Isolation and direct complete nucleotide determination of entire genes. Characterization of a gene coding for 16S ribosomal RNA.

PubWeight™: 19.85‹?› | Rank: Top 0.1% | All-Time Top 10000

🔗 View Article (PMC 334891)

Published in Nucleic Acids Res on October 11, 1989

Authors

U Edwards1, T Rogall, H Blöcker, M Emde, E C Böttger

Author Affiliations

1: Institut für Medizinische Mikrobiologie, Medizinische Hochschule Hannover, FRG.

Articles citing this

(truncated to the top 100)

16S ribosomal DNA amplification for phylogenetic study. J Bacteriol (1991) 47.78

Development of the human infant intestinal microbiota. PLoS Biol (2007) 18.91

Detection and identification of mycobacteria by amplification of rRNA. J Clin Microbiol (1990) 12.41

Compilation of small ribosomal subunit RNA sequences. Nucleic Acids Res (1990) 11.22

Genotypic identification of mycobacteria by nucleic acid sequence determination: report of a 2-year experience in a clinical laboratory. J Clin Microbiol (1993) 9.76

Molecular analysis of human forearm superficial skin bacterial biota. Proc Natl Acad Sci U S A (2007) 9.73

Levels of bacterial community diversity in four arid soils compared by cultivation and 16S rRNA gene cloning. Appl Environ Microbiol (1999) 9.59

Impact of 16S rRNA gene sequence analysis for identification of bacteria on clinical microbiology and infectious diseases. Clin Microbiol Rev (2004) 7.95

Bacterial diversity within the human subgingival crevice. Proc Natl Acad Sci U S A (1999) 7.86

Dissecting biological "dark matter" with single-cell genetic analysis of rare and uncultivated TM7 microbes from the human mouth. Proc Natl Acad Sci U S A (2007) 7.82

Diverse uncultivated bacterial groups from soils of the arid southwestern United States that are present in many geographic regions. Appl Environ Microbiol (1997) 7.05

Specific amplification of 18S fungal ribosomal genes from vesicular-arbuscular endomycorrhizal fungi colonizing roots. Appl Environ Microbiol (1992) 5.21

Microbes on the human vaginal epithelium. Proc Natl Acad Sci U S A (2005) 5.15

Compilation of small ribosomal subunit RNA sequences. Nucleic Acids Res (1991) 5.03

Analysis of ammonia-oxidizing bacteria of the beta subdivision of the class Proteobacteria in coastal sand dunes by denaturing gradient gel electrophoresis and sequencing of PCR-amplified 16S ribosomal DNA fragments. Appl Environ Microbiol (1997) 5.01

Necessity of quality-controlled 16S rRNA gene sequence databases: identifying nontuberculous Mycobacterium species. J Clin Microbiol (2001) 4.63

Molecular diagnosis of bacterial endocarditis by broad-range PCR amplification and direct sequencing. J Clin Microbiol (1997) 4.20

Assessment of microbial diversity in four southwestern United States soils by 16S rRNA gene terminal restriction fragment analysis. Appl Environ Microbiol (2000) 4.12

Phylogenetic specificity and reproducibility and new method for analysis of terminal restriction fragment profiles of 16S rRNA genes from bacterial communities. Appl Environ Microbiol (2001) 4.01

Wide distribution and diversity of members of the bacterial kingdom Acidobacterium in the environment. Appl Environ Microbiol (1999) 3.89

Substantial alterations of the cutaneous bacterial biota in psoriatic lesions. PLoS One (2008) 3.56

PCR amplification and direct sequencing of gyrB genes with universal primers and their application to the detection and taxonomic analysis of Pseudomonas putida strains. Appl Environ Microbiol (1995) 3.52

Isolation and identification of methanogen-specific DNA from blanket bog peat by PCR amplification and sequence analysis. Appl Environ Microbiol (1996) 3.47

Bacterial diversity in the oral cavity of 10 healthy individuals. ISME J (2010) 3.39

