Published in Nat Neurosci on August 29, 2016
Translating genome-wide association findings into new therapeutics for psychiatry. Nat Neurosci (2016) 0.83
Knowledge-Guided Bioinformatics Model for Identifying Autism Spectrum Disorder Diagnostic MicroRNA Biomarkers. Sci Rep (2016) 0.75
MicroRNA-101 Regulates Multiple Developmental Programs to Constrain Excitation in Adult Neural Networks. Neuron (2016) 0.75
Focus on psychiatric disorders. Nat Neurosci (2016) 0.75
A Comparative Review of microRNA Expression Patterns in Autism Spectrum Disorder. Front Psychiatry (2016) 0.75
Beneficial effect of interventional exercise on autistic Fragile X syndrome. J Phys Ther Sci (2017) 0.75
The Sequence Alignment/Map format and SAMtools. Bioinformatics (2009) 232.39
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell (2005) 96.87
Differential expression analysis for sequence count data. Genome Biol (2010) 64.56
BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics (2010) 53.23
MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell (2007) 38.42
Most mammalian mRNAs are conserved targets of microRNAs. Genome Res (2008) 37.16
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol (2013) 32.42
HTSeq--a Python framework to work with high-throughput sequencing data. Bioinformatics (2014) 23.22
WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics (2008) 18.58
A general framework for weighted gene co-expression network analysis. Stat Appl Genet Mol Biol (2005) 17.23
Biological insights from 108 schizophrenia-associated genetic loci. Nature (2014) 16.13
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet (2013) 13.17
Discovering microRNAs from deep sequencing data using miRDeep. Nat Biotechnol (2008) 10.17
Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature (2011) 10.16
A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat Biotechnol (2007) 9.90
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
Spatio-temporal transcriptome of the human brain. Nature (2011) 9.19
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell (2011) 8.46
Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R. Bioinformatics (2007) 7.72
Regulation of microRNA biogenesis. Nat Rev Mol Cell Biol (2014) 7.41
Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature (2009) 7.39
Functional organization of the transcriptome in human brain. Nat Neurosci (2008) 7.02
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PLoS Genet (2011) 6.20
The contribution of de novo coding mutations to autism spectrum disorder. Nature (2014) 5.94
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. Nucleic Acids Res (2011) 5.83
Neuroanatomy of autism. Trends Neurosci (2008) 5.59
Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs. Nat Struct Mol Biol (2011) 5.57
The sva package for removing batch effects and other unwanted variation in high-throughput experiments. Bioinformatics (2012) 4.48
miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions. Nucleic Acids Res (2013) 4.19
Most genetic risk for autism resides with common variation. Nat Genet (2014) 4.10
Removing technical variability in RNA-seq data using conditional quantile normalization. Biostatistics (2012) 3.74
Characterization of the proteome, diseases and evolution of the human postsynaptic density. Nat Neurosci (2010) 3.67
Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease. Neuron (2010) 3.49
Is my network module preserved and reproducible? PLoS Comput Biol (2011) 2.91
miRanalyzer: a microRNA detection and analysis tool for next-generation sequencing experiments. Nucleic Acids Res (2009) 2.90
Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism. Cell (2013) 2.87
Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways. Proc Natl Acad Sci U S A (2010) 2.85
Advances in autism. Annu Rev Med (2009) 2.75
AutDB: a gene reference resource for autism research. Nucleic Acids Res (2008) 2.62
INRICH: interval-based enrichment analysis for genome-wide association studies. Bioinformatics (2012) 2.57
Individual common variants exert weak effects on the risk for autism spectrum disorderspi. Hum Mol Genet (2012) 2.46
From neural development to cognition: unexpected roles for chromatin. Nat Rev Genet (2013) 2.42
miRanalyzer: an update on the detection and analysis of microRNAs in high-throughput sequencing experiments. Nucleic Acids Res (2011) 2.25
Genome-wide inference of natural selection on human transcription factor binding sites. Nat Genet (2013) 2.03
MicroRNAs in neuronal function and dysfunction. Trends Neurosci (2012) 1.94
FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders. Cell (2015) 1.94
Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci. Neuron (2015) 1.91
GO-Elite: a flexible solution for pathway and ontology over-representation. Bioinformatics (2012) 1.91
Single-cell genome sequencing: current state of the science. Nat Rev Genet (2016) 1.62
Gene hunting in autism spectrum disorder: on the path to precision medicine. Lancet Neurol (2015) 1.62
Cortical evolution: judge the brain by its cover. Neuron (2013) 1.54
From the genetic architecture to synaptic plasticity in autism spectrum disorder. Nat Rev Neurosci (2015) 1.44
Cadherins and neuropsychiatric disorders. Brain Res (2012) 1.40
The role of epidermal growth factor and its receptors in mammalian CNS. Cytokine Growth Factor Rev (2004) 1.23
Evidence for the biogenesis of more than 1,000 novel human microRNAs. Genome Biol (2014) 1.23
The Emerging Role of microRNAs in Schizophrenia and Autism Spectrum Disorders. Front Psychiatry (2012) 1.22
A quantitative framework to evaluate modeling of cortical development by neural stem cells. Neuron (2014) 1.20
Development of strategies for SNP detection in RNA-seq data: application to lymphoblastoid cell lines and evaluation using 1000 Genomes data. PLoS One (2013) 1.19
Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders. Nat Rev Genet (2015) 1.14
The fibroblast growth factor system and mood disorders. Biol Psychiatry (2006) 1.14
Mechanisms of polarized membrane trafficking in neurons -- focusing in on endosomes. Mol Cell Neurosci (2011) 1.13
Serum microRNA profiles in children with autism. Mol Autism (2014) 1.08
Genetics and genomics of psychiatric disease. Science (2015) 1.08
SV2 acts via presynaptic calcium to regulate neurotransmitter release. Neuron (2010) 1.08
A Primate lncRNA Mediates Notch Signaling during Neuronal Development by Sequestering miRNA. Neuron (2016) 0.79
Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex. Mol Autism (2015) 0.78