Published in Proc Natl Acad Sci U S A on June 01, 1978
Allele frequencies at microsatellite loci: the stepwise mutation model revisited. Genetics (1993) 8.60
VNTR allele frequency distributions under the stepwise mutation model: a computer simulation approach. Genetics (1993) 8.22
Microsatellite variation in honey bee (Apis mellifera L.) populations: hierarchical genetic structure and test of the infinite allele and stepwise mutation models. Genetics (1995) 3.09
Temporal analysis of archived samples indicates marked genetic changes in declining North Sea cod (Gadus morhua). Proc Biol Sci (2003) 2.42
Dual origins of Finns revealed by Y chromosome haplotype variation. Am J Hum Genet (1998) 2.21
Surnames and the Y chromosome. Am J Hum Genet (2000) 1.92
Microsatellite polymorphism in natural populations of the wild plant Arabidopsis thaliana. Genetics (1997) 1.89
Microsatellite evolution inferred from human-chimpanzee genomic sequence alignments. Proc Natl Acad Sci U S A (2002) 1.59
Genetic structure of fragmented southern populations of African Cape buffalo (Syncerus caffer caffer). BMC Evol Biol (2014) 1.40
Measurement of mutational flow implies both a high new-mutation rate for Huntington disease and substantial underascertainment of late-onset cases. Am J Hum Genet (2001) 1.39
When genetic distance matters: measuring genetic differentiation at microsatellite loci in whole-genome scans of recent and incipient mosquito species. Proc Natl Acad Sci U S A (2001) 1.37
Late Pleistocene climate change and the global expansion of anatomically modern humans. Proc Natl Acad Sci U S A (2012) 1.28
DNA identification by pedigree likelihood ratio accommodating population substructure and mutations. Investig Genet (2010) 1.20
Balancing selection in the wild: testing population genetics theory of self-incompatibility in the rare species Brassica insularis. Genetics (2005) 1.17
Challenges to assessing connectivity between massive populations of the Australian plague locust. Proc Biol Sci (2011) 1.15
Evidence that two main bottleneck events shaped modern human genetic diversity. Proc Biol Sci (2009) 1.11
Mutation and evolution of microsatellite loci in Neurospora. Genetics (2004) 1.11
Characteristics of polymorphism at a VNTR locus 3' to the apolipoprotein B gene in five human populations. Am J Hum Genet (1992) 1.03
Allelic associations of two polymorphic microsatellites in intron 40 of the human von Willebrand factor gene. Proc Natl Acad Sci U S A (1994) 1.03
Cladistic association analysis of Y chromosome effects on alcohol dependence and related personality traits. Proc Natl Acad Sci U S A (1999) 1.02
Massive sorghum collection genotyped with SSR markers to enhance use of global genetic resources. PLoS One (2013) 1.01
Population genetics of an ecosystem-defining reef coral Pocillopora damicornis in the Tropical Eastern Pacific. PLoS One (2011) 0.98
Microsatellite markers reveal high allelic variation in natural populations of Cryptomeria japonica near refugial areas of the last glacial period. J Plant Res (2005) 0.96
The trimmed-haplotype test for linkage disequilibrium. Am J Hum Genet (2000) 0.95
Microsatellite evolution: Mutations, sequence variation, and homoplasy in the hypervariable avian microsatellite locus HrU10. BMC Evol Biol (2008) 0.93
Rapid radiation in spiny lobsters (Palinurus spp) as revealed by classic and ABC methods using mtDNA and microsatellite data. BMC Evol Biol (2009) 0.93
The number of alleles at a microsatellite defines the allele frequency spectrum and facilitates fast accurate estimation of theta. Mol Biol Evol (2010) 0.92
Low genetic diversity in a marine nature reserve: re-evaluating diversity criteria in reserve design. Proc Biol Sci (2005) 0.91
A strong 'filter' effect of the East China Sea land bridge for East Asia's temperate plant species: inferences from molecular phylogeography and ecological niche modelling of Platycrater arguta (Hydrangeaceae). BMC Evol Biol (2014) 0.90
Population genetic structure of the malaria vector Anopheles nili in sub-Saharan Africa. Malar J (2010) 0.89
Expected Shannon Entropy and Shannon Differentiation between Subpopulations for Neutral Genes under the Finite Island Model. PLoS One (2015) 0.88
Genetic variation and de novo mutations in the parthenogenetic Caucasian rock lizard Darevskia unisexualis. PLoS One (2008) 0.88
