Published in Mol Cell Biol on February 01, 1988
A purified mariner transposase is sufficient to mediate transposition in vitro. EMBO J (1996) 5.34
A new kind of informational suppression in the nematode Caenorhabditis elegans. Genetics (1989) 3.69
Target-selected gene inactivation in Caenorhabditis elegans by using a frozen transposon insertion mutant bank. Proc Natl Acad Sci U S A (1993) 3.43
Insertion and excision of the transposable element mariner in Drosophila. Genetics (1990) 2.56
The origin of footprints of the Tc1 transposon of Caenorhabditis elegans. EMBO J (1991) 2.32
Site-selected insertion of the transposon Tc1 into a Caenorhabditis elegans myosin light chain gene. Mol Cell Biol (1993) 1.92
The Tc3 family of transposable genetic elements in Caenorhabditis elegans. Genetics (1989) 1.66
Mobile Minos elements from Drosophila hydei encode a two-exon transposase with similarity to the paired DNA-binding domain. Proc Natl Acad Sci U S A (1994) 1.65
Structure-based prediction of insertion-site preferences of transposons into chromosomes. Nucleic Acids Res (2006) 1.48
The transposable element Uhu from Hawaiian Drosophila--member of the widely dispersed class of Tc1-like transposons. Nucleic Acids Res (1990) 1.30
Target site choice of the related transposable elements Tc1 and Tc3 of Caenorhabditis elegans. Nucleic Acids Res (1994) 1.26
The Caenorhabditis elegans unc-93 gene encodes a putative transmembrane protein that regulates muscle contraction. J Cell Biol (1992) 1.24
Tc4, a Caenorhabditis elegans transposable element with an unusual fold-back structure. Proc Natl Acad Sci U S A (1991) 1.19
Splicing removes the Caenorhabditis elegans transposon Tc1 from most mutant pre-mRNAs. Mol Cell Biol (1996) 1.18
Mobilization of a Minos transposon in Drosophila melanogaster chromosomes and chromatid repair by heteroduplex formation. Genetics (1997) 1.06
Gene conversion and end-joining-repair double-strand breaks in the Caenorhabditis elegans germline. Genetics (2008) 1.03
Target choice determinants of the Tc1 transposon of Caenorhabditis elegans. Nucleic Acids Res (1997) 1.02
Germline excision of the transposable element Tc1 in C. elegans. Nucleic Acids Res (1991) 1.02
Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy. Transl Res (2013) 1.01
Tc8, a Tourist-like transposon in Caenorhabditis elegans. Genetics (2001) 0.93
Extrachromosomal circular copies of the transposon Tc1. Nucleic Acids Res (1993) 0.89
Transposition of cyanobacterium insertion element ISY100 in Escherichia coli. J Bacteriol (2002) 0.83
Manipulating the Caenorhabditis elegans genome using mariner transposons. Genetica (2009) 0.81
Bioinformatic inference of specific and general transcription factor binding sites in the plant pathogen Phytophthora infestans. PLoS One (2012) 0.81
Quantitative variation of LINE-1 sequences in five species and three subspecies of the subgenus Mus and in five Robertsonian races of Mus musculus domesticus. Chromosome Res (2009) 0.77
Transposition of the autonomous Fot1 element in the filamentous fungus Fusarium oxysporum. Genetics (1999) 0.76
Imprecise excision of the Caenorhabditis elegans transposon Tc1 creates functional 5' splice sites. Mol Cell Biol (1994) 0.76
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
The genetics of Caenorhabditis elegans. Genetics (1974) 102.14
New M13 vectors for cloning. Methods Enzymol (1983) 90.74
The DNA of Caenorhabditis elegans. Genetics (1974) 37.68
Lambda replacement vectors carrying polylinker sequences. J Mol Biol (1983) 32.76
Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev Biol (1977) 19.51
Splicing of messenger RNA precursors. Annu Rev Biochem (1986) 14.41
Structures of P transposable elements and their sites of insertion and excision in the Drosophila melanogaster genome. Cell (1983) 13.18
Molecular identification and isolation of the Waxy locus in maize. Cell (1983) 9.07
The molecular basis of P-M hybrid dysgenesis: the role of the P element, a P-strain-specific transposon family. Cell (1982) 8.95
Molecular Genetics of the Bithorax Complex in Drosophila melanogaster. Science (1983) 7.94
Tissue specificity of Drosophila P element transposition is regulated at the level of mRNA splicing. Cell (1986) 7.45
DNA rearrangements associated with a transposable element in yeast. Cell (1980) 7.03
The P family of transposable elements in Drosophila. Annu Rev Genet (1983) 6.56
