Structure-function analysis and genetic interactions of the SmG, SmE, and SmF subunits of the yeast Sm protein ring.

Will the circle be unbroken: specific mutations in the yeast Sm protein ring expose a requirement for assembly factor Brr1, a homolog of Gemin2. RNA (2016) 0.75

The genetic landscape of a cell. Science (2010) 16.52

The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell (1997) 5.28

Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell (1999) 4.57

The yeast MUD2 protein: an interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition. Genes Dev (1994) 3.14

A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell (2008) 2.96

Spinal muscular atrophy. Lancet (2008) 2.92

A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA (1998) 2.55

The yeast splicing factor Mud13p is a commitment complex component and corresponds to CBP20, the small subunit of the nuclear cap-binding complex. Genes Dev (1996) 2.25

Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus. Mol Cell (2002) 2.19

An enhancer screen identifies a gene that encodes the yeast U1 snRNP A protein: implications for snRNP protein function in pre-mRNA splicing. Genes Dev (1993) 2.03

A biochemical function for the Sm complex. Mol Cell (2001) 1.47

Partial purification of the yeast U2 snRNP reveals a novel yeast pre-mRNA splicing factor required for pre-spliceosome assembly. EMBO J (1999) 1.35

Functional organization of the Sm core in the crystal structure of human U1 snRNP. EMBO J (2010) 1.35

Transcriptional pulse-chase analysis reveals a role for a novel snRNP-associated protein in the manufacture of spliceosomal snRNPs. EMBO J (1996) 1.33

The yeast U2A'/U2B complex is required for pre-spliceosome formation. EMBO J (1998) 1.29

Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly. Cell (2011) 1.29

Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors, and RNA decay pathways. J Biol Chem (2008) 1.26

The role of RNP biogenesis in spinal muscular atrophy. Curr Opin Cell Biol (2009) 1.26

The architecture of the spliceosomal U4/U6.U5 tri-snRNP. Nature (2015) 1.24

Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition. Elife (2015) 1.19

Evolution of an RNP assembly system: a minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster. Proc Natl Acad Sci U S A (2008) 1.17

Structural basis of pre-mRNA splicing. Science (2015) 1.16

Structural basis of assembly chaperone- mediated snRNP formation. Mol Cell (2013) 1.13

Identification and characterization of a yeast gene encoding the U2 small nuclear ribonucleoprotein particle B" protein. Mol Cell Biol (1996) 1.13

The 3.8 Å structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis. Science (2016) 1.12

Functional characterization of nuclear localization signals in yeast Sm proteins. Mol Cell Biol (2000) 1.06

Architecture of the spliceosome. Biochemistry (2012) 1.06

Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells. Nucleic Acids Res (2011) 0.97

A BBP-Mud2p heterodimer mediates branchpoint recognition and influences splicing substrate abundance in budding yeast. Nucleic Acids Res (2008) 0.96

Genetic interactions of hypomorphic mutations in the m7G cap-binding pocket of yeast nuclear cap binding complex: an essential role for Cbc2 in meiosis via splicing of MER3 pre-mRNA. RNA (2012) 0.94

Structure-function analysis and genetic interactions of the yeast branchpoint binding protein Msl5. Nucleic Acids Res (2012) 0.94

Structure-function analysis of the 5' end of yeast U1 snRNA highlights genetic interactions with the Msl5*Mud2 branchpoint-binding complex and other spliceosome assembly factors. Nucleic Acids Res (2013) 0.91

Structure-function analysis of the Yhc1 subunit of yeast U1 snRNP and genetic interactions of Yhc1 with Mud2, Nam8, Mud1, Tgs1, U1 snRNA, SmD3 and Prp28. Nucleic Acids Res (2014) 0.87

Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs. RNA (2015) 0.86

Structure-function analysis and genetic interactions of the Yhc1, SmD3, SmB, and Snp1 subunits of yeast U1 snRNP and genetic interactions of SmD3 with U2 snRNP subunit Lea1. RNA (2015) 0.85

Reconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organization. EMBO J (2015) 0.82

Re-refinement of the spliceosomal U4 snRNP core-domain structure. Acta Crystallogr D Struct Biol (2016) 0.81

Structure-function analysis and genetic interactions of the Luc7 subunit of the Saccharomyces cerevisiae U1 snRNP. RNA (2016) 0.76

Structure-function analysis and genetic interactions of the Yhc1, SmD3, SmB, and Snp1 subunits of yeast U1 snRNP and genetic interactions of SmD3 with U2 snRNP subunit Lea1. RNA (2015) 0.85

Fission yeast RNA triphosphatase reads an Spt5 CTD code. RNA (2014) 0.82

Characterization of a novel eukaryal nick-sealing RNA ligase from Naegleria gruberi. RNA (2015) 0.81

RNA polymerase II CTD phospho-sites Ser5 and Ser7 govern phosphate homeostasis in fission yeast. RNA (2015) 0.79

Mechanistic insights into the manganese-dependent phosphodiesterase activity of yeast Dbr1 with bis-p-nitrophenylphosphate and branched RNA substrates. RNA (2016) 0.76

Characterization of the tRNA ligases of pathogenic fungi Aspergillus fumigatus and Coccidioides immitis. RNA (2016) 0.76

Structure-function analysis and genetic interactions of the Luc7 subunit of the Saccharomyces cerevisiae U1 snRNP. RNA (2016) 0.76

Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1. RNA (2015) 0.75