Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon.

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🔗 View Article (PMID 26216954)

Published in Proc Natl Acad Sci U S A on July 27, 2015

Authors

Noortje Ijssennagger1, Clara Belzer2, Guido J Hooiveld3, Jan Dekker4, Saskia W C van Mil5, Michael Müller6, Michiel Kleerebezem7, Roelof van der Meer6

Author Affiliations

1: Top Institute Food and Nutrition, 6709 PA, Wageningen, The Netherlands; Nutrition, Metabolism & Genomics Group, Division of Human Nutrition, Wageningen University, 6703 HD, Wageningen, The Netherlands; Department of Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, 3508 AB, Utrecht, The Netherlands; n.ijssennagger@umcutrecht.nl.
2: Top Institute Food and Nutrition, 6709 PA, Wageningen, The Netherlands; Laboratory of Microbiology, Wageningen University, 6703 HB, Wageningen, The Netherlands;
3: Nutrition, Metabolism & Genomics Group, Division of Human Nutrition, Wageningen University, 6703 HD, Wageningen, The Netherlands;
4: Top Institute Food and Nutrition, 6709 PA, Wageningen, The Netherlands; Host Microbe Interactomics Group, Animal Science Department, 6700 AH, Wageningen, The Netherlands;
5: Department of Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, 3508 AB, Utrecht, The Netherlands;
6: Top Institute Food and Nutrition, 6709 PA, Wageningen, The Netherlands; Nutrition, Metabolism & Genomics Group, Division of Human Nutrition, Wageningen University, 6703 HD, Wageningen, The Netherlands;
7: Top Institute Food and Nutrition, 6709 PA, Wageningen, The Netherlands; Host Microbe Interactomics Group, Animal Science Department, 6700 AH, Wageningen, The Netherlands; Health Department, NIZO Food Research, 6710 BA, Ede, The Netherlands.

Associated clinical trials:

SCD vs. Mediterranean Diet Therapy in Ulcerative Colitis | NCT04398550

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