miRNA regulation of white and brown adipose tissue differentiation and function.

PubWeight™: 0.77‹?›

🔗 View Article (PMID 26898181)

Published in Biochim Biophys Acta on February 16, 2016

Authors

Nathan L Price1, Carlos Fernández-Hernando2

Author Affiliations

1: Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine and Department of Pathology, Yale University School of Medicine, New Haven, CT, USA. Electronic address: nathan.l.price@yale.edu.
2: Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA; Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine and Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.

Articles cited by this

Banting lecture 1988. Role of insulin resistance in human disease. Diabetes (1988) 33.22

Cold-activated brown adipose tissue in healthy men. N Engl J Med (2009) 17.58

Atherosclerosis. Nature (2000) 15.95

Atherosclerosis. the road ahead. Cell (2001) 11.88

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature (2004) 10.32

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. J Clin Invest (2010) 6.96

MicroRNA-143 regulates adipocyte differentiation. J Biol Chem (2004) 6.78

Circulating microRNAs in patients with coronary artery disease. Circ Res (2010) 6.28

MicroRNAs 103 and 107 regulate insulin sensitivity. Nature (2011) 3.98

Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity. J Clin Invest (1995) 3.66

The hormonal control of food intake. Cell (2007) 3.61

Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome--an allostatic perspective. Biochim Biophys Acta (2010) 3.19

MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation. Stem Cells (2010) 3.16

MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity. Diabetes (2009) 3.02

Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes. Mol Endocrinol (2007) 2.61

miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130. Proc Natl Acad Sci U S A (2008) 2.42

Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nat Cell Biol (2011) 2.38

miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARgamma expression. Biochem Biophys Res Commun (2010) 2.28

A role of miR-27 in the regulation of adipogenesis. FEBS J (2009) 2.27

Mir193b-365 is essential for brown fat differentiation. Nat Cell Biol (2011) 2.20

microRNA miR-27b impairs human adipocyte differentiation and targets PPARgamma. Biochem Biophys Res Commun (2009) 1.98

Targeting the circulating microRNA signature of obesity. Clin Chem (2013) 1.95

MiR-21 regulates adipogenic differentiation through the modulation of TGF-beta signaling in mesenchymal stem cells derived from human adipose tissue. Stem Cells (2009) 1.88

MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metab (2013) 1.87

Profiling of circulating microRNAs reveals common microRNAs linked to type 2 diabetes that change with insulin sensitization. Diabetes Care (2014) 1.86

Metabolic consequences of the presence or absence of the thermogenic capacity of brown adipose tissue in mice (and probably in humans). Int J Obes (Lond) (2010) 1.82

MicroRNA expression in human omental and subcutaneous adipose tissue. PLoS One (2009) 1.81

MyomiR-133 regulates brown fat differentiation through Prdm16. Nat Cell Biol (2012) 1.80

Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis. Am J Physiol Endocrinol Metab (2010) 1.78

miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol (2010) 1.75

MicroRNA let-7 regulates 3T3-L1 adipogenesis. Mol Endocrinol (2009) 1.71

Distinct expression of muscle-specific microRNAs (myomirs) in brown adipocytes. J Cell Physiol (2009) 1.67

Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes. Diabetologia (2010) 1.60

miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit. Nat Commun (2013) 1.59

A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway. BMC Genomics (2010) 1.56

FOXO1 represses peroxisome proliferator-activated receptor-gamma1 and -gamma2 gene promoters in primary adipocytes. A novel paradigm to increase insulin sensitivity. J Biol Chem (2006) 1.56

Essential role for miR-196a in brown adipogenesis of white fat progenitor cells. PLoS Biol (2012) 1.53

Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis. Genome Biol (2011) 1.53

MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease. Cardiovasc Res (2013) 1.49

MiR-637 maintains the balance between adipocytes and osteoblasts by directly targeting Osterix. Mol Biol Cell (2011) 1.46

Differential expression of microRNAs in adipose tissue after long-term high-fat diet-induced obesity in mice. PLoS One (2012) 1.41

