Published in Endocrinology on January 01, 1997
Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist. J Med Chem (2004) 1.74
Differential regulation of the human adrenocorticotropin receptor [melanocortin-2 receptor (MC2R)] by human MC2R accessory protein isoforms alpha and beta in isogenic human embryonic kidney 293 cells. Mol Endocrinol (2007) 1.26
Characterization of blood pressure and morphological traits in cardiovascular-related organs in 13 different inbred mouse strains. J Appl Physiol (1985) (2004) 1.21
The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs. Mol Biol Evol (2003) 1.16
Angiotensin-II acute regulation of rapid response genes in human, bovine, and rat adrenocortical cells. J Mol Endocrinol (2007) 1.13
Adrenocortical dysregulation as a major player in insulin resistance and onset of obesity. Am J Physiol Endocrinol Metab (2007) 1.03
Proven infection-related sepsis induces a differential stress response early after ICU admission. Crit Care (2010) 1.03
Short pseudopeptides containing turn scaffolds with high AT2 receptor affinity. Bioorg Med Chem (2006) 0.95
Role of melanocortin receptor accessory proteins in the function of zebrafish melanocortin receptor type 2. Mol Cell Endocrinol (2010) 0.95
Role of asparagine-linked glycosylation in cell surface expression and function of the human adrenocorticotropin receptor (melanocortin 2 receptor) in 293/FRT cells. Endocrinology (2009) 0.95
Mother to infant or infant to mother? Reciprocal regulation of responsiveness to stress in rodents and the implications for humans. J Psychiatry Neurosci (2004) 0.94
Decreased expression of cyclic adenosine monophosphate-regulated aldose reductase (AKR1B1) is associated with malignancy in human sporadic adrenocortical tumors. J Clin Endocrinol Metab (2004) 0.94
Role of MAPKs in angiotensin II-induced steroidogenesis in rat glomerulosa cells. Mol Cell Endocrinol (2007) 0.91
Low-affinity neurotensin receptor (NTS2) signaling: internalization-dependent activation of extracellular signal-regulated kinases 1/2. Mol Pharmacol (2004) 0.90
Expression of extracellular matrix proteins and integrins in rat adrenal gland: importance for ACTH-associated functions. J Endocrinol (2007) 0.89
Nitric oxide and cyclic GMP are involved in angiotensin II AT(2) receptor effects on neurite outgrowth in NG108-15 cells. Neuroendocrinology (2002) 0.87
Role of tyrosine kinase receptors in angiotensin II AT2 receptor signaling: involvement in neurite outgrowth and in p42/p44mapk activation in NG108-15 cells. Endocrinology (2006) 0.86
Human melanocortin receptor 2 expression and functionality: effects of protein kinase A and protein kinase C on desensitization and internalization. Endocrinology (2006) 0.86
Hormone-sensitive lipase deficiency in mice causes lipid storage in the adrenal cortex and impaired corticosterone response to corticotropin stimulation. Endocrinology (2002) 0.86
Pharmacology and functional properties of NTS2 neurotensin receptors in cerebellar granule cells. J Biol Chem (2002) 0.86
The melanocortin receptor subtypes in chicken have high preference to ACTH-derived peptides. Br J Pharmacol (2004) 0.86
PAC1 receptor activation by PACAP-38 mediates Ca2+ release from a cAMP-dependent pool in human fetal adrenal gland chromaffin cells. J Biol Chem (2002) 0.86
Mechanisms of melanocortin-2 receptor (MC2R) internalization and recycling in human embryonic kidney (hek) cells: identification of Key Ser/Thr (S/T) amino acids. Mol Endocrinol (2011) 0.85
How does angiotensin AT(2) receptor activation help neuronal differentiation and improve neuronal pathological situations? Front Endocrinol (Lausanne) (2012) 0.85
The Angiotensin II Type 2 Receptor in Brain Functions: An Update. Int J Hypertens (2012) 0.85
Angiotensin II stimulates protein synthesis and inhibits proliferation in primary cultures of rat adrenal glomerulosa cells. Endocrinology (2004) 0.84
Bioinactive ACTH causing glucocorticoid deficiency. J Clin Endocrinol Metab (2013) 0.84
Cyclic AMP-independent involvement of Rap1/B-Raf in the angiotensin II AT2 receptor signaling pathway in NG108-15 cells. J Biol Chem (2002) 0.84
Comparative functional properties of two structurally similar selective nonpeptide drug-like ligands for the angiotensin II type-2 (AT(2)) receptor. Effects on neurite outgrowth in NG108-15 cells. Eur J Pharmacol (2012) 0.84
Selective angiotensin II AT2 receptor agonists: arylbenzylimidazole structure-activity relationships. J Med Chem (2006) 0.84
Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships. Bioorg Med Chem (2008) 0.84
Connection between integrins and cell activation in rat adrenal glomerulosa cells: a role for Arg-Gly-Asp peptide in the activation of the p42/p44(mapk) pathway and intracellular calcium. Endocrinology (2003) 0.83
Angiotensin II type 2 receptor promotes adipocyte differentiation and restores adipocyte size in high-fat/high-fructose diet-induced insulin resistance in rats. Am J Physiol Endocrinol Metab (2012) 0.83
