Genetic rearrangements of variable di-residue (RVD)-containing repeat arrays in a baculoviral TALEN system.

PubWeight™: 0.79‹?›

🔗 View Article (PMC 4362386)

Published in Mol Ther Methods Clin Dev on October 29, 2014

Authors

Cia-Hin Lau1, Haibao Zhu1, Johan Chin-Kang Tay1, Zhendong Li1, Felix Chang Tay1, Can Chen1, Wee-Kiat Tan1, Shouhui Du1, Vic-Ki Sia1, Rui-Zhe Phang1, Shin-Yi Tang1, Chiyun Yang1, Zhixia Chi1, Chieh-Ching Liang1, Er Ning1, Shu Wang2

Author Affiliations

1: Department of Biological Sciences, National University of Singapore , Singapore, Singapore.
2: Department of Biological Sciences, National University of Singapore , Singapore, Singapore ; Institute of Bioengineering and Nanotechnology , Singapore, Singapore.

Associated clinical trials:

Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 for HIV (Zinc-Finger) | NCT00842634

Phase 1 Dose Escalation Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Patients | NCT01044654

Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Subjects | NCT01252641

Articles cited by this

Multiplex genome engineering using CRISPR/Cas systems. Science (2013) 55.53

RNA-guided human genome engineering via Cas9. Science (2013) 48.29

A TALE nuclease architecture for efficient genome editing. Nat Biotechnol (2010) 26.47

Breaking the code of DNA binding specificity of TAL-type III effectors. Science (2009) 22.33

Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature (2005) 19.15

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nat Biotechnol (2009) 12.40

Genome-scale CRISPR-Cas9 knockout screening in human cells. Science (2013) 12.36

Genetic screens in human cells using the CRISPR-Cas9 system. Science (2013) 10.75

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery. Nat Biotechnol (2007) 9.23

In vivo genome editing using a high-efficiency TALEN system. Nature (2012) 7.11

Optical control of mammalian endogenous transcription and epigenetic states. Nature (2013) 6.09

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library. Nat Biotechnol (2013) 4.72

Efficient generation of infectious recombinant baculoviruses by site-specific transposon-mediated insertion of foreign genes into a baculovirus genome propagated in Escherichia coli. J Virol (1993) 4.61

The crystal structure of TAL effector PthXo1 bound to its DNA target. Science (2012) 3.69

Structural basis for sequence-specific recognition of DNA by TAL effectors. Science (2012) 3.64

A library of TAL effector nucleases spanning the human genome. Nat Biotechnol (2013) 2.87

Optimization of scarless human stem cell genome editing. Nucleic Acids Res (2013) 2.78

Preferential PCR amplification of alleles: mechanisms and solutions. PCR Methods Appl (1992) 2.47

Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells. Nucleic Acids Res (2012) 2.14

Efficient TALEN construction and evaluation methods for human cell and animal applications. Genes Cells (2013) 1.99

Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases. Mol Ther (2013) 1.49

Linear plasmid vector for cloning of repetitive or unstable sequences in Escherichia coli. Nucleic Acids Res (2009) 1.42

Repurposing CRISPR/Cas9 for in situ functional assays. Genes Dev (2013) 1.41

megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering. Nucleic Acids Res (2013) 1.30

The effect of the length of direct repeats and the presence of palindromes on deletion between directly repeated DNA sequences in bacteriophage T7. Nucleic Acids Res (1991) 1.29

In vitro replication slippage by DNA polymerases from thermophilic organisms. J Mol Biol (2001) 1.23

Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5. Hum Gene Ther (2013) 1.14

Population dynamics of an RNA virus and its defective interfering particles in passage cultures. Virol J (2010) 1.12

Integrase-defective lentiviral vectors as a delivery platform for targeted modification of adenosine deaminase locus. Mol Ther (2013) 1.08

Baculovirus: an insect-derived vector for diverse gene transfer applications. Mol Ther (2013) 1.07

Baculoviral vector-mediated transient and stable transgene expression in human embryonic stem cells. Stem Cells (2007) 1.07

Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing. Sci Rep (2013) 1.06

Versatile and efficient genome editing in human cells by combining zinc-finger nucleases with adeno-associated viral vectors. Hum Gene Ther (2011) 1.04

Genotyping of simple sequence repeats--factors implicated in shadow band generation revisited. Electrophoresis (2006) 0.98

Efficient recombinase-mediated cassette exchange at the AAVS1 locus in human embryonic stem cells using baculoviral vectors. Nucleic Acids Res (2011) 0.98

Gene editing of human embryonic stem cells via an engineered baculoviral vector carrying zinc-finger nucleases. Mol Ther (2011) 0.97

Host innate immune responses induced by baculovirus in mammals. Curr Gene Ther (2010) 0.96

Genetic requirements for homologous recombination in Autographa californica nucleopolyhedrovirus. J Virol (2002) 0.96

High-frequency homologous recombination between baculoviruses involves DNA replication. J Virol (2003) 0.94

Slipped misalignment mechanisms of deletion formation: analysis of deletion endpoints. J Mol Biol (1998) 0.93

High-efficiency transient transduction of human embryonic stem cell-derived neurons with baculoviral vectors. Mol Ther (2009) 0.89

Construction and characterization of adenoviral vectors for the delivery of TALENs into human cells. Methods (2014) 0.89

DNA replication promotes high-frequency homologous recombination during Autographa californica multiple nuclear polyhedrosis virus infection. Virology (1997) 0.88

Potential cancer gene therapy by baculoviral transduction. Curr Gene Ther (2010) 0.88

Baculovirus transduction of mesenchymal stem cells: in vitro responses and in vivo immune responses after cell transplantation. Mol Ther (2009) 0.87

Baculoviral transduction facilitates TALEN-mediated targeted transgene integration and Cre/LoxP cassette exchange in human-induced pluripotent stem cells. Nucleic Acids Res (2013) 0.87

Defective antiviral responses of induced pluripotent stem cells to baculoviral vector transduction. J Virol (2012) 0.87

Production of baculovirus defective interfering particles during serial passage is delayed by removing transposon target sites in fp25k. J Gen Virol (2011) 0.86

High frequency recombination between homologous baculoviruses in cell culture. Arch Virol (2000) 0.86

Targeted transgene insertion into the AAVS1 locus driven by baculoviral vector-mediated zinc finger nuclease expression in human-induced pluripotent stem cells. J Gene Med (2013) 0.85

Rapid assembly of customized TALENs into multiple delivery systems. PLoS One (2013) 0.83

Innate immune response induced by baculovirus attenuates transgene expression in mammalian cells. J Virol (2013) 0.81

Adaptive immune responses elicited by baculovirus and impacts on subsequent transgene expression in vivo. J Virol (2013) 0.81

Zinc finger nuclease-expressing baculoviral vectors mediate targeted genome integration of reprogramming factor genes to facilitate the generation of human induced pluripotent stem cells. Stem Cells Transl Med (2013) 0.80