Microevolution of pandemic Vibrio parahaemolyticus assessed by the number of repeat units in short sequence tandem repeat regions. PLoS One (2012) 0.88
Siring success and paternal effects in heterodichogamous Acer opalus. Ann Bot (2008) 0.87
Motif mismatches in microsatellites: insights from genome-wide investigation among 20 insect species. DNA Res (2014) 0.86
Detecting and Removing Ascertainment Bias in Microsatellites from the HGDP-CEPH Panel. G3 (Bethesda) (2011) 0.86
Population structure and historical demography of South American sea lions provide insights into the catastrophic decline of a marine mammal population. R Soc Open Sci (2016) 0.85
B chromosome polymorphism in maize landraces: adaptive vs. demographic hypothesis of clinal variation. Genetics (2007) 0.84
From Late Miocene to Holocene: processes of differentiation within the Telestes genus (Actinopterygii: Cyprinidae). PLoS One (2012) 0.84
Intestinal stem cell division and genetic diversity. A computer and experimental analysis. Am J Pathol (1997) 0.83
Current and historical drivers of landscape genetic structure differ in core and peripheral salamander populations. PLoS One (2012) 0.82
Population genetic structure of the malaria vector Anopheles funestus, in a recently re-colonized area of the Senegal River basin and human-induced environmental changes. Parasit Vectors (2012) 0.82
The fewer and the better: prioritization of populations for conservation under limited resources, a genetic study with Borderea pyrenaica (Dioscoreaceae) in the Pyrenean National Park. Genetica (2010) 0.82
Always look on both sides: phylogenetic information conveyed by simple sequence repeat allele sequences. PLoS One (2012) 0.81
Genetic diversity in maize landraces from indigenous settlements of Northeastern Argentina. Genetica (2008) 0.81
Experimental estimation of mutation rates in a wheat population with a gene genealogy approach. Genetics (2008) 0.79
Natural variation of model mutant phenotypes in Ciona intestinalis. PLoS One (2008) 0.79
Determining microsatellite genotyping reliability and mutation detection ability: an approach using small-pool PCR from sperm DNA. Mol Genet Genomics (2010) 0.79
Characterization of demographic expansions from pairwise comparisons of linked microsatellite haplotypes. Genetics (2008) 0.78
Inter-allelic interactions play a major role in microsatellite evolution. Proc Biol Sci (2015) 0.78
Molecular insights into the historic demography of bowhead whales: understanding the evolutionary basis of contemporary management practices. Ecol Evol (2012) 0.77
Towards improvements in the estimation of the coalescent: implications for the most effective use of Y chromosome short tandem repeat mutation rates. PLoS One (2012) 0.77
Evolution of microsatellite Loci of tropical and temperate anguilla eels. Int J Mol Sci (2012) 0.77
Evidence for nonindependent evolution of adjacent microsatellites in the human genome. J Mol Evol (2009) 0.76
Genetic structure of red-handed howler monkey populations in the fragmented landscape of Eastern Brazilian Amazonia. Genet Mol Biol (2010) 0.76
Comparison of genetic diversity and population structure between two Schistosoma japonicum isolates--the field and the laboratory. Parasitol Res (2015) 0.76
Data-driven insights into deletions of Mycobacterium tuberculosis complex chromosomal DR region using spoligoforests. Proceedings (IEEE Int Conf Bioinformatics Biomed) (2011) 0.75
Evaluating the adaptive potential of the European eel: is the immunogenetic status recovering? PeerJ (2016) 0.75
Inferring population structure and relationship using minimal independent evolutionary markers in Y-chromosome: a hybrid approach of recursive feature selection for hierarchical clustering. Nucleic Acids Res (2014) 0.75
Genetic differentiation in red-bellied piranha populations (Pygocentrus nattereri, Kner, 1858) from the Solimões-Amazonas River. Ecol Evol (2016) 0.75
Disentangle the Causes of the Road Barrier Effect in Small Mammals through Genetic Patterns. PLoS One (2016) 0.75
Long-term persisting hybrid swarm and geographic difference in hybridization pattern: genetic consequences of secondary contact between two Vincetoxicum species (Apocynaceae-Asclepiadoideae). BMC Evol Biol (2016) 0.75
Response to: DNA identification by pedigree likelihood ratio accommodating population substructure and mutations- authors' reply. Investig Genet (2011) 0.75
