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Rank Title Journal Year PubWeight™‹?›
1 Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods 1985 9.05
2 Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat. Pharmacol Biochem Behav 1986 2.73
3 Effects of moderate alcohol consumption on the central nervous system. Alcohol Clin Exp Res 1998 2.60
4 Can social interaction be used to measure anxiety? Br J Pharmacol 1978 2.50
5 Validity of head-dipping as a measure of exploration in a modified hole-board. Psychopharmacologia 1975 2.46
6 The use of social interaction as a method for detecting anxiolytic activity of chlordiazepoxide-like drugs. J Neurosci Methods 1980 2.26
7 Sex differences in animal tests of anxiety. Physiol Behav 1991 1.74
8 The influence of open arm ledges and maze experience in the elevated plus-maze. Pharmacol Biochem Behav 1996 1.39
9 Factor analysis shows that female rat behaviour is characterized primarily by activity, male rats are driven by sex and anxiety. Pharmacol Biochem Behav 1999 1.26
10 5-HT1A and benzodiazepine receptors in the basolateral amygdala modulate anxiety in the social interaction test, but not in the elevated plus-maze. Brain Res 1996 1.25
11 Do lorazeam-induced deficits in learning result from impaired rehearsal, reduced motivation or increased sedation? Br J Clin Pharmacol 1982 1.20
12 Nicotine self-administration and withdrawal: modulation of anxiety in the social interaction test in rats. Psychopharmacology (Berl) 2001 1.13
13 The reliability of the hole-board apparatus. Psychopharmacologia 1975 1.11
14 Corticotropin-releasing factor has an anxiogenic action in the social interaction test. Horm Behav 1987 1.11
15 Effects of ethanol and chlordiazepoxide on social interaction in rats [proceedings]. Br J Pharmacol 1976 1.10
16 Studies on the role of ACTH and of 5-HT in anxiety, using an animal model. J Pharm Pharmacol 1978 1.10
17 Evidence for a complex influence of nicotinic acetylcholine receptors on hippocampal serotonin release. J Neurochem 2000 1.08
18 Behavioral consequences in animal tests of anxiety and exploration of exposure to cat odor. Brain Res Bull 1992 1.07
19 Handling history of rats modifies behavioural effects of drugs in the elevated plus-maze test of anxiety. Eur J Pharmacol 1993 1.07
20 Impaired performance and sedation after a single dose of lorazepam. Psychopharmacology (Berl) 1979 1.03
21 Evidence that the median raphé nucleus--dorsal hippocampal pathway mediates diazepam withdrawal-induced anxiety. Psychopharmacology (Berl) 1997 1.03
22 Time-course of changes in the social interaction test of anxiety following acute and chronic administration of nicotine. Behav Pharmacol 1999 1.00
23 Tolerance to nicotine's effects in the elevated plus-maze and increased anxiety during withdrawal. Pharmacol Biochem Behav 2001 1.00
24 The dorsal raphé nucleus is a crucial structure mediating nicotine's anxiolytic effects and the development of tolerance and withdrawal responses. Psychopharmacology (Berl) 2001 0.99
25 Involvement of 5-HT1A receptors in behavioural effects of the cannabinoid receptor agonist CP 55,940 in male rats. Behav Pharmacol 2004 0.98
26 Intrinsic actions of the benzodiazepine receptor antagonist Ro 15-1788. Psychopharmacology (Berl) 1986 0.98
27 Antagonistic effects of caffeine and yohimbine in animal tests of anxiety. Eur J Pharmacol 1989 0.97
28 The effects of triazolobenzodiazepines in two animal tests of anxiety and in the holeboard. Br J Pharmacol 1985 0.97
29 Interaction between effects of caffeine and lorazepam in performance tests and self-ratings. J Clin Psychopharmacol 1982 0.97
30 Acute nicotine decreases, and chronic nicotine increases the expression of brain-derived neurotrophic factor mRNA in rat hippocampus. Brain Res Mol Brain Res 2000 0.95
31 Yohimbine's anxiogenic action: evidence for noradrenergic and dopaminergic sites. Pharmacol Biochem Behav 1989 0.95
