2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC).

PubWeight™: 5.15‹?› | Rank: Top 1%

🔗 View Article (PMID 26320110)

Published in Eur Heart J on August 29, 2015

Authors

Marco Roffi1, Carlo Patrono1, Jean-Philippe Collet, Christian Mueller, Marco Valgimigli, Felicita Andreotti, Jeroen J Bax, Michael A Borger, Carlos Brotons, Derek P Chew, Baris Gencer, Gerd Hasenfuss, Keld Kjeldsen, Patrizio Lancellotti, Ulf Landmesser, Julinda Mehilli, Debabrata Mukherjee, Robert F Storey, Stephan Windecker, Helmut Baumgartner2, Oliver Gaemperli2, Stephan Achenbach2, Stefan Agewall2, Lina Badimon2, Colin Baigent2, Héctor Bueno2, Raffaele Bugiardini2, Scipione Carerj2, Filip Casselman2, Thomas Cuisset2, Çetin Erol2, Donna Fitzsimons2, Martin Halle2, Christian Hamm2, David Hildick-Smith2, Kurt Huber2, Efstathios Iliodromitis2, Stefan James2, Basil S Lewis2, Gregory Y H Lip2, Massimo F Piepoli2, Dimitrios Richter2, Thomas Rosemann2, Udo Sechtem2, Ph Gabriel Steg2, Christian Vrints2, Jose Luis Zamorano2, Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology

Author Affiliations

1: Marco.Roffi@hcuge.ch.
2: The disclosure forms of all experts involved in the development of these guidelines are available on the ESC website http://www.escardio.org/guidelines.

Associated clinical trials:

WilL LOWer Dose Aspirin be More Effective Following ACS? (WILLOW - ACS) (WILLOW ACS) | NCT02741817

Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen (MASTER DAPT) | NCT03023020

MGuard Stent and Microcirculation (GUARDIANCORY) | NCT03087175

Multimodality Investigation of Intermediate Culprit Lesion With Negative FFR in NSTE-ACS (SHERLOCK) | NCT03205514

Anti-platelet Effect of Berberine in Patients After Elective Percutaneous Coronary Intervention (APLABE-PCI) | NCT03378934

Optimized Antithrombotic Therapy of Acute Myocardial Infarction With Left Ventricular Mural Thrombus (OATH-AMI) | NCT03415386

Trial of Cardiac CT in Acute Chest Patients With Intermediate Level Initial High-sensitivity Cardiac Troponin (PROTECCT) | NCT03583320

Rapid Use of High-sensitive Cardiac Troponin I for ruling-in and Ruling-out of Acute Myocardial Infarction (RACING-MI) | NCT03634384

The Impact of Aspirin Dose Modification on the Innate Immune Response - Will Lower Dose Aspirin Therapy Reduce the Response to Endotoxin (WILLOW TREE) | NCT03869268

Impact of Stress CT Myocardial Perfusion on Downstream Resources and Prognosis (CTP-PRO) | NCT03976921

Coronary Angiography in Critically Ill Patients With Type II Myocardial Infarction | NCT04043091

Early Cardiac Magnetic Resonance Imaging in Suspected Non-ST-Elevation Myocardial Infarction (CMR-OBSERVE) | NCT04140019

Articles citing this

(truncated to the top 100)

The Treatment of Disorders of Lipid Metabolism. Dtsch Arztebl Int (2016) 2.91

The Interdisciplinary Management of Acute Chest Pain. Dtsch Arztebl Int (2015) 1.44

Synergistic Inhibition of Both P2Y1 and P2Y12 Adenosine Diphosphate Receptors As Novel Approach to Rapidly Attenuate Platelet-Mediated Thrombosis. Arterioscler Thromb Vasc Biol (2016) 1.39

Misleading high-sensitivity troponin algorithm for NSTEMI in the ESC guidelines. Clin Chem Lab Med (2015) 1.20

Diagnostic algorithms for acute coronary syndrome-is one better than another? Ann Transl Med (2016) 1.04

Comparison of the Efficacy and Safety of Early Rule Out Pathways for Acute Myocardial Infarction. Circulation (2016) 0.85

Role of cardiovascular magnetic resonance in the guidelines of the European Society of Cardiology. J Cardiovasc Magn Reson (2016) 0.83

