Published in Eur J Hum Genet on May 27, 2015
Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health. Hum Reprod (2016) 0.84
Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence. Int J Epidemiol (2016) 0.81
Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility. Am J Hum Genet (2016) 0.79
Phenotype and Tissue Expression as a Function of Genetic Risk in Polycystic Ovary Syndrome. PLoS One (2017) 0.75
A method to customize population-specific arrays for genome-wide association testing. Eur J Hum Genet (2016) 0.75
SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics (2008) 15.77
Genotype imputation for genome-wide association studies. Nat Rev Genet (2010) 14.59
Ensembl 2012. Nucleic Acids Res (2011) 14.55
LocusZoom: regional visualization of genome-wide association scan results. Bioinformatics (2010) 13.54
HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res (2011) 11.03
The UCSC Genome Browser database: extensions and updates 2013. Nucleic Acids Res (2012) 9.02
Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet (2012) 6.97
Genome-wide efficient mixed-model analysis for association studies. Nat Genet (2012) 6.62
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Severely reduced female fertility in CD9-deficient mice. Science (2000) 2.80
wANNOVAR: annotating genetic variants for personal genomes via the web. J Med Genet (2012) 2.43
Functional annotation of noncoding sequence variants. Nat Methods (2014) 2.41
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
FSH signaling pathways in immature granulosa cells that regulate target gene expression: branching out from protein kinase A. Cell Signal (2006) 2.12
The UK Adult Twin Registry (TwinsUK Resource). Twin Res Hum Genet (2012) 1.81
Loci at chromosomes 13, 19 and 20 influence age at natural menopause. Nat Genet (2009) 1.72
Functional analysis of human promoter polymorphisms. Hum Mol Genet (2003) 1.69
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Hum Mol Genet (2009) 1.61
Genetic determinants of serum testosterone concentrations in men. PLoS Genet (2011) 1.45
The SLC22 family with transporters of organic cations, anions and zwitterions. Mol Aspects Med (2013) 1.45
A comparison of multivariate genome-wide association methods. PLoS One (2014) 1.38
Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. PLoS Genet (2011) 1.30
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet (2012) 1.23
Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine. J Biol Chem (2002) 1.10
The PPARs and PXRs: nuclear xenobiotic receptors that define novel hormone signaling pathways. Recent Prog Horm Res (1999) 1.04
FSHB promoter polymorphism within evolutionary conserved element is associated with serum FSH level in men. Hum Reprod (2008) 1.03
Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women. PLoS One (2012) 0.95
Oral conjugated equine estrogen increases plasma von Willebrand factor in postmenopausal women. J Am Coll Cardiol (2002) 0.93
A common polymorphism in the CYP3A7 gene is associated with a nearly 50% reduction in serum dehydroepiandrosterone sulfate levels. J Clin Endocrinol Metab (2005) 0.93
Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men. Hum Mol Genet (2012) 0.93
Genetically determined dosage of follicle-stimulating hormone (FSH) affects male reproductive parameters. J Clin Endocrinol Metab (2011) 0.89
Evidence for cycle-dependent expression of follicle-stimulating hormone receptor in human endometrium. Gynecol Endocrinol (2005) 0.88
Comparison of different methods for the measurement of serum testosterone in the aging male. Swiss Med Wkly (2004) 0.86
Sex hormone-binding globulin: gene organization and structure/function analyses. Horm Res (1996) 0.85
Genome-wide association study of sex hormones, gonadotropins and sex hormone-binding protein in Chinese men. J Med Genet (2013) 0.84
A human FSHB promoter SNP associated with low FSH levels in men impairs LHX3 binding and basal FSHB transcription. Endocrinology (2013) 0.84
Genomic organization of human fetal specific P-450IIIA7 (cytochrome P-450HFLa)-related gene(s) and interaction of transcriptional regulatory factor with its DNA element in the 5' flanking region. Biochim Biophys Acta (1992) 0.82
Estrogen stimulates von Willebrand factor production by cultured endothelial cells. Blood (1984) 0.80
Effects of the FSH-β-subunit promoter polymorphism -211G->T on the hypothalamic-pituitary-ovarian axis in normally cycling women indicate a gender-specific regulation of gonadotropin secretion. J Clin Endocrinol Metab (2012) 0.80
Genome-wide association studies on serum sex steroid levels. Mol Cell Endocrinol (2013) 0.77
Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet (2014) 5.78
DNA methylation and body-mass index: a genome-wide analysis. Lancet (2014) 5.49
Genome-wide association analyses identify variants in developmental genes associated with hypospadias. Nat Genet (2014) 1.93
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature (2014) 1.88
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet (2015) 1.87
Common variants associated with general and MMR vaccine-related febrile seizures. Nat Genet (2014) 1.81
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nat Genet (2017) 1.44
The genetic architecture of type 2 diabetes. Nature (2016) 1.43
Common variants at 12q15 and 12q24 are associated with infant head circumference. Nat Genet (2012) 1.36
Proton pump inhibitors alter the composition of the gut microbiota. Gut (2015) 1.28
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet (2016) 1.24
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet (2016) 1.20
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nat Genet (2015) 1.02
Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight. JAMA (2016) 1.00
A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum Mol Genet (2014) 0.98
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Hum Mol Genet (2015) 0.94
Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nat Genet (2016) 0.84
Paternal age and telomere length in twins: the germ stem cell selection paradigm. Aging Cell (2015) 0.80
Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairs. Clin Epigenetics (2016) 0.80
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nat Commun (2017) 0.80
ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins. BMC Genomics (2016) 0.79
Quantifying the extent to which index event biases influence large genetic association studies. Hum Mol Genet (2016) 0.78
Genome-wide association study identifies variants in HORMAD2 associated with tonsillectomy. J Med Genet (2016) 0.76
Blood, urine and faecal metabolite profiles in the study of adult renal disease. Arch Biochem Biophys (2015) 0.76
Autosomal genetic control of human gene expression does not differ across the sexes. Genome Biol (2016) 0.76
Improving vaccine safety through a better understanding of vaccine adverse events. Clin Infect Dis (2015) 0.76
Genetic regulation of gene expression in the epileptic human hippocampus. Hum Mol Genet (2017) 0.75
Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues. Nat Genet (2017) 0.75
Genome-Wide Association Shows that Pigmentation Genes Play a Role in Skin Aging. J Invest Dermatol (2017) 0.75
Effects of statins on the immunoglobulin G glycome. Biochim Biophys Acta (2017) 0.75
Epigenome-wide association of DNA methylation in whole blood with bone mineral density. J Bone Miner Res (2017) 0.75
Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans. Sci Rep (2017) 0.75
Higher Nevus Count Exhibits a Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma. J Invest Dermatol (2016) 0.75
Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand. Ann Rheum Dis (2017) 0.75