Identification of Mycobacterium species by using amplified ribosomal DNA restriction analysis. J Clin Microbiol (1993) 3.38

Elimination of contaminating DNA within polymerase chain reaction reagents: implications for a general approach to detection of uncultured pathogens. J Clin Microbiol (1993) 3.22

How stable is stable? Function versus community composition. Appl Environ Microbiol (1999) 3.08

Development of a universal microarray based on the ligation detection reaction and 16S rrna gene polymorphism to target diversity of cyanobacteria. Appl Environ Microbiol (2004) 3.05

Rapid quantitative profiling of complex microbial populations. Nucleic Acids Res (2006) 2.75

Amplification of DNA from native populations of soil bacteria by using the polymerase chain reaction. Appl Environ Microbiol (1992) 2.73

Isolation and characterization of a unique group of slowly growing mycobacteria: description of Mycobacterium lentiflavum sp. nov. J Clin Microbiol (1996) 2.66

Differentiation of Mycobacterium ulcerans, M. marinum, and M. haemophilum: mapping of their relationships to M. tuberculosis by fatty acid profile analysis, DNA-DNA hybridization, and 16S rRNA gene sequence analysis. J Clin Microbiol (1998) 2.58

The human vaginal bacterial biota and bacterial vaginosis. Interdiscip Perspect Infect Dis (2009) 2.56

Formation of pseudo-terminal restriction fragments, a PCR-related bias affecting terminal restriction fragment length polymorphism analysis of microbial community structure. Appl Environ Microbiol (2003) 2.46

Analysis of streptococcal CRISPRs from human saliva reveals substantial sequence diversity within and between subjects over time. Genome Res (2010) 2.46

Phylogenetic evidence for the early evolution of microcystin synthesis. Proc Natl Acad Sci U S A (2003) 2.46

Environmental biodiversity, human microbiota, and allergy are interrelated. Proc Natl Acad Sci U S A (2012) 2.41

Genetic heterogeneity within Mycobacterium fortuitum complex species: genotypic criteria for identification. J Clin Microbiol (1992) 2.30

The human intestinal microbiome: a new frontier of human biology. DNA Res (2009) 2.30

Nearly finished genomes produced using gel microdroplet culturing reveal substantial intraspecies genomic diversity within the human microbiome. Genome Res (2013) 2.29

Identification of mycobacteria from animals by restriction enzyme analysis and direct DNA cycle sequencing of polymerase chain reaction-amplified 16S rRNA gene sequences. J Clin Microbiol (1993) 2.28

Diversity and seasonal dynamics of bacterial community in indoor environment. BMC Microbiol (2008) 2.22

Comparison of diversities and compositions of bacterial populations inhabiting natural forest soils. Appl Environ Microbiol (2004) 2.21

Influence of Arabidopsis thaliana accessions on rhizobacterial communities and natural variation in root exudates. J Exp Bot (2009) 2.15

Measurement of rRNA Variations in Natural Communities of Microorganisms on the Southeastern U.S. Continental Shelf. Appl Environ Microbiol (1993) 2.14

Characterization of an SAV organism and proposal of Mycobacterium triplex sp. nov. J Clin Microbiol (1996) 2.09

Ribosomal DNA sequencing for identification of aerobic gram-positive rods in the clinical laboratory (an 18-month evaluation). J Clin Microbiol (2003) 2.02

Molecular analysis of ammonia-oxidizing bacteria of the beta subdivision of the class Proteobacteria in compost and composted materials. Appl Environ Microbiol (1999) 2.00

Comparison of soil bacterial communities in rhizospheres of three plant species and the interspaces in an arid grassland. Appl Environ Microbiol (2002) 1.98

Methods for microbial DNA extraction from soil for PCR amplification. Biol Proced Online (1998) 1.95

DNA/DNA hybridization to microarrays reveals gene-specific differences between closely related microbial genomes. Proc Natl Acad Sci U S A (2001) 1.90