32 Multiple sites of action for anxiogenic drugs: behavioural, electrophysiological and biochemical correlations. Psychopharmacology (Berl) 1984 0.95
33 Corticosterone -- an anxiogenic or an anxiolytic agent? J Pharm Pharmacol 1979 0.94
34 Modulation of behaviour on trials 1 and 2 in the elevated plus-maze test of anxiety after systemic and hippocampal administration of nicotine. Psychopharmacology (Berl) 1999 0.94
35 Stimulation of benzodiazepine receptors in the dorsal hippocampus and median raphé reveals differential GABAergic control in two animal tests of anxiety. Eur J Neurosci 1998 0.94
36 The anxiogenic action of benzodiazepine antagonists. Neuropharmacology 1982 0.94
37 Aversive and appetitive properties of anxiogenic and anxiolytic agents. Behav Brain Res 1986 0.93
38 Selectively bred lines of rats differ in social interaction and hippocampal 5-HT1A receptor function: a link between anxiety and depression? Pharmacol Biochem Behav 1998 0.93
39 Sedative effects of PK 9084 and PK 8165, alone and in combination with chlordiazepoxide. Br J Pharmacol 1983 0.93
40 Mice lacking the cell adhesion molecule Thy-1 fail to use socially transmitted cues to direct their choice of food. Curr Biol 2000 0.92
41 Do the reductions in social interaction produced by picrotoxin and pentylenetetrazole indicate anxiogenic actions? Neuropharmacology 1984 0.92
42 Methodological considerations in neurobehavioral teratology. Pharmacol Biochem Behav 1996 0.92
43 5-HT1A receptors in the median raphe nucleus and dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours respectively. Eur J Pharmacol 1994 0.91
44 Effects of two anxiolytics on distraction, habituation and dishabitiuation. Pharmacol Biochem Behav 1977 0.91
45 Decreased 5-HT1A and increased 5-HT2A receptor binding after chronic corticosterone associated with a behavioural indication of depression but not anxiety. Psychoneuroendocrinology 1997 0.91
46 Regional differences in rat benzodiazepine binding in response to novelty and cat odour. Neuropharmacology 1994 0.90
47 On the convulsant action of Ro 5-4864 and the existence of a micromolar benzodiazepine binding site in rat brain. Psychopharmacology (Berl) 1984 0.90
48 Selective agonists and antagonists for 5-hydroxytryptamine receptor subtypes, and interactions with yohimbine and FG 7142 using the elevated plus-maze test in the rat. J Pharm Pharmacol 1987 0.90
49 Pharmacokinetic studies on Ro 15-1788, a benzodiazepine receptor ligand, in the brain of the rat. Brain Res 1984 0.90
50 Tolerance to the anti-pentylenetetrazole effects of diazepam in the mouse. Psychopharmacology (Berl) 1983 0.90
51 The effects of piracetam on acquisition and retention of habituation [proceedings]. Br J Pharmacol 1977 0.90
52 The effect of treatment regimen on the development of tolerance to the sedative and anxiolytic effects of diazepam. Psychopharmacology (Berl) 1999 0.89
53 Antagonism of the anxiolytic effect of nicotine in the dorsal raphe nucleus by dihydro-beta-erythroidine. Pharmacol Biochem Behav 2001 0.89
54 A five minute experience in the elevated plus-maze alters the state of the benzodiazepine receptor in the dorsal raphe nucleus. J Neurosci 1997 0.89
55 A test of anxiety that distinguishes between the actions of benzodiazepines and those of other minor tranquilisers and of stimulants. Pharmacol Biochem Behav 1979 0.89
56 Nicotine regulates 5-HT(1A) receptor gene expression in the cerebral cortex and dorsal hippocampus. Eur J Neurosci 2001 0.89
57 Acute and chronic effects of three benzodiazepines in the social interaction anxiety test in mice. Psychopharmacology (Berl) 1979 0.88
58 Methyllycaconitine (MLA) blocks the nicotine evoked anxiogenic effect and 5-HT release in the dorsal hippocampus: possible role of alpha7 receptors. Neuropharmacology 2003 0.88
59 Tolerance to the behavioral actions of benzodiazepines. Neurosci Biobehav Rev 1985 0.88
60 Rapid development of tolerance to the sedative effects of lorazepam and triazolam in rats. Psychopharmacology (Berl) 1981 0.88
