Published in EBioMedicine on February 26, 2015
Compassionate Use Protocol for the Treatment of Autoinflammatory Syndromes | NCT01724580
Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases. Nat Rev Rheumatol (2015) 1.11
Pharmacologic inhibition of JAK-STAT signaling promotes hair growth. Sci Adv (2015) 0.89
Type I interferon-mediated monogenic autoinflammation: The type I interferonopathies, a conceptual overview. J Exp Med (2016) 0.86
Trisomy 21 consistently activates the interferon response. Elife (2016) 0.85
Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata. JCI Insight (2016) 0.80
Oral ruxolitinib induces hair regrowth in patients with moderate-to-severe alopecia areata. JCI Insight (2016) 0.78
Molecular signatures define alopecia areata subtypes and transcriptional biomarkers. EBioMedicine (2016) 0.78
Understanding autoimmunity of vitiligo and alopecia areata. Curr Opin Pediatr (2016) 0.76
Treatment of an alopecia areata patient with tofacitinib results in regrowth of hair and changes in serum and skin biomarkers. Exp Dermatol (2016) 0.76
Translational Positioning of Janus Kinase (JAK) Inhibitors in Alopecia Areata. EBioMedicine (2015) 0.75
Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies. Autoimmun Rev (2016) 0.75
Alopecia Areata: An Update on Treatment Options for Children. Paediatr Drugs (2017) 0.75
Alopecia areata. Nat Rev Dis Prim (2017) 0.75
[Familial chilblain lupus : Type 1 interferonopathy with model character]. Z Rheumatol (2017) 0.75
Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis. N Engl J Med (2010) 8.77
Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritis. N Engl J Med (2012) 4.16
Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition. Nat Med (2014) 3.54
Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. Nature (2010) 2.85
PSMB8 encoding the β5i proteasome subunit is mutated in joint contractures, muscle atrophy, microcytic anemia, and panniculitis-induced lipodystrophy syndrome. Am J Hum Genet (2010) 2.05
Mutations in proteasome subunit β type 8 cause chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature with evidence of genetic and phenotypic heterogeneity. Arthritis Rheum (2012) 1.87
A randomized phase 2a efficacy and safety trial of the topical Janus kinase inhibitor tofacitinib in the treatment of chronic plaque psoriasis. Br J Dermatol (2013) 1.83
Proteasome assembly defect due to a proteasome subunit beta type 8 (PSMB8) mutation causes the autoinflammatory disorder, Nakajo-Nishimura syndrome. Proc Natl Acad Sci U S A (2011) 1.80
Killing two birds with one stone: oral tofacitinib reverses alopecia universalis in a patient with plaque psoriasis. J Invest Dermatol (2014) 1.73
Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci. Nat Commun (2015) 1.32
Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE) syndrome. J Am Acad Dermatol (2010) 1.25
Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature syndrome: a case report. Pediatr Dermatol (2010) 1.17
Alopecia areata: Clinical presentation, diagnosis, and unusual cases. Dermatol Ther (2011) 1.16
Interferon-gamma-deficient mice are resistant to the development of alopecia areata. Br J Dermatol (2006) 1.10
Preliminary clinical activity of a topical JAK1/2 inhibitor in the treatment of psoriasis. J Am Acad Dermatol (2012) 1.09
Ruxolitinib-induced reversal of alopecia universalis in a patient with essential thrombocythemia. Am J Hematol (2015) 1.01
Type 1 interferon signature in the scalp lesions of alopecia areata. Br J Dermatol (2010) 0.95
Zosteriform cutaneous leishmaniasis diagnosed with the help of dermoscopy. Dermatol Pract Concept (2014) 1.01
An extraordinary colocalization of alopecia areata and vitiligo. Int J Trichology (2010) 0.99
Spermidine promotes human hair growth and is a novel modulator of human epithelial stem cell functions. PLoS One (2011) 0.86
Regrowth of black hair in two red-haired alopecia areata patients. Australas J Dermatol (2012) 0.81
Identification of distinct mutations in AAGAB in families with type 1 punctate palmoplantar keratoderma. J Invest Dermatol (2014) 0.79
Molecular signatures define alopecia areata subtypes and transcriptional biomarkers. EBioMedicine (2016) 0.78
Early-onset sensorineural hearing loss is a prominent feature of H syndrome. Int J Pediatr Otorhinolaryngol (2010) 0.76
Pemphigus vulgaris with loss of hair on the scalp. Int J Trichology (2013) 0.76
Treatment of an alopecia areata patient with tofacitinib results in regrowth of hair and changes in serum and skin biomarkers. Exp Dermatol (2016) 0.76
Atypical "allergic crease". J Dermatol Case Rep (2010) 0.75
Commentary on: Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis. Exp Dermatol (2013) 0.75
Renbök phenomenon in an alopecia areata patient with psoriasis. Int J Trichology (2013) 0.75
Severe Facial Hirsutism Following Isotretinoin Therapy: An Under-reported Entity. Int J Trichology (2015) 0.75
Two Episodes of Simultaneous Identical Alopecia Areata in Identical Twins. Int J Trichology (2016) 0.75
Alopecia areata and down syndrome: a true association or a coincidence. Int J Trichology (2013) 0.75
Skin manifestations of primary hyperoxaluria: a case report. Int J Dermatol (2015) 0.75
Atopic Dermatitis in Israeli Adolescents from 1998 to 2013: Trends in Time and Association with Migraine. Pediatr Dermatol (2017) 0.75
A spermidine-based nutritional supplement prolongs the anagen phase of hair follicles in humans: a randomized, placebo-controlled, double-blind study. Dermatol Pract Concept (2017) 0.75
A systematic review of pulse steroid therapy for alopecia areata. J Am Acad Dermatol (2016) 0.75
Therapy with eculizumab for patients with CD59 p.Cys89Tyr mutation. Ann Neurol (2016) 0.75
Successful treatment of refractory Darier disease with alitretinoin with a follow up of over a year: a case report. Dermatol Ther (2016) 0.75
Rapid Clearance of Necrolytic Migratory Erythema Following Intravenous Administration of Amino Acids. JAMA Dermatol (2016) 0.75
Re-evaluation of epidermodysplasia verruciformis: Reconciling more than 90 years of debate. J Am Acad Dermatol (2017) 0.75
p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis. J Invest Dermatol (2015) 0.75
E-cadherin-mediated Cell Contact Controls the Epidermal Damage Response in Radiation Dermatitis. J Invest Dermatol (2017) 0.75