miR-134: A Human Cancer Suppressor?

PubWeight™: 0.77‹?›

🔗 View Article (PMID 28325280)

Published in Mol Ther Nucleic Acids on December 10, 2016

Authors

Jing-Yu Pan1, Feng Zhang1, Cheng-Cao Sun2, Shu-Jun Li3, Guang Li4, Feng-Yun Gong5, Tao Bo5, Jing He6, Rui-Xi Hua7, Wei-Dong Hu8, Zhan-Peng Yuan9, Xin Wang10, Qi-Qiang He1, De-Jia Li11

Author Affiliations

1: Department of Occupational and Environmental Health, School of Public Health, Wuhan University, 430071 Wuhan, Hubei, P. R. China.
2: Department of Occupational and Environmental Health, School of Public Health, Wuhan University, 430071 Wuhan, Hubei, P. R. China. Electronic address: chengcaosun@whu.edu.cn.
3: Department of Occupational and Environmental Health, School of Public Health, Wuhan University, 430071 Wuhan, Hubei, P. R. China; Wuhan Hospital for the Prevention and Treatment of Occupational Diseases, 430015 Wuhan, Hubei, P. R. China.
4: Department of Oncology, Wuhan Pu-Ai Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430034 Wuhan, Hubei, P. R. China.
5: Department of Infectious Diseases, Wuhan Medical Treatment Center, 430023 Wuhan, Hubei, P. R. China.
6: Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, 510623 Guangzhou, Guangdong, P. R. China.
7: Department of Oncology, The First Affiliated Hospital of Sun Yat-sen University, 510080 Guangzhou, Guangdong, P. R. China.
8: Department of Oncology, ZhongNan Hospital of Wuhan University, 430071 Wuhan, Hubei, P. R. China.
9: Department of Toxicology, School of Public Health, Wuhan University, 430071 Wuhan, P. R. China.
10: Department of Social Science and Public Health, School of Basic Medical Science, Jiujiang University, Jiujiang 332000, China.
11: Department of Occupational and Environmental Health, School of Public Health, Wuhan University, 430071 Wuhan, Hubei, P. R. China. Electronic address: lodjlwhu@sina.com.

Articles cited by this

(truncated to the top 100)

MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59

MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17

Cancer statistics, 2015. CA Cancer J Clin (2015) 57.51

MicroRNA signatures in human cancers. Nat Rev Cancer (2006) 46.29

Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer (2002) 34.99

Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A (2008) 33.65

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell (1993) 33.20

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature (2007) 21.53

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res (2008) 20.59

Cancer statistics in China, 2015. CA Cancer J Clin (2016) 12.92

Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem (2010) 12.06

microRNA target predictions in animals. Nat Genet (2006) 10.76

A brain-specific microRNA regulates dendritic spine development. Nature (2006) 10.18

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science (1992) 8.84

BCL-2 family: regulators of cell death. Annu Rev Immunol (1998) 6.41

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J Cell Biol (1999) 6.24

A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. Genome Res (2004) 5.77

Mature miR-184 as Potential Oncogenic microRNA of Squamous Cell Carcinoma of Tongue. Clin Cancer Res (2008) 5.46

Inhibition of cyclin-dependent kinases by p21. Mol Biol Cell (1995) 4.48

Cyclin-dependent kinase pathways as targets for cancer treatment. J Clin Oncol (2006) 4.20

A unified model of mammalian BCL-2 protein family interactions at the mitochondria. Mol Cell (2011) 3.72

Insulin analogues display IGF-I-like mitogenic and anti-apoptotic activities in cultured cancer cells. Diabetes Metab Res Rev (2009) 3.37

MicroRNA array analysis finds elevated serum miR-1290 accurately distinguishes patients with low-stage pancreatic cancer from healthy and disease controls. Clin Cancer Res (2013) 2.71

MicroRNA expression and identification of putative miRNA targets in ovarian cancer. PLoS One (2008) 2.60

Caspases and caspase inhibitors. Trends Biochem Sci (1997) 2.17

Epithelial to mesenchymal transition derived from repeated exposure to gefitinib determines the sensitivity to EGFR inhibitors in A549, a non-small cell lung cancer cell line. Lung Cancer (2008) 2.10

Microenvironmental regulation of epithelial-mesenchymal transitions in cancer. Cancer Res (2012) 2.00

Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene. Clin Cancer Res (2000) 1.91

Mir-34: a new weapon against cancer? Mol Ther Nucleic Acids (2014) 1.81

Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis. J Exp Med (1998) 1.74

Unambiguous identification of miRNA:target site interactions by different types of ligation reactions. Mol Cell (2014) 1.51

The secrets of the Bcl-2 family. Cell Death Differ (2012) 1.48

EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation. J Cell Sci (2007) 1.40

miR-10b promotes cell invasion through RhoC-AKT signaling pathway by targeting HOXD10 in gastric cancer. Int J Oncol (2012) 1.40

DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival. J Biol Chem (2011) 1.40

Gene expression profiling of drug-resistant small cell lung cancer cells by combining microRNA and cDNA expression analysis. Eur J Cancer (2010) 1.40

Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha in the pathogenesis of human cancer. J Pathol (2006) 1.38

MiR-134/487b/655 cluster regulates TGF-β-induced epithelial-mesenchymal transition and drug resistance to gefitinib by targeting MAGI2 in lung adenocarcinoma cells. Mol Cancer Ther (2013) 1.38

Localization- and mutation-dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co-expressed miRNAs located at 14q32.31. J Pathol (2010) 1.36

Upregulation of microRNA-451 increases cisplatin sensitivity of non-small cell lung cancer cell line (A549). J Exp Clin Cancer Res (2011) 1.33

Therapeutic strategies utilized in the setting of acquired resistance to EGFR tyrosine kinase inhibitors. Clin Cancer Res (2014) 1.33

miR-134 inhibits epithelial to mesenchymal transition by targeting FOXM1 in non-small cell lung cancer cells. FEBS Lett (2012) 1.32

An oncogenetic tree model in gastrointestinal stromal tumours (GISTs) identifies different pathways of cytogenetic evolution with prognostic implications. J Pathol (2007) 1.32

Apoptosis: targets in pancreatic cancer. Mol Cancer (2003) 1.31

High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth. Mol Oncol (2013) 1.30

Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage. Cancer Res (2003) 1.29

Effects of 1α,25 dihydroxyvitamin D3 and testosterone on miRNA and mRNA expression in LNCaP cells. Mol Cancer (2011) 1.20

Loss of has-miR-337-3p expression is associated with lymph node metastasis of human gastric cancer. J Exp Clin Cancer Res (2013) 1.19

Targeting of syndecan-1 by microRNA miR-10b promotes breast cancer cell motility and invasiveness via a Rho-GTPase- and E-cadherin-dependent mechanism. Int J Cancer (2012) 1.18

Down-regulation of c-Met and Bcl2 by microRNA-206, activates apoptosis, and inhibits tumor cell proliferation, migration and colony formation. Oncotarget (2015) 1.16

MicroRNA and target protein patterns reveal physiopathological features of glioma subtypes. PLoS One (2011) 1.15

Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors. Carcinogenesis (2013) 1.14

Hsa-miR-139-5p inhibits proliferation and causes apoptosis associated with down-regulation of c-Met. Oncotarget (2015) 1.13

MiRNA-10a is upregulated in NSCLC and may promote cancer by targeting PTEN. Oncotarget (2015) 1.06

N-cadherin-mediated cell-cell adhesion promotes cell migration in a three-dimensional matrix. J Cell Sci (2012) 1.06

miR-134 induces oncogenicity and metastasis in head and neck carcinoma through targeting WWOX gene. Int J Cancer (2013) 1.06

cDNA microarray analysis of invasive and tumorigenic phenotypes in a breast cancer model. Lab Invest (2004) 1.05

Diagnostic microRNA markers to screen for sporadic human colon cancer in stool: I. Proof of principle. Cancer Genomics Proteomics (2013) 1.05

Hepatocyte nuclear factor-4α reverses malignancy of hepatocellular carcinoma through regulating miR-134 in the DLK1-DIO3 region. Hepatology (2013) 1.02

Possible involvement of CCT5, RGS3, and YKT6 genes up-regulated in p53-mutated tumors in resistance to docetaxel in human breast cancers. Breast Cancer Res Treat (2006) 1.01

Genome-wide screening identified that miR-134 acts as a metastasis suppressor by targeting integrin β1 in hepatocellular carcinoma. PLoS One (2014) 1.01

MiR-134 functions as a regulator of cell proliferation, apoptosis, and migration involving lung septation. In Vitro Cell Dev Biol Anim (2012) 1.00

MicroRNA-423-5p Promotes Autophagy in Cancer Cells and Is Increased in Serum From Hepatocarcinoma Patients Treated With Sorafenib. Mol Ther Nucleic Acids (2015) 0.99

Circulating miRNA profile in HCV infected serum: novel insight into pathogenesis. Sci Rep (2013) 0.99

Hsa-miR-326 targets CCND1 and inhibits non-small cell lung cancer development. Oncotarget (2016) 0.98

Dihydropyrimidine dehydrogenase (DPD) expression is negatively regulated by certain microRNAs in human lung tissues. Lung Cancer (2012) 0.98

A MicroRNA precursor surveillance system in quality control of MicroRNA synthesis. Mol Cell (2014) 0.98

Exon sequencing and high resolution haplotype analysis of ABC transporter genes implicated in drug resistance. Pharmacogenet Genomics (2006) 0.97

MiR-134 regulates the proliferation and invasion of glioblastoma cells by reducing Nanog expression. Int J Oncol (2013) 0.96

