Published in J Cell Biol on December 07, 2015
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DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility. J Cell Biol (2016) 0.75
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Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. Nat Genet (2003) 5.24
Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. Cell (2001) 4.22
Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nat Genet (2006) 3.97
Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell (2011) 3.95
Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells. Nat Genet (2008) 3.84
The proteome of the mouse photoreceptor sensory cilium complex. Mol Cell Proteomics (2007) 3.53
Unleashing formins to remodel the actin and microtubule cytoskeletons. Nat Rev Mol Cell Biol (2009) 3.45
MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis. J Cell Biol (2011) 3.11
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A positive feedback mechanism governs the polarity and motion of motile cilia. Nature (2007) 2.44
The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization. EMBO Rep (2012) 2.17
RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1. J Cell Sci (2007) 2.14
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Planar cell polarity links axes of spatial dynamics in neural-tube closure. Cell (2012) 1.98
Normal ciliogenesis requires synergy between the cystic kidney disease genes MKS-3 and NPHP-4. J Am Soc Nephrol (2010) 1.85
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ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3. Nat Genet (2013) 1.32
Inturned localizes to the proximal side of wing cells under the instruction of upstream planar polarity proteins. Curr Biol (2004) 1.32
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Nephrocystin-4 is required for pronephric duct-dependent cloaca formation in zebrafish. Hum Mol Genet (2011) 1.07
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Inversin relays Frizzled-8 signals to promote proximal pronephros development. Proc Natl Acad Sci U S A (2010) 1.02
Making the connection: ciliary adhesion complexes anchor basal bodies to the actin cytoskeleton. Dev Cell (2014) 0.98
Control of the Wnt pathways by nephrocystin-4 is required for morphogenesis of the zebrafish pronephros. Hum Mol Genet (2011) 0.95
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PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube. Dev Dyn (2011) 0.89
Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia. J Biol Chem (2011) 0.87
The Drosophila planar polarity proteins inturned and multiple wing hairs interact physically and function together. Genetics (2010) 0.83
The nphp-2 and arl-13 genetic modules interact to regulate ciliogenesis and ciliary microtubule patterning in C. elegans. PLoS Genet (2014) 0.81
NPHP4 mutation is linked to cerebello-oculo-renal syndrome and male infertility. Clin Genet (2013) 0.79
The Drosophila planar polarity gene multiple wing hairs directly regulates the actin cytoskeleton. Development (2015) 0.79
The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin. Development (2015) 0.78