Published in Gastrointest Tumors on July 18, 2014
Influences of diet and the gut microbiome on epigenetic modulation in cancer and other diseases. Clin Epigenetics (2015) 0.96
Serum Antibodies against Helicobacter pylori Neutrophil Activating Protein in Carriers of IL-4 C-590T Genetic Polymorphism Amplify the Risk of Gastritis and Gastric Cancer. Iran Biomed J (2016) 0.77
Suppressed Helicobacter pylori-associated gastric tumorigenesis in Fat-1 transgenic mice producing endogenous ω-3 polyunsaturated fatty acids. Oncotarget (2016) 0.75
Glutathione peroxidase 7 suppresses cancer cell growth and is hypermethylated in gastric cancer. Oncotarget (2017) 0.75
Global cancer statistics, 2002. CA Cancer J Clin (2005) 119.22
Inflammation and cancer. Nature (2002) 53.78
Helicobacter pylori infection and the development of gastric cancer. N Engl J Med (2001) 17.13
cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci U S A (1996) 16.69
Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J Biol Chem (1995) 12.61
Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res (1995) 11.07
Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer (2002) 10.19
Association between infection with Helicobacter pylori and risk of gastric cancer: evidence from a prospective investigation. BMJ (1991) 9.88
Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature (2000) 8.96
Cytotoxic activity in broth-culture filtrates of Campylobacter pylori. J Med Microbiol (1988) 8.69
Pathogenesis of Helicobacter pylori infection. Clin Microbiol Rev (2006) 7.72
SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein. Science (2001) 5.49
Analyses of the cag pathogenicity island of Helicobacter pylori. Mol Microbiol (1998) 5.07
Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma. J Natl Cancer Inst (2002) 4.43
Helicobacter pylori SabA adhesin in persistent infection and chronic inflammation. Science (2002) 4.38
Infections as a major preventable cause of human cancer. J Intern Med (2000) 3.96
Oncogenic mechanisms of the Helicobacter pylori CagA protein. Nat Rev Cancer (2004) 3.88
The disease spectrum of Helicobacter pylori: the immunopathogenesis of gastroduodenal ulcer and gastric cancer. Annu Rev Microbiol (2000) 3.79
A new Helicobacter pylori vacuolating cytotoxin determinant, the intermediate region, is associated with gastric cancer. Gastroenterology (2007) 3.54
A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. Nat Genet (2010) 3.53
Variants of the 3' region of the cagA gene in Helicobacter pylori isolates from patients with different H. pylori-associated diseases. J Clin Microbiol (1998) 3.31
Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology (2008) 3.25
c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs. Mol Microbiol (2002) 3.20
Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse. Proc Natl Acad Sci U S A (2008) 3.17
Identification of genetic loci associated with Helicobacter pylori serologic status. JAMA (2013) 3.15
Helicobacter pylori infection in the pathogenesis of duodenal ulcer and gastric cancer: a model. Gastroenterology (1997) 3.04
Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms. Gastroenterology (2008) 2.63
Helicobacter infection and gastric neoplasia. J Pathol (2006) 2.54
Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity. Nature (2007) 2.48
Helicobacter pylori immune escape is mediated by dendritic cell-induced Treg skewing and Th17 suppression in mice. Gastroenterology (2009) 2.22
Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori. Nat Rev Microbiol (2013) 2.16
The role of T cell subsets and cytokines in the pathogenesis of Helicobacter pylori gastritis in mice. J Immunol (2001) 2.08
Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation. J Biol Chem (2004) 2.01
Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells. Proc Natl Acad Sci U S A (2005) 1.89
The effect of migration on cancer incidence among Japanese in Hawaii. Ethn Dis (2004) 1.72
Helicobacter pylori-induced peptic ulcer disease is associated with inadequate regulatory T cell responses. Gut (2008) 1.69
Host gastric Lewis expression determines the bacterial density of Helicobacter pylori in babA2 genopositive infection. Gut (2003) 1.66
Gastric dysplasia and gastric cancer: Helicobacter pylori, serum vitamin C, and other risk factors. J Natl Cancer Inst (2000) 1.55
Gastric cancer: new genetic developments. J Surg Oncol (2005) 1.55
Tyrosine-phosphorylated bacterial effector proteins: the enemies within. Trends Microbiol (2005) 1.48
A prospective study of dietary salt intake and gastric cancer incidence in a defined Japanese population: the Hisayama study. Int J Cancer (2006) 1.44
Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation. J Biol Chem (2006) 1.43
Assembly and molecular mode of action of the Helicobacter pylori Cag type IV secretion apparatus. FEBS J (2011) 1.35