A role for exon sequences and splice-site proximity in splice-site selection. Cell (1986) 6.41
A simple method to recover intact high molecular weight RNA and DNA after electrophoretic separation in low gelling temperature agarose gels. Anal Biochem (1979) 5.98
A mutant affecting the heavy chain of myosin in Caenorhabditis elegans. J Mol Biol (1974) 5.33
Mating signals control expression of mutations resulting from insertion of a transposable repetitive element adjacent to diverse yeast genes. Cell (1980) 5.20
Insertion of DNA activates the cryptic bgl operon in E. coli K12. Nature (1981) 4.59
A symmetrical six-base-pair target site sequence determines Tn10 insertion specificity. Cell (1982) 4.36
Sequence of the C. elegans transposable element Tc1. Nucleic Acids Res (1983) 4.32
DNA sequence at the integration sites of the insertion element IS1. Cell (1978) 4.27
Molecular analysis of ds controlling element mutations at the adh1 locus of maize. Science (1984) 3.93
Protein structural domains in the Caenorhabditis elegans unc-54 myosin heavy chain gene are not separated by introns. Proc Natl Acad Sci U S A (1983) 3.77
Transposable elements generate novel spatial patterns of gene expression in Antirrhinum majus. Cell (1986) 3.77
Excision of the DBA ecotropic provirus in dilute coat-color revertants of mice occurs by homologous recombination involving the viral LTRs. Cell (1983) 3.66
Evidence for a transposon in Caenorhabditis elegans. Cell (1983) 3.65
IS1 insertion generates duplication of a nine base pair sequence at its target site. Cell (1978) 3.55
Circles with two tandem LTRs are precursors to integrated retrovirus DNA. Cell (1984) 3.45
High-frequency excision of transposable element Tc 1 in the nematode Caenorhabditis elegans is limited to somatic cells. Cell (1984) 3.23
A trans-acting product needed for P factor transposition in Drosophila. Science (1984) 3.21
A transposable element inserted just 5' to a Drosophila glue protein gene alters gene expression and chromatin structure. Cell (1983) 3.13
Analysis of a transposable element in Caenorhabditis elegans. Proc Natl Acad Sci U S A (1983) 3.12
The 17-kb Tam1 element of Antirrhinum majus induces a 3-bp duplication upon integration into the chalcone synthase gene. EMBO J (1984) 3.07
Specificity of transposon Tn5 insertion. Genetics (1983) 3.04
Activation of a transposable element in the germ line but not the soma of Caenorhabditis elegans. Nature (1987) 3.00
Unique insertion site of Tn7 in the E. coli chromosome. Nature (1982) 2.65
Molecular cloning of the muscle gene unc-22 in Caenorhabditis elegans by Tc1 transposon tagging. Proc Natl Acad Sci U S A (1986) 2.56
Hybrid dysgenesis-induced revertants of insertions at the 5' end of the rudimentary gene in Drosophila melanogaster: transposon-induced control mutations. Genetics (1986) 2.51
Insertion of a movable genetic element, 297, into the T-A-T-A box for the H3 histone gene in Drosophila melanogaster. Proc Natl Acad Sci U S A (1982) 2.49
Long terminal repeat nucleotide sequence and specific insertion of the gypsy transposon. Proc Natl Acad Sci U S A (1984) 2.34
Transposition of Tc1 in the nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A (1985) 2.33
Controlling element-induced alterations in UDPglucose:flavonoid glucosyltransferase, the enzyme specified by the bronze locus in maize. Proc Natl Acad Sci U S A (1977) 2.31
Spontaneous unstable unc-22 IV mutations in C. elegans var. Bergerac. Genetics (1984) 2.24
Genetic evidence that Tn10 transposes by a nonreplicative mechanism. Cell (1986) 2.05
Extrachromosomal copies of transposon Tc1 in the nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A (1984) 1.91
New bacteriophage lambda vectors with positive selection for cloned inserts. Methods Enzymol (1983) 1.85
Target sequences for the C. elegans transposable element Tc1. Nucleic Acids Res (1983) 1.84
Mutations in the unc-54 myosin heavy chain gene of Caenorhabditis elegans that alter contractility but not muscle structure. Cell (1982) 1.83
The gene structures of spontaneous mutations affecting a Caenorhabditis elegans myosin heavy chain gene. Genetics (1985) 1.79
Sites of P element insertion and structures of P element deletions in the 5' region of Drosophila melanogaster RpII215. Mol Cell Biol (1986) 1.77
RNA splice site selection: evidence for a 5' leads to 3' scanning model. Science (1983) 1.76