Inhibition of DHCR24/seladin-1 impairs cellular homeostasis in prostate cancer. Prostate (2010) 0.83
In adrenal glomerulosa cells, angiotensin II inhibits proliferation by interfering with fibronectin-integrin signaling. Endocrinology (2008) 0.83
Expression and role of the angiotensin II AT2 receptor in human prostate tissue: in search of a new therapeutic option for prostate cancer. Prostate (2013) 0.83
Localization and characterization of evolutionarily conserved chromogranin A-derived peptides in the rat and human pituitary and adrenal glands. Cell Tissue Res (2002) 0.83
Selective angiotensin II AT(2) receptor agonists devoid of the imidazole ring system. Bioorg Med Chem (2007) 0.82
Localization and characterization of pituitary adenylate cyclase-activating polypeptide receptors in the human cerebellum during development. J Comp Neurol (2006) 0.82
From the first selective non-peptide AT(2) receptor agonist to structurally related antagonists. J Med Chem (2012) 0.81
New selective AT2 receptor ligands encompassing a gamma-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists. J Med Chem (2005) 0.81
Music and biological stress dampening in mechanically-ventilated patients at the intensive care unit ward-a prospective interventional randomized crossover trial. J Crit Care (2013) 0.81
Differential involvement of cytoskeleton and rho-guanosine 5'-triphosphatases in growth-promoting effects of angiotensin II in rat adrenal glomerulosa cells. Endocrinology (2006) 0.80
Angiotensin II type 2 receptor stimulation increases the rate of NG108-15 cell migration via actin depolymerization. Endocrinology (2008) 0.80
Inhibition of steroidogenic response to adrenocorticotropin by leptin: implications for the adrenal response to maternal separation in neonatal rats. Endocrinology (2003) 0.79
Involvement of protein kinase C alpha (PKC alpha) in the early action of angiotensin II type 2 (AT2) effects on neurite outgrowth in NG108-15 cells: AT2-receptor inhibits PKC alpha and p21ras activity. Endocrinology (2006) 0.79
Seladin-1 expression in rat adrenal gland: effect of adrenocorticotropic hormone treatment. J Endocrinol (2007) 0.78
Direct inhibitory effects of leptin on the neonatal adrenal and potential consequences for brain glucocorticoid feedback. Endocr Res (2004) 0.78
Extracellular matrix and hormones modulate DAX-1 localization in the human fetal adrenal gland. J Clin Endocrinol Metab (2005) 0.78
Fibronectin, laminin, and collagen IV as modulators of cell behavior during adrenal gland development in the human fetus. J Clin Endocrinol Metab (2002) 0.78
Angiotensin II pseudopeptides containing 1,3,5-trisubstituted benzene scaffolds with high AT2 receptor affinity. J Med Chem (2005) 0.78
Molecular characterization and functional regulation of melanocortin 2 receptor (MC2R) in the sea bass. A putative role in the adaptation to stress. PLoS One (2013) 0.78
Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition. Bioorg Med Chem (2010) 0.77
The C-terminal domains of melanocortin-2 receptor (MC2R) accessory proteins (MRAP1) influence their localization and ACTH-induced cAMP production. Gen Comp Endocrinol (2012) 0.77
From integrative signalling to metabolic disorders. J Steroid Biochem Mol Biol (2008) 0.77
The growth-promoting effects of angiotensin II in adrenal glomerulosa cells: an interactive tale. Mol Cell Endocrinol (2007) 0.76
Adrenocorticotropin hormone (ACTH) effects on MAPK phosphorylation in human fasciculata cells and in embryonic kidney 293 cells expressing human melanocortin 2 receptor (MC2R) and MC2R accessory protein (MRAP)β. Mol Cell Endocrinol (2010) 0.76
24-dehydrocholesterol reductase/seladin-1: a key protein differentially involved in adrenocorticotropin effects observed in human and rat adrenal cortex. Endocrinology (2009) 0.76
Ontogeny of PACAP receptors in the human cerebellum: perspectives of therapeutic applications. Regul Pept (2006) 0.76
Presence of task-1 channel in the laryngeal mucosa in the newborn lamb. Exp Lung Res (2011) 0.76
A Ras-Dependent Chloride Current Activated by Adrenocorticotropin in Rat Adrenal Zona Glomerulosa Cells1. Endocrinology (2000) 0.75
Role of extracellular matrix components in adult rat adrenal gland homeostasis. Endocr Res (2004) 0.75
Comparative Involvement of Cyclic Nucleotide Phosphodiesterases and Adenylyl Cyclase on Adrenocorticotropin-Induced Increase of Cyclic Adenosine Monophosphate in Rat and Human Glomerulosa Cells. Endocrinology (1999) 0.75
An oxidized metabolite of linoleic acid increases intracellular calcium in rat adrenal glomerulosa cells. Am J Physiol Endocrinol Metab (2006) 0.75
Angiotensin II type 2 receptor stimulation improves fatty acid ovarian uptake and hyperandrogenemia in an obese rat model of polycystic ovary syndrome. Endocrinology (2014) 0.75
Angiotensin II inhibits cell proliferation and stimulates protein synthesis in rat glomerulosa cells. Endocr Res (2004) 0.75
Differential responses to salt supplementation in adult male and female rat adrenal glands following intrauterine growth restriction. J Endocrinol (2011) 0.75