Eradication of gastric cancer is now both possible and practical. Semin Cancer Biol (2013) 1.28
Helicobacter pylori strain types and risk of gastric cancer: a case-control study. Cancer Epidemiol Biomarkers Prev (2000) 1.24
Helicobacter pylori CagA -- a bacterial intruder conspiring gastric carcinogenesis. Int J Cancer (2006) 1.21
CagA+ Helicobacter pylori infection and gastric cancer risk in the EPIC-EURGAST study. Int J Cancer (2007) 1.18
Outer membrane protein expression profile in Helicobacter pylori clinical isolates. Infect Immun (2009) 1.15
Helicobacter pylori impairs murine dendritic cell responses to infection. PLoS One (2010) 1.08
Helicobacter pylori vacuolating cytotoxin A (VacA) engages the mitochondrial fission machinery to induce host cell death. Proc Natl Acad Sci U S A (2011) 1.08
African, Asian or Indian enigma, the East Asian Helicobacter pylori: facts or medical myths. J Dig Dis (2009) 1.07
Risk factors for the gastric cardia cancer: a case-control study in Fujian Province. World J Gastroenterol (2003) 1.07
cagA-positive Helicobacter pylori and risk for developing gastric carcinoma in Brazil. Int J Cancer (1998) 1.06
Helicobacter pylori cytotoxin-associated genotype and gastric precancerous lesions. J Natl Cancer Inst (2007) 1.00
Roadmap to eliminate gastric cancer with Helicobacter pylori eradication and consecutive surveillance in Japan. J Gastroenterol (2013) 1.00
Helicobacter pylori cag pathogenicity island genes: clinical relevance for peptic ulcer disease development in Brazil. J Med Microbiol (2007) 0.98
Helicobacter pylori virulence factor genotypes in children in the United States: clues about genotype and outcome relationships. J Clin Microbiol (2010) 0.97
Helicobacter pylori and the molecular pathogenesis of intestinal-type gastric carcinoma. Expert Rev Anticancer Ther (2014) 0.97
H. pylori infection is associated with DNA damage of Lgr5-positive epithelial stem cells in the stomach of patients with gastric cancer. Dig Dis Sci (2012) 0.96
The impact of autophagic processes on the intracellular fate of Helicobacter pylori: more tricks from an enigmatic pathogen? Autophagy (2013) 0.95
Helicobacter pylori VacA toxin/subunit p34: targeting of an anion channel to the inner mitochondrial membrane. PLoS Pathog (2010) 0.95
homB status of Helicobacter pylori as a novel marker to distinguish gastric cancer from duodenal ulcer. J Clin Microbiol (2009) 0.95
Deficiency in OGG1 protects against inflammation and mutagenic effects associated with H. pylori infection in mouse. Helicobacter (2006) 0.94
Helicobacter pylori adhesins: review and perspectives. Helicobacter (2000) 0.94
Helicobacter pylori: from the benign to the malignant. Am J Gastroenterol (1999) 0.93
Electric refrigerator use and gastric cancer risk. Br J Cancer (1990) 0.93
Modulation of autophagy by Helicobacter pylori and its role in gastric carcinogenesis. Trends Microbiol (2013) 0.92
Common genetic variants in the 9p21 region and their associations with multiple tumours. Br J Cancer (2013) 0.92
Long-term infection with Helicobacter felis and inactivation of the tumour suppressor gene p53 cumulatively enhance the gastric mutation frequency in Big Blue transgenic mice. J Pathol (2003) 0.89
Signal transduction of Helicobacter pylori during interaction with host cell protein receptors of epithelial and immune cells. Gut Microbes (2013) 0.89
Host genetic factors respond to pathogenic step-specific virulence factors of Helicobacter pylori in gastric carcinogenesis. Mutat Res Rev Mutat Res (2013) 0.85
A prospective study of vitamin and mineral supplement use and the risk of upper gastrointestinal cancers. PLoS One (2014) 0.84
Dietary Habits, demographical, and socio-economical risk factors of the newly diagnosed gastric cancers in the Eastern Anatolia Region of Turkey: an endemic upper gastrointestinal cancer region. Dig Dis Sci (2009) 0.82
A new type of intrabacterial nanotransportation system for VacA in Helicobacter pylori. Med Mol Morphol (2014) 0.81
Helicobacter pylori gastritis in HIV-infected patients: a review. Helicobacter (2014) 0.81
Role of gene polymorphisms in gastric cancer and its precursor lesions: current knowledge and perspectives in Latin American countries. World J Gastroenterol (2014) 0.80
Dietary factors and gastric cancer risk: hospital-based case control study. J BUON (2010) 0.79
Role of Helicobacter pylori virulence factors for iron acquisition from gastric epithelial cells of the host and impact on bacterial colonization. Future Microbiol (2011) 0.77
Case-control study of dietary pattern and other risk factors for gastric cancer. Health Promot Perspect (2012) 0.76
Erythrocyte Lewis (A+B-) host phenotype is a factor with familial clustering for increased risk of Helicobacter pylori-related non-cardiac gastric cancer. J Gastroenterol Hepatol (2006) 0.76