CYP2C19 metabolizer status and clopidogrel efficacy in the Secondary Prevention of Small Subcortical Strokes (SPS3) study.

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Published in J Am Heart Assoc on May 27, 2015

Authors

Caitrin W McDonough1, Leslie A McClure2, Braxton D Mitchell3, Yan Gong1, Richard B Horenstein4, Joshua P Lewis4, Thalia S Field5, Robert L Talbert6, Oscar R Benavente5, Julie A Johnson7, Alan R Shuldiner3

Author Affiliations

1: Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL (C.W.M.D., Y.G., J.A.J.).
2: Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, AL (L.A.M.C.).
3: Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD (B.D.M., R.B.H., J.P.L., A.R.S.) Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD (B.D.M., R.B.H., J.P.L., A.R.S.) Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, Baltimore, MD (B.D.M., A.R.S.).
4: Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD (B.D.M., R.B.H., J.P.L., A.R.S.) Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD (B.D.M., R.B.H., J.P.L., A.R.S.).
5: Department of Neurology, University of British Columbia, Vancouver, British Columbia, Canada (T.S.F., O.R.B.).
6: College of Pharmacy, University of Texas at Austin, TX (R.L.T.).
7: Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL (C.W.M.D., Y.G., J.A.J.) Division of Cardiovascular Medicine, College of Medicine, University of Florida, Gainesville, FL (J.A.J.).

Associated clinical trials:

Secondary Prevention of Small Subcortical Strokes Trial (SPS3) | NCT00059306

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