Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27707548)

Published in Ophthalmology on October 01, 2016

Authors

Todd E Scheetz1, Ben Faga1, Lizette Ortega2, Ben R Roos1, Mae O Gordon3, Michael A Kass3, Kai Wang4, John H Fingert5

Author Affiliations

1: Department Ophthalmology and Visual Sciences, University of Iowa, Iowa City, Iowa; Stephen A. Wynn Institute for Vision Research, University of Iowa, Iowa City, Iowa.
2: Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa.
3: Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri.
4: Stephen A. Wynn Institute for Vision Research, University of Iowa, Iowa City, Iowa; Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa.
5: Department Ophthalmology and Visual Sciences, University of Iowa, Iowa City, Iowa; Stephen A. Wynn Institute for Vision Research, University of Iowa, Iowa City, Iowa. Electronic address: john-fingert@uiowa.edu.

Associated clinical trials:

Ocular Hypertension Treatment Study (OHTS) (OHTS) | NCT00000125

Articles citing this

Major review: Molecular genetics of primary open-angle glaucoma. Exp Eye Res (2017) 0.75

Articles cited by this

The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol (2006) 25.47

The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol (2002) 11.38

Identification of a gene that causes primary open angle glaucoma. Science (1997) 8.14

Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma. Science (2007) 7.55

Adult-onset primary open-angle glaucoma caused by mutations in optineurin. Science (2002) 6.53

Primary open-angle glaucoma. N Engl J Med (2009) 4.89

Racial differences in the cause-specific prevalence of blindness in east Baltimore. N Engl J Med (1991) 4.73

Prevalence of open-angle glaucoma in Australia. The Blue Mountains Eye Study. Ophthalmology (1996) 4.46

The Ocular Hypertension Treatment Study: design and baseline description of the participants. Arch Ophthalmol (1999) 3.30

Clinical features associated with mutations in the chromosome 1 open-angle glaucoma gene (GLC1A) N Engl J Med (1998) 3.18

Glaucoma family study. Am J Ophthalmol (1960) 2.78

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma. Nat Genet (2010) 2.75

Prevalence and causes of visual impairment in The Barbados Eye Study. Ophthalmology (2001) 2.70

Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1. Nat Genet (2011) 2.42

Delaying treatment of ocular hypertension: the ocular hypertension treatment study. Arch Ophthalmol (2010) 2.14

Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma. PLoS Genet (2012) 2.00

Family history and risk of primary open angle glaucoma. The Baltimore Eye Survey. Arch Ophthalmol (1994) 1.89

A genome-wide association study of optic disc parameters. PLoS Genet (2010) 1.87

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA. Hum Mol Genet (2011) 1.77

Copy number variations on chromosome 12q14 in patients with normal tension glaucoma. Hum Mol Genet (2011) 1.74

Isolation of DNA from biological specimens without extraction with phenol. Clin Chem (1985) 1.71

Primary open-angle glaucoma genes. Eye (Lond) (2011) 1.60

Common genetic variants associated with open-angle glaucoma. Hum Mol Genet (2011) 1.58

Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness. PLoS Genet (2010) 1.55

Genome-wide association identifies ATOH7 as a major gene determining human optic disc size. Hum Mol Genet (2010) 1.53

Collagen-related genes influence the glaucoma risk factor, central corneal thickness. Hum Mol Genet (2010) 1.52

Genetic determination of cup/disc ratio of the optic nerve. Arch Ophthalmol (1967) 1.50

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. Nat Genet (2013) 1.49

Association of Toll-like receptor 4 gene polymorphisms with normal tension glaucoma. Invest Ophthalmol Vis Sci (2008) 1.43

New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8. Hum Mol Genet (2010) 1.41

Common genetic determinants of intraocular pressure and primary open-angle glaucoma. PLoS Genet (2012) 1.33

Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility. Ophthalmology (2010) 1.28

A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma. Hum Mol Genet (2012) 1.24

Genetic variants associated with optic nerve vertical cup-to-disc ratio are risk factors for primary open angle glaucoma in a US Caucasian population. Invest Ophthalmol Vis Sci (2011) 1.23

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. Nat Genet (2014) 1.13

Common variants in CDKN2B-AS1 associated with optic-nerve vulnerability of glaucoma identified by genome-wide association studies in Japanese. PLoS One (2012) 1.10

Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry. Invest Ophthalmol Vis Sci (2013) 1.10

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma. Nat Genet (2016) 1.02

Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma. Nat Genet (2014) 1.00

Genome-wide association study and meta-analysis of intraocular pressure. Hum Genet (2013) 0.98

Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma. Nat Genet (2014) 0.97

Corneal thickness. II. Environmental and genetic factors. Acta Ophthalmol (Copenh) (1978) 0.95

The genetic determination of ocular pressure in the normal eye. Arch Ophthalmol (1967) 0.95

Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology. Genet Epidemiol (2015) 0.92

A common variant near TGFBR3 is associated with primary open angle glaucoma. Hum Mol Genet (2015) 0.91

Association between SRBD1 and ELOVL5 gene polymorphisms and primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2011) 0.89

Association of Toll-like receptor 4 gene polymorphisms in Japanese subjects with primary open-angle, normal-tension, and exfoliation glaucoma. Am J Ophthalmol (2012) 0.88

Association between genetic variants associated with vertical cup-to-disc ratio and phenotypic features of primary open-angle glaucoma. Ophthalmology (2012) 0.88

Linkage and association analyses of glaucoma related traits in a large pedigree from a Dutch genetically isolated population. J Med Genet (2011) 0.85

Toll-like receptor 4 gene polymorphisms do not associate with normal tension glaucoma in a Korean population. Mol Vis (2011) 0.81

Association of open-angle glaucoma loci with incident glaucoma in the Blue Mountains Eye Study. Am J Ophthalmol (2014) 0.79

Analysis of toll-like receptor rs4986790 polymorphism in Saudi patients with primary open angle glaucoma. Ophthalmic Genet (2016) 0.76