Published in Cell Microbiol on November 10, 2015
Rapid Generation of Marker-Free P. falciparum Fluorescent Reporter Lines Using Modified CRISPR/Cas9 Constructs and Selection Protocol. PLoS One (2016) 0.78
Protective Efficacy Induced by Genetically Attenuated Mid-to-Late Liver-Stage Arresting Plasmodium berghei Δmrp2 Parasites. Am J Trop Med Hyg (2016) 0.75
Phylogenetic profiles of all membrane transport proteins. Microb Cell (2016) 0.75
Protective efficacy and safety of liver stage attenuated malaria parasites. Sci Rep (2016) 0.75
Mammalian ABC transporters in health and disease. Annu Rev Biochem (2001) 4.90
Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity. Science (2011) 4.72
Manipulation of host hepatocytes by the malaria parasite for delivery into liver sinusoids. Science (2006) 4.20
High-efficiency transfection and drug selection of genetically transformed blood stages of the rodent malaria parasite Plasmodium berghei. Nat Protoc (2006) 4.19
A family of drug transporters: the multidrug resistance-associated proteins. J Natl Cancer Inst (2000) 3.98
Multiple molecular mechanisms for multidrug resistance transporters. Nature (2007) 3.96
High efficiency transfection of Plasmodium berghei facilitates novel selection procedures. Mol Biochem Parasitol (2005) 3.95
Complete in vitro maturation of Plasmodium falciparum gametocytes. Nature (1981) 3.88
Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine. Proc Natl Acad Sci U S A (1996) 3.86
Multiple transporters associated with malaria parasite responses to chloroquine and quinine. Mol Microbiol (2003) 3.26
Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface. Proc Natl Acad Sci U S A (2005) 3.06
Antibodies inhibit the protease-mediated processing of a malaria merozoite surface protein. J Exp Med (1994) 2.94
Cloning of naturally occurring mixed infections of malaria parasites. Science (1981) 2.84
Negative selection of Plasmodium falciparum reveals targeted gene deletion by double crossover recombination. Int J Parasitol (2002) 2.70
Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum. Mol Microbiol (2000) 2.62
Targeting Plasmodium PI(4)K to eliminate malaria. Nature (2013) 2.49
Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells. Proc Natl Acad Sci U S A (2005) 2.49
Type II fatty acid synthesis is essential only for malaria parasite late liver stage development. Cell Microbiol (2008) 2.49
Infectivity of cultured Plasmodium falciparum gametocytes to mosquitoes. Parasitology (1989) 2.10
Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules. Trends Pharmacol Sci (2008) 1.88
Disruption of a Plasmodium falciparum multidrug resistance-associated protein (PfMRP) alters its fitness and transport of antimalarial drugs and glutathione. J Biol Chem (2008) 1.86
Comparison of a SYBR green I-based assay with a histidine-rich protein II enzyme-linked immunosorbent assay for in vitro antimalarial drug efficacy testing and application to clinical isolates. Antimicrob Agents Chemother (2007) 1.85
Structural analysis of the glycosyl-phosphatidylinositol membrane anchor of the merozoite surface proteins-1 and -2 of Plasmodium falciparum. Mol Biochem Parasitol (1996) 1.80
Synchronization of Plasmodium falciparum gametocytes using an automated suspension culture system. Parasitology (1986) 1.78
Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development. Curr Med Chem (2008) 1.78
Cultivation of fertile Plasmodium falciparum gametocytes in semi-automated systems. 1. Static cultures. Trans R Soc Trop Med Hyg (1982) 1.71
ABC transporters: a riddle wrapped in a mystery inside an enigma. Trends Biochem Sci (2009) 1.69
Structure and function of efflux pumps that confer resistance to drugs. Biochem J (2003) 1.66
Host cell phosphatidylcholine is a key mediator of malaria parasite survival during liver stage infection. Cell Host Microbe (2014) 1.66
A sporozoite asparagine-rich protein controls initiation of Plasmodium liver stage development. PLoS Pathog (2008) 1.65
Plasmodium berghei: the application of cultivation and purification techniques to molecular studies of malaria parasites. Parasitol Today (1995) 1.61
Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites. Cell Host Microbe (2011) 1.61
Malaria sporozoites leave behind trails of circumsporozoite protein during gliding motility. J Protozool (1988) 1.58
Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection. Mol Microbiol (2008) 1.56
Dissecting in vitro host cell infection by Plasmodium sporozoites using flow cytometry. Cell Microbiol (2007) 1.50
A malaria heat-shock-like determinant expressed on the infected hepatocyte surface is the target of antibody-dependent cell-mediated cytotoxic mechanisms by nonparenchymal liver cells. Eur J Immunol (1990) 1.35