61 Animal models for predicting clinical efficacy of anxiolytic drugs: social behaviour. Neuropsychobiology 1985 0.88
62 Recovery from lorazepam tolerance and the effects of a benzodiazepine antagonist (RO 15-1788) on the development of tolerance. Psychopharmacology (Berl) 1982 0.88
63 In adolescence, female rats are more sensitive to the anxiolytic effect of nicotine than are male rats. Neuropsychopharmacology 2001 0.87
64 Chlordiazepoxide reduces the generalised anxiety, but not the direct responses, of rats exposed to cat odor. Pharmacol Biochem Behav 1992 0.87
65 What can be learned from the effects of benzodiazepines on exploratory behavior? Neurosci Biobehav Rev 1985 0.87
66 Benzodiazepines reduce gastric ulcers induced in rats by stress. Br J Pharmacol 1981 0.86
67 Caffeine-induced anxiogenesis: the role of adenosine, benzodiazepine and noradrenergic receptors. Pharmacol Biochem Behav 1989 0.86
68 5-HT and anxiety: promises and pitfalls. Pharmacol Biochem Behav 1986 0.86
69 The role of 5-HT1A receptors in mediating the anxiogenic effects of nicotine following lateral septal administration. Eur J Neurosci 2000 0.85
70 Hippocampal and septal injections of nicotine and 8-OH-DPAT distinguish among different animal tests of anxiety. Prog Neuropsychopharmacol Biol Psychiatry 2000 0.85
71 Anxiogenic effects of nicotine in the dorsal hippocampus are mediated by 5-HT1A and not by muscarinic M1 receptors. Neuropharmacology 2000 0.85
72 Behavioural and neurochemical responses of male and female chicks to cat odour. Pharmacol Biochem Behav 1996 0.85
73 Stimulation of nicotinic receptors in the lateral septal nucleus increases anxiety. Eur J Neurosci 1999 0.84
74 Responders and nonresponders to cat odor do not differ in other tests of anxiety. Pharmacol Biochem Behav 1994 0.84
75 Cold restraint alters dopamine metabolism in frontal cortex, nucleus accumbens and neostriatum. Physiol Behav 1983 0.84
76 The effects of tricyclic and 'atypical' antidepressants on spontaneous locomotor activity in rodents. Neurosci Biobehav Rev 1986 0.83
77 Changes in tonic immobility and the GABA-benzodiazepine system in response to handling in the chick. Pharmacol Biochem Behav 1997 0.83
78 Benzodiazepines reduce stress-augmented increase in rat urine monoamine oxidase inhibitor. Nature 1981 0.83
79 The effects of putative anxiogenic compounds (FG 7142, CGS 8216 and Ro 15-1788) on the rat corticosterone response. Physiol Behav 1985 0.83
80 The sensitivity of the rat corticosterone response to environmental manipulations and to chronic chlordiazepoxide treatment. Physiol Behav 1980 0.83
81 Contrasting behavioural effects of 8-OH DPAT in the dorsal raphé nucleus and ventral hippocampus. Neuropharmacology 1994 0.83
82 Cognitive impairments of alcoholic cirrhotic patients: correlation with endogenous benzodiazepine receptor ligands and increased affinity of platelet receptors. J Neurol Neurosurg Psychiatry 1996 0.83
83 5,7-dihydroxytryptamine lesions of dorsal and median raphé nuclei and performance in the social interaction test of anxiety and in a home-cage aggression test. J Affect Disord 1979 0.83
84 Dose tolerance to lorazepam develop with once weekly dosing? Br J Clin Pharmacol 1983 0.83
85 Reversal of increased anxiety during benzodiazepine withdrawal: evidence for an anxiogenic endogenous ligand for the benzodiazepine receptor. Brain Res Bull 1988 0.83
86 Does the sedation resulting from sleep deprivation and lorazepam cause similar cognitive deficits? Pharmacol Biochem Behav 1998 0.83
87 Sex differences in benzodiazepine binding in the frontal cortex and amygdala of the rat 24 hours after restraint stress. Neurosci Lett 1996 0.83
88 Raised [3H]-5-HT release and 45Ca2+ uptake in diazepam withdrawal: inhibition by baclofen. Pharmacol Biochem Behav 1992 0.82
89 Are the anxiogenic effects of yohimbine mediated by its action at benzodiazepine receptors? Neurosci Lett 1985 0.82
90 The locus coeruleus noradrenergic system--evidence against a role in attention, habituation, anxiety and motor activity. Brain Res 1978 0.82
