Published in Proc Natl Acad Sci U S A on March 22, 2016
Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet (1999) 55.63
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol (2001) 31.56
Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev (2003) 12.38
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature (1996) 11.46
Cre-lox-regulated conditional RNA interference from transgenes. Proc Natl Acad Sci U S A (2004) 9.33
Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell (2004) 7.01
p53 mutations in cancer. Nat Cell Biol (2013) 5.18
Cloning of the T gene required in mesoderm formation in the mouse. Nature (1990) 4.20
Analysis of Fgf8 gene function in vertebrate development. Cold Spring Harb Symp Quant Biol (1997) 3.51
T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes Dev (1999) 3.13
T-box genes in vertebrate development. Annu Rev Genet (2005) 3.00
Identification of major cell classes in the developing mammalian nervous system. J Neurosci (1985) 2.50
Structure and function of the notochord: an essential organ for chordate development. Development (2005) 2.38
Uncoupling Sonic hedgehog control of pattern and expansion of the developing limb bud. Dev Cell (2008) 2.25
Expression pattern of the Brachyury gene in whole-mount TWis/TWis mutant embryos. Development (1991) 2.09
The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells. J Clin Invest (2010) 1.98
T (brachyury) gene duplication confers major susceptibility to familial chordoma. Nat Genet (2009) 1.95
Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation. Dev Dyn (2008) 1.91
The M-twist gene of Mus is expressed in subsets of mesodermal cells and is closely related to the Xenopus X-twi and the Drosophila twist genes. Dev Biol (1991) 1.60
Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms. Dev Cell (2007) 1.59
The T gene is necessary for normal mesodermal morphogenetic cell movements during gastrulation. Development (1995) 1.58
Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics. Sci Adv (2015) 1.33
Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord. Dev Dyn (2010) 1.29
Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs. Proc Natl Acad Sci U S A (2011) 1.15
The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapies. Cell Death Dis (2013) 1.14
From notochord formation to hereditary chordoma: the many roles of Brachyury. Biomed Res Int (2013) 1.12
Cancer vaccines targeting the epithelial-mesenchymal transition: tissue distribution of brachyury and other drivers of the mesenchymal-like phenotype of carcinomas. Semin Oncol (2012) 1.10
The relationships between notochord and floor plate in vertebrate development revisited. Proc Natl Acad Sci U S A (1998) 0.95
Abnormal placental development and early embryonic lethality in EpCAM-null mice. PLoS One (2009) 0.95
Strategies to target molecules that control the acquisition of a mesenchymal-like phenotype by carcinoma cells. Exp Biol Med (Maywood) (2011) 0.93
Characterization of T gene sequence variants and germline duplications in familial and sporadic chordoma. Hum Genet (2014) 0.92
Foxa1 and Foxa2 are required for formation of the intervertebral discs. PLoS One (2013) 0.92
Effects of the TWis mutation on notochord formation and mesodermal patterning. Mech Dev (1995) 0.89
A mouse line expressing Foxa2-driven Cre recombinase in node, notochord, floorplate, and endoderm. Genesis (2008) 0.88
In vivo knockdown of Brachyury results in skeletal defects and urorectal malformations resembling caudal regression syndrome. Dev Biol (2012) 0.88
Transgenic mouse lines expressing Cre recombinase specifically in posterior notochord and notochord. Genesis (2007) 0.86
Generation of knock-in mice that express nuclear enhanced green fluorescent protein and tamoxifen-inducible Cre recombinase in the notochord from Foxa2 and T loci. Genesis (2013) 0.81
Nature and extent of left/right axis defects in T(Wis) /T(Wis) mutant mouse embryos. Dev Dyn (2014) 0.80
Diplomyelia: caudal duplication of the neural tube in mice. Teratology (1986) 0.76