Distinct distal gut microbiome diversity and composition in healthy children from Bangladesh and the United States. PLoS One (2013) 1.86

Microbial community structure in midgut and hindgut of the humus-feeding larva of Pachnoda ephippiata (Coleoptera: Scarabaeidae). Appl Environ Microbiol (2003) 1.83

Laboratory aspects of "Mycobacterium genavense," a proposed species isolated from AIDS patients. J Clin Microbiol (1992) 1.82

Phylogenetic diversity, abundance, and axial distribution of bacteria in the intestinal tract of two soil-feeding termites (Cubitermes spp.). Appl Environ Microbiol (2003) 1.77

Simultaneous amplicon sequencing to explore co-occurrence patterns of bacterial, archaeal and eukaryotic microorganisms in rumen microbial communities. PLoS One (2013) 1.77

Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers. BMC Gastroenterol (2009) 1.76

The ultramicrobacterium "Elusimicrobium minutum" gen. nov., sp. nov., the first cultivated representative of the termite group 1 phylum. Appl Environ Microbiol (2009) 1.76

Mycobacterium interjectum, a new species isolated from a patient with chronic lymphadenitis. J Clin Microbiol (1993) 1.73

Variations in rRNA content of marine Vibrio spp. during starvation-survival and recovery. Appl Environ Microbiol (1992) 1.69

Abiotrophia elegans sp. nov., a possible pathogen in patients with culture-negative endocarditis. J Clin Microbiol (1998) 1.68

Streptococcus pseudoporcinus sp. nov., a novel species isolated from the genitourinary tract of women. J Clin Microbiol (2006) 1.62

Molecular basis of AmpC hyperproduction in clinical isolates of Escherichia coli. Antimicrob Agents Chemother (1999) 1.62

Diagnostic assay for Helicobacter hepaticus based on nucleotide sequence of its 16S rRNA gene. J Clin Microbiol (1995) 1.60

Methicillin-resistant Staphylococcus aureus (MRSA) detected at four U.S. wastewater treatment plants. Environ Health Perspect (2012) 1.60

Molecular analysis of sarcoidosis tissues for mycobacterium species DNA. Emerg Infect Dis (2002) 1.59

The intestinal microbiota plays a role in Salmonella-induced colitis independent of pathogen colonization. PLoS One (2011) 1.57

Global dispersion of bacterial cells on Asian dust. Sci Rep (2012) 1.56

Response of endophytic bacterial communities in potato plants to infection with Erwinia carotovora subsp. atroseptica. Appl Environ Microbiol (2002) 1.54

Succession and convergence of biofilm communities in fixed-film reactors treating aromatic hydrocarbons in groundwater. Appl Environ Microbiol (1997) 1.52

A new agent of mycobacterial lymphadenitis in children: Mycobacterium heidelbergense sp. nov. J Clin Microbiol (1997) 1.52

Assessment of mycobacterial viability by RNA amplification. Antimicrob Agents Chemother (1994) 1.51

Mycobacteriosis due to Mycobacterium genavense in six pet birds. J Clin Microbiol (1993) 1.49

Robust hydrocarbon degradation and dynamics of bacterial communities during nutrient-enhanced oil spill bioremediation. Appl Environ Microbiol (2002) 1.49

Helicobacter sp. strain Mainz isolated from an AIDS patient with septic arthritis: case report and nonradioactive analysis of 16S rRNA sequence. J Clin Microbiol (1994) 1.45

Bacterial microbiota profiling in gastritis without Helicobacter pylori infection or non-steroidal anti-inflammatory drug use. PLoS One (2009) 1.44

Soil and sediment bacteria capable of aerobic nitrate respiration. Appl Environ Microbiol (1995) 1.44

Halotolerant aerobic heterotrophic bacteria from the Great Salt Plains of Oklahoma. Microb Ecol (2004) 1.43

Bacterial communities associated with flowering plants of the Ni hyperaccumulator Thlaspi goesingense. Appl Environ Microbiol (2004) 1.43

