Plasma Tenofovir, Emtricitabine, and Rilpivirine and Intracellular Tenofovir Diphosphate and Emtricitabine Triphosphate Pharmacokinetics following Drug Intake Cessation.

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🔗 View Article (PMID 26195515)

Published in Antimicrob Agents Chemother on July 20, 2015

Authors

Laura Dickinson1, H Manisha Yapa2, Akil Jackson3, Graeme Moyle2, Laura Else4, Alieu Amara4, Saye Khoo4, David Back4, Zeenat Karolia2, Chris Higgs2, Marta Boffito2

Author Affiliations

1: Department of Molecular & Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom laurad@liv.ac.uk.
2: St Stephen's Centre, Chelsea & Westminster Foundation Trust, London, United Kingdom.
3: Department of Molecular & Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom St Stephen's Centre, Chelsea & Westminster Foundation Trust, London, United Kingdom.
4: Department of Molecular & Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom.

Associated clinical trials:

Phase II Safety and Acceptability of an Investigational Injectable Product, TMC278LA, for Pre-Exposure Prophylaxis (TMC278LA) | NCT02165202

A Study to Evaluate Safety, Acceptability, Pharmacokinetics, and ex Vivo Pharmacodynamics of TMC278 Long Acting Formulation in HIV-1 Seronegative Participants | NCT01656018

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