The Differential Diagnosis of Dyspnea. Dtsch Arztebl Int (2016) 0.79

Evolution of Myocardial Infarction and its Biomarkers: A Historical Perspective. Heart Views (2017) 0.79

2015 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: comments from the Dutch ACS working group. Neth Heart J (2016) 0.79

Predictors and clinical implication of high-sensitivity cardiac troponin-I elevation following diagnostic cardiac catheterisations. Open Heart (2017) 0.78

Early Invasive Strategy and In-Hospital Survival Among Diabetics With Non-ST-Elevation Acute Coronary Syndromes: A Contemporary National Insight. J Am Heart Assoc (2017) 0.78

The development and application of a high-sensitivity immunoassay for cardiac myosin-binding protein C. Transl Res (2015) 0.78

Canada acute coronary syndrome score was a stronger baseline predictor than age ≥75 years of in-hospital mortality in acute coronary syndrome patients in western Romania. Clin Interv Aging (2016) 0.78

Statin-centric versus low-density lipoprotein-centric approach for atherosclerotic cardiovascular disease prevention: a Singapore perspective. Singapore Med J (2016) 0.78

International patterns of dual antiplatelet therapy duration after acute coronary syndromes. Heart (2016) 0.78

Assessment and classification of patients with myocardial injury and infarction in clinical practice. Heart (2016) 0.78

Mortality and morbidity trends after the first year in survivors of acute myocardial infarction: a systematic review. BMC Cardiovasc Disord (2017) 0.77

Early diagnosis of acute myocardial infarction in patients with mild elevations of cardiac troponin. Clin Res Cardiol (2017) 0.77

High-sensitivity cardiac troponin testing in routine practice: economic and organizational advantages. Ann Transl Med (2016) 0.77

Effects of cardiac telerehabilitation in patients with coronary artery disease using a personalised patient-centred web application: protocol for the SmartCare-CAD randomised controlled trial. BMC Cardiovasc Disord (2017) 0.77

Cardiopulmonary laboratory biomarkers in the evaluation of acute dyspnea. Open Access Emerg Med (2016) 0.77

Roles of High-Density Lipoprotein Cholesterol in Patients With Acute Myocardial Infarction. Medicine (Baltimore) (2016) 0.77

Interventional therapies in acute myocardial infarction complicated by cardiogenic shock. Herz (2016) 0.77

Vascular Disease in Young Indians (20-40 years): Role of Ischemic Heart Disease. J Clin Diagn Res (2016) 0.76

Reproducibility of coronary atherosclerotic plaque characteristics in populations with low, intermediate, and high prevalence of coronary artery disease by multidetector computer tomography: a guide to reliable visual coronary plaque assessments. Int J Cardiovasc Imaging (2016) 0.76

High-sensitivity cardiac troponin I assays in the diagnosis of acute myocardial infarction. Heart Asia (2017) 0.76

Severe Rhabdomyolysis due to Presumed Drug Interactions between Atorvastatin with Amlodipine and Ticagrelor. Case Rep Crit Care (2017) 0.75

Two-year outcome after early or late Intervention in non-ST elevation acute coronary syndrome. Open Heart (2017) 0.75

Platelet aggregation and risk of stent thrombosis or bleeding in interventionally treated diabetic patients with acute coronary syndrome. BMC Cardiovasc Disord (2016) 0.75

Elevated high-sensitive troponin T on admission is an indicator of poor long-term outcome in patients with subarachnoid haemorrhage: a prospective observational study. Crit Care (2016) 0.75

In vivo MRI and ex vivo histological assessment of the cardioprotection induced by ischemic preconditioning, postconditioning and remote conditioning in a closed-chest porcine model of reperfused acute myocardial infarction: importance of microvasculature. J Transl Med (2017) 0.75

Invasive coronary angiography in patients with acute exacerbated COPD and elevated plasma troponin. Int J Chron Obstruct Pulmon Dis (2016) 0.75

Indications, algorithms, and outcomes for coronary artery bypass surgery in patients with acute coronary syndromes. Coron Artery Dis (2016) 0.75

Asia-Pacific consensus statement on the optimal use of high-sensitivity troponin assays in acute coronary syndromes diagnosis: focus on hs-TnI. Heart Asia (2017) 0.75