Does asymmetric gene flow among matrilines maintain the evolutionary potential of the European eel? Ecol Evol (2016) 0.75
A computer simulation study of VNTR population genetics: constrained recombination rules out the infinite alleles model. Genetics (1993) 0.75
Three sympatric clusters of the malaria vector Anopheles culicifacies E (Diptera: Culicidae) detected in Sri Lanka. Parasit Vectors (2016) 0.75
Evolutionary History of the Live-Bearing Endemic Allotoca diazi Species Complex (Actinopterygii, Goodeinae): Evidence of Founder Effect Events in the Mexican Pre-Hispanic Period. PLoS One (2015) 0.75
Secondary contact and asymmetrical gene flow in a cosmopolitan marine fish across the Benguela upwelling zone. Heredity (Edinb) (2016) 0.75
Conservation genetics of the capercaillie in Poland - Delineation of conservation units. PLoS One (2017) 0.75
Genetic structure and Wolbachia genotyping in naturally occurring populations of Aedes albopictus across contiguous landscapes of Orissa, India. PLoS One (2014) 0.75
Cryptic population structuring and the role of the Isthmus of Tehuantepec as a gene flow barrier in the critically endangered Central American River Turtle. PLoS One (2013) 0.75
Reverse Transcription Errors and RNA-DNA Differences at Short Tandem Repeats. Mol Biol Evol (2016) 0.75
A comparative genomics approach revealed evolutionary dynamics of microsatellite imperfection and conservation in genus Gossypium. Hereditas (2017) 0.75
THE NUMBER OF ALLELES THAT CAN BE MAINTAINED IN A FINITE POPULATION. Genetics (1964) 45.28
A molecular approach to the study of genic heterozygosity in natural populations. II. Amount of variation and degree of heterozygosity in natural populations of Drosophila pseudoobscura. Genetics (1966) 30.66
The sampling theory of selectively neutral alleles. Theor Popul Biol (1972) 27.35
Statistical studies on protein polymorphism in natural populations. I. Distribution of single locus heterozygosity. Genetics (1977) 17.08
The Distribution of Gene Frequencies Under Irreversible Mutation. Proc Natl Acad Sci U S A (1938) 9.66
Genetic variability maintained in a finite population due to mutational production of neutral and nearly neutral isoalleles. Genet Res (1968) 4.83
Wandering distributions and the electrophoretic profile. Theor Popul Biol (1975) 4.66
Average heterozygosity per locus in man: an estimate based on the incidence of enzyme polymorphisms. Ann Hum Genet (1972) 4.29
Distribution of allelic frequencies in a finite population under stepwise production of neutral alleles. Proc Natl Acad Sci U S A (1975) 3.64
Mutation and evolution at the molecular level. Genetics (1973) 2.79
Statistical analyses of Drosophila and human protein polymorphisms. Proc Natl Acad Sci U S A (1975) 1.63
Theoretical study of genetic variability, assuming stepwise production of neutral and very slightly deleterious mutations. Proc Natl Acad Sci U S A (1978) 1.26
Wandering distributions and the electrophoretic profile. II. Theor Popul Biol (1976) 1.22
A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. J Mol Evol (1980) 113.75
Evolutionary rate at the molecular level. Nature (1968) 33.15
The number of heterozygous nucleotide sites maintained in a finite population due to steady flux of mutations. Genetics (1969) 22.59
The Average Number of Generations until Fixation of a Mutant Gene in a Finite Population. Genetics (1969) 21.57
Whole genome sequencing of meticillin-resistant Staphylococcus aureus. Lancet (2001) 18.55
Slightly deleterious mutant substitutions in evolution. Nature (1973) 13.79
A model of mutation appropriate to estimate the number of electrophoretically detectable alleles in a finite population. Genet Res (1973) 13.08
A stochastic model concerning the maintenance of genetic variability in quantitative characters. Proc Natl Acad Sci U S A (1965) 9.20
GENIA corpus--semantically annotated corpus for bio-textmining. Bioinformatics (2003) 8.89
Obesity, cigarette smoking, and telomere length in women. Lancet (2005) 8.59
Artemisinins target the SERCA of Plasmodium falciparum. Nature (2003) 7.72
The substitutional load in a finite population. Heredity (Edinb) (1969) 7.56
Linkage disequilibrium at steady state determined by random genetic drift and recurrent mutation. Genetics (1969) 7.33
Role of very slightly deleterious mutations in molecular evolution and polymorphism. Theor Popul Biol (1976) 6.91