Bacterial community dynamics and hydrocarbon degradation during a field-scale evaluation of bioremediation on a mudflat beach contaminated with buried oil. Appl Environ Microbiol (2004) 1.42

Stable-isotope probing of bacteria capable of degrading salicylate, naphthalene, or phenanthrene in a bioreactor treating contaminated soil. Appl Environ Microbiol (2005) 1.41

Correlating microbial community profiles with geochemical data in highly stratified sediments from the Arctic Mid-Ocean Ridge. Proc Natl Acad Sci U S A (2012) 1.37

Phylogenetic analysis of bacterial communities in mesophilic and thermophilic bioreactors treating pharmaceutical wastewater. Appl Environ Microbiol (2000) 1.37

Random amplified polymorphic DNA typing versus pulsed-field gel electrophoresis for epidemiological typing of vancomycin-resistant enterococci. J Clin Microbiol (1996) 1.35

Endophytic bacterial diversity in rice (Oryza sativa L.) roots estimated by 16S rDNA sequence analysis. Microb Ecol (2007) 1.32

Clinically applicable multiplex PCR for four middle ear pathogens. J Clin Microbiol (2000) 1.32

Endophytes of grapevine flowers, berries, and seeds: identification of cultivable bacteria, comparison with other plant parts, and visualization of niches of colonization. Microb Ecol (2011) 1.32

Detection of microcystin-producing cyanobacteria in Finnish lakes with genus-specific microcystin synthetase gene E (mcyE) PCR and associations with environmental factors. Appl Environ Microbiol (2006) 1.30

Long-term phosphorus fertilization impacts soil fungal and bacterial diversity but not AM fungal community in alfalfa. Microb Ecol (2009) 1.29

Links between plant and rhizoplane bacterial communities in grassland soils, characterized using molecular techniques. Appl Environ Microbiol (2005) 1.29

The quantitative significance of Syntrophaceae and syntrophic partnerships in methanogenic degradation of crude oil alkanes. Environ Microbiol (2011) 1.29

Incidence of class 1 integrons in a quaternary ammonium compound-polluted environment. Antimicrob Agents Chemother (2005) 1.28

Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. Antimicrob Agents Chemother (2008) 1.28

Next generation sequencing to define prokaryotic and fungal diversity in the bovine rumen. PLoS One (2012) 1.27

In situ transfer of antibiotic resistance genes from transgenic (transplastomic) tobacco plants to bacteria. Appl Environ Microbiol (2002) 1.27

Community structure of ammonia-oxidizing bacteria within anoxic marine sediments. Appl Environ Microbiol (2003) 1.27

The Dehalococcoides population in sediment-free mixed cultures metabolically dechlorinates the commercial polychlorinated biphenyl mixture aroclor 1260. Appl Environ Microbiol (2007) 1.26

Distinct and diverse anaerobic bacterial communities in boreal lakes dominated by candidate division OD1. ISME J (2012) 1.26

Helicobacter pylori: clonal population structure and restricted transmission within families revealed by molecular typing. J Clin Microbiol (2000) 1.25

Cross-kingdom amplification using bacteria-specific primers: complications for studies of coral microbial ecology. Appl Environ Microbiol (2008) 1.25

Articles cited by this

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science (1988) 220.77

Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science (1985) 95.08

Bacterial evolution. Microbiol Rev (1987) 85.63

Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol (1987) 58.68

Rapid determination of 16S ribosomal RNA sequences for phylogenetic analyses. Proc Natl Acad Sci U S A (1985) 37.69

A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res (1988) 26.70

Phylogenetic stains: ribosomal RNA-based probes for the identification of single cells. Science (1989) 24.75

Phylogenetic group-specific oligodeoxynucleotide probes for identification of single microbial cells. J Bacteriol (1988) 21.38

Direct cloning and sequence analysis of enzymatically amplified genomic sequences. Science (1986) 19.54

