Published in Diabetes on September 22, 2015
Look AHEAD: Action for Health in Diabetes (LookAHEAD) | NCT00017953
Gene x Behavior Interaction in the Look AHEAD Study | NCT01270763
Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids. Cardiovasc Diabetol (2016) 0.75
Progress in Defining the Genetic Basis of Diabetic Complications. Curr Diab Rep (2017) 0.75
Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 15.58
Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial. Diabetes Care (2007) 14.35
Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. Control Clin Trials (2003) 9.97
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet (2012) 6.15
Baseline characteristics of the randomised cohort from the Look AHEAD (Action for Health in Diabetes) study. Diab Vasc Dis Res (2006) 4.30
Modelling clustered survival data from multicentre clinical trials. Stat Med (2004) 3.02
The glial glutamate transporter 1 (GLT1) is expressed by pancreatic beta-cells and prevents glutamate-induced beta-cell death. J Biol Chem (2011) 1.72
Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes. JAMA (2013) 1.22
Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes. Diabetes (2015) 0.85
Effect of glutamine supplementation on cardiovascular risk factors in patients with type 2 diabetes. Nutrition (2014) 0.82
Prospective association of a genetic risk score and lifestyle intervention with cardiovascular morbidity and mortality among individuals with type 2 diabetes: the Look AHEAD randomised controlled trial. Diabetologia (2015) 0.80
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 15.58
Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. Control Clin Trials (2003) 9.97
Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes. Diabetes Care (2011) 5.50
Association of an intensive lifestyle intervention with remission of type 2 diabetes. JAMA (2012) 5.15
Effect of a long-term behavioural weight loss intervention on nephropathy in overweight or obese adults with type 2 diabetes: a secondary analysis of the Look AHEAD randomised clinical trial. Lancet Diabetes Endocrinol (2014) 4.30
One-year weight losses in the Look AHEAD study: factors associated with success. Obesity (Silver Spring) (2009) 4.08
Four-year weight losses in the Look AHEAD study: factors associated with long-term success. Obesity (Silver Spring) (2011) 3.62
Eight-year weight losses with an intensive lifestyle intervention: the look AHEAD study. Obesity (Silver Spring) (2014) 3.10
Lifestyle change and mobility in obese adults with type 2 diabetes. N Engl J Med (2012) 2.90
Impact of a weight management program on health-related quality of life in overweight adults with type 2 diabetes. Arch Intern Med (2009) 2.59
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
One-year changes in symptoms of depression and weight in overweight/obese individuals with type 2 diabetes in the Look AHEAD study. Obesity (Silver Spring) (2011) 1.97
Weight loss prevents urinary incontinence in women with type 2 diabetes: results from the Look AHEAD trial. J Urol (2012) 1.85
Do weight loss and adherence cluster within behavioral treatment groups? Obesity (Silver Spring) (2013) 1.83
Effectiveness of lifestyle interventions for individuals with severe obesity and type 2 diabetes: results from the Look AHEAD trial. Diabetes Care (2011) 1.78
Intensive lifestyle intervention improves physical function among obese adults with knee pain: findings from the Look AHEAD trial. Obesity (Silver Spring) (2010) 1.78
Suboptimal control of glycemia, blood pressure, and LDL cholesterol in overweight adults with diabetes: the Look AHEAD Study. J Diabetes Complications (2008) 1.77
Exercise capacity and cardiovascular/metabolic characteristics of overweight and obese individuals with type 2 diabetes: the Look AHEAD clinical trial. Diabetes Care (2007) 1.50
Evaluation of early weight loss thresholds for identifying nonresponders to an intensive lifestyle intervention. Obesity (Silver Spring) (2014) 1.44
Correlates of health-related quality of life in overweight and obese adults with type 2 diabetes. Obesity (Silver Spring) (2006) 1.43
Effect of the look AHEAD study intervention on medication use and related cost to treat cardiovascular disease risk factors in individuals with type 2 diabetes. Diabetes Care (2010) 1.39
Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: the action for health in diabetes. Diabetes Care (2014) 1.38
Action for Health in Diabetes (Look AHEAD) trial: baseline evaluation of selected nutrients and food group intake. J Am Diet Assoc (2009) 1.30
The long-term effectiveness of a lifestyle intervention in severely obese individuals. Am J Med (2013) 1.22
A 1-year lifestyle intervention for weight loss in individuals with type 2 diabetes reduces high C-reactive protein levels and identifies metabolic predictors of change: from the Look AHEAD (Action for Health in Diabetes) study. Diabetes Care (2010) 1.21
Impact of intensive lifestyle intervention on depression and health-related quality of life in type 2 diabetes: the Look AHEAD Trial. Diabetes Care (2014) 1.19
Obesity susceptibility loci and dietary intake in the Look AHEAD Trial. Am J Clin Nutr (2012) 1.18
Consent for genetics studies among clinical trial participants: findings from Action for Health in Diabetes (Look AHEAD). Clin Trials (2006) 1.15
Patterns of weight change associated with long-term weight change and cardiovascular disease risk factors in the Look AHEAD Study. Obesity (Silver Spring) (2012) 1.12
Altered body composition in type 2 diabetes mellitus. Int J Obes (Lond) (2008) 1.10
Neighborhood and weight-related health behaviors in the Look AHEAD (Action for Health in Diabetes) study. BMC Public Health (2010) 1.07