91 Selective neurotoxin lesions of the lateral septum: changes in social and aggressive behaviours. Pharmacol Biochem Behav 1982 0.82
92 The effects of yohimbine on exploratory and locomotor behaviour are attributable to its effects at noradrenaline and not at benzodiazepine receptors. Neuropharmacology 1986 0.82
93 Do different mechanisms underlie two anxiogenic effects of systemic nicotine? Behav Pharmacol 2003 0.81
94 The nature of lorazepam-induced amnesia. Psychopharmacology (Berl) 1984 0.81
95 Behavioral consequences of antidepressant treatment in rodents. Neurosci Biobehav Rev 1986 0.81
96 Performance impairment and increased anxiety resulting from the combination of alcohol and lorazepam. J Clin Psychopharmacol 1983 0.81
97 Effects of chlorpromazine on exploration and habituation in the rat. Br J Pharmacol 1973 0.81
98 Increased 5-HT release mediates the anxiogenic response during benzodiazepine withdrawal: a review of supporting neurochemical and behavioural evidence. Psychopharmacology (Berl) 1993 0.81
99 Is benzodiazepine-induced amnesia due to deactivation of the left prefrontal cortex? Psychopharmacology (Berl) 2000 0.81
100 Social isolation modifies nicotine's effects in animal tests of anxiety. Br J Pharmacol 2001 0.81
101 Behavioural pharmacology of benzodiazepines. Prog Neuropsychopharmacol Biol Psychiatry 1984 0.81
102 Chlordiazepoxide loses its anxiolytic action with long-term treatment. Psychopharmacology (Berl) 1979 0.80
103 Effects of the beta-carboline, FG 7142, in the social interaction test of anxiety and the holeboard: correlations between behaviour and plasma concentrations. Pharmacol Biochem Behav 1985 0.80
104 Measures of anxiety and stress in the rat following chronic treatment with yohimbine. J Psychopharmacol 1988 0.80
105 The behavioural effects of lorazepam are poorly related to its concentration in the brain. Life Sci 1983 0.80
106 An investigation of the role of the locus coeruleus in anxiety and agonistic behaviour. Brain Res 1979 0.80
107 Acute handling stress downregulates benzodiazepine receptors: reversal by diazepam. Eur J Pharmacol 1992 0.80
108 Anxiolytic actions of the substance P (NK1) receptor antagonist L-760735 and the 5-HT1A agonist 8-OH-DPAT in the social interaction test in gerbils. Brain Res 2001 0.80
109 The anxiogenic action of Ro 15-1788 is reversed by chronic, but not by acute, treatment with chlordiazepoxide. Brain Res 1984 0.79
110 The effects of neonatal administration of clonazepam on passive avoidance and on social, aggressive and exploratory behavior of adolescent male rats. Neurobehav Toxicol Teratol 1987 0.79
111 The ontogeny of exploration in the rat: habituation and effects of handling. Dev Psychobiol 1978 0.79
112 Evidence against oppositional and pharmacokinetic mechanisms of tolerance to diazepam's sedative effects. Brain Res 1996 0.79
113 Sodium phenobarbitone reverses the anxiogenic effects of compounds acting at three different central sites. Neuropharmacology 1989 0.79
114 Development of tolerance to nicotine's anxiogenic effect in the social interaction test. Brain Res 2001 0.79
115 Effects of time of day and food deprivation on exploratory activity in the rat. Anim Behav 1972 0.79
116 Interactions of ethyl-beta-carboline-3-carboxylate and Ro 15-1788 with CGS 8216 in an animal model of anxiety. Neurosci Lett 1983 0.79
117 Prenatal treatment with clomipramine: effects on the behaviour of male and female adolescent rats. Psychopharmacology (Berl) 1984 0.79
118 Anxiety conditioned to nicotine in the elevated plus-maze is time dependent. Behav Pharmacol 2002 0.79
119 A comparison of the effects of lorazepam with those of propranolol on experimentally-induced anxiety and performance. Br J Clin Pharmacol 1985 0.79
120 Quinolines and anxiety: anxiogenic effects of CGS 8216 and partial anxiolytic profile of PK 9084. Pharmacol Biochem Behav 1983 0.79
121 Potentiation of the effects of chlorpromazine on exploration in the rat by a prior experience of the drug. Psychopharmacologia 1973 0.78