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus. Proc Natl Acad Sci U S A (1988) 18.72

DNA sequencing with Thermus aquaticus DNA polymerase and direct sequencing of polymerase chain reaction-amplified DNA. Proc Natl Acad Sci U S A (1988) 14.20

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature (1987) 10.70

Length mutations in human mitochondrial DNA: direct sequencing of enzymatically amplified DNA. Nucleic Acids Res (1987) 10.38

Characterization of beta-thalassaemia mutations using direct genomic sequencing of amplified single copy DNA. Nature (1987) 8.58

Compilation of small ribosomal subunit RNA sequences. Nucleic Acids Res (1988) 5.85

On the evolutionary descent of organisms and organelles: a global phylogeny based on a highly conserved structural core in small subunit ribosomal RNA. Nucleic Acids Res (1984) 5.54

Polymerase chain reaction reveals cloning artefacts. Nature (1988) 4.76

Complete nucleotide sequence of the 16S rRNA gene of Mycobacterium bovis BCG. J Bacteriol (1988) 4.10

Errors in the polymerase chain reaction. Nucleic Acids Res (1988) 3.52

Species-specific oligonucleotide probes for rRNA of Clostridium difficile and related species. J Clin Microbiol (1988) 2.87

Synthetic oligonucleotide probes complementary to rRNA for group- and species-specific detection of mycoplasmas. Isr J Med Sci (1987) 2.76

Direct sequencing of polymerase chain reaction amplified DNA fragments through the incorporation of deoxynucleoside alpha-thiotriphosphates. Nucleic Acids Res (1988) 2.28

Rapid ribosomal RNA sequencing and the phylogenetic analysis of protists. Parasitol Today (1989) 1.50

Articles by these authors

Initial sequencing and analysis of the human genome. Nature (2001) 212.86

Predicting DNA duplex stability from the base sequence. Proc Natl Acad Sci U S A (1986) 21.73

Rapid identification of mycobacteria to the species level by polymerase chain reaction and restriction enzyme analysis. J Clin Microbiol (1993) 18.91

Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector. Gene (1986) 13.92

Detection and identification of mycobacteria by amplification of rRNA. J Clin Microbiol (1990) 12.41

Genotypic identification of mycobacteria by nucleic acid sequence determination: report of a 2-year experience in a clinical laboratory. J Clin Microbiol (1993) 9.76

Towards a phylogeny and definition of species at the molecular level within the genus Mycobacterium. Int J Syst Bacteriol (1990) 7.65

Differentiation of Mycobacterium species by direct sequencing of amplified DNA. J Gen Microbiol (1990) 7.33

Two-laboratory collaborative study on identification of mycobacteria: molecular versus phenotypic methods. J Clin Microbiol (1996) 5.80

Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature (1999) 5.03

Genome sequence, comparative analysis, and population genetics of the domestic horse. Science (2009) 4.41

DNA sequence and comparative analysis of chimpanzee chromosome 22. Nature (2004) 4.12

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. Genome Res (2001) 3.97

Molecular basis of streptomycin resistance in Mycobacterium tuberculosis: alterations of the ribosomal protein S12 gene and point mutations within a functional 16S ribosomal RNA pseudoknot. Mol Microbiol (1993) 3.83

Brief report: disseminated osteomyelitis from Mycobacterium ulcerans after a snakebite. N Engl J Med (1993) 3.75

Inducible expression vectors incorporating the Escherichia coli atpE translational initiation region. Gene (1987) 3.46

Identification of mutations in 23S rRNA gene of clarithromycin-resistant Mycobacterium intracellulare. Antimicrob Agents Chemother (1994) 3.28

16S rRNA gene sequencing versus the API 20 NE system and the VITEK 2 ID-GNB card for identification of nonfermenting Gram-negative bacteria in the clinical laboratory. J Clin Microbiol (2006) 3.25

Elimination of contaminating DNA within polymerase chain reaction reagents: implications for a general approach to detection of uncultured pathogens. J Clin Microbiol (1993) 3.22