Is there a role for a local inpatient CT coronary angiography service in selected patients with acute coronary syndrome? A cohort analysis of inpatient tertiary centre referrals for invasive coronary angiography. Open Heart (2016) 0.75

Selecting patients with non-ST-elevation acute coronary syndrome for coronary angiography: a nationwide clinical vignette study in the Netherlands. BMJ Open (2017) 0.75

Study to Improve Cardiovascular Outcomes in high-risk older patieNts (ICON1) with acute coronary syndrome: study design and protocol of a prospective observational study. BMJ Open (2016) 0.75

Invasive management of acute coronary syndromes. Lancet (2016) 0.75

Staged versus "one-time" multivessel intervention in elderly patients with non-ST-elevation acute coronary syndrome. J Geriatr Cardiol (2016) 0.75

Relationship between ADP-induced platelet-fibrin clot strength and anti-platelet responsiveness in ticagrelor treated ACS patients. J Geriatr Cardiol (2016) 0.75

MicroRNAs in Coronary Heart Disease: Ready to Enter the Clinical Arena? Biomed Res Int (2016) 0.75

Identification of High-Risk Patients with Non-ST Segment Elevation Myocardial Infarction using Strain Doppler Echocardiography: Correlation with Cardiac Magnetic Resonance Imaging. Clin Med Insights Cardiol (2016) 0.75

Prognostic Value of Cardiac Troponin T and Sex in Patients Undergoing Elective Percutaneous Coronary Intervention. J Am Heart Assoc (2016) 0.75

Antithrombotic therapy for patients with STEMI undergoing primary PCI. Nat Rev Cardiol (2017) 0.75

Antithrombotic management in patients with percutaneous coronary intervention requiring oral anticoagulation. Postepy Kardiol Interwencyjnej (2016) 0.75

Single or dual antiplatelet therapy after PCI. Nat Rev Cardiol (2017) 0.75

Management of patients with chest pain presenting to the emergency department: in need for the implementation of the 1 h rapid rule-out algorithm using high-sensitivity troponin I assays in clinical practice. Ann Transl Med (2016) 0.75

Long-term clinical outcomes of patients with rheumatoid arthritis and concomitant coronary artery disease. Am J Cardiovasc Dis (2017) 0.75

High Sensitivity Cardiac Troponin Assays - How to Implement them Successfully. EJIFCC (2016) 0.75

Relationship of Platelet Reactivity With Bleeding Outcomes During Long-Term Treatment With Dual Antiplatelet Therapy for Medically Managed Patients With Non-ST-Segment Elevation Acute Coronary Syndromes. J Am Heart Assoc (2016) 0.75

Antithrombotic therapy for secondary prevention of atherothrombotic events in cerebrovascular disease. Nat Rev Cardiol (2016) 0.75

Cardiac biomarkers of acute coronary syndrome: from history to high-sensitivity cardiac troponin. Intern Emerg Med (2017) 0.75

Early diagnosis of acute myocardial infarction using high-sensitivity troponin I. PLoS One (2017) 0.75

Impact of high-sensitivity cardiac troponin on use of coronary angiography, cardiac stress testing, and time to discharge in suspected acute myocardial infarction. Eur Heart J (2016) 0.75

Factors associated with unattained LDL-cholesterol goals in Chinese patients with acute coronary syndrome one year after percutaneous coronary intervention. Medicine (Baltimore) (2017) 0.75

Chest pain: coronary CT in the ER. Br J Radiol (2016) 0.75

Personalising the decision for prolonged dual antiplatelet therapy: development, validation and potential impact of prognostic models for cardiovascular events and bleeding in myocardial infarction survivors. Eur Heart J (2017) 0.75

Prognostic value of ejection fraction in patients admitted with acute coronary syndrome: A real world study. Medicine (Baltimore) (2017) 0.75

III SBC Guidelines on the Analysis and Issuance of Electrocardiographic Reports - Executive Summary. Arq Bras Cardiol (2016) 0.75

Impact of concomitant use of proton pump inhibitors and clopidogrel or ticagrelor on clinical outcomes in patients with acute coronary syndrome. J Geriatr Cardiol (2016) 0.75

Stroke Prevention in Atrial Fibrillation: A Clinical Perspective on Trials of the Novel Oral Anticoagulants. Cardiovasc Drugs Ther (2016) 0.75