Transposase promotes double strand breaks and single strand joints at Tn10 termini in vivo. Cell (1984) 1.68
The evolutionary implications of mobile genetic elements. Annu Rev Genet (1984) 1.58
Sequence-specific insertion of the Drosophila transposable genetic element 17.6. Nature (1984) 1.51
Integration site preferences of the Alu family and similar repetitive DNA sequences. Nucleic Acids Res (1985) 1.50
Specificity of insertion of IS1. J Mol Biol (1985) 1.41
Isolation of the closed circular form of the transposable element Tc1 in Caenorhabditis elegans. Nature (1984) 1.40
Excision of copia element in a revertant of the white-apricot mutation of Drosophila melanogaster leaves behind one long-terminal repeat. Mol Gen Genet (1985) 1.39
Immunocytochemical localization of two myosins within the same muslce cells in Caenorhabditis elegans. Cell (1978) 1.37
Nearly precise excision: a new type of DNA alteration associated with the translocatable element Tn10. Cell (1979) 1.20
C. elegans unc-105 mutations affect muscle and are suppressed by other mutations that affect muscle. Genetics (1986) 1.11
Tc1(Hin): a form of the transposable element Tc1 in Caenorhabditis elegans. Can J Biochem Cell Biol (1985) 1.03
Evidence in a nematode for regulation of transposon excision by tissue-specific factors. Mol Gen Genet (1986) 0.95
RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules. J Cell Biol (1999) 8.07
Human serum activities against Hemophilus influenzae, type b. J Clin Invest (1972) 7.85
Stress granules: sites of mRNA triage that regulate mRNA stability and translatability. Biochem Soc Trans (2002) 6.08
Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules. J Cell Biol (2000) 5.99
mRNA surveillance by the Caenorhabditis elegans smg genes. Genes Dev (1993) 5.94
A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells. Cell (1991) 5.65
Spontaneous tandem genetic duplications in Salmonella typhimurium arise by unequal recombination between rRNA (rrn) cistrons. Proc Natl Acad Sci U S A (1981) 4.85
Effect of systemic glucocorticoids on exacerbations of chronic obstructive pulmonary disease. Department of Veterans Affairs Cooperative Study Group. N Engl J Med (1999) 4.66
TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha. EMBO J (2000) 4.41
Standardization of an opsonophagocytic assay for the measurement of functional antibody activity against Streptococcus pneumoniae using differentiated HL-60 cells. Clin Diagn Lab Immunol (1997) 4.28
Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis. Gut (2009) 4.06
Smoking cessation in patients with chronic obstructive pulmonary disease: a double-blind, placebo-controlled, randomised trial. Lancet (2001) 3.96
Defining substance use disorders: do we really need more than heavy use? Alcohol Alcohol (2013) 3.72
A new kind of informational suppression in the nematode Caenorhabditis elegans. Genetics (1989) 3.69
Responses of children immunized with the capsular polysaccharide of Hemophilus influenzae, type b. Pediatrics (1973) 3.33
SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast. Mol Cell Biol (1999) 3.18
General practitioners and alternative medicine. J R Coll Gen Pract (1987) 3.10
Life and death in the cytoplasm: messages from the 3' end. Curr Opin Genet Dev (1997) 3.01
Activation of a transposable element in the germ line but not the soma of Caenorhabditis elegans. Nature (1987) 3.00
The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing. Mol Cell (2000) 2.97
Individual RNA recognition motifs of TIA-1 and TIAR have different RNA binding specificities. J Biol Chem (1996) 2.89
Electron microscope observations on compounds 48-80-induced degranulation in rat mast cells. Evidence for sequential exocytosis of storage granules. J Cell Biol (1971) 2.88
Immunization of humans with polyribophosphate, the capsular antigen of Hemophilus influenzae, type b. J Clin Invest (1972) 2.81
Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells. Blood (1996) 2.62
Increased rate of tuberculin skin test conversion among workers at a university hospital. Infect Control Hosp Epidemiol (1992) 2.60
Inhibition of protein synthesis by spectinomycin. Science (1965) 2.54
What are safe levels of alcohol consumption? Br Med J (Clin Res Ed) (1984) 2.54
Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans. Genes Dev (2000) 2.52