The effects of social status on biological aging as measured by white-blood-cell telomere length. Aging Cell (2006) 6.80
Protein polymorphism as a phase of molecular evolution. Nature (1971) 6.68
Theoretical foundation of population genetics at the molecular level. Theor Popul Biol (1971) 6.38
The probability of consanguineous marriages. Genetics (1966) 5.85
Estimation of evolutionary distances between homologous nucleotide sequences. Proc Natl Acad Sci U S A (1981) 5.34
On the stochastic model for estimation of mutational distance between homologous proteins. J Mol Evol (1972) 5.16
On some principles governing molecular evolution. Proc Natl Acad Sci U S A (1974) 4.97
Multilayer white light-emitting organic electroluminescent device. Science (1995) 4.86
Genetic variability maintained in a finite population due to mutational production of neutral and nearly neutral isoalleles. Genet Res (1968) 4.83
The rate of molecular evolution considered from the standpoint of population genetics. Proc Natl Acad Sci U S A (1969) 4.75
Pattern of neutral polymorphism in a geographically structured population. Genet Res (1971) 4.65
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation. J Biol Chem (2001) 4.51
On the constancy of the evolutionary rate of cistrons. J Mol Evol (1971) 4.49
The age of a neutral mutant persisting in a finite population. Genetics (1973) 4.44
Genetic variability and effective population size when local extinction and recolonization of subpopulations are frequent. Proc Natl Acad Sci U S A (1980) 4.37
The basal ganglia and adaptive motor control. Science (1994) 4.27
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. Nat Nanotechnol (2011) 4.22
Telomere length as an indicator of biological aging: the gender effect and relation with pulse pressure and pulse wave velocity. Hypertension (2001) 4.07
Preponderance of synonymous changes as evidence for the neutral theory of molecular evolution. Nature (1977) 4.00
Development of a pertussis component vaccine in Japan. Lancet (1984) 3.94
Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell (1998) 3.80
Distribution of allelic frequencies in a finite population under stepwise production of neutral alleles. Proc Natl Acad Sci U S A (1975) 3.64
On the evolution of multigene families. Theor Popul Biol (1983) 3.61
Population biology of antigen presentation by MHC class I molecules. Science (1996) 3.58
Linkage disequilibrium between two segregating nucleotide sites under the steady flux of mutations in a finite population. Genetics (1971) 3.51
The average number of generations until extinction of an individual mutant gene in a finite population. Genetics (1969) 3.49
Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study. Aging Cell (2006) 3.44
Effect of overall phenotypic selection on genetic change at individual loci. Proc Natl Acad Sci U S A (1978) 3.41
Telomere length inversely correlates with pulse pressure and is highly familial. Hypertension (2000) 3.32
Stem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms. Mol Cell Biol (2000) 2.90
Peptidoglycan synthetic activities in membranes of Escherichia coli caused by overproduction of penicillin-binding protein 2 and rodA protein. J Biol Chem (1986) 2.84
Mutation and evolution at the molecular level. Genetics (1973) 2.79
Allelic and nonallelic homology of a supergene family. Proc Natl Acad Sci U S A (1982) 2.72
Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing. Genes Cells (1998) 2.66
Purification and characterization of the human interleukin-18 receptor. J Biol Chem (1997) 2.58
Simulating evolution by gene duplication. Genetics (1987) 2.52
Fixation of a deleterious allele at one of two "duplicate" loci by mutation pressure and random drift. Proc Natl Acad Sci U S A (1979) 2.51
Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR. J Cancer Res Clin Oncol (1992) 2.40
Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast. Cancer Res (1999) 2.28
Possibility of extensive neutral evolution under stabilizing selection with special reference to nonrandom usage of synonymous codons. Proc Natl Acad Sci U S A (1981) 2.23
Molecular clock of viral evolution, and the neutral theory. Proc Natl Acad Sci U S A (1990) 2.15
Responses of tonically active neurons in the primate's striatum undergo systematic changes during behavioral sensorimotor conditioning. J Neurosci (1994) 2.14