Clinical utility of novel biomarkers in acute myocardial infarction. Ann Transl Med (2016) 0.75

Providing Rapid Out of Hospital Acute Cardiovascular Treatment 4 (PROACT-4). J Am Heart Assoc (2015) 0.75

Prognostic value of basal high-sensitive cardiac troponin levels on mortality in the general population: A meta-analysis. Medicine (Baltimore) (2016) 0.75

Anemia and Acute Coronary Syndrome: Time for Intervention Studies. J Am Heart Assoc (2016) 0.75

Post resuscitation care - some words of caution and a call for action. Scand J Trauma Resusc Emerg Med (2015) 0.75

Neurohormonal Activation After Atrial Fibrillation Initiation in Patients Eligible for Catheter Ablation: A Randomized Controlled Study. J Am Heart Assoc (2016) 0.75

Differential Impact of Hyperglycemia in Critically Ill Patients: Significance in Acute Myocardial Infarction but Not in Sepsis? Int J Mol Sci (2016) 0.75

Circulating micro ribonucleic acids in cardiovascular disease: a look beyond myocardial injury. Ann Transl Med (2016) 0.75

The RAPID-CTCA trial (Rapid Assessment of Potential Ischaemic Heart Disease with CTCA) - a multicentre parallel-group randomised trial to compare early computerised tomography coronary angiography versus standard care in patients presenting with suspected or confirmed acute coronary syndrome: study protocol for a randomised controlled trial. Trials (2016) 0.75

Triple anticoagulation therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention - real life assessment. Postepy Kardiol Interwencyjnej (2016) 0.75

Antithrombotic agents for secondary prevention after acute coronary syndromes: A systematic review and network meta-analysis. Int J Cardiol (2017) 0.75

In Reply. Dtsch Arztebl Int (2016) 0.75

P2Y12 Inhibitor Pre-Treatment in Non-ST-Elevation Acute Coronary Syndrome: A Decision-Analytic Model. J Clin Med (2016) 0.75

Does heart rate variability correlate with long-term prognosis in myocardial infarction patients treated by early revascularization? World J Cardiol (2017) 0.75

High-density lipoprotein cholesterol values independently and inversely predict cardiac troponin T and I concentration. Ann Transl Med (2016) 0.75

Design and reliability of a specific instrument to evaluate patient safety for patients with acute myocardial infarction treated in a predefined care track: a retrospective patient record review study in a single tertiary hospital in the Netherlands. BMJ Open (2017) 0.75

Geographic variation in the treatment of non-ST-segment myocardial infarction in the English National Health Service: a cohort study. BMJ Open (2016) 0.75

Pharmacotherapy: Current role of β-blockers after MI in patients without HF. Nat Rev Cardiol (2016) 0.75

Adherence to Cardiac Practice Guidelines in the Management of Non-ST-Elevation Acute Coronary Syndromes: A Systematic Literature Review. Curr Cardiol Rev (2017) 0.75

Type 2 Diabetes and ADP Receptor Blocker Therapy. J Diabetes Res (2015) 0.75

Ischemic Left Ventricular Perforation Covered by a Thrombus in a Patient Presenting with Cerebral Ischemia: Importance of Time-Sensitive Performance and Adequate Interpretation of Bedside Transthoracic Echography. Case Rep Emerg Med (2016) 0.75

Expert position paper on prolonged dual antiplatelet therapy in secondary prevention following myocardial infarction. Wien Klin Wochenschr (2016) 0.75

Fondaparinux versus Enoxaparin - Which is the Best Anticoagulant for Acute Coronary Syndrome? - Brazilian Registry Data. Arq Bras Cardiol (2016) 0.75

Predictive value of NT-proBNP for 30-day mortality in patients with non-ST-elevation acute coronary syndromes: a comparison with the GRACE and TIMI risk scores. Vasc Health Risk Manag (2016) 0.75

Early Discharge in Low-Risk Patients Hospitalized for Acute Coronary Syndromes: Feasibility, Safety and Reasons for Prolonged Length of Stay. PLoS One (2016) 0.75

"One-Time" versus Staged Multivessel Intervention in Intermediate to Very High-Risk Patients with Non-ST-Segment Elevation Acute Coronary Syndromes. Korean Circ J (2016) 0.75