122 Gincosan (a combination of Ginkgo biloba and Panax ginseng): the effects on mood and cognition of 6 and 12 weeks' treatment in post-menopausal women. Nutr Neurosci 2005 0.78
123 The sedative effects of CL 218,872, like those of chlordiazepoxide, are reversed by benzodiazepine antagonists. Psychopharmacology (Berl) 1985 0.78
124 The stress of intruding: reduction by chlordiazepoxide. Physiol Behav 1984 0.78
125 Habituation and generalization of phobic responses to cat odor. Brain Res Bull 1994 0.78
126 Inter-stimulus interval and the rate of behavioural habituation. Q J Exp Psychol 1973 0.78
127 The effects of PK 11195, a ligand for benzodiazepine binding sites, in animal tests of anxiety and stress. Pharmacol Biochem Behav 1985 0.78
128 Different treatment regimens and the development of tolerance to nicotine's anxiogenic effects. Pharmacol Biochem Behav 2001 0.78
129 Functional tolerance to lorazepam in the rat. Psychopharmacology (Berl) 1983 0.78
130 Exploratory behaviour and aversive thresholds in rats following microinjection of morphine into central and medial nuclei of the amygdala [proceedings]. Br J Pharmacol 1979 0.78
131 Flumazenil: a possible treatment for benzodiazepine withdrawal anxiety. Lancet 1987 0.78
132 Pro- and anti-convulsant properties of PK 11195, a ligand for benzodiazepine binding sites: development of tolerance. Br J Pharmacol 1984 0.78
133 Chronic treatment with Ro 15-1788 distinguishes between its benzodiazepine antagonist, agonist and inverse agonist properties. Psychopharmacology (Berl) 1986 0.78
134 Oestrogen receptor-beta and neurohypophysial hormones: functional interaction and neuroanatomical localisation. Pharmacol Biochem Behav 2003 0.78
135 The effects of p-chlorophenylalanine and ethanolamine-O-sulphate in an animal test of anxiety. J Pharm Pharmacol 1977 0.78
136 A comparison of rat brain amino acid and monoamine content in diazepam withdrawal and after exposure to a phobic stimulus. Br J Pharmacol 1993 0.78
137 The anxiogenic action of FG 7142 in the social interaction test is reversed by chlordiazepoxide and Ro 15-1788 but not by CGS 8216. Arch Int Pharmacodyn Ther 1984 0.78
138 The anxiogenic action of Ro 5-4864 is reversed by phenytoin. Neurosci Lett 1983 0.78
139 Kindling induced by pentylenetetrazole in rats is not directly associated with changes in the expression of NMDA or benzodiazepine receptors. Pharmacol Biochem Behav 2000 0.78
140 Partial anxiolytic action of morphine sulphate following microinjection into the central nucleus of the amygdala in rats. Pharmacol Biochem Behav 1979 0.78
141 Kindling with the beta-carboline FG7142 suggests separation between changes in seizure threshold and anxiety-related behaviour. Neuropsychobiology 1988 0.78
142 Chronic diazepam treatment in rats causes long-lasting changes in central [3H]-5-hydroxytryptamine and [14C]-gamma-aminobutyric acid release. Br J Pharmacol 1990 0.78
143 Effects of a single or repeated administration of the benzodiazepine inverse agonist FG7142 on behaviour and cortical adrenoceptor binding in the rat. Psychopharmacology (Berl) 1989 0.78
144 ACTH, but not corticosterone impairs habituation and reduces exploration. Pharmacol Biochem Behav 1978 0.78
145 Behavioural actions of Ro 5-4864: a peripheral-type benzodiazepine? Life Sci 1984 0.78
146 Chemical lesions of both dorsal and median raphe nuclei and changes in social and aggressive behaviour in rats. Pharmacol Biochem Behav 1980 0.77
147 Effects of nicotine and a cannabinoid receptor agonist on negative contrast: distinction between anxiety and disappointment? Psychopharmacology (Berl) 2004 0.77
148 Proconvulsant action of CGS 8216. Neurosci Lett 1983 0.77
149 Effects of neonatal administration of diazepam and lorazepam on performance of adolescent rats in tests of anxiety, aggression, learning and convulsions. Neurobehav Toxicol Teratol 1986 0.77
