Microbial profiles at baseline and not the use of antibiotics determine the clinical outcome of the treatment of chronic periodontitis.

PubWeight™: 0.79‹?›

🔗 View Article (PMID 26830979)

Published in Sci Rep on February 01, 2016

Authors

S Bizzarro1, M L Laine1, M J Buijs2, B W Brandt2, W Crielaard2, B G Loos1, E Zaura2

Author Affiliations

1: Department of Periodontology Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, The Netherlands.
2: Department of Preventive Dentistry Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, The Netherlands.

Articles cited by this

Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res (2003) 103.76

Development of a classification system for periodontal diseases and conditions. Ann Periodontol (1999) 12.48

Periodontal diseases. Lancet (2005) 10.13

Evaluation of general 16S ribosomal RNA gene PCR primers for classical and next-generation sequencing-based diversity studies. Nucleic Acids Res (2012) 6.21

Periodontal microbial ecology. Periodontol 2000 (2005) 5.67

Prevalence of periodontitis in adults in the United States: 2009 and 2010. J Dent Res (2012) 5.57

Microbial co-occurrence relationships in the human microbiome. PLoS Comput Biol (2012) 5.35

Survival of human dental plaque flora in various transport media. Appl Microbiol (1972) 4.88

Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing. ISME J (2011) 3.35

The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation. ISME J (2013) 2.90

Prospects for the next anti-Pseudomonas drug. Curr Opin Pharmacol (2009) 2.55

Advances in the progression of periodontitis and proposal of definitions of a periodontitis case and disease progression for use in risk factor research. Group C consensus report of the 5th European Workshop in Periodontology. J Clin Periodontol (2005) 1.98

Deep sequencing of the oral microbiome reveals signatures of periodontal disease. PLoS One (2012) 1.96

Effectiveness of systemic amoxicillin/metronidazole as adjunctive therapy to scaling and root planing in the treatment of chronic periodontitis: a systematic review and meta-analysis. J Periodontol (2012) 1.86

Bacterial community shift in treated periodontitis patients revealed by ion torrent 16S rRNA gene amplicon sequencing. PLoS One (2012) 1.68

Impact of periodontal therapy on the subgingival microbiota of severe periodontitis: comparison between good responders and individuals with refractory periodontitis using the human oral microbe identification microarray. J Periodontol (2012) 1.47

Underestimation of periodontitis in NHANES surveys. J Periodontol (2011) 1.30

Amoxicillin plus metronidazole in the treatment of adult periodontitis patients. A double-blind placebo-controlled study. J Clin Periodontol (2001) 1.27

Has the prevalence of periodontitis changed during the last 30 years? J Clin Periodontol (2008) 1.23

Global oral health inequalities: task group--periodontal disease. Adv Dent Res (2011) 1.14

Phylogenetic and functional gene structure shifts of the oral microbiomes in periodontitis patients. ISME J (2014) 1.12

Significance of Periodontal Risk Assessment in the recurrence of periodontitis and tooth loss. J Clin Periodontol (2009) 1.12

Effects of antibiotics on human microbiota and subsequent disease. Annu Rev Microbiol (2014) 1.08

Subgingival microbiome in smokers and non-smokers in periodontitis: an exploratory study using traditional targeted techniques and a next-generation sequencing. J Clin Periodontol (2013) 1.02

The relation between oral Candida load and bacterial microbiome profiles in Dutch older adults. PLoS One (2012) 1.01

Epidemiology and demographics of aggressive periodontitis. Periodontol 2000 (2014) 0.99

The personal human oral microbiome obscures the effects of treatment on periodontal disease. PLoS One (2014) 0.96

Antibiotic alternatives: the substitution of antibiotics in animal husbandry? Front Microbiol (2014) 0.95

Microbiologic testing and outcomes of full-mouth scaling and root planing with or without amoxicillin/metronidazole in chronic periodontitis. J Periodontol (2010) 0.94

Impact of systemic antimicrobials combined with anti-infective mechanical debridement on the microbiota of generalized aggressive periodontitis: a 6-month RCT. J Clin Periodontol (2011) 0.93

Aggressive periodontitis: case definition and diagnostic criteria. Periodontol 2000 (2014) 0.92

Methanogenic archaea in subgingival sites: a review. APMIS (2012) 0.90

Are there specific benefits of amoxicillin plus metronidazole in Aggregatibacter actinomycetemcomitans-associated periodontitis? Double-masked, randomized clinical trial of efficacy and safety. J Periodontol (2012) 0.89

Stability and resilience of oral microcosms toward acidification and Candida outgrowth by arginine supplementation. Microb Ecol (2014) 0.89

Dynamic changes in the subgingival microbiome and their potential for diagnosis and prognosis of periodontitis. MBio (2015) 0.88

Intraindividual variation in core microbiota in peri-implantitis and periodontitis. Sci Rep (2014) 0.87

Non-surgical periodontal therapy with systemic antibiotics in patients with untreated chronic periodontitis: a systematic review and meta-analysis. J Periodontal Res (2014) 0.86

Innovations in non-surgical periodontal therapy: Consensus Report of the Sixth European Workshop on Periodontology. J Clin Periodontol (2008) 0.85

Antimicrobial susceptibility of moxifloxacin against gram-negative enteric rods from colombian patients with chronic periodontitis. J Periodontol (2010) 0.84

Impact of baseline microbiological status on clinical outcomes in generalized aggressive periodontitis patients treated with or without adjunctive amoxicillin and metronidazole: an exploratory analysis from a randomized controlled clinical trial. J Clin Periodontol (2014) 0.84

Full-mouth ultrasonic debridement associated with amoxicillin and metronidazole in the treatment of severe chronic periodontitis. J Periodontol (2009) 0.83

Sterile paper points as a bacterial DNA-contamination source in microbiome profiles of clinical samples. J Dent (2013) 0.82

Pseudomonas infection in antibody deficient patients. Eur J Microbiol Immunol (Bp) (2014) 0.81

Prevalence of Pseudomonas aeruginosa and Acinetobacter spp. in subgingival biofilm and saliva of subjects with chronic periodontal infection. Braz J Microbiol (2014) 0.81

Clinical and microbiological effects of systemic antimicrobials combined to an anti-infective mechanical debridement for the management of aggressive periodontitis: a 12-month randomized controlled trial. J Clin Periodontol (2013) 0.81

Assessment of periodontal and opportunistic flora in patients with peri-implantitis. Clin Oral Implants Res (2014) 0.81

The repertoire of archaea cultivated from severe periodontitis. PLoS One (2015) 0.80

New and alternative approaches to tackling antibiotic resistance. F1000Prime Rep (2013) 0.80

Metagenomic analysis of subgingival microbiota following non-surgical periodontal therapy: a pilot study. Open Dent J (2012) 0.79

Variables affecting tooth survival and changes in probing depth: a long-term follow-up of periodontitis patients. J Clin Periodontol (2015) 0.79

In vitro efficacy of various antibiotic combinations against Pseudomonas aeruginosa isolates. J Int Med Res (2014) 0.77

Multilevel analysis of bacterial counts from chronic periodontitis after root planing/scaling, surgery, and systemic and local antibiotics: 2-year results. J Oral Microbiol (2013) 0.77