Time to shift from contemporary to high-sensitivity cardiac troponin in diagnosis of acute coronary syndromes. Indian Heart J (2016) 0.75

Impact of low high-density lipoprotein-cholesterol level on 2-year clinical outcomes after acute myocardial infarction in patients with diabetes mellitus. Lipids Health Dis (2016) 0.75

Preprocedural C-Reactive Protein Predicts Outcomes after Primary Percutaneous Coronary Intervention in Patients with ST-elevation Myocardial Infarction a systematic meta-analysis. Sci Rep (2017) 0.75

Predictive values of D-dimer assay, GRACE scores and TIMI scores for adverse outcome in patients with non-ST-segment elevation myocardial infarction. Ther Clin Risk Manag (2017) 0.75

High adherence to therapy and low cardiac mortality and morbidity in patients after acute coronary syndrome systematically managed by office-based cardiologists in Germany: 1-year outcomes of the ProAcor Study. Vasc Health Risk Manag (2017) 0.75

Comparison of Electric- and Magnetic-Cardiograms Produced by Myocardial Ischemia in Models of the Human Ventricle and Torso. PLoS One (2016) 0.75

Postprocedural radial artery occlusion rate using a sheathless guiding catheter for left ventricular endomyocardial biopsy performed by transradial approach. BMC Cardiovasc Disord (2016) 0.75

Ticagrelor induced systemic inflammatory response syndrome. BMC Cardiovasc Disord (2017) 0.75

Impact of betablockers on general and local outcome in patients hospitalized for lower extremity peripheral artery disease: The COPART Registry. Medicine (Baltimore) (2017) 0.75

Screening Characteristics of TIMI Score in Predicting Acute Coronary Syndrome Outcome; a Diagnostic Accuracy Study. Emerg (Tehran) (2017) 0.75

When is the Best Time for the Second Antiplatelet Agent in Non-St Elevation Acute Coronary Syndrome? Arq Bras Cardiol (2016) 0.75

Establishment of a hybrid risk model to predict major cardiac adverse events in patients with non-ST-elevation acute coronary syndromes. Exp Ther Med (2016) 0.75

Articles by these authors

ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J (2012) 18.18

Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med (2009) 18.03

ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J (2011) 13.10

2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J (2013) 12.73

Universal definition of myocardial infarction. Circulation (2007) 11.69

Guidelines on the management of valvular heart disease (version 2012). Eur Heart J (2012) 10.70

ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Eur Heart J (2011) 10.52

ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail (2012) 10.38

Clinical end points in coronary stent trials: a case for standardized definitions. Circulation (2007) 10.31

2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J (2014) 9.73

2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J (2013) 9.54

Long-term use of ticagrelor in patients with prior myocardial infarction. N Engl J Med (2015) 8.69

Third universal definition of myocardial infarction. J Am Coll Cardiol (2012) 8.59

European guidelines on cardiovascular disease prevention in clinical practice. Third Joint Task Force of European and Other Societies on Cardiovascular Disease Prevention in Clinical Practice. Eur Heart J (2003) 8.51

Third universal definition of myocardial infarction. Circulation (2012) 8.47

Early diagnosis of myocardial infarction with sensitive cardiac troponin assays. N Engl J Med (2009) 8.05

Third universal definition of myocardial infarction. Eur Heart J (2012) 7.98

Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study. Lancet (2007) 7.61

Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study. J Am Coll Cardiol (2008) 7.56

Cardiac-resynchronization therapy in heart failure with a narrow QRS complex. N Engl J Med (2013) 7.35

Results of the Predictors of Response to CRT (PROSPECT) trial. Circulation (2008) 7.11

Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis. Lancet (2007) 6.77

Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the Bleeding Academic Research Consortium. Circulation (2011) 6.36

2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions. J Am Coll Cardiol (2011) 6.35

Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis. JAMA (2010) 6.29

2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: the Task Force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). Developed in collaboration with the European Heart Rhythm Association (EHRA). Eur Heart J (2013) 6.17

Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: an observational study of drug-eluting versus bare-metal stents. J Am Coll Cardiol (2006) 6.07

Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy. N Engl J Med (2015) 6.00

A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy. Cell (2007) 5.85

ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. Circulation (2009) 5.49

Guidelines on the management of valvular heart disease (version 2012): the Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur J Cardiothorac Surg (2012) 5.49

