Real-time, portable genome sequencing for Ebola surveillance.

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Published in Nature on February 03, 2016

Authors

Joshua Quick1, Nicholas J Loman1, Sophie Duraffour2,3, Jared T Simpson4,5, Ettore Severi6, Lauren Cowley7, Joseph Akoi Bore2, Raymond Koundouno2, Gytis Dudas8, Amy Mikhail7, Nobila Ouédraogo9, Babak Afrough2,10, Amadou Bah2,11, Jonathan Hj Baum2, Beate Becker-Ziaja2,3, Jan-Peter Boettcher2,12, Mar Cabeza-Cabrerizo2,3, Alvaro Camino-Sanchez2, Lisa L Carter2,13, Juiliane Doerrbecker2,3, Theresa Enkirch2,14, Isabel Graciela García Dorival2,15, Nicole Hetzelt2,12, Julia Hinzmann2,12, Tobias Holm2,3, Liana Eleni Kafetzopoulou2,16, Michel Koropogui2,17, Abigail Kosgey2,18, Eeva Kuisma2,10, Christopher H Logue2,10, Antonio Mazzarelli2,19, Sarah Meisel2,3, Marc Mertens2,20, Janine Michel2,12, Didier Ngabo2,10, Katja Nitzsche2,3, Elisa Pallash2,3, Livia Victoria Patrono2,3, Jasmine Portmann2,21, Johanna Gabriella Repits2,22, Natasha Yasmin Rickett2,15,23, Andrea Sachse2,12, Katrin Singethan2,24, Inês Vitoriano2,10, Rahel L Yemanaberhan2,3, Elsa G Zekeng2,15,23, Racine Trina25, Alexander Bello25, Amadou Alpha Sall26, Ousmane Faye26, Oumar Faye26, N'Faly Magassouba27, Cecelia V Williams28,29, Victoria Amburgey28,29, Linda Winona28,29, Emily Davis29,30, Jon Gerlach29,30, Franck Washington29,30, Vanessa Monteil31, Marine Jourdain31, Marion Bererd31, Alimou Camara31, Hermann Somlare31, Abdoulaye Camara31, Marianne Gerard31, Guillaume Bado31, Bernard Baillet31, Déborah Delaune32,33, Koumpingnin Yacouba Nebie34, Abdoulaye Diarra34, Yacouba Savane34, Raymond Bernard Pallawo34, Giovanna Jaramillo Gutierrez35, Natacha Milhano36,6, Isabelle Roger34, Christopher J Williams37,6, Facinet Yattara17, Kuiama Lewandowski10, Jamie Taylor38, Philip Rachwal38, Daniel Turner39, Georgios Pollakis15,23, Julian A Hiscox15,23, David A Matthews40, Matthew K O'Shea1,41, Andrew McD Johnston41, Duncan Wilson41, Emma Hutley42, Erasmus Smit43, Antonino Di Caro19, Roman Woelfel2,44, Kilian Stoecker3,44, Erna Fleischmann2,44, Martin Gabriel2,3, Simon A Weller38, Lamine Koivogui45, Boubacar Diallo34, Sakoba Keita17, Andrew Rambaut8,46,47, Pierre Formenty34, Stephan Gunther2,3, Miles W Carroll2,10,48,49

Author Affiliations

1: Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK.
2: The European Mobile Laboratory Consortium, Bernhard-Nocht-Institute for Tropical Medicine, D-20359 Hamburg, Germany.
3: Bernhard-Nocht-Institute for Tropical Medicine, D-20359 Hamburg, Germany.
4: Ontario Institute for Cancer Research, Toronto, Canada.
5: Department of Computer Science, University of Toronto, Toronto, Canada.
6: European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
7: National Infection Service, Public Health England, London, UK.
8: Institute of Evolutionary Biology, University of Edinburgh, Edinburgh EH9 2FL, UK.
9: Postgraduate Training for Applied Epidemiology (PAE, German FETP), Robert Koch Institute, Berlin, Germany.
10: Public Health England, Porton Down, Wiltshire SP4 0JG, UK.
11: Swiss Tropical and Public Health Institute, Basel, Switzerland.
12: Robert Koch Institute, Berlin, Germany.
13: University College London, London, UK.
14: Paul-Ehrlich-Institut, Division of Veterinary Medicine, Langen, Germany.
15: Institute of Infection and Global Health, University of Liverpool, Liverpool, UK.
16: Laboratory for Clinical and Epidemiological Virology, Department of Microbiology and Immunology, KU Leuven, Belgium.
17: Ministry of Health Guinea, Conakry, Guinea.
18: Kenya Medical Research Institute, Nairobi, Kenya.
19: National Institute for Infectious Diseases L. Spallanzani, Rome, Italy.
20: Friedrich-Loeffler-Institute, Greifswald, Germany.
21: Spiez Laboratory, Spiez, Switzerland.
22: Janssen-Cilag, Stockholm, Sweden.
23: NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, University of Liverpool, L69 7BE.
24: Institute of Virology, Technische Universität München, Munich, Germany.
25: Public Health Agency of Canada, Winnipeg, Canada.
26: Institut Pasteur Dakar, Dakar, Senegal.
27: Laboratoire de Fièvres Hémorragiques de Guinée, Conakry, Guinea.
28: Sandia National Laboratories, Albuquerque, New Mexico, USA.
29: Ratoma Ebola Diagnostic Center, Conakry, Guinea.
30: MRIGlobal, Kansas City, USA.
31: Expertise France, Laboratoire K-plan de Forecariah en Guinée, Paris, France.
32: Fédération des Laboratoires - HIA Bégin, Paris, France.
33: Laboratoire de Biologie - Centre de Traitement des Soignants, Conakry, Guinée.
34: World Health Organization, Conakry, Guinea.
35: London School of Hygiene and Tropical Medicine, London, UK.
36: Norwegian Institute of Public Health, Oslo, Norway.
37: Public Health Wales, Cardiff, UK.
38: Defence Science and Technology Laboratory (Dstl) Porton Down, Salisbury SP4 0JQ, UK.
39: Oxford Nanopore Technologies, Oxford, UK.
40: Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK.
41: Academic Department of Military Medicine, Royal Centre for Defence Medicine, Birmingham, UK.
42: Centre of Defence Pathology, Royal Centre of Defence Medicine, Birmingham UK.
43: Queen Elizabeth Hospital, Birmingham, UK.
44: Bundeswehr Institute of Microbiology, Munich, Germany.
45: Institut National de Santé Publique, Conakry, Guinea.
46: Fogarty International Center, National Institutes of Health, Bethesda, USA.
47: Centre for Immunology, Infection and Evolution, University of Edinburgh, Edinburgh EH9 2FL, UK.
48: University of Southampton, South General Hospital, Southampton SO16 6YD, UK.
49: NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, PHE Porton Down, UK.

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