Single Agent and Synergistic Activity of the "First-in-Class" Dual PI3K/BRD4 Inhibitor SF1126 with Sorafenib in Hepatocellular Carcinoma.

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🔗 View Article (PMID 27496136)

Published in Mol Cancer Ther on August 05, 2016

Authors

Alok R Singh1, Shweta Joshi1, Adam M Burgoyne2, Jason K Sicklick3, Sadakatsu Ikeda2, Yuko Kono4, Joseph R Garlich5, Guillermo A Morales5, Donald L Durden6,5,7

Author Affiliations

1: Department of Pediatrics, Moores Cancer Center, University of California San Diego, La Jolla, California.
2: Division of Hematology-Oncology, Moores Cancer Center, University of California San Diego, La Jolla, California.
3: Division of Surgical Oncology, Moores Cancer Center, University of California San Diego, La Jolla, California.
4: Division of Hepatology, Department of Medicine, University of California San Diego, La Jolla, California.
5: SignalRx Pharmaceuticals, San Diego, California.
6: Department of Pediatrics, Moores Cancer Center, University of California San Diego, La Jolla, California. ddurden@ucsd.edu.
7: Division of Pediatric Hematology-Oncology, UCSD Rady Children's Hospital, University of California San Diego Health System, La Jolla, California.

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