Published in J Allergy Clin Immunol on July 01, 2015
International consensus (ICON) on: clinical consequences of mite hypersensitivity, a global problem. World Allergy Organ J (2017) 0.83
Indoor Allergens and Allergic Respiratory Disease. Curr Allergy Asthma Rep (2016) 0.82
The Protein Data Bank. Nucleic Acids Res (2000) 187.10
Pfam: the protein families database. Nucleic Acids Res (2013) 22.48
HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes. Acta Crystallogr D Biol Crystallogr (2006) 13.29
Towards automated crystallographic structure refinement with phenix.refine. Acta Crystallogr D Biol Crystallogr (2012) 11.31
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature (2009) 8.99
Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution. Nature (1965) 8.13
Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med (2002) 6.48
A three-dimensional model of the myoglobin molecule obtained by x-ray analysis. Nature (1958) 5.64
The lipocalin protein family: structure and function. Biochem J (1996) 5.24
Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature (2008) 4.85
Structure of haemoglobin: a three-dimensional Fourier synthesis at 5.5-A. resolution, obtained by X-ray analysis. Nature (1960) 3.80
Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system. Cell (2008) 3.72
Structure of the human histamine H1 receptor complex with doxepin. Nature (2011) 3.48
The effect of component-resolved diagnosis on specific immunotherapy prescription in children with hay fever. J Allergy Clin Immunol (2014) 2.75
Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma. J Immunol (2004) 2.67
Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions. J Clin Invest (1999) 2.53
Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser. Nature (2014) 2.53
X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy. Nat Struct Biol (1996) 2.25
Pheromone binding to two rodent urinary proteins revealed by X-ray crystallography. Nature (1992) 2.20
MyD88-dependent induction of allergic Th2 responses to intranasal antigen. J Clin Invest (2005) 2.20
The structural biology of Toll-like receptors. Structure (2011) 2.04
Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web server. Nat Protoc (2013) 1.85
Structure of the E. coli ribosome-EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM. Nature (2015) 1.83
Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways. J Lipid Res (2012) 1.79
Allergens are distributed into few protein families and possess a restricted number of biochemical functions. J Allergy Clin Immunol (2008) 1.77
Strategies for macromolecular synchrotron crystallography. Structure (2000) 1.75
Dust mite proteolytic allergens induce cytokine release from cultured airway epithelium. J Immunol (1998) 1.73
A molecular perspective on TH2-promoting cytokine receptors in patients with allergic disease. J Allergy Clin Immunol (2013) 1.73
Protein crystallography for non-crystallographers, or how to get the best (but not more) from published macromolecular structures. FEBS J (2007) 1.70
Protein folds and functions. Structure (1998) 1.69
Molecular profiles of IgE to Phleum pratense in children with grass pollen allergy: implications for specific immunotherapy. J Allergy Clin Immunol (2011) 1.67
Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues. Immunity (1998) 1.67
Engineering of the major house dust mite allergen Der f 2 for allergen-specific immunotherapy. Nat Biotechnol (1997) 1.63
Dominant epitopes and allergic cross-reactivity: complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1. J Immunol (2000) 1.46
Nomenclature and structural biology of allergens. J Allergy Clin Immunol (2006) 1.45
Cross-reactivity of IgE antibodies to allergens. Allergy (2001) 1.42
The crystal structure of a major dust mite allergen Der p 2, and its biological implications. J Mol Biol (2002) 1.37
High-affinity IgE recognition of a conformational epitope of the major respiratory allergen Phl p 2 as revealed by X-ray crystallography. J Immunol (2009) 1.37
A major house dust mite allergen disrupts the immunoglobulin E network by selectively cleaving CD23: innate protection by antiproteases. J Exp Med (1995) 1.36
Crystal structure of a dimerized cockroach allergen Bla g 2 complexed with a monoclonal antibody. J Biol Chem (2008) 1.35
Molecular interactions between a recombinant IgE antibody and the beta-lactoglobulin allergen. Structure (2007) 1.33
Proteases as Th2 adjuvants. Curr Allergy Asthma Rep (2007) 1.30
Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcɛRI. Nat Struct Mol Biol (2011) 1.29
Quantification of specific IgE to whole peanut extract and peanut components in prediction of peanut allergy. J Allergy Clin Immunol (2011) 1.29
Structure of the major peanut allergen Ara h 1 may protect IgE-binding epitopes from degradation. J Immunol (2000) 1.26
Increasing the accuracy of peanut allergy diagnosis by using Ara h 2. J Allergy Clin Immunol (2012) 1.26
Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis. J Immunol (2003) 1.25
Avoidable errors in deposited macromolecular structures: an impediment to efficient data mining. IUCrJ (2014) 1.25
The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins. J Allergy Clin Immunol (2010) 1.20
The molecular basis of allergenicity. Trends Immunol (2008) 1.19
How molecular diagnosis can change allergen-specific immunotherapy prescription in a complex pollen area. Allergy (2012) 1.16
Crystal structure of cockroach allergen Bla g 2, an unusual zinc binding aspartic protease with a novel mode of self-inhibition. J Mol Biol (2005) 1.15