Multiple receptor tyrosine kinases converge on microRNA-134 to control KRAS, STAT5B, and glioblastoma. Cell Death Differ (2014) 0.95

MicroRNA-187-3p mitigates non-small cell lung cancer (NSCLC) development through down-regulation of BCL6. Biochem Biophys Res Commun (2016) 0.93

MicroRNA-134 suppresses endometrial cancer stem cells by targeting POGLUT1 and Notch pathway proteins. FEBS Lett (2014) 0.92

MicroRNAs in the pathophysiology and treatment of status epilepticus. Front Mol Neurosci (2013) 0.91

Chrysin inhibits tumor promoter-induced MMP-9 expression by blocking AP-1 via suppression of ERK and JNK pathways in gastric cancer cells. PLoS One (2015) 0.91

Collective and individual migration following the epithelial-mesenchymal transition. Nat Mater (2014) 0.90

miR-134 functions as a tumor suppressor in cell proliferation and epithelial-to-mesenchymal Transition by targeting KRAS in renal cell carcinoma cells. DNA Cell Biol (2015) 0.90

A novel saliva-based microRNA biomarker panel to detect head and neck cancers. Cell Oncol (Dordr) (2014) 0.90

Hsa-miR-329 exerts tumor suppressor function through down-regulation of MET in non-small cell lung cancer. Oncotarget (2016) 0.89

Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal Cancer. Mol Ther Nucleic Acids (2015) 0.89

Hsa-miR-134 suppresses non-small cell lung cancer (NSCLC) development through down-regulation of CCND1. Oncotarget (2016) 0.88

Circulating MiR-19b-3p, MiR-134-5p and MiR-186-5p are Promising Novel Biomarkers for Early Diagnosis of Acute Myocardial Infarction. Cell Physiol Biochem (2016) 0.87

Occupational cancer in Britain. Remaining cancer sites: brain, bone, soft tissue sarcoma and thyroid. Br J Cancer (2012) 0.87

MicroRNA-134 modulates resistance to doxorubicin in human breast cancer cells by downregulating ABCC1. Biotechnol Lett (2015) 0.85

Diagnostic Value of Circulating Extracellular miR-134, miR-185, and miR-22 Levels in Lung Adenocarcinoma-Associated Malignant Pleural Effusion. Cancer Res Treat (2014) 0.84

MicroRNAs are part of the regulatory network that controls EGF induced apoptosis, including elements of the JAK/STAT pathway, in A431 cells. PLoS One (2015) 0.84

MicroRNA-134 regulates lung cancer cell H69 growth and apoptosis by targeting WWOX gene and suppressing the ERK1/2 signaling pathway. Biochem Biophys Res Commun (2015) 0.83

Dysregulated Serum MicroRNA Expression Profile and Potential Biomarkers in Hepatitis C Virus-infected Patients. Int J Med Sci (2015) 0.83

A radiosensitivity MiRNA signature validated by the TCGA database for head and neck squamous cell carcinomas. Oncotarget (2015) 0.83

Overexpression of hCLP46 enhances Notch activation and regulates cell proliferation in a cell type-dependent manner. Cell Prolif (2013) 0.82

MiR-197 induces Taxol resistance in human ovarian cancer cells by regulating NLK. Tumour Biol (2015) 0.82

MiR-134-dependent regulation of Pumilio-2 is necessary for homeostatic synaptic depression. EMBO J (2014) 0.81

Hyaluronic acid promotes the expression of progesterone receptor membrane component 1 via epigenetic silencing of miR-139-5p in human and rat granulosa cells. Biol Reprod (2014) 0.81

YKT6 expression, exosome release, and survival in non-small cell lung cancer. Oncotarget (2016) 0.80

Advances in the diagnosis of pleural disease in lung cancer. Ther Adv Respir Dis (2011) 0.79

Expression Profiles and Clinical Significance of MicroRNAs in Papillary Renal Cell Carcinoma: A STROBE-Compliant Observational Study. Medicine (Baltimore) (2015) 0.79

miRNA interventions serve as 'magic bullets' in the reversal of glioblastoma hallmarks. Oncotarget (2015) 0.79

Induction of Apoptosis in Human Leukemic Cell Lines by Diallyl Disulfide via Modulation of EGFR/ERK/PKM2 Signaling Pathways. Asian Pac J Cancer Prev (2015) 0.78

Genetic variation of the ABC transporter gene ABCC1 (Multidrug resistance protein 1 - MRP1) in the Polish population. BMC Genet (2015) 0.78

Chronic administration tetrahydroxystilbene glucoside promotes hippocampal memory and synaptic plasticity and activates ERKs, CaMKII and SIRT1/miR-134 in vivo. J Ethnopharmacol (2016) 0.77

Two lung development-related microRNAs, miR-134 and miR-187, are differentially expressed in lung tumors. Gene (2015) 0.77