DAPIT Over-Expression Modulates Glucose Metabolism and Cell Behaviour in HEK293T Cells.

PubWeight™: 2.02‹?› | Rank: Top 2%

🔗 View Article (PMC 4498893)

Published in PLoS One on July 10, 2015

Authors

Heidi Kontro1, Giuseppe Cannino2, Pierre Rustin3, Eric Dufour2, Heikki Kainulainen4

Author Affiliations

1: Tampere Centre for Child Health Research, University of Tampere, Tampere, Finland.
2: Institute of Biomedical Technology, University of Tampere, Tampere, Finland.
3: INSERM UMR 1141, Paris, France; Université Paris 7, Paris, France.
4: Department of Biology of Physical Activity, University of Jyväskylä, Jyväskylä, Finland.

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81

The landscape of somatic copy-number alteration across human cancers. Nature (2010) 31.88

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature (2012) 31.78

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature (2012) 20.47

Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci U S A (2007) 18.83

Initial genome sequencing and analysis of multiple myeloma. Nature (2011) 17.28

ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia (2004) 17.08

NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res (2012) 15.84

Regulation of cancer cell metabolism. Nat Rev Cancer (2011) 15.44

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell (2007) 14.58

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature (1998) 11.61

Frequent pathway mutations of splicing machinery in myelodysplasia. Nature (2011) 11.44

Biomarkers for epithelial-mesenchymal transitions. J Clin Invest (2009) 8.76

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases. Proc Natl Acad Sci U S A (2006) 7.00

Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Sci Transl Med (2010) 6.39

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nat Genet (2010) 6.10

Physiological roles of mitochondrial reactive oxygen species. Mol Cell (2012) 5.05

Biochemical and molecular investigations in respiratory chain deficiencies. Clin Chim Acta (1994) 4.93

Mitochondria and cancer. Nat Rev Cancer (2012) 4.81

A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets. Gut (2012) 4.51

Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation. Cancer Cell (2009) 4.47

Focal gains of VEGFA and molecular classification of hepatocellular carcinoma. Cancer Res (2008) 4.35

Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature (2012) 4.13

The many faces and functions of β-catenin. EMBO J (2012) 3.85

Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia. Mol Cell Biol (1998) 3.62

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5. J Mol Biol (2008) 3.27

Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney. Cancer Res (2009) 3.17

Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia. Nat Cell Biol (2007) 3.11

Changes in gene expression foreshadow diet-induced obesity in genetically identical mice. PLoS Genet (2006) 2.80

High-resolution global genomic survey of 178 gliomas reveals novel regions of copy number alteration and allelic imbalances. Cancer Res (2006) 2.56

Transcriptional integration of mitochondrial biogenesis. Trends Endocrinol Metab (2012) 2.34

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells. Nature (2014) 2.19

Hypoxia. 2. Hypoxia regulates cellular metabolism. Am J Physiol Cell Physiol (2010) 2.03

Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer. BMC Med Genomics (2009) 1.91

Molecular characterization of the pediatric preclinical testing panel. Clin Cancer Res (2008) 1.84

Genome-wide functional synergy between amplified and mutated genes in human breast cancer. Cancer Res (2008) 1.82

Oncometabolites: linking altered metabolism with cancer. J Clin Invest (2013) 1.78

Mitochondrial sirtuins. Biochim Biophys Acta (2010) 1.67

The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling. Mol Cell (2013) 1.54

Up-regulation of the ATPase inhibitory factor 1 (IF1) of the mitochondrial H+-ATP synthase in human tumors mediates the metabolic shift of cancer cells to a Warburg phenotype. J Biol Chem (2010) 1.49

The mitochondrial ATPase inhibitory factor 1 triggers a ROS-mediated retrograde prosurvival and proliferative response. Mol Cell (2012) 1.46

Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. Mol Cell Proteomics (2008) 1.46

Epithelial-mesenchymal transition, the tumor microenvironment, and metastatic behavior of epithelial malignancies. Int J Biochem Mol Biol (2012) 1.42

Three spectrophotometric assays for the measurement of the five respiratory chain complexes in minuscule biological samples. Clin Chim Acta (2006) 1.38

Identification of two proteins associated with mammalian ATP synthase. Mol Cell Proteomics (2007) 1.28

Staying alive: metabolic adaptations to quiescence. Cell Cycle (2012) 1.28

A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma. PLoS One (2011) 1.27

Superoxide-induced massive apoptosis in cultured skin fibroblasts harboring the neurogenic ataxia retinitis pigmentosa (NARP) mutation in the ATPase-6 gene of the mitochondrial DNA. Hum Mol Genet (2001) 1.15

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. Cancer Res (2010) 1.13

Redox regulation of mitochondrial biogenesis. Free Radic Biol Med (2012) 1.11

Knockdown of DAPIT (diabetes-associated protein in insulin-sensitive tissue) results in loss of ATP synthase in mitochondria. J Biol Chem (2011) 1.08

Hyperglycemia alters the schwann cell mitochondrial proteome and decreases coupled respiration in the absence of superoxide production. J Proteome Res (2010) 1.08

Association of two proteolipids of unknown function with ATP synthase from bovine heart mitochondria. FEBS Lett (2007) 1.03

DAPIT, a novel protein down-regulated in insulin-sensitive tissues in streptozotocin-induced diabetes. Acta Diabetol (2001) 0.97

Regulation of breast cancer stem cell features. Contemp Oncol (Pozn) (2015) 0.97

Role of caveolin 1, E-cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells. BMC Med Genomics (2008) 0.96

Gene expression profiling reveals sequential changes in gastric tubular adenoma and carcinoma in situ. World J Gastroenterol (2005) 0.90

Organization of Subunits in the Membrane Domain of the Bovine F-ATPase Revealed by Covalent Cross-linking. J Biol Chem (2015) 0.86

Glucose modulates respiratory complex I activity in response to acute mitochondrial dysfunction. J Biol Chem (2012) 0.86

Cellular and tissue expression of DAPIT, a phylogenetically conserved peptide. Eur J Histochem (2012) 0.85

Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthase. Mol Syst Biol (2014) 0.85

Degradation of IF1 controls energy metabolism during osteogenic differentiation of stem cells. EMBO Rep (2013) 0.83

Nucleolar proteins with altered expression in leukemic cell lines. Leuk Res (2011) 0.81