Published in Obesity (Silver Spring) on July 28, 2016
Look AHEAD: Action for Health in Diabetes (LookAHEAD) | NCT00017953
Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation (2005) 43.74
Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial. Diabetes Care (2007) 14.35
Bariatric surgery versus intensive medical therapy for diabetes--3-year outcomes. N Engl J Med (2014) 10.66
Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. Control Clin Trials (2003) 9.97
Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial. Arch Intern Med (2010) 8.77
The Look AHEAD study: a description of the lifestyle intervention and the evidence supporting it. Obesity (Silver Spring) (2006) 8.25
The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci (2006) 7.38
Disability in older adults: evidence regarding significance, etiology, and risk. J Am Geriatr Soc (1997) 5.61
Skeletal muscle mass and distribution in 468 men and women aged 18-88 yr. J Appl Physiol (1985) (2000) 5.24
Baseline characteristics of the randomised cohort from the Look AHEAD (Action for Health in Diabetes) study. Diab Vasc Dis Res (2006) 4.30
Four-year weight losses in the Look AHEAD study: factors associated with long-term success. Obesity (Silver Spring) (2011) 3.62
Lifestyle change and mobility in obese adults with type 2 diabetes. N Engl J Med (2012) 2.90
QDR 4500A dual-energy X-ray absorptiometer underestimates fat mass in comparison with criterion methods in adults. Am J Clin Nutr (2005) 2.66
Changes in body composition in women over six years at midlife: ovarian and chronological aging. J Clin Endocrinol Metab (2006) 2.40
Adipose tissue distribution is different in type 2 diabetes. Am J Clin Nutr (2009) 1.78
The development and description of the comparison group in the Look AHEAD trial. Clin Trials (2011) 1.46
Changes in body composition and its relation to muscle strength in 75-year-old men and women: a 5-year prospective follow-up study of the NORA cohort in Göteborg, Sweden. Nutrition (2009) 1.11
Altered body composition in type 2 diabetes mellitus. Int J Obes (Lond) (2008) 1.10
Changes in body composition over 8 years in a randomized trial of a lifestyle intervention: the look AHEAD study. Obesity (Silver Spring) (2015) 0.94
Portion size and obesity. Adv Nutr (2014) 0.92
Food availability/convenience and obesity. Adv Nutr (2014) 0.90
Growth hormone, body composition, and aging. J Am Geriatr Soc (1985) 0.87
Variety, palatability, and obesity. Adv Nutr (2014) 0.87
Changes in adipose tissue depots and metabolic markers following a 1-year diet and exercise intervention in overweight and obese patients with type 2 diabetes. Diabetes Care (2014) 0.85
A long-term intensive lifestyle intervention and physical function: the look AHEAD Movement and Memory Study. Obesity (Silver Spring) (2014) 0.84
The effects of weight loss approaches on bone mineral density in adults: a systematic review and meta-analysis of randomized controlled trials. Osteoporos Int (2016) 0.83
Physical activity and the progressive change in body composition with aging: current evidence and research issues. Med Sci Sports Exerc (1999) 0.83
Food prices and obesity: a review. Adv Nutr (2014) 0.80
Energy density, energy intake, and body weight regulation in adults. Adv Nutr (2014) 0.79
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 15.58
Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. Control Clin Trials (2003) 9.97
Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes. Diabetes Care (2011) 5.50
Association of an intensive lifestyle intervention with remission of type 2 diabetes. JAMA (2012) 5.15
Effect of a long-term behavioural weight loss intervention on nephropathy in overweight or obese adults with type 2 diabetes: a secondary analysis of the Look AHEAD randomised clinical trial. Lancet Diabetes Endocrinol (2014) 4.30
One-year weight losses in the Look AHEAD study: factors associated with success. Obesity (Silver Spring) (2009) 4.08
Four-year weight losses in the Look AHEAD study: factors associated with long-term success. Obesity (Silver Spring) (2011) 3.62
Eight-year weight losses with an intensive lifestyle intervention: the look AHEAD study. Obesity (Silver Spring) (2014) 3.10
Lifestyle change and mobility in obese adults with type 2 diabetes. N Engl J Med (2012) 2.90
Impact of a weight management program on health-related quality of life in overweight adults with type 2 diabetes. Arch Intern Med (2009) 2.59
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
One-year changes in symptoms of depression and weight in overweight/obese individuals with type 2 diabetes in the Look AHEAD study. Obesity (Silver Spring) (2011) 1.97