150 RO5-4864, a ligand for benzodiazepine micromolar and peripheral binding sites: antagonism and enhancement of behavioural effects. Psychopharmacology (Berl) 1983 0.77
151 Depletion in amygdaloid 5-hydroxytryptamine concentration and changes in social and aggressive behaviour. J Neural Transm 1981 0.77
152 Behavioural and biochemical measures of stress in hooded rats from different sources. Physiol Behav 1979 0.77
153 Intraventricular ACTH reduces social interaction in male rats. Pharmacol Biochem Behav 1980 0.77
154 The rat corticosterone response: habituation and modification by chlordiazepoxide. Physiol Behav 1982 0.77
155 Chlordiazepoxide-induced ataxia, muscle relaxation and sedation in the rat: effects of muscimol, picrotoxin and naloxone. Pharmacol Biochem Behav 1982 0.77
156 Are there changes in sensitivity to 5-HT3 receptor ligands following chronic diazepam treatment? Psychopharmacology (Berl) 1992 0.77
157 Exploratory behaviour and aversive thresholds following intra-amygdaloid application of opiates in rats. Pharmacol Biochem Behav 1979 0.77
158 Diazepam and caffeine administration during the first week of life: changes in neonatal and adolescent behavior. Neurotoxicol Teratol 1987 0.77
159 Specificity and savings of behavioural habituation over a series of intra- and inter-modal stimuli. Q J Exp Psychol 1972 0.77
160 The validation of animal tests of anxiety--pharmacological implications. Pol J Pharmacol Pharm 1985 0.77
161 Are lorazepam-induced deficits in attention similar to those resulting from aging? J Clin Psychopharmacol 2001 0.76
162 Flumazenil prevents the development of chlordiazepoxide withdrawal in rats tested in the social interaction test of anxiety. Psychopharmacology (Berl) 1989 0.76
163 The effect of chlordiazepoxide on the habituation of exploration: interactions with the benzodiazepine antagonist RO 15-1788. Pharmacol Biochem Behav 1987 0.76
164 Behavioural effects of pentylenetetrazole reversed by chlordiazepoxide and enhanced by RO 15-1788. Naunyn Schmiedebergs Arch Pharmacol 1984 0.76
165 Effects of parachlorophenylalanine and amphetamine on habituation of exploration. Pharmacol Biochem Behav 1977 0.76
166 Effects of N,N-dimethyltryptamine on behavioural habituation in the rat. Pharmacol Biochem Behav 1977 0.76
167 Effects of chlordiazepoxide on competition for a preferred food in the rat. Behav Brain Res 1986 0.76
168 Benzodiazepines increase preprocholecystokinin messenger RNA levels in rat brain. Eur J Pharmacol 1993 0.76
169 Naloxone reduces social and exploratory activity in the rat. Psychopharmacology (Berl) 1980 0.76
170 Chronic neonatal treatment with CGS 8216: effects on the behaviour of adolescent rats. Behav Brain Res 1984 0.76
171 Actions of the beta-carboline ZK 93426 in an animal test of anxiety and the holeboard: interactions with Ro 15-1788. J Neural Transm 1986 0.76
172 Interactions of two phenylquinolines with picrotoxin and benzodiazepines in vivo and in vitro. Eur J Pharmacol 1984 0.76
173 Are central cholinergic paths involved in habituation of exploration and distraction? Pharmacol Biochem Behav 1976 0.76
174 Piracetam--a non-sedative anxiolytic drug? [proceedings]. Br J Pharmacol 1978 0.76
175 Dizocilpine does not prevent the development of tolerance to the anxiolytic effects of diazepam in rats. Brain Res 1999 0.76
176 Diazepam reverses the effects of pentylenetetrazole in rat pups by acting at type 2 benzodiazepine receptors. Pharmacol Biochem Behav 1989 0.76
177 Repeated electroconvulsive shock has no specific anxiolytic effect but reduces social interaction and exploration in rats. Neuropharmacology 1984 0.76
178 Exploration in immature rats: effects of drugs. Dev Psychobiol 1978 0.76
179 Profiles of the antipanic compounds, triazolobenzodiazepines and phenelzine, in two animal tests of anxiety. Psychiatry Res 1988 0.76
180 Tolerance to midazolam's anxiolytic effects after short-term nicotine treatment. Neuropharmacology 2001 0.76
181 Behavioral changes persisting into adulthood after neonatal benzodiazepine administration in the rat. Neurobehav Toxicol Teratol 1987 0.76