Microheterogeneity within rRNA of Mycobacterium gordonae. J Clin Microbiol (1992) 3.20

Mycobacterium wolinskyi sp. nov. and Mycobacterium goodii sp. nov., two new rapidly growing species related to Mycobacterium smegmatis and associated with human wound infections: a cooperative study from the International Working Group on Mycobacterial Taxonomy. Int J Syst Bacteriol (1999) 3.16

Genetic basis for clarithromycin resistance among isolates of Mycobacterium chelonae and Mycobacterium abscessus. Antimicrob Agents Chemother (1996) 2.92

Isolation and characterization of a unique group of slowly growing mycobacteria: description of Mycobacterium lentiflavum sp. nov. J Clin Microbiol (1996) 2.66

Phylogeny of the Mycobacterium chelonae-like organism based on partial sequencing of the 16S rRNA gene and proposal of Mycobacterium mucogenicum sp. nov. Int J Syst Bacteriol (1995) 2.50

rpsL+: a dominant selectable marker for gene replacement in mycobacteria. Mol Microbiol (1995) 2.49

A new general approach for the simultaneous chemical synthesis of large numbers of oligonucleotides: segmental solid supports. Nucleic Acids Res (1983) 2.48

Phylogenetic analysis and identification of different serovars of Mycobacterium intracellulare at the molecular level. FEMS Microbiol Lett (1990) 2.47

Mycobacterium immunogenum sp. nov., a novel species related to Mycobacterium abscessus and associated with clinical disease, pseudo-outbreaks and contaminated metalworking fluids: an international cooperative study on mycobacterial taxonomy. Int J Syst Evol Microbiol (2001) 2.38

A single 16S ribosomal RNA substitution is responsible for resistance to amikacin and other 2-deoxystreptamine aminoglycosides in Mycobacterium abscessus and Mycobacterium chelonae. J Infect Dis (1998) 2.34

Genetic heterogeneity within Mycobacterium fortuitum complex species: genotypic criteria for identification. J Clin Microbiol (1992) 2.30

Heterogeneity and clonality among isolates of Mycobacterium kansasii: implications for epidemiological and pathogenicity studies. J Clin Microbiol (1997) 2.24

Frequent contamination of Taq polymerase with DNA. Clin Chem (1990) 2.23

Genetic alterations in streptomycin-resistant Mycobacterium tuberculosis: mapping of mutations conferring resistance. Antimicrob Agents Chemother (1994) 2.23

Identification of mycobacteria by PCR-based sequence determination of the 32-kilodalton protein gene. J Clin Microbiol (1994) 2.20

Species identification of mycobacteria using rDNA sequencing. Methods Mol Biol (1998) 2.19

Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Nature (2000) 2.17

Ribosomal DNA sequencing for identification of aerobic gram-positive rods in the clinical laboratory (an 18-month evaluation). J Clin Microbiol (2003) 2.02

Semantide- and chemotaxonomy-based analyses of some problematic phenotypic clusters of slowly growing mycobacteria, a cooperative study of the International Working Group on Mycobacterial Taxonomy. Int J Syst Bacteriol (1996) 2.02

Comparison of conventional and molecular methods for identification of aerobic catalase-negative gram-positive cocci in the clinical laboratory. J Clin Microbiol (2004) 1.96

Diagnosis of mycobacterial infections by nucleic acid amplification: 18-month prospective study. J Clin Microbiol (1996) 1.94

Fitness of antibiotic-resistant microorganisms and compensatory mutations. Nat Med (1998) 1.94

The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. Nature (1997) 1.92

Laboratory aspects of "Mycobacterium genavense," a proposed species isolated from AIDS patients. J Clin Microbiol (1992) 1.82

Burden of unidentifiable mycobacteria in a reference laboratory. J Clin Microbiol (2001) 1.79

