BATMAN-TCM: a Bioinformatics Analysis Tool for Molecular mechANism of Traditional Chinese Medicine.

A multiple biomarker assay for quality assessment of botanical drugs using a versatile microfluidic chip. Sci Rep (2017) 0.75

Large-scale cross-species chemogenomic platform proposes a new drug discovery strategy of veterinary drug from herbal medicines. PLoS One (2017) 0.75

Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet (2000) 336.52

Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res (2003) 103.76

KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res (2011) 30.20

UniProt: a hub for protein information. Nucleic Acids Res (2014) 16.72

DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res (2007) 13.94

Open Babel: An open chemical toolbox. J Cheminform (2011) 11.12

Drug target identification using side-effect similarity. Science (2008) 9.24

A side effect resource to capture phenotypic effects of drugs. Mol Syst Biol (2010) 6.75

Minimum redundancy feature selection from microarray gene expression data. J Bioinform Comput Biol (2005) 6.08

STITCH: interaction networks of chemicals and proteins. Nucleic Acids Res (2007) 4.88

OMIM.org: Online Mendelian Inheritance in Man (OMIM®), an online catalog of human genes and genetic disorders. Nucleic Acids Res (2014) 3.71

Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2014) 3.55

Renin-angiotensin system and cardiovascular risk. Lancet (2007) 3.47

InChI - the worldwide chemical structure identifier standard. J Cheminform (2013) 3.46

TCM Database@Taiwan: the world's largest traditional Chinese medicine database for drug screening in silico. PLoS One (2011) 3.09

Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res (2011) 3.05

Pathview: an R/Bioconductor package for pathway-based data integration and visualization. Bioinformatics (2013) 2.23

BoxPlotR: a web tool for generation of box plots. Nat Methods (2014) 2.21

TCM: Made in China. Nature (2011) 1.86

Functionality pattern matching as an efficient complementary structure/reaction search tool: an open-source approach. Molecules (2010) 1.82

Traditional medicine: a culture in the balance. Nature (2007) 1.80

Network-based relating pharmacological and genomic spaces for drug target identification. PLoS One (2010) 1.68

Moderate cardiac-selective overexpression of angiotensin II type 2 receptor protects cardiac functions from ischaemic injury. Exp Physiol (2011) 1.61

Database of traditional Chinese medicine and its application to studies of mechanism and to prescription validation. Br J Pharmacol (2006) 1.58

β-adrenergic receptor-mediated cardiac contractility is inhibited via vasopressin type 1A-receptor-dependent signaling. Circulation (2014) 1.52

HIT: linking herbal active ingredients to targets. Nucleic Acids Res (2010) 1.50

Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure. Expert Opin Biol Ther (2010) 1.41

TCMID: Traditional Chinese Medicine integrative database for herb molecular mechanism analysis. Nucleic Acids Res (2012) 1.39

Angiotensin II type 2 receptor overexpression preserves left ventricular function after myocardial infarction. Circulation (2002) 1.28

A systematic prediction of multiple drug-target interactions from chemical, genomic, and pharmacological data. PLoS One (2012) 1.27

Combining drug and gene similarity measures for drug-target elucidation. J Comput Biol (2011) 1.23

A system-level investigation into the mechanisms of Chinese Traditional Medicine: Compound Danshen Formula for cardiovascular disease treatment. PLoS One (2012) 1.20

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines. J Cheminform (2014) 1.19

Systems approaches and polypharmacology for drug discovery from herbal medicines: an example using licorice. J Ethnopharmacol (2013) 1.17

Drug target prediction based on the herbs components: the study on the multitargets pharmacological mechanism of qishenkeli acting on the coronary heart disease. Evid Based Complement Alternat Med (2012) 1.13

Identifying compound-target associations by combining bioactivity profile similarity search and public databases mining. J Chem Inf Model (2011) 1.12

Where is the hope for drug discovery? Let history tell the future. Drug Discov Today (2008) 1.12

An Integrative Platform of TCM Network Pharmacology and Its Application on a Herbal Formula, Qing-Luo-Yin. Evid Based Complement Alternat Med (2013) 1.06

Deciphering the combination principles of Traditional Chinese Medicine from a systems pharmacology perspective based on Ma-huang Decoction. J Ethnopharmacol (2013) 0.98

Cardioprotective Effects of Qishenyiqi Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin-Converting Enzyme 2. Evid Based Complement Alternat Med (2012) 0.94

Attenuating effect of post-treatment with QiShen YiQi Pills on myocardial fibrosis in rat cardiac hypertrophy. Clin Hemorheol Microcirc (2012) 0.92

Clinical assessment of complementary treatment with Qishen Yiqi dripping pills on ischemic heart failure: study protocol for a randomized, double-blind, multicenter, placebo-controlled trial (CACT-IHF). Trials (2013) 0.92

QiShenYiQi Pills, a Compound Chinese Medicine, Ameliorates Doxorubicin-Induced Myocardial Structure Damage and Cardiac Dysfunction in Rats. Evid Based Complement Alternat Med (2013) 0.91

Evaluation of analytical methods for connectivity map data. Pac Symp Biocomput (2013) 0.91

China plans to modernize traditional medicine. Nature (2007) 0.90

[Effects of Panax notoginseng saponins on ACE2 and TNF-alpha in rats with post-myocardial infarction-ventricular remodeling]. Zhong Yao Cai (2010) 0.86

Total saponins of panax ginseng inhibiting human endothelium cells' damages induced by angiotensin II via AT1 receptor. J Ethnopharmacol (2011) 0.85

Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodelling. Clin Sci (Lond) (2014) 0.85

DanQi Pill protects against heart failure through the arachidonic acid metabolism pathway by attenuating different cyclooxygenases and leukotrienes B4. BMC Complement Altern Med (2014) 0.83

Investigation into the mechanism of Eucommia ulmoides Oliv. based on a systems pharmacology approach. J Ethnopharmacol (2013) 0.81

Similarity-based prediction for Anatomical Therapeutic Chemical classification of drugs by integrating multiple data sources. Bioinformatics (2015) 0.79

Natural aminoacyl tRNA synthetase fragment enhances cardiac function after myocardial infarction. PLoS One (2014) 0.77

Study on qi deficiency syndrome identification modes of coronary heart disease based on metabolomic biomarkers. Evid Based Complement Alternat Med (2014) 0.86

Energy metabolism disorder and myocardial injury in chronic myocardial ischemia with Qi deficiency and blood stasis syndrome based on 2-DE proteomics. Chin J Integr Med (2012) 0.81

Wnt/β-catenin coupled with HIF-1α/VEGF signaling pathways involved in galangin neurovascular unit protection from focal cerebral ischemia. Sci Rep (2015) 0.80

A Drug-Target Network-Based Approach to Evaluate the Efficacy of Medicinal Plants for Type II Diabetes Mellitus. Evid Based Complement Alternat Med (2013) 0.77

Time-Course of the Effects of QSYQ in Promoting Heart Function in Ameroid Constrictor-Induced Myocardial Ischemia Pigs. Evid Based Complement Alternat Med (2014) 0.77

Identification of metabolic biomarkers in patients with type 2 diabetic coronary heart diseases based on metabolomic approach. Sci Rep (2016) 0.76

Surface-initiated molecularly imprinted polymeric column: In situ synthesis and application for semi-preparative separation by high performance liquid chromatography. J Chromatogr A (2011) 0.76