The Effectiveness of Natural Diarylheptanoids against Trypanosoma cruzi: Cytotoxicity, Ultrastructural Alterations and Molecular Modeling Studies.

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Published in PLoS One on September 22, 2016

Authors

Vitor Sueth-Santiago1, Julliane de B B Moraes2, Eliomara Sousa Sobral Alves3, Marcos André Vannier-Santos3, Célio G Freire-de-Lima4, Rosane N Castro1, Gustavo Peron Mendes-Silva1, Catarina de Nigris Del Cistia5, Luma Godoy Magalhães6, Adriano Defini Andricopulo6, Carlos Mauricio R Sant Anna1, Debora Decoté-Ricardo2, Marco Edilson Freire de Lima1

Author Affiliations

1: Universidade Federal Rural do Rio de Janeiro, Instituto de Ciências Exatas, Departamento de Química, BR 465, Km 07, CEP: 23.890-000, Seropédica, RJ, Brazil.
2: Universidade Federal Rural do Rio de Janeiro, Instituto de Veterinária, Departamento de Microbiologia e Imunologia Veterinária, BR 465, Km 07, CEP: 23.890-000, Seropédica, RJ, Brazil.
3: Laboratório de Biologia Parasitária, Centro de Pesquisas Gonçalo Moniz (CPqGM-Fiocruz), Rua Waldemar Falcão, 121, Candeal, CEP: 40.296-710, Salvador, BA, Brazil.
4: Universidade Federal do Rio de Janeiro, Instituto de Biofísica Carlos Chagas Filho, Ilha do Fundão, Cidade Universitária, CEP: 21.941-902, Rio de Janeiro, RJ, Brazil.
5: Universidade Federal Rural do Rio de Janeiro, Instituto de Ciências Exatas, Departamento de Matemática, BR 465, Km 07, CEP: 23.890-000, Seropédica, RJ, Brazil.
6: Laboratório de Química Medicinal e Computacional, Centro de Pesquisa e Inovação em Biodiversidade e Fármacos, Instituto de Física de São Carlos, Universidade de São Paulo, CP 396, CEP: 13.560-970, São Carlos, SP, Brazil.

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