Weight loss prevents urinary incontinence in women with type 2 diabetes: results from the Look AHEAD trial. J Urol (2012) 1.85
Do weight loss and adherence cluster within behavioral treatment groups? Obesity (Silver Spring) (2013) 1.83
Effectiveness of lifestyle interventions for individuals with severe obesity and type 2 diabetes: results from the Look AHEAD trial. Diabetes Care (2011) 1.78
Intensive lifestyle intervention improves physical function among obese adults with knee pain: findings from the Look AHEAD trial. Obesity (Silver Spring) (2010) 1.78
Suboptimal control of glycemia, blood pressure, and LDL cholesterol in overweight adults with diabetes: the Look AHEAD Study. J Diabetes Complications (2008) 1.77
Exercise capacity and cardiovascular/metabolic characteristics of overweight and obese individuals with type 2 diabetes: the Look AHEAD clinical trial. Diabetes Care (2007) 1.50
Evaluation of early weight loss thresholds for identifying nonresponders to an intensive lifestyle intervention. Obesity (Silver Spring) (2014) 1.44
Correlates of health-related quality of life in overweight and obese adults with type 2 diabetes. Obesity (Silver Spring) (2006) 1.43
Effect of the look AHEAD study intervention on medication use and related cost to treat cardiovascular disease risk factors in individuals with type 2 diabetes. Diabetes Care (2010) 1.39
Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: the action for health in diabetes. Diabetes Care (2014) 1.38
Action for Health in Diabetes (Look AHEAD) trial: baseline evaluation of selected nutrients and food group intake. J Am Diet Assoc (2009) 1.30
The long-term effectiveness of a lifestyle intervention in severely obese individuals. Am J Med (2013) 1.22
A 1-year lifestyle intervention for weight loss in individuals with type 2 diabetes reduces high C-reactive protein levels and identifies metabolic predictors of change: from the Look AHEAD (Action for Health in Diabetes) study. Diabetes Care (2010) 1.21
Impact of intensive lifestyle intervention on depression and health-related quality of life in type 2 diabetes: the Look AHEAD Trial. Diabetes Care (2014) 1.19
Obesity susceptibility loci and dietary intake in the Look AHEAD Trial. Am J Clin Nutr (2012) 1.18
Consent for genetics studies among clinical trial participants: findings from Action for Health in Diabetes (Look AHEAD). Clin Trials (2006) 1.15
Patterns of weight change associated with long-term weight change and cardiovascular disease risk factors in the Look AHEAD Study. Obesity (Silver Spring) (2012) 1.12
Altered body composition in type 2 diabetes mellitus. Int J Obes (Lond) (2008) 1.10
Neighborhood and weight-related health behaviors in the Look AHEAD (Action for Health in Diabetes) study. BMC Public Health (2010) 1.07
Four-year change in cardiorespiratory fitness and influence on glycemic control in adults with type 2 diabetes in a randomized trial: the Look AHEAD Trial. Diabetes Care (2012) 1.02
Lifestyle intervention improves heart rate recovery from exercise in adults with type 2 diabetes: results from the Look AHEAD study. J Obes (2012) 1.01
Effect of 1 year of an intentional weight loss intervention on bone mineral density in type 2 diabetes: results from the Look AHEAD randomized trial. J Bone Miner Res (2012) 1.01
Neighborhood socioeconomic status, depression, and health status in the Look AHEAD (Action for Health in Diabetes) study. BMC Public Health (2011) 1.00
Cardiovascular disease risk factors, depression symptoms and antidepressant medicine use in the Look AHEAD (Action for Health in Diabetes) clinical trial of weight loss in diabetes. Diabetologia (2010) 0.99
Long-term impact of behavioral weight loss intervention on cognitive function. J Gerontol A Biol Sci Med Sci (2014) 0.98
Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the Look AHEAD randomised clinical trial. Lancet Diabetes Endocrinol (2016) 0.98
Binge eating and weight loss outcomes in overweight and obese individuals with type 2 diabetes: results from the Look AHEAD trial. Arch Gen Psychiatry (2008) 0.96
Weight change in the first 2 months of a lifestyle intervention predicts weight changes 8 years later. Obesity (Silver Spring) (2015) 0.96
Changes in body composition over 8 years in a randomized trial of a lifestyle intervention: the look AHEAD study. Obesity (Silver Spring) (2015) 0.94
Adiponectin and the mediation of HDL-cholesterol change with improved lifestyle: the Look AHEAD Study. J Lipid Res (2012) 0.88
Factors influencing enrollment of African Americans in the Look AHEAD trial. Clin Trials (2011) 0.88
FTO predicts weight regain in the Look AHEAD clinical trial. Int J Obes (Lond) (2013) 0.88
