Synergy of Iron Chelators and Therapeutic Peptide Sequences Delivered via a Magnetic Nanocarrier.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28672849)

Published in J Funct Biomater on June 26, 2017

Authors

Gayani S Abayaweera1, Hongwang Wang2, Tej B Shrestha3, Jing Yu4, Kyle Angle5, Prem Thapa6, Aruni P Malalasekera7, Leila Maurmann8, Deryl L Troyer9, Stefan H Bossmann10

Author Affiliations

1: Department of Chemistry, Kansas State University, Manhattan, KS 66041, USA. gsa2014a@gmail.com.
2: Department of Chemistry, Kansas State University, Manhattan, KS 66041, USA. hongwang@ksu.edu.
3: tbs3@ksu.edu (T.B.S.). yujing0415@ksu.edu.
4: Department of Chemistry, Kansas State University, Manhattan, KS 66041, USA. kja2665@truman.edu.
5: Department of Chemistry, Kansas State University, Manhattan, KS 66041, USA. aruni@ksu.edu.
6: Microscopy and Analytical Imaging Laboratory, University of Kansas, Lawrence, KS 66045, USA. leila76@ksu.edu.
7: Department of Chemistry, Kansas State University, Manhattan, KS 66041, USA. troyer@vet.k-state.edu.
8: Department of Chemistry, Kansas State University, Manhattan, KS 66041, USA. psthapa@ku.edu.
9: tbs3@ksu.edu (T.B.S.). troyer@vet.k-state.edu.
10: Department of Chemistry, Kansas State University, Manhattan, KS 66041, USA. sbossman@ksu.edu.

Articles cited by this

Cancer Statistics, 2017. CA Cancer J Clin (2017) 4.77

Anti-cancer activity of targeted pro-apoptotic peptides. Nat Med (1999) 3.72

Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles. J Am Chem Soc (2004) 2.54

Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma. Cancer Cell (2003) 2.07

Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma. Proc Natl Acad Sci U S A (2011) 1.68

Peptide coupling reagents, more than a letter soup. Chem Rev (2011) 1.58

Determination of peptide substrate specificity for mu-calpain by a peptide library-based approach: the importance of primed side interactions. J Biol Chem (2005) 1.44

The iron chelator Dp44mT causes DNA damage and selective inhibition of topoisomerase IIalpha in breast cancer cells. Cancer Res (2009) 1.17

A/C magnetic hyperthermia of melanoma mediated by iron(0)/iron oxide core/shell magnetic nanoparticles: a mouse study. BMC Cancer (2010) 1.17

Design of a tumor-homing cell-penetrating peptide. Bioconjug Chem (2007) 1.06

Nanoparticles in magnetic resonance imaging: from simple to dual contrast agents. Int J Nanomedicine (2015) 1.02

Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics. Biochim Biophys Acta (2016) 0.93

Magnetic-Fe/Fe(3)O(4)-nanoparticle-bound SN38 as carboxylesterase-cleavable prodrug for the delivery to tumors within monocytes/macrophages. Beilstein J Nanotechnol (2012) 0.92

Attenuation of mouse melanoma by A/C magnetic field after delivery of bi-magnetic nanoparticles by neural progenitor cells. ACS Nano (2010) 0.91

The iron complex of Dp44mT is redox-active and induces hydroxyl radical formation: an EPR study. J Inorg Biochem (2010) 0.91

Iron and cancer: recent insights. Ann N Y Acad Sci (2016) 0.86

Heterocyclic dithiocarbazate iron chelators: Fe coordination chemistry and biological activity. Dalton Trans (2012) 0.85

To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine? J Control Release (2016) 0.81

Nanoplatforms for highly sensitive fluorescence detection of cancer-related proteases. Photochem Photobiol Sci (2014) 0.80

Enhanced targeting of mitochondrial peroxide defense by the combined use of thiosemicarbazones and inhibitors of thioredoxin reductase. Free Radic Biol Med (2015) 0.79

The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells. Biochim Biophys Acta (2016) 0.78

Potent retro-inverso D-peptide for simultaneous targeting of angiogenic blood vasculature and tumor cells. Bioconjug Chem (2013) 0.78

Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase. Biochem Pharmacol (2016) 0.78

Early breast cancer screening using iron/iron oxide-based nanoplatforms with sub-femtomolar limits of detection. Beilstein J Nanotechnol (2016) 0.77