Preclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing.

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Published in Mol Ther Methods Clin Dev on May 11, 2017

Authors

Karine Cambon1,2, Virginie Zimmer3,4, Sylvain Martineau1,2, Marie-Claude Gaillard1,2, Margot Jarrige5,6,7, Aurore Bugi7, Jana Miniarikova8, Maria Rey3,4, Raymonde Hassig1,2, Noelle Dufour1,2, Gwenaelle Auregan1,2, Philippe Hantraye1,2, Anselme L Perrier5,6, Nicole Déglon3,4

Author Affiliations

1: CEA, DRF, Institute of Biology Francois Jacob, Molecular Imaging Research Center, F-92265 Fontenay-aux-Roses, France.
2: CNRS, CEA, Paris-Sud University, University Paris-Saclay, Neurodegenerative Diseases Laboratory (UMR9199), F-92265 Fontenay-aux-Roses, France.
3: Department of Clinical Neurosciences, Laboratory of Cellular and Molecular Neurotherapies, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland.
4: Neuroscience Research Center, Laboratory of Cellular and Molecular Neurotherapies, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland.
5: Institut National de la Santé et de la Recherche Médicale UMR861, I-Stem, AFM, 91100 Corbeil-Essonnes, France.
6: UEVE UMR861, I-STEM, AFM, 91100 Corbeil-Essonnes, France.
7: CECS, I-STEM, AFM, 91100 Corbeil-Essonnes, France.
8: Department of Research & Development, uniQure, 1105 Amsterdam, the Netherlands.

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