MRSA Infections in HIV-Infected People Are Associated with Decreased MRSA-Specific Th1 Immunity.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27093273)

Published in PLoS Pathog on April 19, 2016

Authors

Netanya S Utay1, Annelys Roque2, J Katherina Timmer2, David R Morcock3, Claire DeLeage3, Anoma Somasunderam1, Amy C Weintrob4,5, Brian K Agan4,6, Jacob D Estes3, Nancy F Crum-Cianflone4,7, Daniel C Douek2

Author Affiliations

1: Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, United States of America.
2: Human Immunology Section, Vaccine Research Center, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
3: AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
4: Infectious Disease Clinical Research Program (IDCRP), Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, United States of America.
5: Walter Reed National Military Medical Center, Bethesda, Maryland, United States of America.
6: Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America.
7: Infectious Disease Clinic, Naval Medical Center San Diego, San Diego, California, United States of America.

Articles cited by this

Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol (2003) 15.65

Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome. Nature (2008) 8.17

Interleukin-2 therapy in patients with HIV infection. N Engl J Med (2009) 4.38

Microbial translocation in HIV infection: causes, consequences and treatment opportunities. Nat Rev Microbiol (2012) 2.84

Herpes simplex virus and HIV-1: deciphering viral synergy. Lancet Infect Dis (2008) 2.78

Community-onset methicillin-resistant Staphylococcus aureus skin and soft-tissue infections: impact of antimicrobial therapy on outcome. Clin Infect Dis (2007) 2.47

Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries. Medicine (Baltimore) (2010) 2.33

Dendritic cells and B cells maximize mucosal Th1 memory response to herpes simplex virus. J Exp Med (2008) 1.86

The interleukin-12-mediated pathway of immune events is dysfunctional in human immunodeficiency virus-infected individuals. Blood (1999) 1.74

Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15. Blood (1999) 1.71

Clinical Use of Interferon-gamma. Ann N Y Acad Sci (2009) 1.69

Functional and phenotypic characterization of CD57+CD4+ T cells and their association with HIV-1-induced T cell dysfunction. J Immunol (2005) 1.58

Severely impaired IL-12/IL-18/IFNgamma axis in patients with hyper IgE syndrome. Eur J Clin Invest (2005) 1.52

Increasing rates of community-acquired methicillin-resistant Staphylococcus aureus infections among HIV-infected persons. Int J STD AIDS (2007) 1.43

Treatment and outcomes of infections by methicillin-resistant Staphylococcus aureus at an ambulatory clinic. Antimicrob Agents Chemother (2006) 1.40

Challenges for a universal Staphylococcus aureus vaccine. Clin Infect Dis (2012) 1.36

Inherited IL-12p40 deficiency: genetic, immunologic, and clinical features of 49 patients from 30 kindreds. Medicine (Baltimore) (2013) 1.22

Risk factors and mortality of healthcare-associated and community-acquired Staphylococcus aureus bacteraemia. Clin Microbiol Infect (2011) 1.15

Zoster in patients infected with HIV: a review. Am J Med Sci (2001) 1.08

Marked disparity in incidence of bacterial infections in patients with the acquired immunodeficiency syndrome receiving interleukin-2 or interferon-gamma. Ann Intern Med (1988) 1.05

Methicillin-resistant Staphylococcus aureus (MRSA) infections among HIV-infected persons in the era of highly active antiretroviral therapy: a review of the literature. HIV Med (2012) 0.98

Immunosenescence is associated with presence of Kaposi's sarcoma in antiretroviral treated HIV infection. AIDS (2013) 0.95

Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection. Nat Commun (2015) 0.94

Differential roles of interleukin-18 (IL-18) and IL12 for induction of gamma interferon by staphylococcal cell wall components and superantigens. Infect Immun (2001) 0.93

Prevalence of and risk factors for methicillin-resistant Staphylococcus aureus colonization in HIV infection: a meta-analysis. Clin Infect Dis (2014) 0.88

The role of gamma interferon in acquired host resistance against Staphylococcus aureus infection in mice. FEMS Immunol Med Microbiol (2006) 0.87

The Characterization of Varicella Zoster Virus-Specific T Cells in Skin and Blood during Aging. J Invest Dermatol (2015) 0.85

Interleukin-7 signalling defects in naive CD4+ T cells of HIV patients with CD4+ T-cell deficiency on antiretroviral therapy are associated with T-cell activation and senescence. AIDS (2014) 0.82

Gamma interferon confers resistance to infection with Staphylococcus aureus in human vascular endothelial cells by cooperative proinflammatory and enhanced intrinsic antibacterial activities. Infect Immun (2007) 0.81

Evaluation of VZV-specific cell-mediated immunity in adults infected with HIV-1 by using a simple IFN-γ release assay. J Med Virol (2013) 0.77

Effectiveness of IFN-gamma for liver abscesses in chronic granulomatous disease. J Interferon Cytokine Res (1999) 0.77