Intensive lifestyle intervention reduces urinary incontinence in overweight/obese men with type 2 diabetes: results from the Look AHEAD trial. J Urol (2014) 0.85
Four-year analysis of cardiovascular disease risk factors, depression symptoms, and antidepressant medicine use in the Look AHEAD (Action for Health in Diabetes) clinical trial of weight loss in diabetes. Diabetes Care (2013) 0.85
Human cardiovascular disease IBC chip-wide association with weight loss and weight regain in the look AHEAD trial. Hum Hered (2013) 0.84
Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Hum Mol Genet (2013) 0.84
Aging and physical function in type 2 diabetes: 8 years of an intensive lifestyle intervention. J Gerontol A Biol Sci Med Sci (2014) 0.84
Intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 0.84
Prevalence and predictors of abnormal cardiovascular responses to exercise testing among individuals with type 2 diabetes: the Look AHEAD (Action for Health in Diabetes) study. Diabetes Care (2010) 0.82
Genetic modifiers of cardiorespiratory fitness response to lifestyle intervention. Med Sci Sports Exerc (2014) 0.81
Effect of an intensive lifestyle intervention on atrial fibrillation risk in individuals with type 2 diabetes: the Look AHEAD randomized trial. Am Heart J (2015) 0.81
Partial Meal Replacement Plan and Quality of the Diet at 1 Year: Action for Health in Diabetes (Look AHEAD) Trial. J Acad Nutr Diet (2015) 0.81
Implications of Look AHEAD for clinical trials and clinical practice. Diabetes Obes Metab (2014) 0.80
Prospective association of a genetic risk score and lifestyle intervention with cardiovascular morbidity and mortality among individuals with type 2 diabetes: the Look AHEAD randomised controlled trial. Diabetologia (2015) 0.80
Systolic Blood Pressure Control Among Individuals With Type 2 Diabetes: A Comparative Effectiveness Analysis of Three Interventions. Am J Hypertens (2015) 0.78
The Look AHEAD Trial: bone loss at 4-year follow-up in type 2 diabetes. Diabetes Care (2014) 0.77
Prospective Association of GLUL rs10911021 With Cardiovascular Morbidity and Mortality Among Individuals With Type 2 Diabetes: The Look AHEAD Study. Diabetes (2015) 0.77
Baseline predictors of missed visits in the Look AHEAD study. Obesity (Silver Spring) (2014) 0.77
Diabetic kidneys do deserve a lifestyle change. Lancet Diabetes Endocrinol (2014) 0.77
Effect of a Long-Term Intensive Lifestyle Intervention on Cognitive Function: Action for Health in Diabetes Study. J Am Geriatr Soc (2017) 0.77
Impact of weight loss on ankle-brachial index and interartery blood pressures. Obesity (Silver Spring) (2014) 0.76
The relationship of social support with treatment adherence and weight loss in Latinos with type 2 diabetes. Obesity (Silver Spring) (2016) 0.76
A common variant in the CLDN7/ELP5 locus predicts adiponectin change with lifestyle intervention and improved fitness in obese individuals with diabetes. Physiol Genomics (2015) 0.75
Effects of a long-term lifestyle modification programme on peripheral neuropathy in overweight or obese adults with type 2 diabetes: the Look AHEAD study. Diabetologia (2017) 0.75
The Look AHEAD study: a missed opportunity--authors' reply. Lancet Diabetes Endocrinol (2014) 0.75
Impact of intensive lifestyle intervention on preference-based quality of life in type 2 diabetes: Results from the Look AHEAD trial. Obesity (Silver Spring) (2016) 0.75
Cost of intervention delivery in a lifestyle weight loss trial in type 2 diabetes: results from the Look AHEAD clinical trial. Obes Sci Pract (2017) 0.75
A comparison of cardiometabolic risk factors in households in rural Uganda with and without a resident with type 2 diabetes, 2012-2013. Prev Chronic Dis (2015) 0.75
Genetic Predictors of Depressive Symptoms in the Look AHEAD Trial. Psychosom Med (2015) 0.75
Can an intensive diet and exercise program prevent knee pain among overweight adults at high risk? Arthritis Care Res (Hoboken) (2015) 0.75
Objectively Assessed Physical Activity and Weight Loss Maintenance among Individuals Enrolled in a Lifestyle Intervention. Obesity (Silver Spring) (2017) 0.75
Demographic factors, workplace factors and active transportation use in the USA: a secondary analysis of 2009 NHTS data. J Epidemiol Community Health (2016) 0.75
Intensive Weight Loss Intervention and Cancer Risk in Adults with Type 2 Diabetes: Analysis of the Look AHEAD Randomized Clinical Trial. Obesity (Silver Spring) (2020) 0.75
Randomized trial reveals that physical activity and energy expenditure are associated with weight and body composition after RYGB. Obesity (Silver Spring) (2017) 0.75