Effect of spironolactone on diastolic function and exercise capacity in patients with heart failure with preserved ejection fraction: the Aldo-DHF randomized controlled trial. JAMA (2013) 5.41

Fluvastatin and perioperative events in patients undergoing vascular surgery. N Engl J Med (2009) 5.26

Prehospital ticagrelor in ST-segment elevation myocardial infarction. N Engl J Med (2014) 5.25

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). Eur Heart J (2015) 5.24

ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: the Task Force on diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and developed in collaboration with the European Association for the Study of Diabetes (EASD). Eur Heart J (2013) 5.23

2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC). Eur Heart J (2014) 5.21

2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions. Circulation (2011) 5.09

Association of blood transfusion with increased mortality in myocardial infarction: a meta-analysis and diversity-adjusted study sequential analysis. JAMA Intern Med (2013) 5.02

Prospective randomized study of doxorubicin-eluting-bead embolization in the treatment of hepatocellular carcinoma: results of the PRECISION V study. Cardiovasc Intervent Radiol (2009) 4.82

Procalcitonin usefulness for the initiation of antibiotic treatment in intensive care unit patients. Crit Care Med (2012) 4.76

Percutaneous closure of patent foramen ovale in cryptogenic embolism. N Engl J Med (2013) 4.62

2014 AHA/ACC Guideline for the Management of Patients with Non-ST-Elevation Acute Coronary Syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2014) 4.57

ESC Guidelines on the diagnosis and treatment of peripheral artery diseases: Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries: the Task Force on the Diagnosis and Treatment of Peripheral Artery Diseases of the European Society of Cardiology (ESC). Eur Heart J (2011) 4.47

Relationship between noninvasive coronary angiography with multi-slice computed tomography and myocardial perfusion imaging. J Am Coll Cardiol (2006) 4.37

Compliance with QUOROM and quality of reporting of overlapping meta-analyses on the role of acetylcysteine in the prevention of contrast associated nephropathy: case study. BMJ (2006) 4.36

Lipoprotein(a) as a cardiovascular risk factor: current status. Eur Heart J (2010) 4.31

Pluripotency of spermatogonial stem cells from adult mouse testis. Nature (2006) 4.29

One-hour rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T. Arch Intern Med (2012) 4.24

Abciximab in patients with acute coronary syndromes undergoing percutaneous coronary intervention after clopidogrel pretreatment: the ISAR-REACT 2 randomized trial. JAMA (2006) 4.18

Sirolimus-eluting stents associated with paradoxic coronary vasoconstriction. J Am Coll Cardiol (2005) 4.05

Risk of late aortic events after an isolated aortic valve replacement for bicuspid aortic valve stenosis with concomitant ascending aortic dilation. Eur J Cardiothorac Surg (2012) 4.05

Esophageal perforation during left atrial radiofrequency ablation: Is the risk too high? J Thorac Cardiovasc Surg (2003) 4.03

Percutaneous coronary intervention with everolimus-eluting bioresorbable vascular scaffolds in routine clinical practice: early and midterm outcomes from the European multicentre GHOST-EU registry. EuroIntervention (2015) 4.00

Lipid treatment assessment project 2: a multinational survey to evaluate the proportion of patients achieving low-density lipoprotein cholesterol goals. Circulation (2009) 3.98

Analysis of 14 trials comparing sirolimus-eluting stents with bare-metal stents. N Engl J Med (2007) 3.84

Stem cell mobilization by granulocyte colony-stimulating factor in patients with acute myocardial infarction: a randomized controlled trial. JAMA (2006) 3.78

Paclitaxel-eluting or sirolimus-eluting stents to prevent restenosis in diabetic patients. N Engl J Med (2005) 3.75

Increased myocardial NADPH oxidase activity in human heart failure. J Am Coll Cardiol (2003) 3.73

Utility of absolute and relative changes in cardiac troponin concentrations in the early diagnosis of acute myocardial infarction. Circulation (2011) 3.72

2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: The Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC)Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC). Eur Heart J (2015) 3.70

Mechanical reperfusion in patients with acute myocardial infarction presenting more than 12 hours from symptom onset: a randomized controlled trial. JAMA (2005) 3.67