Circulating polyribophosphate in Hemophilus influenzae, type b meningitis. Correlation with clinical course and antibody response. J Clin Invest (1975) 2.48
Phenotypic and genetic variation in the susceptibility of Haemophilus influenzae type b to antibodies to somatic antigens. J Clin Invest (1980) 2.42
Identification and functional characterization of a TIA-1-related nucleolysin. Proc Natl Acad Sci U S A (1992) 2.38
Countercurrent immunoelectrophoresis in the diagnosis of systemic diseases caused by Hemophilus infleunzae type b. J Pediatr (1972) 2.33
Transposition of Tc1 in the nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A (1985) 2.33
Interleukin-6 response to deliberate colonization of the human urinary tract with gram-negative bacteria. Infect Immun (1991) 2.22
Intranasal immunization with killed unencapsulated whole cells prevents colonization and invasive disease by capsulated pneumococci. Infect Immun (2001) 2.19
The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell death. Proc Natl Acad Sci U S A (1995) 2.15
Development of executive functions through late childhood and adolescence in an Australian sample. Dev Neuropsychol (2001) 2.14
A selection for myosin heavy chain mutants in the nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A (1984) 2.10
Safe limits of drinking: general practitioners' views. Br Med J (Clin Res Ed) (1985) 2.06
The role of encapsulation and host age in the clearance of Haemophilus influenzae bacteremia. J Infect Dis (1977) 2.01
Supercoiling in closed circular DNA: dependence upon ion type and concentration. Biochemistry (1978) 2.01
Antibody responses to Haemophilus influenzae type b and diphtheria toxin induced by conjugates of oligosaccharides of the type b capsule with the nontoxic protein CRM197. Infect Immun (1983) 1.99
Cell proteins TIA-1 and TIAR interact with the 3' stem-loop of the West Nile virus complementary minus-strand RNA and facilitate virus replication. J Virol (2002) 1.98
Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma. Cancer Res (1993) 1.95
Community general practitioner. Lancet (1985) 1.94
The paradox of Hemophilus infuenzae type B bacteremia in the presence of serum bactericidal activity. J Clin Invest (1976) 1.94
Effect of spectinomycin on polypeptide synthesis in extracts of Escherichia coli. J Mol Biol (1967) 1.93
Site-selected insertion of the transposon Tc1 into a Caenorhabditis elegans myosin light chain gene. Mol Cell Biol (1993) 1.92
smg-7 is required for mRNA surveillance in Caenorhabditis elegans. Genetics (1999) 1.90
Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: a randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients. Crit Care Med (2001) 1.88
G proteins are required for spatial orientation of early cell cleavages in C. elegans embryos. Cell (1996) 1.86
The AAPPQ revisited: the measurement of general practitioners' attitudes to alcohol problems. Br J Addict (1987) 1.85
The gene structures of spontaneous mutations affecting a Caenorhabditis elegans myosin heavy chain gene. Genetics (1985) 1.79
Intrinsic tritium labeling of the capsular polysaccharide antigen of Haemophilus influenzae type B. J Immunol (1978) 1.79
RNA-binding protein TIAR is essential for primordial germ cell development. Proc Natl Acad Sci U S A (1998) 1.76
Death, autoantigen modifications, and tolerance. Arthritis Res (2000) 1.75
Malignant pleural effusion of multiple myeloma: prognostic factors and outcome. Leuk Lymphoma (2005) 1.75
Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis. J Exp Med (1995) 1.75
Advances in the molecular genetic analysis of the flax-flax rust interaction. Annu Rev Phytopathol (1997) 1.72
BOLD based functional MRI at 4 Tesla includes a capillary bed contribution: echo-planar imaging correlates with previous optical imaging using intrinsic signals. Magn Reson Med (1995) 1.71
Interlaboratory study evaluating quantitation of antibodies to Haemophilus influenzae type b polysaccharide by enzyme-linked immunosorbent assay. Clin Diagn Lab Immunol (1996) 1.71
Sequential exocytosis of storage granules during antigen-induced histamine release from sensitized rat mast cells in vitro. An electron microscopic study. Acta Physiol Scand (1973) 1.70
Learning by internal medicine residents: differences and similarities of perceptions by residents and faculty. J Gen Intern Med (1995) 1.69
Managing alcohol problems in general practice. Br Med J (Clin Res Ed) (1985) 1.69
