Efficacy of fewer than three doses of an HPV-16/18 AS04-adjuvanted vaccine: combined analysis of data from the Costa Rica Vaccine and PATRICIA trials.

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Published in Lancet Oncol on June 09, 2015

Authors

Aimée R Kreimer1, Frank Struyf2, Maria Rowena Del Rosario-Raymundo3, Allan Hildesheim4, S Rachel Skinner5, Sholom Wacholder4, Suzanne M Garland6, Rolando Herrero7, Marie-Pierre David2, Cosette M Wheeler8, Costa Rica Vaccine Trial Study Group Authors, Paula González, Silvia Jiménez, Douglas R Lowy, Ligia A Pinto, Caroline Porras, Ana Cecilia Rodriguez, Mahboobeh Safaeian, Mark Schiffman, John T Schiller, John Schussler, Mark E Sherman, PATRICIA Study Group Authors, F Xavier Bosch, Xavier Castellsague, Archana Chatterjee, Song-Nan Chow, Dominique Descamps, Francisco Diaz-Mitoma, Gary Dubin, Maria Julieta Germar, Diane M Harper, David J M Lewis, Genara Limson, Paulo Naud, Klaus Peters, Willy A J Poppe, Brian Ramjattan, Barbara Romanowski, Jorge Salmeron, Tino F Schwarz, Julio C Teixeira, Wiebren A A Tjalma, HPV PATRICIA Principal Investigators/Co-Principal Investigator Collaborators, GSK Vaccines Clinical Study Support Group

Author Affiliations

1: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: kreimera@mail.nih.gov.
2: GSK Vaccines, Wavre, Belgium.
3: Department of Obstetrics and Gynecology, San Pablo Colleges Medical Center, San Pablo City, Philippines.
4: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
5: Vaccine Trials Group, Telethon Institute for Child Health Research, Perth, WA, Australia; Sydney University Discipline of Paediatrics and Child Health, Children's Hospital at Westmead, Sydney, NSW, Australia.
6: Microbiology and Infectious Diseases Department, Royal Women's Hospital and Department of Obstetrics and Gynaecology, University of Melbourne, Murdoch Childrens Research Institute Melbourne, VIC, Australia.
7: Proyecto Epidemiologico Guanacaste, San José, Costa Rica; Section of Early Detection and Prevention, International Agency for Research on Cancer, Lyon, France.
8: Departments of Pathology and Obstetrics and Gynecology, University of New Mexico Health Sciences Center, Albuquerque, NM, USA. Electronic address: cwheeler@salud.unm.edu.

Associated clinical trials:

Human Papilloma Virus (HPV) Vaccine Efficacy Trial Against Cervical Pre-cancer in Young Adults With GlaxoSmithKline (GSK) Biologicals HPV-16/18 | NCT00122681

Vaccine To Prevent Cervical Intraepithelial Neoplasia or Cervical Cancer in Younger Healthy Participants | NCT00128661

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