Mycobacterium lentiflavum: an etiologic agent of cervical lymphadenitis. Clin Infect Dis (1997) 1.79

Mycobacterium intermedium sp. nov. Int J Syst Bacteriol (1993) 1.75

Transgenic mice selectively lacking MHC class II (I-E) antigen expression on B cells: an in vivo approach to investigate Ia gene function. Cell (1987) 1.74

Mycobacterium interjectum, a new species isolated from a patient with chronic lymphadenitis. J Clin Microbiol (1993) 1.73

Mycobacterium branderi sp. nov., a new potential human pathogen. Int J Syst Bacteriol (1995) 1.71

Analysis of cytokine mRNA levels in interleukin-4-transgenic mice by quantitative polymerase chain reaction. Eur J Immunol (1992) 1.67

Lipoprotein processing is required for virulence of Mycobacterium tuberculosis. Mol Microbiol (2004) 1.67

Introducing mutations into a chromosomal rRNA gene using a genetically modified eubacterial host with a single rRNA operon. Mol Microbiol (1996) 1.65

Ribosomal and non-ribosomal resistance to oxazolidinones: species-specific idiosyncrasy of ribosomal alterations. Mol Microbiol (2002) 1.64

Characterization of mycobacterial isolates phylogenetically related to, but different from Mycobacterium simiae. J Clin Microbiol (1997) 1.64

Molecular mechanisms of clarithromycin resistance in Mycobacterium avium: observation of multiple 23S rDNA mutations in a clonal population. J Infect Dis (1996) 1.61

Species-specific assessment of Mycobacterium leprae in skin biopsies by in situ hybridization and polymerase chain reaction. Lab Invest (1992) 1.55

Lack of rifabutin resistance with prophylaxis for disseminated Mycobacterium avium complex. Lancet (1994) 1.55

The role of ribosomal RNAs in macrolide resistance. Mol Microbiol (1997) 1.53

Crystal structure analysis of an A-DNA fragment at 1.8 A resolution: d(GCCCGGGC). Nucleic Acids Res (1987) 1.53

Ultrafast sequencing of oligodeoxyribonucleotides by FAB-mass spectrometry. Nucleic Acids Res (1982) 1.53

A new agent of mycobacterial lymphadenitis in children: Mycobacterium heidelbergense sp. nov. J Clin Microbiol (1997) 1.52

Mycobacterium tuberculosis nucleic acid probes for rapid diagnosis. Lancet (1993) 1.51

Correlation of molecular resistance mechanisms and phenotypic resistance levels in streptomycin-resistant Mycobacterium tuberculosis. Antimicrob Agents Chemother (1996) 1.51

RecA-Mediated gene conversion and aminoglycoside resistance in strains heterozygous for rRNA. Antimicrob Agents Chemother (1999) 1.51

Genetic interrelationships of proteolytic Clostridium botulinum types A, B, and F and other members of the Clostridium botulinum complex as revealed by small-subunit rRNA gene sequences. Antonie Van Leeuwenhoek (1994) 1.50

Mycobacteriosis due to Mycobacterium genavense in six pet birds. J Clin Microbiol (1993) 1.49

New lessons for combinatorial biosynthesis from myxobacteria. The myxothiazol biosynthetic gene cluster of Stigmatella aurantiaca DW4/3-1. J Biol Chem (1999) 1.49

Mechanisms of streptomycin resistance: selection of mutations in the 16S rRNA gene conferring resistance. Antimicrob Agents Chemother (2001) 1.46

Gin-mediated site-specific recombination in bacteriophage Mu DNA: overproduction of the protein and inversion in vitro. EMBO J (1984) 1.41

Mycobacterium conspicuum sp. nov., a new species isolated from patients with disseminated infections. J Clin Microbiol (1995) 1.41

Instability and site-specific excision of integration-proficient mycobacteriophage L5 plasmids: development of stably maintained integrative vectors. Int J Med Microbiol (2001) 1.40

Recovery of mycobacteria from patients with cystic fibrosis. J Clin Microbiol (1999) 1.37

