Xanthine oxidase injurious response in acute joint injury.

The Overexpression of NALP3 Inflammasome in Knee Osteoarthritis Is Associated with Synovial Membrane Prolidase and NADPH Oxidase 2. Oxid Med Cell Longev (2016) 1.40

Radiological assessment of osteo-arthrosis. Ann Rheum Dis (1957) 42.98

The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis. Am J Sports Med (2007) 7.58

Free radical-mediated oxidation of free amino acids and amino acid residues in proteins. Amino Acids (2003) 3.66

The regulation of rat liver xanthine oxidase. Conversion in vitro of the enzyme activity from dehydrogenase (type D) to oxidase (type O). J Biol Chem (1969) 2.65

Xanthine oxidase: biochemistry, distribution and physiology. Acta Physiol Scand Suppl (1986) 2.44

The role of reactive oxygen species in homeostasis and degradation of cartilage. Osteoarthritis Cartilage (2003) 2.27

Carbonyl modified proteins in cellular regulation, aging, and disease. Free Radic Biol Med (2002) 2.23

Structure and function of xanthine oxidoreductase: where are we now? Free Radic Biol Med (2002) 2.06

Oxygen and reactive oxygen species in cartilage degradation: friends or foes? Osteoarthritis Cartilage (2005) 1.93

Flavoprotein structure and mechanism. 4. Xanthine oxidase and xanthine dehydrogenase. FASEB J (1995) 1.84

Proteolytic conversion of xanthine dehydrogenase from the NAD-dependent type to the O2-dependent type. Amino acid sequence of rat liver xanthine dehydrogenase and identification of the cleavage sites of the enzyme protein during irreversible conversion by trypsin. J Biol Chem (1990) 1.73

Evidence for altered synthesis of type II collagen in patients with osteoarthritis. J Clin Invest (1998) 1.66

Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254). Arthritis Res Ther (2010) 1.61

Changes in joint cartilage aggrecan after knee injury and in osteoarthritis. Arthritis Rheum (1999) 1.59

Xanthine oxidoreductase is central to the evolution and function of the innate immune system. Trends Immunol (2003) 1.44

Conversion of xanthine dehydrogenase into xanthine oxidase in rat liver and plasma at the onset of reperfusion after ischemia. Hepatology (1994) 1.41

Trauma: the role of the innate immune system. World J Emerg Surg (2006) 1.37

Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254). Osteoarthritis Cartilage (2012) 1.30

The physiology of endothelial xanthine oxidase: from urate catabolism to reperfusion injury to inflammatory signal transduction. Microcirculation (2002) 1.26

Xanthine oxidoreductase is present in human synovium. Ann Rheum Dis (1987) 1.21

Binding of xanthine oxidase to glycosaminoglycans limits inhibition by oxypurinol. J Biol Chem (2004) 1.09

Xanthine oxidase binding to glycosaminoglycans: kinetics and superoxide dismutase interactions of immobilized xanthine oxidase-heparin complexes. Arch Biochem Biophys (1997) 1.07

Whole-body bone scintigraphy provides a measure of the total-body burden of osteoarthritis for the purpose of systemic biomarker validation. Arthritis Rheum (2009) 1.02

Effects of hyaluronic acid on mitochondrial function and mitochondria-driven apoptosis following oxidative stress in human chondrocytes. J Biol Chem (2009) 1.01

An explorative study comparing levels of soluble mediators in control and osteoarthritic synovial fluid. Osteoarthritis Cartilage (2013) 1.00

Elevated levels of xanthine oxidase in serum of patients with inflammatory and autoimmune rheumatic diseases. Inflammation (1993) 0.99

Serum xanthine oxidase and liver disease. Digestion (1972) 0.90

Changes in Cytokines and Aggrecan ARGS Neoepitope in Synovial Fluid and Serum and in C-Terminal Crosslinking Telopeptide of Type II Collagen and N-Terminal Crosslinking Telopeptide of Type I Collagen in Urine Over Five Years After Anterior Cruciate Ligament Rupture: An Exploratory Analysis in the Knee Anterior Cruciate Ligament, Nonsurgical Versus Surgical Treatment Trial. Arthritis Rheumatol (2015) 0.89

The Relationship between Anterior Cruciate Ligament Injury and Osteoarthritis of the Knee. Adv Orthop (2015) 0.89

Nitric oxide inactivates xanthine dehydrogenase and xanthine oxidase in interferon-gamma-stimulated macrophages. Am J Respir Cell Mol Biol (1994) 0.88

The distribution pattern of critically short telomeres in human osteoarthritic knees. Arthritis Res Ther (2012) 0.87

Xanthine oxidase increase in polymorphonuclear leucocytes and macrophages in mice in three pathological situations. Biochem Pharmacol (1980) 0.86

Reactive oxygen species: the 2-edged sword of osteoarthritis. Am J Med Sci (2012) 0.85

Determination of human plasma xanthine oxidase activity by high-performance liquid chromatography. J Chromatogr B Biomed Appl (1996) 0.85

Evaluation of cartilage damage by measuring collagen degradation products in joint extracts in a traumatic model of osteoarthritis. Biomarkers (2008) 0.82

Urinary CTX-II concentrations are elevated and associated with knee pain and function in subjects with ACL reconstruction. Osteoarthritis Cartilage (2012) 0.82

Serum xanthine oxidase. An experience with 2000 patients. Am J Dig Dis (1973) 0.81

Serum xanthine oxidase in human liver disease. Am J Gastroenterol (2001) 0.81

Induction and activation of procollagenase in rabbit synovial fibroblasts after treatment with active oxygen released by xanthine/xanthine oxidase. Rheumatol Int (1995) 0.77