Polyallelic mutational equilibria. Genetics (1975) 2.13
Sequence variation in the 18S rRNA gene, a target for PCR-based malaria diagnosis, in Plasmodium ovale from southern Vietnam. J Clin Microbiol (1996) 2.12
Structural analysis of the dnaA and dnaN genes of Escherichia coli. Gene (1984) 2.11
Inhibitors of efflux pumps in Pseudomonas aeruginosa potentiate the activity of the fluoroquinolone antibacterial levofloxacin. J Med Chem (1999) 2.10
Triplet repeat polymorphism in the transmembrane region of the MICA gene: a strong association of six GCT repetitions with Behçet disease. Proc Natl Acad Sci U S A (1997) 2.10
The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1. Mol Cell Biol (2000) 2.09
The balance between different peptidoglycan precursors determines whether Escherichia coli cells will elongate or divide. J Bacteriol (1990) 2.07
The length of time required for a selectively neutral mutant to reach fixation through random frequency drift in a finite population. Genet Res (1970) 2.05
Isolation of Dictyostelium discoideum cytokinesis mutants by restriction enzyme-mediated integration of the blasticidin S resistance marker. Biochem Biophys Res Commun (1994) 2.05
A gene-counting method of maximum likelihood for estimating gene frequencies in ABO and ABO-like systems. Ann Hum Genet (1968) 2.05
Population genetics of multigene families that are dispersed into two or more chromosomes. Proc Natl Acad Sci U S A (1983) 2.05
Efficiency of truncation selection. Proc Natl Acad Sci U S A (1979) 2.00
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis. Proc Natl Acad Sci U S A (1999) 1.98
Selective constraint in protein polymorphism: study of the effectively neutral mutation model by using an improved pseudosampling method. Proc Natl Acad Sci U S A (1983) 1.98
Nucleotide sequence of the pbpA gene and characteristics of the deduced amino acid sequence of penicillin-binding protein 2 of Escherichia coli K12. Eur J Biochem (1986) 1.98
Simple model for treating evolution of multigene families. Nature (1976) 1.98
Details of an isolation method for hepatic lymphocytes in mice. J Immunol Methods (1992) 1.97
The effect of selected linked locus on heterozygosity of neutral alleles (the hitch-hiking effect). Genet Res (1975) 1.95
Neurons in the thalamic CM-Pf complex supply striatal neurons with information about behaviorally significant sensory events. J Neurophysiol (2001) 1.94
High prevalence of Plasmodium malariae and Plasmodium ovale in malaria patients along the Thai-Myanmar border, as revealed by acridine orange staining and PCR-based diagnoses. Trop Med Int Health (1998) 1.93
Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a. Hum Mol Genet (2003) 1.92
Inhibition of T helper cell type 2 cell differentiation and immunoglobulin E response by ligand-activated Valpha14 natural killer T cells. J Exp Med (1999) 1.88
New approach to cell lineage analysis in mammals using the Cre-loxP system. Mol Reprod Dev (2000) 1.88
Eukaryotes-prokaryotes divergence estimated by 5S ribosomal RNA sequences. Nat New Biol (1973) 1.88
Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons. Am J Hum Genet (2003) 1.82
Cell proliferative activity in intraductal papillary-mucinous neoplasms and invasive ductal adenocarcinomas of the pancreas: an immunohistochemical study. Arch Pathol Lab Med (1998) 1.81
Dominant negative umuD mutations decreasing RecA-mediated cleavage suggest roles for intact UmuD in modulation of SOS mutagenesis. Proc Natl Acad Sci U S A (1990) 1.79
Functional organization of genetic material as a product of molecular evolution. Nature (1971) 1.79
Still's disease associated with necrotizing lymphadenitis (Kikuchi's disease): report of 3 cases. J Rheumatol (1988) 1.78
Systemic toxicity and resuscitation in bupivacaine-, levobupivacaine-, or ropivacaine-infused rats. Anesth Analg (2001) 1.76
Complete nucleotide sequence of the chloroplast genome from the green alga Chlorella vulgaris: the existence of genes possibly involved in chloroplast division. Proc Natl Acad Sci U S A (1997) 1.75
Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5. J Biol Chem (1996) 1.72
Longitudinal versus cross-sectional evaluations of leukocyte telomere length dynamics: age-dependent telomere shortening is the rule. J Gerontol A Biol Sci Med Sci (2011) 1.72