182 Chlordiazepoxide enhances the anxiogenic action of CGS 8216 in the social interaction test: evidence for benzodiazepine withdrawal? Pharmacol Biochem Behav 1985 0.75
183 Prenatal treatment with clomipramine has an anxiolytic profile in the adolescent rat. Physiol Behav 1983 0.75
184 Effects of acute and chronic treatment on the pro- and anti-convulsant actions of CL 218, 872, PK 8165 and PK 9084, putative ligands for the benzodiazepine receptor. J Pharm Pharmacol 1985 0.75
185 Is tofisopam an atypical anxiolytic? Neurosci Biobehav Rev 1986 0.75
186 Amnesic and anxiolytic effects of intravenous diazepam in dental anxiety. Int Clin Psychopharmacol 1986 0.75
187 A rat model of spontaneous myopathy and malignant hyperthermia. Am J Pathol 1998 0.75
188 Evidence for simultaneous anxiolytic and aversive effects several hours after administration of sodium phenobarbitone to the rat. Neuropsychobiology 1988 0.75
189 The effects of 5,7-dihydroxytryptamine lesions of the median and of the dorsal raphe nuclei on social interaction in the rat [proceedings]. Br J Pharmacol 1979 0.75
190 The use of temazepam elixir in surgical dental sedation: a comparison with intravenous midazolam. Br Dent J 1992 0.75
191 Social and exploratory behaviour in the rat after septal administration of ORG 2766 and ACTH4-10. Psychoneuroendocrinology 1983 0.75
192 Exploration, distraction, and habituation in rats reared in isolation. Dev Psychobiol 1978 0.75
193 Diazepam withdrawal increases [3H]-5-HT release from rat amygdaloid slices. Pharmacol Biochem Behav 1994 0.75
194 Flumazenil-precipitated panic and dysphoria in patients dependent on benzodiazepines: a possible aid to abstinence. J Psychopharmacol 1996 0.75
195 Ascending 5-HT pathways and behavioural habituation. Pharmacol Biochem Behav 1979 0.75
196 Evidence that the beta-carboline, ZK 91296, can reduce anxiety in animals at doses well below those causing sedation. Brain Res 1986 0.75
197 Pro- and anti-convulsant drug effects in combination with the convulsant benzodiazepine Ro 5-4864. J Pharm Pharmacol 1985 0.75
198 Effects of stimulus duration and intensity on the rate and specificity of behavioural habituation. Q J Exp Psychol 1973 0.75
199 Does the behavioural activation detected after a single dose of a benzodiazepine reflect a withdrawal response? Life Sci 1988 0.75
200 Receptor binding in Japanese quail selected for long or short tonic immobility. Pharmacol Biochem Behav 1994 0.75
201 Methods for the determination of lorazepam and chlordiazepoxide and metabolites in brain tissue. A comparison with plasma concentrations in the rat. J Chromatogr 1983 0.75
202 Naloxone changes self-ratings but not performance in normal subjects. Psychopharmacology (Berl) 1981 0.75
203 Concurrent treatment with verapamil prevents diazepam withdrawal-induced anxiety, in the absence of altered calcium flux in cortical synaptosomes. Neuropharmacology 1992 0.75
204 Behavioural effects of PK 8165 that are not mediated by benzodiazepine binding sites. Neurosci Lett 1984 0.75
205 Effects of a piperazine derivative piribedil, on exploration, locomotor activity and social behaviour in the rat. Prog Neuropsychopharmacol 1981 0.75
206 Do the intrinsic actions of benzodiazepine receptor antagonists imply the existence of an endogenous ligand for benzodiazepine receptors? Adv Biochem Psychopharmacol 1986 0.75
207 Strain differences in mice in the development of tolerance to the anti-pentylenetetrazole effects of diazepam. Neurosci Lett 1983 0.75
208 The effects of the beta-carboline FG 7142, on intracranial self-stimulation in the rat. Pharmacol Biochem Behav 1984 0.75
209 Piracetam impairs the overshadowing of background stimuli by an informative CS. Physiol Behav 1979 0.75
210 Effects of ACTH4--10 in the social interaction test of anxiety. Brain Res 1979 0.75
211 Lasting behavioral effects after treating rats with CGS 8216 on postnatal days 9 to 21. Physiol Behav 1984 0.75