Trichothecene mycotoxins trigger a ribotoxic stress response that activates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase and induces apoptosis. J Biol Chem (1999) 1.69
Twelve year outcomes following bacterial meningitis: further evidence for persisting effects. Arch Dis Child (2000) 1.67
The Tc3 family of transposable genetic elements in Caenorhabditis elegans. Genetics (1989) 1.66
Proteins phosphorylated during stress-induced apoptosis are common targets for autoantibody production in patients with systemic lupus erythematosus. J Exp Med (1997) 1.66
Role of immunity in the clearance of bacteremia due to Haemophilus influenzae. J Infect Dis (1978) 1.65
Human interferon-gamma is internalized and degraded by cultured fibroblasts. J Biol Chem (1983) 1.63
Structures of spontaneous deletions in Caenorhabditis elegans. Mol Cell Biol (1988) 1.61
Characterization of human antibody to polyribophosphate, the capsular antigen of Hemophilus influenzae, type B. Clin Immunol Immunopathol (1973) 1.60
Functions of the myosin ATP and actin binding sites are required for C. elegans thick filament assembly. Cell (1990) 1.59
Phosphatidate and oxidized fatty acids are calcium ionophores. Studies employing arsenazo III in liposomes. J Biol Chem (1981) 1.59
mRNA surveillance mitigates genetic dominance in Caenorhabditis elegans. Mol Gen Genet (1998) 1.58
Randomized controlled trial of general practitioner intervention in women with excessive alcohol consumption. Drug Alcohol Rev (1991) 1.57
A novel role for interleukin-18 in human natural killer cell death: high serum levels and low natural killer cell numbers in patients with systemic autoimmune diseases. Arthritis Rheum (2001) 1.57
Structure, tissue distribution and genomic organization of the murine RRM-type RNA binding proteins TIA-1 and TIAR. Nucleic Acids Res (1996) 1.56
Specific binding of 125I-human interferon-gamma to high affinity receptors on human fibroblasts. J Biol Chem (1982) 1.54
Haemophilus influenzae disease in Alaskan Eskimos: characteristics of a population with an unusual incidence of invasive disease. Lancet (1981) 1.53
Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell-and natural killer cell-mediated cytotoxicity. Eur J Immunol (1996) 1.51
WHO Europe evidence based recommendations on the treatment of tobacco dependence. Tob Control (2002) 1.51
Isoelectric focusing of human antibody to the Haemophilus influenzae b capsular polysaccharide: restricted and identical spectrotypes in adults. J Immunol (1985) 1.48
Structural similarity between Fc receptors and T cell receptors. Expression of the gamma-subunit of Fc epsilon RI in human T cells, natural killer cells and thymocytes. J Immunol (1991) 1.44
Is alcohol a carcinogenic risk? Br J Addict (1990) 1.43
Tyrosine phosphorylation of the Fc gamma RIII(CD16): zeta complex in human natural killer cells. Induction by antibody-dependent cytotoxicity but not by natural killing. J Immunol (1991) 1.43
Myosin heavy-chain mutations that disrupt Caenorhabditis elegans thick filament assembly. Genes Dev (1988) 1.43
Misonidazole-a drug for trial in radiotherapy and oncology. Int J Radiat Oncol Biol Phys (1979) 1.41
Isolation of the capsular polysaccharide from culture supernatant of Haemophilus influenzae type b. Infect Immun (1977) 1.40
Delivering educational programs via telephone: teleconferencing. Vet Hum Toxicol (1984) 1.40
The protective level of serum antibodies to the capsular polysaccharide of Haemophilus influenzae type b. J Infect Dis (1984) 1.40
Efficacy of metered-dose inhaler administration of albuterol in intubated infants. Chest (1997) 1.40
Interchangeability of conjugated Haemophilus influenzae type b vaccines in infants. JAMA (1995) 1.40
Second cancers after conservative surgery and radiation for stages I-II breast cancer: identifying a subset of women at increased risk. Int J Radiat Oncol Biol Phys (2001) 1.40
Posttranslational protein modifications, apoptosis, and the bypass of tolerance to autoantigens. Arthritis Rheum (1998) 1.39
Multiple carpo-metacarpal dislocations. J Hand Surg Br (1989) 1.39
The neurotoxicity of misonidazole and its relationship to dose, half-life and concentration in the serum. Br J Cancer Suppl (1978) 1.38
Mode of activation of hippocampal pyramidal cells by excitatory synapses on dendrites. Exp Brain Res (1966) 1.38
Management of large-scale disasters. S Afr Med J (1993) 1.38