Functional equivalence of structurally distinct ribosomes in the malaria parasite, Plasmodium berghei. J Biol Chem (2001) 1.34
Plasmodium falciparum multidrug resistance protein 1 and artemisinin-based combination therapy in Africa. J Infect Dis (2009) 1.26
Plasmepsin 4-deficient Plasmodium berghei are virulence attenuated and induce protective immunity against experimental malaria. Am J Pathol (2009) 1.26
Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes. PLoS One (2008) 1.25
Effects of irradiation on Plasmodium falciparum sporozoite hepatic development: implications for the design of pre-erythrocytic malaria vaccines. Parasite Immunol (2002) 1.23
Cellular export of drugs and signaling molecules by the ATP-binding cassette transporters MRP4 (ABCC4) and MRP5 (ABCC5). Drug Metab Rev (2005) 1.22
Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo. J Exp Med (2011) 1.20
High yield preparation of isolated human adult hepatocytes by enzymatic perfusion of the liver. Cell Biol Int Rep (1982) 1.18
An improved and highly sensitive microfluorimetric method for assessing susceptibility of Plasmodium falciparum to antimalarial drugs in vitro. Malar J (2006) 1.16
Role of Plasmodium berghei cGMP-dependent protein kinase in late liver stage development. J Biol Chem (2009) 1.13
Real-time PCR for chloroquine sensitivity assay and for pfmdr1-pfcrt single nucleotide polymorphisms in Plasmodium falciparum. J Microbiol Methods (2003) 1.12
Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates. Vaccine (2012) 1.11
Plasmodium falciparum expresses a multidrug resistance-associated protein. Biochem Biophys Res Commun (2004) 1.11
Mammalian multidrug-resistance proteins (MRPs). Essays Biochem (2011) 1.11
A novel artemisinin-quinine hybrid with potent antimalarial activity. Bioorg Med Chem Lett (2007) 1.10
Genetic engineering of attenuated malaria parasites for vaccination. Curr Opin Biotechnol (2012) 1.06
Live and let die: manipulation of host hepatocytes by exoerythrocytic Plasmodium parasites. Med Microbiol Immunol (2007) 1.05
Conserved protective mechanisms in radiation and genetically attenuated uis3(-) and uis4(-) Plasmodium sporozoites. PLoS One (2009) 1.04
Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development. FASEB J (2014) 1.04
SAP1 is a critical post-transcriptional regulator of infectivity in malaria parasite sporozoite stages. Mol Microbiol (2010) 1.04
The ABCs of multidrug resistance in malaria. Trends Parasitol (2010) 1.01
Transmission blockade of Plasmodium falciparum: its variability with gametocyte numbers and concentration of antibody. Trans R Soc Trop Med Hyg (1987) 1.01
Polymorphism in PfMRP1 (Plasmodium falciparum multidrug resistance protein 1) amino acid 1466 associated with resistance to sulfadoxine-pyrimethamine treatment. Antimicrob Agents Chemother (2009) 1.01
Liver or blood-stage arrest during malaria sporozoite immunization: the later the better? Trends Parasitol (2013) 1.00
Proteins on the surface of the malaria parasite and cell invasion. Parasitology (1994) 0.99
The biotin-streptavidin system in a two-site ELISA for the detection of plasmodial sporozoite antigen in mosquitoes. Parasite Immunol (1988) 0.98
Long-term live imaging reveals cytosolic immune responses of host hepatocytes against Plasmodium infection and parasite escape mechanisms. Autophagy (2015) 0.96
Evaluation of bioluminescence-based assays of anti-malarial drug activity. Malar J (2013) 0.93
Removal of heterologous sequences from Plasmodium falciparum mutants using FLPe-recombinase. PLoS One (2010) 0.90
A next-generation genetically attenuated Plasmodium falciparum parasite created by triple gene deletion. Mol Ther (2014) 0.89
Localization of the ATP-binding cassette (ABC) transport proteins PfMRP1, PfMRP2, and PfMDR5 at the Plasmodium falciparum plasma membrane. Malar J (2009) 0.87
Exploiting the therapeutic potential of Plasmodium falciparum solute transporters. Trends Parasitol (2010) 0.86
Feeling at home from arrival to departure: protein export and host cell remodelling during Plasmodium liver stage and gametocyte maturation. Cell Microbiol (2014) 0.86
Structural polymorphism in the promoter of pfmrp2 confers Plasmodium falciparum tolerance to quinoline drugs. Mol Microbiol (2014) 0.83
Antiprotozoal activity of chloroquinoline based chalcones. Eur J Med Chem (2011) 0.81
Identification and bioinformatic characterization of a multidrug resistance associated protein (ABCC) gene in Plasmodium berghei. Malar J (2009) 0.81
Complex polymorphisms in the Plasmodium falciparum multidrug resistance protein 2 gene and its contribution to antimalarial response. Antimicrob Agents Chemother (2014) 0.80
ATP and luciferase assays to determine the rate of drug action in in vitro cultures of Plasmodium falciparum. Malar J (2012) 0.78