Published in J Cancer Res Clin Oncol on December 31, 2015
Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst (2004) 14.97
Colorectal cancer statistics, 2014. CA Cancer J Clin (2014) 12.86
PUMA couples the nuclear and cytoplasmic proapoptotic function of p53. Science (2005) 5.49
Cytoplasmic functions of the tumour suppressor p53. Nature (2009) 5.23
Platinum resistance: the role of DNA repair pathways. Clin Cancer Res (2008) 3.16
The mitochondrial p53 pathway. Biochim Biophys Acta (2008) 2.98
Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma. Gut (2000) 2.56
ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases. Proc Natl Acad Sci U S A (1998) 1.95
Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions. Mol Cell (2004) 1.62
Apoptosis induced by overexpression of hMSH2 or hMLH1. Cancer Res (1999) 1.58
Regulation of p53 tetramerization and nuclear export by ARC. Proc Natl Acad Sci U S A (2007) 1.41
p53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARC. Mol Cell Biol (2007) 1.37
Colorectal cancer: from prevention to personalized medicine. World J Gastroenterol (2014) 1.26
ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance. Cell Death Differ (2005) 1.23
ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer. Cell Cycle (2008) 1.21
Ubiquitination and degradation of the anti-apoptotic protein ARC by MDM2. J Biol Chem (2006) 1.20
Apoptosis repressor with caspase recruitment domain (ARC) is expressed in cancer cells and localizes to nuclei. FEBS Lett (2005) 1.15
Loss of caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation. Cell Cycle (2005) 1.15
The apoptotic regulatory protein ARC (apoptosis repressor with caspase recruitment domain) prevents oxidant stress-mediated cell death by preserving mitochondrial function. J Biol Chem (2001) 1.12
Bcl-w expression in colorectal adenocarcinoma. Br J Cancer (2000) 1.03
Induction of the apoptosis inhibitor ARC by Ras in human cancers. J Biol Chem (2010) 0.96
Apoptosis repressor with caspase recruitment domain, a multifunctional modulator of cell death. J Cell Mol Med (2011) 0.92
Pan-Bcl-2 inhibitor obatoclax delays cell cycle progression and blocks migration of colorectal cancer cells. PLoS One (2014) 0.84
Molecular signaling mechanisms of apoptosis in hereditary non-polyposis colorectal cancer. World J Gastrointest Pathophysiol (2012) 0.84
A novel role for the apoptosis inhibitor ARC in suppressing TNFα-induced regulated necrosis. Cell Death Differ (2014) 0.81
Programmed cell death in colorectal carcinogenesis. Anticancer Res (2000) 0.77