Published in J Biol Chem on August 24, 2015
MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17
Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem (1987) 59.79
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science (2004) 19.19
Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev (2006) 15.20
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest (2005) 9.09
Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase. Biochem Biophys Res Commun (1986) 7.96
Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. J Biol Chem (1993) 7.16
Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proc Natl Acad Sci U S A (2003) 6.46
The role of iron regulatory proteins in mammalian iron homeostasis and disease. Nat Chem Biol (2006) 5.33
A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression. Cell Metab (2005) 4.79
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J (2004) 4.45
Interleukin-6 induces hepcidin expression through STAT3. Blood (2006) 4.24
MicroRNAs in metabolism and metabolic disorders. Nat Rev Mol Cell Biol (2012) 3.78
A position statement on NAFLD/NASH based on the EASL 2009 special conference. J Hepatol (2010) 3.53
STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation. Blood (2006) 3.38
Nonalcoholic fatty liver disease: pathology and pathogenesis. Annu Rev Pathol (2010) 3.36
Regulation of cytoplasmic mRNA decay. Nat Rev Genet (2012) 3.30
Increased adipose tissue expression of hepcidin in severe obesity is independent from diabetes and NASH. Gastroenterology (2006) 3.09
Alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression. J Biol Chem (2006) 2.90
Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes. J Gastroenterol Hepatol (2009) 2.75
Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet (2014) 2.70
The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice. J Clin Invest (2011) 2.30
C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism. J Biol Chem (2002) 2.16
HFE genotype, parenchymal iron accumulation, and liver fibrosis in patients with nonalcoholic fatty liver disease. Gastroenterology (2009) 2.07
Relationship between the pattern of hepatic iron deposition and histological severity in nonalcoholic fatty liver disease. Hepatology (2010) 1.98
Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2. Mol Biol Cell (2007) 1.89
Signalling pathways regulating nucleo-cytoplasmic shuttling of the mRNA-binding protein HuR. Cell Signal (2008) 1.84
Lipid metabolism and liver inflammation. I. Hepatic fatty acid uptake: possible role in steatosis. Am J Physiol Gastrointest Liver Physiol (2006) 1.80
Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA. Mol Cell Biol (2008) 1.75
Huh-7: a human "hemochromatotic" cell line. Hepatology (2010) 1.51
MicroRNA-214 is aberrantly expressed in cervical cancers and inhibits the growth of HeLa cells. IUBMB Life (2009) 1.46
The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase. Cancer Res (2009) 1.41
Protein kinase C delta activation and translocation to the nucleus are required for fatty acid-induced apoptosis of insulin-secreting cells. Diabetes (2003) 1.39
Pathways underlying iron accumulation in human nonalcoholic fatty liver disease. Am J Clin Nutr (2008) 1.25
Induction of autophagy by palmitic acid via protein kinase C-mediated signaling pathway independent of mTOR (mammalian target of rapamycin). J Biol Chem (2012) 1.19
Messenger RNA half-life measurements in mammalian cells. Methods Enzymol (2008) 1.11
HuR posttranscriptionally regulates WEE1: implications for the DNA damage response in pancreatic cancer cells. Cancer Res (2014) 1.05
Segmentation and quantification of subcellular structures in fluorescence microscopy images using Squassh. Nat Protoc (2014) 1.02
Ca2+-dependent protein kinase C isoforms induce cholestasis in rat liver. J Biol Chem (2003) 0.99
Palmitate induces insulin resistance without significant intracellular triglyceride accumulation in HepG2 cells. Metabolism (2009) 0.93
Lower serum hepcidin and greater parenchymal iron in nonalcoholic fatty liver disease patients with C282Y HFE mutations. Hepatology (2012) 0.93
Iron metabolism in Nonalcoholic Fatty Liver Disease. Curr Gastroenterol Rep (2012) 0.90
PKC{delta} is activated in a dietary model of steatohepatitis and regulates endoplasmic reticulum stress and cell death. J Biol Chem (2010) 0.90
Mechanism of lipid induced insulin resistance: activated PKCε is a key regulator. Biochim Biophys Acta (2011) 0.86
Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis. Mol Biol Cell (2011) 0.83
Identification of palmitate-regulated genes in HepG2 cells by applying microarray analysis. Biochim Biophys Acta (2007) 0.83
Lipid metabolism, oxidative stress and cell death are regulated by PKC delta in a dietary model of nonalcoholic steatohepatitis. PLoS One (2014) 0.83
MicroRNA-130a is up-regulated in mouse liver by iron deficiency and targets the bone morphogenetic protein (BMP) receptor ALK2 to attenuate BMP signaling and hepcidin transcription. J Biol Chem (2014) 0.81