212 Poor bioavailability of CGS 8216 in a water/tween vehicle following intraperitoneal injection. Psychopharmacology (Berl) 1987 0.75
213 Acquisition and retention of habituation in the preweanling rat. Dev Psychobiol 1976 0.75
214 Caffeine interactions with multiple neurotransmitter systems. Trends Pharmacol Sci 1988 0.75
215 Output of endogenous monoamine oxidase inhibitor in rats: effect of ethanol, tryptamine and tryptophan. J Neural Transm 1983 0.75
216 The effects of putative anxiolytic compounds (PK 8165, PK 9084 and tracazolate) on the rat corticosterone response. Physiol Behav 1985 0.75
217 Regulation of glutamate decarboxylase and enkephalin mRNA levels in rat striatum by chronic benzodiazepine treatment. Biochem Soc Trans 1992 0.75
218 Benzodiazepines and behavior. Neurosci Biobehav Rev 1985 0.75
219 Long-lasting anticonvulsant effects of diazepam in different mouse strains: correlations with brain concentrations and receptor occupancy. Psychopharmacology (Berl) 1985 0.75
220 beta-CCE and chlordiazepoxide reduce exploratory head-dipping and rearing: no mutual antagonism. Neuropharmacology 1982 0.75
221 A pharmacokinetic study of CGS-8216, a benzodiazepine receptor ligand, in the rat. Psychopharmacology (Berl) 1984 0.75
222 Triazolobenzodiazepines antagonize the effects of anxiogenic drugs mediated at three different central nervous system sites. Neurosci Lett 1985 0.75
223 Exploration and motor activity after intraventricular ACTH, morphine and naloxone. Behav Brain Res 1981 0.75
224 Prenatal influences on the responsivity of neonate rats. Behav Biol 1976 0.75
225 Anticonvulsant effects of chronic treatment with phenytoin against pentylenetetrazole-induced seizures in the mouse. Neuropharmacology 1985 0.75
226 The anxiolytic but not the sedative properties of tracazolate are reversed by the benzodiazepine receptor antagonist, Ro 15-1788. Neuropsychobiology 1985 0.75
227 Effects of parachlorophenylalanine and amphetamine on habituation of orienting. Pharmacol Biochem Behav 1976 0.75
228 Infundibular ACTH can be excluded as a critical mediator in social behaviours. Brain Res Bull 1981 0.75
229 Antagonism of the effects of the atypical benzodiazepine, Ro 5-4864 on intracranial self-stimulation in the rat. Pharmacol Biochem Behav 1986 0.75
230 Anxiogenic action of a convulsant benzodiazepine: reversal by chlordiazepoxide. Brain Res 1983 0.75
231 The anxiogenic action of RO 5-4864 in the social interaction test: effect of chlordiazepoxide, RO 15-1788 and CGS 8216. Naunyn Schmiedebergs Arch Pharmacol 1985 0.75
232 Lorazepam treatment in the neonatal rat alters submissive behavior in adulthood. Neurobehav Toxicol Teratol 1983 0.75
233 Lack of cross-tolerance in mice between the stimulatory and depressant actions of novel anxiolytics in the holeboard. Behav Brain Res 1987 0.75
234 Behavioral effects of lesions of the locus ceruleus noradrenaline system combined with adrenalectomy. Behav Neural Biol 1979 0.75
235 Evidence that piracetam has an anxiolytic action. J Affect Disord 1979 0.75
236 Interaction between prior experience and the effects of chlorpromazine on exploration in the rat. Psychopharmacologia 1973 0.75
237 Effect on hypothalamic self-stimulation of the novel beta-carbolines ZK 93 426 (a benzodiazepine receptor antagonist) and ZK 91 296 (a putative partial agonist). J Neural Transm 1986 0.75
238 Neonatal clomipramine treatment in the rat does not affect social, sexual and exploratory behaviors in adulthood. Neurobehav Toxicol Teratol 1983 0.75
239 Intrinsic behavioural actions of n-propyl beta-carboline-3-carboxylate. Neuropharmacology 1984 0.75
240 Flumazenil-precipitated panic and dysphoria in patients dependent on benzodiazepines: a possible aid to abstinence--authors' response. J Psychopharmacol 1996 0.75
241 The effects of benzodiazepines in newborn rats suggest a function for type 2 receptors. Pharmacol Biochem Behav 1986 0.75
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