Internal transcribed spacer sequencing versus biochemical profiling for identification of medically important yeasts. J Clin Microbiol (2006) 1.37

Cervical lymphadenitis in a child caused by a previously unknown mycobacterium. J Infect Dis (1993) 1.35

Role of thymidine residues in DNA recognition by the EcoRI and EcoRV restriction endonucleases. Nucleic Acids Res (1986) 1.34

Mutagenesis of 16S rRNA C1409-G1491 base-pair differentiates between 6'OH and 6'NH3+ aminoglycosides. J Mol Biol (2004) 1.32

Novel features in a combined polyketide synthase/non-ribosomal peptide synthetase: the myxalamid biosynthetic gene cluster of the myxobacterium Stigmatella aurantiaca Sga15. Chem Biol (2001) 1.26

The 16S rRNA nucleotide sequence of Mycobacterium leprae: phylogenetic position and development of DNA probes. FEMS Microbiol Lett (1991) 1.25

Evaluation of the colorimetric VITEK 2 card for identification of gram-negative nonfermentative rods: comparison to 16S rRNA gene sequencing. J Clin Microbiol (2007) 1.23

Mycobacterium confluentis sp. nov. Int J Syst Bacteriol (1992) 1.23

Role of 16S rRNA Helix 44 in Ribosomal Resistance to Hygromycin B. Antimicrob Agents Chemother (2003) 1.22

Mycobacterium bovis BCG recA deletion mutant shows increased susceptibility to DNA-damaging agents but wild-type survival in a mouse infection model. Infect Immun (2001) 1.22

DNA sequence and analysis of human chromosome 9. Nature (2004) 1.21

Phospholipid-hydroperoxide glutathione peroxidase. Genomic DNA, cDNA, and deduced amino acid sequence. J Biol Chem (1994) 1.20

Isolation of an unusual mycobacterium from an AIDS patient. J Clin Microbiol (1996) 1.19

Investigation of the tertiary folding of Escherichia coli 16S RNA by in situ intra-RNA cross-linking within 30S ribosomal subunits. Nucleic Acids Res (1985) 1.16

Expression of the chemically synthesized gene for ribonuclease T1 in Escherichia coli using a secretion cloning vector. Eur J Biochem (1988) 1.15

Cervical lymphadenitis due to an unusual mycobacterium. Eur J Clin Microbiol Infect Dis (1997) 1.14

Cloning, sequencing and expression in Escherichia coli of the D-2-hydroxyisocaproate dehydrogenase gene of Lactobacillus casei. Gene (1989) 1.14

Lack of transmission of mycobacterium abscessus among patients with cystic fibrosis attending a single clinic. Clin Infect Dis (2001) 1.14

Invasive infection with Mycobacterium genavense in three children with the acquired immunodeficiency syndrome. Eur J Clin Microbiol Infect Dis (1993) 1.13

A genetic model to investigate drug-target interactions at the ribosomal decoding site. Biochimie (2006) 1.13

The complete nucleotide sequence of the egg drop syndrome virus: an intermediate between mastadenoviruses and aviadenoviruses. Virology (1997) 1.13

Cloning, sequencing and expression of a sialidase gene from Clostridium sordellii G12. J Gen Microbiol (1989) 1.12

Mycobacterium tuberculosis population structure determines the outcome of genetics-based second-line drug resistance testing. Antimicrob Agents Chemother (2012) 1.12

Site-specific recombination in bacteriophage Mu: characterization of binding sites for the DNA invertase Gin. EMBO J (1988) 1.12

The 5'-terminal sequence of U1 RNA complementary to the consensus 5' splice site of hnRNA is single-stranded in intact U1 snRNP particles. Nucleic Acids Res (1984) 1.11

The critical influence of the intermediate category on interpretation errors in revised EUCAST and CLSI antimicrobial susceptibility testing guidelines. Clin Microbiol Infect (2012) 1.09