PubRank

Michael F Clarke

Author PubWeight™ 274.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A 2003 59.17
2 In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 2003 20.77
3 Identification of pancreatic cancer stem cells. Cancer Res 2007 18.36
4 Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 2003 14.35
5 Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci U S A 2007 13.58
6 The prognostic role of a gene signature from tumorigenic breast-cancer cells. N Engl J Med 2007 13.39
7 Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003 11.23
8 Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 2009 10.31
9 Applying the principles of stem-cell biology to cancer. Nat Rev Cancer 2003 8.95
10 CDX2 as a Prognostic Biomarker in Stage II and Stage III Colon Cancer. N Engl J Med 2016 8.53
11 Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 2009 8.33
12 Cancer stem cells: models and concepts. Annu Rev Med 2007 8.06
13 Single-cell dissection of transcriptional heterogeneity in human colon tumors. Nat Biotechnol 2011 7.84
14 The biology of cancer stem cells. Annu Rev Cell Dev Biol 2007 6.23
15 Self-renewal and solid tumor stem cells. Oncogene 2004 4.60
16 Stem cells in normal breast development and breast cancer. Cell Prolif 2003 4.47
17 The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. Proc Natl Acad Sci U S A 2012 4.20
18 Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy. PLoS One 2008 3.97
19 Bmi1, stem cells, and senescence regulation. J Clin Invest 2004 3.80
20 Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors. Stem Cells 2007 3.60
21 DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency. Cell Stem Cell 2009 3.48
22 Therapeutic implications of cancer stem cells. Curr Opin Genet Dev 2004 3.04
23 Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models. Proc Natl Acad Sci U S A 2010 2.89
24 Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors. Nature 2008 2.82
25 Dysregulated gene expression networks in human acute myelogenous leukemia stem cells. Proc Natl Acad Sci U S A 2009 2.76
26 Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation. Nat Med 2006 2.23
27 Recent advances in cancer stem cells. Curr Opin Genet Dev 2008 2.17
28 Cancer stem cells and radiotherapy: new insights into tumor radioresistance. J Natl Cancer Inst 2006 2.10
29 Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer. J Clin Invest 2012 1.92
30 Differential gene expression profiling of adult murine hematopoietic stem cells. Blood 2002 1.69
31 Bmi-1-green fluorescent protein-knock-in mice reveal the dynamic regulation of bmi-1 expression in normal and leukemic hematopoietic cells. Stem Cells 2007 1.57
32 Therapeutic implications of the cancer stem cell hypothesis. Semin Radiat Oncol 2009 1.53
33 Cancer stem cells and tumor metastasis: first steps into uncharted territory. Cell Stem Cell 2007 1.48
34 MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11. Nat Commun 2013 1.43
35 Hematopoietic stem cell self-renewal. Curr Opin Genet Dev 2006 1.42
36 A genetic determinant that specifically regulates the frequency of hematopoietic stem cells. J Immunol 2002 1.41
37 Identification of a cKit(+) colonic crypt base secretory cell that supports Lgr5(+) stem cells in mice. Gastroenterology 2012 1.32
38 Effects of time since fire on birds: how informative are generalized fire response curves for conservation management? Ecol Appl 2012 1.22
39 Automated microfluidic chromatin immunoprecipitation from 2,000 cells. Lab Chip 2009 1.17
40 Usp16 contributes to somatic stem-cell defects in Down's syndrome. Nature 2013 1.13
41 MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion. Breast Cancer Res Treat 2012 1.07
42 Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution. Proc Natl Acad Sci U S A 2012 0.99
43 New oncolytic adenoviruses with hypoxia- and estrogen receptor-regulated replication. Hum Gene Ther 2002 0.99
44 Remodeling of endogenous mammary epithelium by breast cancer stem cells. Stem Cells 2012 0.88
45 Optimal fire histories for biodiversity conservation. Conserv Biol 2014 0.87
46 The Myc connection: ES cells and cancer. Cell 2010 0.87
47 Radiation Therapy Oncology Group translational research program stem cell symposium: incorporating stem cell hypotheses into clinical trials. Int J Radiat Oncol Biol Phys 2009 0.83
48 Neurobiology: at the root of brain cancer. Nature 2004 0.83
49 Oncogenic miRNAs and the perils of losing control of a stem cell's epigenetic identity. Cell Stem Cell 2013 0.80
50 Identifying the metastatic seeds of breast cancer. Nat Biotechnol 2013 0.78
51 SLUGging away at cell death. Cancer Cell 2002 0.77
52 Removal of lactate dehydrogenase-elevating virus from human-in-mouse breast tumor xenografts by cell-sorting. J Virol Methods 2011 0.76
53 CDX2 as a Prognostic Biomarker in Colon Cancer. N Engl J Med 2016 0.75