MicroRNA hsa-miR-138 inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells through adenovirus EID-1. Stem Cells Dev (2010) 1.39

CHANGES IN microRNA (miR) profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes. Clin Exp Pharmacol Physiol (2009) 1.36

Upregulation of miR-22 promotes osteogenic differentiation and inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells by repressing HDAC6 protein expression. Stem Cells Dev (2012) 1.34

Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-alpha. Diabetes (2002) 1.29

Adipose tissue dysfunction in nascent metabolic syndrome. J Obes (2013) 1.26

Adipocyte differentiation of human bone marrow-derived stromal cells is modulated by microRNA-155, microRNA-221, and microRNA-222. Stem Cells Dev (2011) 1.23

Differential miRNA expression in omental adipose tissue and in the circulation of obese patients identifies novel metabolic biomarkers. J Clin Endocrinol Metab (2011) 1.22

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice. Nat Commun (2013) 1.22

miR-133a regulates adipocyte browning in vivo. PLoS Genet (2013) 1.22

Regulation of adipocyte differentiation by activation of serotonin (5-HT) receptors 5-HT2AR and 5-HT2CR and involvement of microRNA-448-mediated repression of KLF5. Mol Endocrinol (2010) 1.17

miR-17-5p and miR-106a are involved in the balance between osteogenic and adipogenic differentiation of adipose-derived mesenchymal stem cells. Stem Cell Res (2012) 1.14

Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy. J Clin Invest (2014) 1.12

microRNA-320/RUNX2 axis regulates adipocytic differentiation of human mesenchymal (skeletal) stem cells. Cell Death Dis (2014) 1.09

MiR-27 orchestrates the transcriptional regulation of brown adipogenesis. Metabolism (2013) 1.08

Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity. BMC Endocr Disord (2011) 1.08

MicroRNA-27 (miR-27) targets prohibitin and impairs adipocyte differentiation and mitochondrial function in human adipose-derived stem cells. J Biol Chem (2013) 1.05

TNFα-induced up-regulation of miR-155 inhibits adipogenesis by down-regulating early adipogenic transcription factors. Biochem Biophys Res Commun (2011) 1.02

MiRNA-181a regulates adipogenesis by targeting tumor necrosis factor-α (TNF-α) in the porcine model. PLoS One (2013) 1.02

Adipogenic differentiation of human mesenchymal stromal cells is down-regulated by microRNA-369-5p and up-regulated by microRNA-371. J Cell Physiol (2011) 1.01

MicroRNA-378 controls classical brown fat expansion to counteract obesity. Nat Commun (2014) 0.96

let-7 enhances osteogenesis and bone formation while repressing adipogenesis of human stromal/mesenchymal stem cells by regulating HMGA2. Stem Cells Dev (2014) 0.96

MicroRNA-15a fine-tunes the level of Delta-like 1 homolog (DLK1) in proliferating 3T3-L1 preadipocytes. Exp Cell Res (2010) 0.95

MicroRNA-344 inhibits 3T3-L1 cell differentiation via targeting GSK3β of Wnt/β-catenin signaling pathway. FEBS Lett (2013) 0.94

MicroRNA-146b promotes adipogenesis by suppressing the SIRT1-FOXO1 cascade. EMBO Mol Med (2013) 0.93

Microvesicle-shuttled miR-130b reduces fat deposition in recipient primary cultured porcine adipocytes by inhibiting PPAR-g expression. J Cell Physiol (2014) 0.93

miR-148a is Associated with Obesity and Modulates Adipocyte Differentiation of Mesenchymal Stem Cells through Wnt Signaling. Sci Rep (2015) 0.92

MicroRNAs are required for the feature maintenance and differentiation of brown adipocytes. Diabetes (2014) 0.92

Circulating miR-130b mediates metabolic crosstalk between fat and muscle in overweight/obesity. Diabetologia (2013) 0.92

