Anti-Lung Cancer Activity of the Curcumin Analog JZ534 In Vitro.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 4419220)

Published in Biomed Res Int on April 21, 2015

Authors

Jianzhang Wu1, Zhijian Cai2, Xiaoyan Wei1, Minxiao Chen2, Shilong Ying1, Lingyi Shi1, Ren-Ai Xu3, Fan He1, Guang Liang1, Xiuhua Zhang3

Author Affiliations

1: Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
2: Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China ; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.
3: Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.

Articles cited by this

Global cancer statistics, 2002. CA Cancer J Clin (2005) 119.22

Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin (2011) 30.81

Bioavailability of curcumin: problems and promises. Mol Pharm (2007) 8.72

Multidisciplinary management of lung cancer. N Engl J Med (2004) 7.13

Curcumin: the Indian solid gold. Adv Exp Med Biol (2007) 4.12

Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. Nat Med (2002) 3.54

Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med (1998) 3.42

Curcumin and cancer: an "old-age" disease with an "age-old" solution. Cancer Lett (2008) 3.14

Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products. Cancer Res (2007) 2.95

Pharmacokinetics and pharmacodynamics of curcumin. Adv Exp Med Biol (2007) 1.68

Biological effects of curcumin and its role in cancer chemoprevention and therapy. Anticancer Agents Med Chem (2006) 1.62

Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction. FEBS Lett (2002) 1.55

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer. Pharmacol Rev (2013) 1.11

Antitumor, anti-invasion, and antimetastatic effects of curcumin. Adv Exp Med Biol (2007) 1.10

Expression profiles of apoptotic genes induced by curcumin in human breast cancer and mammary epithelial cell lines. Anticancer Res (2005) 1.09

Inhibition of pancreatic and lung adenocarcinoma cell survival by curcumin is associated with increased apoptosis, down-regulation of COX-2 and EGFR and inhibition of Erk1/2 activity. Anticancer Res (2007) 1.08

Regulatory effect of the AMPK-COX-2 signaling pathway in curcumin-induced apoptosis in HT-29 colon cancer cells. Ann N Y Acad Sci (2009) 1.04

Acquired resistance to targeted therapies against oncogene-driven non-small-cell lung cancer: approach to subtyping progressive disease and clinical implications. Clin Lung Cancer (2013) 1.01

A novel monocarbonyl analogue of curcumin, (1E,4E)-1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one, induced cancer cell H460 apoptosis via activation of endoplasmic reticulum stress signaling pathway. J Med Chem (2011) 0.99

Effect of tumor size on prognosis in patients treated with radical radiotherapy or chemoradiotherapy for non-small cell lung cancer. An analysis of the staging project database of the International Association for the Study of Lung Cancer. J Thorac Oncol (2013) 0.98

Promising curcumin-based drug design: mono-carbonyl analogues of curcumin (MACs). Curr Pharm Des (2013) 0.91

PAC, a novel curcumin analogue, has anti-breast cancer properties with higher efficiency on ER-negative cells. Breast Cancer Res Treat (2010) 0.88

Sensitization of head and neck cancer to cisplatin through the use of a novel curcumin analog. Arch Otolaryngol Head Neck Surg (2011) 0.88

B19, a novel monocarbonyl analogue of curcumin, induces human ovarian cancer cell apoptosis via activation of endoplasmic reticulum stress and the autophagy signaling pathway. Int J Biol Sci (2013) 0.88

Multidrug resistance-associated protein 3 confers resistance to chemoradiotherapy for rectal cancer by regulating reactive oxygen species and caspase-3-dependent apoptotic pathway. Cancer Lett (2014) 0.85

Anticancer effect of a curcumin derivative B63: ROS production and mitochondrial dysfunction. Curr Cancer Drug Targets (2014) 0.84

Inhibition of cellular proliferation and induction of apoptosis by curcumin in human malignant astrocytoma cell lines. J Neurooncol (2005) 0.83

A novel mono-carbonyl analogue of curcumin induces apoptosis in ovarian carcinoma cells via endoplasmic reticulum stress and reactive oxygen species production. Mol Med Rep (2011) 0.81

Bax-alpha promotes apoptosis induced by cancer chemotherapy and accelerates the activation of caspase 3-like cysteine proteases in p53 double mutant B lymphoma Namalwa cells. Cell Death Differ (1998) 0.80

[Lung cancer, a worrying epidemiological evolution]. Rev Infirm (2012) 0.77