpha5- and beta4-subunits are highly resistant to nicotine-induced seizures. Physiol Genomics (2004) 1.17
Cytokine-mediated inflammatory hyperalgesia limited by interleukin-10. Br J Pharmacol (1995) 1.17
Diversity and distribution of nicotinic acetylcholine receptors in the locus ceruleus neurons. Proc Natl Acad Sci U S A (1999) 1.15
Peripheral nerve injury induces trans-synaptic modification of channels, receptors and signal pathways in rat dorsal spinal cord. Eur J Neurosci (2004) 1.13
Autonomic function in mice lacking alpha5 neuronal nicotinic acetylcholine receptor subunit. J Physiol (2002) 1.03
Neuronal nicotinic receptors as targets for novel analgesics. Expert Opin Investig Drugs (2005) 1.02
Increased severity of experimental colitis in alpha 5 nicotinic acetylcholine receptor subunit-deficient mice. Neuroreport (2005) 1.00
The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse. Neuropharmacology (2013) 0.97
Function of human α3β4α5 nicotinic acetylcholine receptors is reduced by the α5(D398N) variant. J Biol Chem (2012) 0.97
Nicotinic acetylcholine receptor distribution in relation to spinal neurotransmission pathways. J Comp Neurol (2003) 0.95
Central nociceptive role of prostacyclin (IP) receptor induced by peripheral inflammation. Neuroreport (2002) 0.91
Tonic nicotinic modulation of serotoninergic transmission in the spinal cord. Proc Natl Acad Sci U S A (2001) 0.91
Nicotinic receptor mutant mice in the study of autonomic function. Curr Drug Targets CNS Neurol Disord (2002) 0.90
Knock down of the alpha 5 nicotinic acetylcholine receptor in spinal nerve-ligated rats alleviates mechanical allodynia. Pharmacol Biochem Behav (2004) 0.90
Plasticity of spinal nicotinic acetylcholine receptors following spinal nerve ligation. Neurosci Res (2004) 0.89
Immunocytochemical localization of the alpha3, alpha4, alpha5, alpha7, beta2, beta3 and beta4 nicotinic acetylcholine receptor subunits in the locus coeruleus of the rat. Brain Res (2003) 0.88
Efficacy and safety of the α4β2 neuronal nicotinic receptor agonist ABT-894 in patients with diabetic peripheral neuropathic pain. Pain (2012) 0.86
Is the second phase of the formalin test useful to predict activity in chronic constriction injury models? A pharmacological comparison in different species. Pain Pract (2003) 0.86
The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acute and tonic pain models. J Pharmacol Exp Ther (2012) 0.86
Peripheral nerve injury alters spinal nicotinic acetylcholine receptor pharmacology. Eur J Pharmacol (2008) 0.84
The brain nicotinic acetylcholine receptor gene family. Prog Brain Res (1990) 0.83
Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons. Mol Pain (2014) 0.82
Population pharmacokinetics of ABT-594 in subjects with diabetic peripheral neuropathic pain. J Clin Pharm Ther (2011) 0.77