DNA methylation profiling in human lung tissue identifies genes associated with COPD.

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Published in Epigenetics on August 26, 2016

Authors

Jarrett D Morrow1, Michael H Cho1,2, Craig P Hersh1,2, Victor Pinto-Plata3, Bartolome Celli2, Nathaniel Marchetti4, Gerard Criner4, Raphael Bueno5, George Washko2, Kimberly Glass1, Augustine M K Choi6, John Quackenbush7, Edwin K Silverman1,2, Dawn L DeMeo1,2

Author Affiliations

1: a Channing Division of Network Medicine, Brigham and Women's Hospital , Boston , MA , USA.
2: b Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital , Boston , MA , USA.
3: c Baystate Health , Springfield , MA , USA.
4: d Division of Pulmonary and Critical Care Medicine, Temple University , Philadelphia , PA , USA.
5: e Division of Thoracic Surgery, Brigham and Women's Hospital , Boston , MA , USA.
6: f Department of Medicine , New York Presbyterian/Weill Cornell Medical Center , New York , NY , USA.
7: g Department of Biostatistics and Computational Biology , Dana-Farber Cancer Institute , Boston , MA , USA.

Associated clinical trials:

Evaluation of COPD (Chronic Obstructive Pulmonary Disease) to Longitudinally Identify Predictive Surrogate Endpoints (ECLIPSE) | NCT00292552

Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD) (COPDGene) | NCT00608764

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