Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection.

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Published in Amino Acids on April 13, 2016

Authors

Dana M Hardbower1,2, Mohammad Asim2, Tracy Murray-Stewart3, Robert A Casero3, Thomas Verriere2, Nuruddeen D Lewis2, Rupesh Chaturvedi2,4, M Blanca Piazuelo2, Keith T Wilson5,6,7,8,9

Author Affiliations

1: Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 2215 Garland Avenue, 1030C Medical Research Building IV, Nashville, TN, 37232, USA.
2: Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
3: The Sydney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
4: School of Biotechnology, Jawaharlal Nehru University, New Delhi, India.
5: Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 2215 Garland Avenue, 1030C Medical Research Building IV, Nashville, TN, 37232, USA. keith.wilson@vanderbilt.edu.
6: Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. keith.wilson@vanderbilt.edu.
7: Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, TN, USA. keith.wilson@vanderbilt.edu.
8: Center for Mucosal Inflammation and Cancer, Vanderbilt University Medical Center, Nashville, TN, USA. keith.wilson@vanderbilt.edu.
9: Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN, USA. keith.wilson@vanderbilt.edu.

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