MiR-335, an adipogenesis-related microRNA, is involved in adipose tissue inflammation. Cell Biochem Biophys (2014) 0.92

MicroRNA-194 reciprocally stimulates osteogenesis and inhibits adipogenesis via regulating COUP-TFII expression. Cell Death Dis (2014) 0.91

The role of microRNA-26b in human adipocyte differentiation and proliferation. Gene (2013) 0.91

MiR-146b is a regulator of human visceral preadipocyte proliferation and differentiation and its expression is altered in human obesity. Mol Cell Endocrinol (2014) 0.90

MicroRNA-375 promotes 3T3-L1 adipocyte differentiation through modulation of extracellular signal-regulated kinase signalling. Clin Exp Pharmacol Physiol (2011) 0.90

Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity. Diabetes (2013) 0.89

MicroRNA-199a-5p affects porcine preadipocyte proliferation and differentiation. Int J Mol Sci (2014) 0.88

Glucocorticoids transcriptionally regulate miR-27b expression promoting body fat accumulation via suppressing the browning of white adipose tissue. Diabetes (2014) 0.87

Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells. Nucleic Acids Res (2009) 0.87

MiR-143 enhances adipogenic differentiation of 3T3-L1 cells through targeting the coding region of mouse pleiotrophin. FEBS Lett (2011) 0.86

MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1α signaling network. EMBO Rep (2015) 0.86

MiR-93 Controls Adiposity via Inhibition of Sirt7 and Tbx3. Cell Rep (2015) 0.86

MicroRNA-33b downregulates the differentiation and development of porcine preadipocytes. Mol Biol Rep (2014) 0.85

MiR-224 impairs adipocyte early differentiation and regulates fatty acid metabolism. Int J Biochem Cell Biol (2013) 0.85

FFAs and adipokine-mediated regulation of hsa-miR-143 expression in human adipocytes. Mol Biol Rep (2013) 0.84

Relevance of microRNA in metabolic diseases. Crit Rev Clin Lab Sci (2014) 0.82

miR-27 inhibits adipocyte differentiation via suppressing CREB expression. Acta Biochim Biophys Sin (Shanghai) (2014) 0.82

TNFα-induced miR-130 resulted in adipocyte dysfunction during obesity-related inflammation. FEBS Lett (2013) 0.82

Modulation of hsa-miR-26b levels following adipokine stimulation. Mol Biol Rep (2012) 0.82

miR-125a inhibits porcine preadipocytes differentiation by targeting ERRα. Mol Cell Biochem (2014) 0.81

Let-7 microRNA and HMGA2 levels of expression are not inversely linked in adipocytic tumors: analysis of 56 lipomas and liposarcomas with molecular cytogenetic data. Genes Chromosomes Cancer (2011) 0.81

Differential expression of microRNAs in omental adipose tissue from gestational diabetes mellitus subjects reveals miR-222 as a regulator of ERα expression in estrogen-induced insulin resistance. Endocrinology (2014) 0.81

A novel negative regulator of adipogenesis: microRNA-363. Stem Cells (2014) 0.80

Up-regulated miR-145 expression inhibits porcine preadipocytes differentiation by targeting IRS1. Int J Biol Sci (2012) 0.79

TNF-α, IL-6, and leptin increase the expression of miR-378, an adipogenesis-related microRNA in human adipocytes. Cell Biochem Biophys (2014) 0.78

HMGA2 and MDM2 expression in lipomatous tumors with partial, low-level amplification of sequences from the long arm of chromosome 12. Cancer Genet (2011) 0.77

Intravenous injection of microvesicle-delivery miR-130b alleviates high-fat diet-induced obesity in C57BL/6 mice through translational repression of PPAR-γ. J Biomed Sci (2015) 0.77

miR-709 inhibits 3T3-L1 cell differentiation by targeting GSK3β of Wnt/β-catenin signaling. Cell Signal (2014) 0.77

SREBP-1c/MicroRNA 33b Genomic Loci Control Adipocyte Differentiation. Mol Cell Biol (2016) 0.76