Der p I, a major allergen of the house dust mite, proteolytically cleaves the low-affinity receptor for human IgE (CD23). Eur J Immunol (1995) 1.14
The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family. J Biol Chem (2003) 1.11
Cockroach allergen Bla g 2: structure, function, and implications for allergic sensitization. Am J Respir Crit Care Med (2002) 1.11
The utility of peanut components in the diagnosis of IgE-mediated peanut allergy among distinct populations. J Allergy Clin Immunol Pract (2012) 1.08
IgE cross-reactivity between the major peanut allergen Ara h 2 and the nonhomologous allergens Ara h 1 and Ara h 3. J Allergy Clin Immunol (2013) 1.07
Identification of a B-cell epitope of hyaluronidase, a major bee venom allergen, from its crystal structure in complex with a specific Fab. J Mol Biol (2007) 1.06
Determination of protein structures--a series of fortunate events. Biophys J (2008) 1.06
Reshaping the Bet v 1 fold modulates T(H) polarization. J Allergy Clin Immunol (2011) 1.05
Molecular determinants for antibody binding on group 1 house dust mite allergens. J Biol Chem (2011) 1.05
Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI. Proc Natl Acad Sci U S A (2012) 1.04
Structural and immunologic characterization of Ara h 1, a major peanut allergen. J Biol Chem (2011) 1.03
Crystal structures of mite allergens Der f 1 and Der p 1 reveal differences in surface-exposed residues that may influence antibody binding. J Mol Biol (2008) 1.03
Update of the WHO/IUIS Allergen Nomenclature Database based on analysis of allergen sequences. Allergy (2014) 1.02
Crystal structure of small protein crambin at 0.48 Å resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 1.02
Naturally occurring hypoallergenic Bet v 1 isoforms fail to induce IgE responses in individuals with birch pollen allergy. J Allergy Clin Immunol (2007) 1.01
Guilt by intimate association: what makes an allergen an allergen? J Allergy Clin Immunol (2010) 1.00
Annotating proteins with generalized functional linkages. Proc Natl Acad Sci U S A (2008) 0.96
Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity. Allergy (2011) 0.95
Der p 5 crystal structure provides insight into the group 5 dust mite allergens. J Biol Chem (2010) 0.94
Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding. PLoS One (2011) 0.94
Structural characterization of the tetrameric form of the major cat allergen Fel d 1. J Mol Biol (2007) 0.93
Recombinant allergens for specific immunotherapy. J Allergy Clin Immunol (2011) 0.93
Carbohydrates contribute to the interactions between cockroach allergen Bla g 2 and a monoclonal antibody. J Immunol (2010) 0.93
To automate or not to automate: this is the question. J Struct Funct Genomics (2010) 0.93
Diagnostic accuracy of specific IgE to components in diagnosing peanut allergy: a systematic review. Clin Exp Allergy (2015) 0.93
Impact of synchrotron radiation on macromolecular crystallography: a personal view. J Synchrotron Radiat (2010) 0.93
Alternaria alternata allergen Alt a 1: a unique β-barrel protein dimer found exclusively in fungi. J Allergy Clin Immunol (2012) 0.91
The novel structure of the cockroach allergen Bla g 1 has implications for allergenicity and exposure assessment. J Allergy Clin Immunol (2013) 0.91
Randomized double-blind controlled study with sublingual carbamylated allergoid immunotherapy in mild rhinitis due to mites. Allergy (2006) 0.91
Kiwifruit Act d 11 is the first member of the ripening-related protein family identified as an allergen. Allergy (2011) 0.89
Bla g 6: a troponin C allergen from Blattella germanica with IgE binding calcium dependence. J Allergy Clin Immunol (2006) 0.89
Early childhood IgE reactivity to pathogenesis-related class 10 proteins predicts allergic rhinitis in adolescence. J Allergy Clin Immunol (2014) 0.89
Animal-derived lipocalin allergens exhibit immunoglobulin E cross-reactivity. Clin Exp Allergy (2007) 0.87
Structural features of allergenic molecules. Chem Immunol Allergy (2006) 0.87
The cross-reactive calcium-binding pollen allergen, Phl p 7, reveals a novel dimer assembly. EMBO J (2002) 0.87
Kiwifruit allergy across Europe: clinical manifestation and IgE recognition patterns to kiwifruit allergens. J Allergy Clin Immunol (2012) 0.86
Data management in the modern structural biology and biomedical research environment. Methods Mol Biol (2014) 0.86
Recombinant allergens for immunotherapy: a Der p 2 variant with reduced IgE reactivity retains T-cell epitopes. J Allergy Clin Immunol (1998) 0.85
The future of crystallography in drug discovery. Expert Opin Drug Discov (2013) 0.84
Human immunoglobulin E flexes between acutely bent and extended conformations. Nat Struct Mol Biol (2014) 0.84
The structure of latherin, a surfactant allergen protein from horse sweat and saliva. J R Soc Interface (2013) 0.83
Ca2+-dependent structural changes in the B-cell receptor CD23 increase its affinity for human immunoglobulin E. J Biol Chem (2013) 0.83
Do lipids influence the allergic sensitization process? J Allergy Clin Immunol (2014) 0.83
Crystallography: Sources of inspiration. Nature (2014) 0.81
Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies. J Immunol (2015) 0.80
Analysis of glutathione S-transferase allergen cross-reactivity in a North American population: Relevance for molecular diagnosis. J Allergy Clin Immunol (2015) 0.80
Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5. J Mol Biol (2014) 0.78
Crystallography at 100. Going from strength to strength. Introduction. Science (2014) 0.78