Pre-transplantation novel agent induction predicts progression-free survival for patients with immunoglobulin light-chain amyloidosis undergoing high-dose melphalan and autologous stem cell transplantation.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27879147)

Published in Amyloid on November 23, 2016

Authors

Andrew J Cowan1,2, Zandra K Klippel3, Philip A Stevenson2, Teresa S Hyun2,4, Sherilyn Tuazon1,2, Pamela S Becker2,5, Damian J Green1,2, Leona A Holmberg1,2, David G Coffey1,2, Ajay K Gopal1,2, Edward N Libby1,2

Author Affiliations

1: a Division of Medical Oncology , University of Washington , Seattle , WA , USA.
2: b Clinical Research Division, Fred Hutchinson Cancer Research Center , Seattle , WA , USA.
3: c Hematology/Oncology, Amgen Inc. , Thousand Oaks , CA , USA.
4: d Department of Pathology , University of Washington , Seattle , WA , USA , and.
5: e Division of Hematology , Department of Medicine, University of Washington , Seattle , WA , USA.

Articles cited by this

High-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis. N Engl J Med (2007) 5.84

Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): a consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis, Tours, France, 18-22 April 2004. Am J Hematol (2005) 5.64

International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol (2014) 4.37

High-dose melphalan and autologous stem-cell transplantation in patients with AL amyloidosis: an 8-year study. Ann Intern Med (2004) 4.05

Lenalidomide and dexamethasone in the treatment of AL amyloidosis: results of a phase 2 trial. Blood (2006) 2.97

Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients. Blood (2011) 2.72

Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway. Proc Natl Acad Sci U S A (2010) 2.41

Human amyloidogenic light chains directly impair cardiomyocyte function through an increase in cellular oxidant stress. Circ Res (2004) 2.25

Achievement of at least very good partial response is a simple and robust prognostic factor in patients with multiple myeloma treated with high-dose therapy: long-term analysis of the IFM 99-02 and 99-04 Trials. J Clin Oncol (2009) 1.69

Consensus guidelines for the conduct and reporting of clinical trials in systemic light-chain amyloidosis. Leukemia (2012) 1.60

Clinical aspects of systemic amyloid diseases. Biochim Biophys Acta (2005) 1.58

Induction Therapy with Bortezomib Followed by Bortezomib-High Dose Melphalan and Stem Cell Transplantation for Light Chain Amyloidosis: Results of a Prospective Clinical Trial. Biol Blood Marrow Transplant (2015) 1.56

How I treat amyloidosis. Blood (2009) 1.16

Systemic and microvascular oxidative stress induced by light chain amyloidosis. Int J Cardiol (2009) 1.13

High-dose melphalan with autologous stem cell transplantation after VAD induction chemotherapy for treatment of amyloid light chain amyloidosis: a single centre prospective phase II study. Br J Haematol (2004) 1.11

Cellular response of cardiac fibroblasts to amyloidogenic light chains. Am J Pathol (2005) 1.02

Cytotoxicity of amyloidogenic immunoglobulin light chains in cell culture. Cell Death Dis (2010) 1.00

Induction therapy with bortezomib and dexamethasone followed by autologous stem cell transplantation versus autologous stem cell transplantation alone in the treatment of renal AL amyloidosis: a randomized controlled trial. BMC Med (2014) 0.91

High-dose intravenous melphalan and autologous stem cell transplantation as initial therapy or following two cycles of oral chemotherapy for the treatment of AL amyloidosis: results of a prospective randomized trial. Bone Marrow Transplant (2004) 0.84

Modified high-dose melphalan and autologous SCT for AL amyloidosis or high-risk myeloma: analysis of SWOG trial S0115. Bone Marrow Transplant (2013) 0.80

The Effect of Bone Marrow Plasma Cell Burden on Survival in Patients with Light Chain Amyloidosis Undergoing High-Dose Melphalan and Autologous Stem Cell Transplantation. Biol Blood Marrow Transplant (2016) 0.79