Four-year change in cardiorespiratory fitness and influence on glycemic control in adults with type 2 diabetes in a randomized trial: the Look AHEAD Trial. Diabetes Care (2012) 1.02
Lifestyle intervention improves heart rate recovery from exercise in adults with type 2 diabetes: results from the Look AHEAD study. J Obes (2012) 1.01
Effect of 1 year of an intentional weight loss intervention on bone mineral density in type 2 diabetes: results from the Look AHEAD randomized trial. J Bone Miner Res (2012) 1.01
Neighborhood socioeconomic status, depression, and health status in the Look AHEAD (Action for Health in Diabetes) study. BMC Public Health (2011) 1.00
Cardiovascular disease risk factors, depression symptoms and antidepressant medicine use in the Look AHEAD (Action for Health in Diabetes) clinical trial of weight loss in diabetes. Diabetologia (2010) 0.99
Long-term impact of behavioral weight loss intervention on cognitive function. J Gerontol A Biol Sci Med Sci (2014) 0.98
Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the Look AHEAD randomised clinical trial. Lancet Diabetes Endocrinol (2016) 0.98
Binge eating and weight loss outcomes in overweight and obese individuals with type 2 diabetes: results from the Look AHEAD trial. Arch Gen Psychiatry (2008) 0.96
Weight change in the first 2 months of a lifestyle intervention predicts weight changes 8 years later. Obesity (Silver Spring) (2015) 0.96
Changes in body composition over 8 years in a randomized trial of a lifestyle intervention: the look AHEAD study. Obesity (Silver Spring) (2015) 0.94
Adiponectin and the mediation of HDL-cholesterol change with improved lifestyle: the Look AHEAD Study. J Lipid Res (2012) 0.88
Factors influencing enrollment of African Americans in the Look AHEAD trial. Clin Trials (2011) 0.88
FTO predicts weight regain in the Look AHEAD clinical trial. Int J Obes (Lond) (2013) 0.88
Four-year analysis of cardiovascular disease risk factors, depression symptoms, and antidepressant medicine use in the Look AHEAD (Action for Health in Diabetes) clinical trial of weight loss in diabetes. Diabetes Care (2013) 0.85
Intensive lifestyle intervention reduces urinary incontinence in overweight/obese men with type 2 diabetes: results from the Look AHEAD trial. J Urol (2014) 0.85
Intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 0.84
Human cardiovascular disease IBC chip-wide association with weight loss and weight regain in the look AHEAD trial. Hum Hered (2013) 0.84
Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Hum Mol Genet (2013) 0.84
Aging and physical function in type 2 diabetes: 8 years of an intensive lifestyle intervention. J Gerontol A Biol Sci Med Sci (2014) 0.84
Prevalence and predictors of abnormal cardiovascular responses to exercise testing among individuals with type 2 diabetes: the Look AHEAD (Action for Health in Diabetes) study. Diabetes Care (2010) 0.82
Genetic modifiers of cardiorespiratory fitness response to lifestyle intervention. Med Sci Sports Exerc (2014) 0.81
Effect of an intensive lifestyle intervention on atrial fibrillation risk in individuals with type 2 diabetes: the Look AHEAD randomized trial. Am Heart J (2015) 0.81
Partial Meal Replacement Plan and Quality of the Diet at 1 Year: Action for Health in Diabetes (Look AHEAD) Trial. J Acad Nutr Diet (2015) 0.81
Prospective association of a genetic risk score and lifestyle intervention with cardiovascular morbidity and mortality among individuals with type 2 diabetes: the Look AHEAD randomised controlled trial. Diabetologia (2015) 0.80
Implications of Look AHEAD for clinical trials and clinical practice. Diabetes Obes Metab (2014) 0.80
Systolic Blood Pressure Control Among Individuals With Type 2 Diabetes: A Comparative Effectiveness Analysis of Three Interventions. Am J Hypertens (2015) 0.78
Diabetic kidneys do deserve a lifestyle change. Lancet Diabetes Endocrinol (2014) 0.77
The Look AHEAD Trial: bone loss at 4-year follow-up in type 2 diabetes. Diabetes Care (2014) 0.77
Baseline predictors of missed visits in the Look AHEAD study. Obesity (Silver Spring) (2014) 0.77
Effect of a Long-Term Intensive Lifestyle Intervention on Cognitive Function: Action for Health in Diabetes Study. J Am Geriatr Soc (2017) 0.77
Impact of weight loss on ankle-brachial index and interartery blood pressures. Obesity (Silver Spring) (2014) 0.76
The relationship of social support with treatment adherence and weight loss in Latinos with type 2 diabetes. Obesity (Silver Spring) (2016) 0.76
Genetic Predictors of Depressive Symptoms in the Look AHEAD Trial. Psychosom Med (2015) 0.75
The Look AHEAD study: a missed opportunity--authors' reply. Lancet Diabetes Endocrinol (2014) 0.75
Cost of intervention delivery in a lifestyle weight loss trial in type 2 diabetes: results from the Look AHEAD clinical trial. Obes Sci Pract (2017) 0.75
Changes in regional body composition over 8 years in a randomized lifestyle trial: The look AHEAD study. Obesity (Silver Spring) (2016) 0.75
Effects of a long-term lifestyle modification programme on peripheral neuropathy in overweight or obese adults with type 2 diabetes: the Look AHEAD study. Diabetologia (2017) 0.75
Can an intensive diet and exercise program prevent knee pain among overweight adults at high risk? Arthritis Care Res (Hoboken) (2015) 0.75
A common variant in the CLDN7/ELP5 locus predicts adiponectin change with lifestyle intervention and improved fitness in obese individuals with diabetes. Physiol Genomics (2015) 0.75
Impact of intensive lifestyle intervention on preference-based quality of life in type 2 diabetes: Results from the Look AHEAD trial. Obesity (Silver Spring) (2016) 0.75
Intensive Weight Loss Intervention and Cancer Risk in Adults with Type 2 Diabetes: Analysis of the Look AHEAD Randomized Clinical Trial. Obesity (Silver Spring) (2020) 0.75