Infiltration of PD-1-positive cells in combination with tumor site PD-L1 expression is a positive prognostic factor in cutaneous angiosarcoma.

PubWeight™: 0.78‹?›

🔗 View Article (PMID 28197370)

Published in Oncoimmunology on November 04, 2016

Authors

Yuki Honda1, Atsushi Otsuka1, Sachiko Ono1, Yosuke Yamamoto1, Judith A Seidel1, Satoshi Morita2, Masahiro Hirata3, Tatsuki R Kataoka3, Tatsuya Takenouchi4, Kazuyasu Fujii5, Takuro Kanekura5, Yuko Okubo6, Kenzo Takahashi6, Teruki Yanagi7, Daichi Hoshina7, Hiroo Hata7, Riichiro Abe8, Taku Fujimura9, Takeru Funakoshi9, Koji Yoshino10, Mamiko Masuzawa11, Yasuyuki Amoh12, Ryota Tanaka12, Yasuhiro Fujisawa13, Tetsuya Honda1, Kenji Kabashima1

Author Affiliations

1: Department of Dermatology, Kyoto University Graduate School of Medicine , Sakyo-ku, Kyoto, Japan.
2: Department of Biomedical Statistics and Bioinformatics, Kyoto University Graduate School of Medicine , Sakyo-ku, Kyoto, Japan.
3: Department of Diagnostic Pathology, Kyoto University Graduate School of Medicine , Sakyo-ku, Kyoto, Japan.
4: Department of Dermatology, Niigata Cancer Center Hospital , Chuo-ku, Niigata, Japan.
5: Department of Dermatology, Kagoshima University Faculty of Medicine , Sakuragaoka, Kagoshima, Japan.
6: Department of Dermatology, University of the Ryukyus , Nishihara, Okinawa, Japan.
7: Department of Dermatology, Hokkaido University Graduate School of Medicine , Kita-ku, Sapporo, Japan.
8: Division of Dermatology, Niigata University Graduate School of Medicine and Dental Sciences , Chuo-ku, Niigata, Japan.
9: Department of Dermatology, Tohoku University Graduate School of Medicine , Aoba-ku, Miyagi, Japan.
10: Department of Dermatology, Keio University School of Medicine , Shinjyuku-ku, Tokyo, Japan.
11: Department of Dermatology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital , Bunkyo-ku, Tokyo, Japan.
12: Department of Dermatology, Kitasato University School of Medicine , Minami-ku, Sagamihara, Japan.
13: Department of Dermatology, University of Tsukuba , Tsukuba, Japan.

Articles cited by this

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med (2012) 52.99

Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Sci Transl Med (2012) 13.12

PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma. N Engl J Med (2014) 10.10

Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer. Proc Natl Acad Sci U S A (2007) 7.49

Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma. Nat Med (2006) 7.10

Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial. Lancet Oncol (2015) 5.95

PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells. Cancer Res (2004) 5.59

Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma. Cancer (2010) 5.05

Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer. Clin Cancer Res (2005) 4.42

Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer. Clin Cancer Res (2007) 4.41

PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma. Clin Cancer Res (2007) 3.23

Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas: a study of 1240 patients from the French Federation of Cancer Centers Sarcoma Group. Cancer (2001) 2.85

Phase II trial of weekly paclitaxel for unresectable angiosarcoma: the ANGIOTAX Study. J Clin Oncol (2008) 2.85

Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1. J Exp Med (2009) 2.73

A 14-year retrospective review of angiosarcoma: clinical characteristics, prognostic factors, and treatment outcomes with surgery and chemotherapy. Cancer J (2005) 2.71

Expression and regulation of the PD-L1 immunoinhibitory molecule on microvascular endothelial cells. Microcirculation (2002) 2.49

PD-1-expressing tumor-infiltrating T cells are a favorable prognostic biomarker in HPV-associated head and neck cancer. Cancer Res (2012) 2.43

PD-L1 expression in the Merkel cell carcinoma microenvironment: association with inflammation, Merkel cell polyomavirus and overall survival. Cancer Immunol Res (2013) 2.30

PD-1 expression on human CD8 T cells depends on both state of differentiation and activation status. AIDS (2007) 1.88

Cutaneous angiosarcoma of the head and neck. Cancer (1979) 1.20

Prognosis of lymph node metastasis in soft tissue sarcoma. Ann Surg Oncol (2004) 1.19

PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction. Clin Cancer Res (2013) 1.17

Increase of programmed death-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Mod Pathol (2010) 1.12

Increased programmed death-1+ tumor-infiltrating lymphocytes in classical Hodgkin lymphoma substantiate reduced overall survival. Hum Pathol (2009) 1.11

Cutaneous angiosarcoma: a single-institution experience. Ann Surg Oncol (2013) 1.09

Clinicopathological and prognostic value of programmed death ligand-1 (PD-L1) in renal cell carcinoma: a meta-analysis. Int J Clin Exp Med (2015) 1.04

Establishment of a human hemangiosarcoma cell line (ISO-HAS). Int J Cancer (1999) 1.03

Dual Faces of IFNγ in Cancer Progression: A Role of PD-L1 Induction in the Determination of Pro- and Antitumor Immunity. Clin Cancer Res (2016) 0.98

Chemoradiotherapy with taxane is superior to conventional surgery and radiotherapy in the management of cutaneous angiosarcoma: a multicentre, retrospective study. Br J Dermatol (2014) 0.93

Establishment of a novel experimental model of human angiosarcoma and a VEGF-targeting therapeutic experiment. J Dermatol Sci (2013) 0.84

Establishment of a new murine-phenotypic angiosarcoma cell line (ISOS-1). J Dermatol Sci (1998) 0.82

CD8⁺ tumor-infiltrating lymphocytes at primary sites as a possible prognostic factor of cutaneous angiosarcoma. Int J Cancer (2013) 0.82

Postirradiation primary vaginal angiosarcoma with widespread intra-abdominal metastasis. Int J Gynecol Pathol (2011) 0.78

Cutaneous angiosarcoma: own experience over 13 years. Clinical features, disease course and immunohistochemical profile. J Eur Acad Dermatol Venereol (2010) 0.77

Cutaneous angiosarcoma of the head and face: a single-center analysis of treatment outcomes in 43 patients in Japan. J Cancer Res Clin Oncol (2016) 0.77