A Chimeric Switch-Receptor Targeting PD1 Augments the Efficacy of Second-Generation CAR T Cells in Advanced Solid Tumors.

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Published in Cancer Res on March 15, 2016

Authors

Xiaojun Liu1, Raghuveer Ranganathan2, Shuguang Jiang1, Chongyun Fang1, Jing Sun2, Soyeon Kim2, Kheng Newick2, Albert Lo3, Carl H June1, Yangbing Zhao4, Edmund K Moon5

Author Affiliations

1: Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania.
2: Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania.
3: Department of Biomedical Sciences, School of Veterinary Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania.
4: Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania. edmund.moon@uphs.upenn.edu yangbing@exchange.upenn.edu.
5: Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania. edmund.moon@uphs.upenn.edu yangbing@exchange.upenn.edu.

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