Published in Proc Natl Acad Sci U S A on February 01, 1986
Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes. Nucleic Acids Res (1989) 10.03
Finding sequence motifs in groups of functionally related proteins. Proc Natl Acad Sci U S A (1990) 7.65
Mutations in human dynamin block an intermediate stage in coated vesicle formation. J Cell Biol (1993) 7.37
Expression of sigma 54 (ntrA)-dependent genes is probably united by a common mechanism. Microbiol Rev (1989) 7.22
Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A. EMBO J (1992) 6.16
GTP-binding domain: three consensus sequence elements with distinct spacing. Proc Natl Acad Sci U S A (1987) 5.16
The sigma 54 bacterial enhancer-binding protein family: mechanism of action and phylogenetic relationship of their functional domains. J Bacteriol (1993) 4.34
Viral proteins containing the purine NTP-binding sequence pattern. Nucleic Acids Res (1989) 3.96
Surface presentation of Shigella flexneri invasion plasmid antigens requires the products of the spa locus. J Bacteriol (1992) 3.91
Deduced products of C4-dicarboxylate transport regulatory genes of Rhizobium leguminosarum are homologous to nitrogen regulatory gene products. Nucleic Acids Res (1987) 3.66
Cytoplasmic dynein and actin-related protein Arp1 are required for normal nuclear distribution in filamentous fungi. J Cell Biol (1994) 3.60
Mutation of lysine-48 to arginine in the yeast RAD3 protein abolishes its ATPase and DNA helicase activities but not the ability to bind ATP. EMBO J (1988) 3.43
Nucleotide sequence and genetic organization of the Bacillus subtilis comG operon. J Bacteriol (1989) 3.18
The secreted hemolysins of Proteus mirabilis, Proteus vulgaris, and Morganella morganii are genetically related to each other and to the alpha-hemolysin of Escherichia coli. J Bacteriol (1987) 3.13
Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome. Mol Cell Biol (1992) 3.12
YscN, the putative energizer of the Yersinia Yop secretion machinery. J Bacteriol (1994) 3.12
CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis. J Cell Biol (1995) 3.03
ScII: an abundant chromosome scaffold protein is a member of a family of putative ATPases with an unusual predicted tertiary structure. J Cell Biol (1994) 2.98
Molecular and functional characterization of the Salmonella typhimurium invasion genes invB and invC: homology of InvC to the F0F1 ATPase family of proteins. J Bacteriol (1994) 2.80
Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression. J Cell Biol (1991) 2.79
Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein. Mol Cell Biol (1996) 2.78
The yeast RAD50 gene encodes a predicted 153-kD protein containing a purine nucleotide-binding domain and two large heptad-repeat regions. Genetics (1989) 2.63
Binary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteins. Microbiol Mol Biol Rev (2004) 2.60
An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF. EMBO J (1990) 2.60
Dynein from Dictyostelium: primary structure comparisons between a cytoplasmic motor enzyme and flagellar dynein. J Cell Biol (1992) 2.37
Altering the conserved nucleotide binding motif in the Salmonella typhimurium MutS mismatch repair protein affects both its ATPase and mismatch binding activities. EMBO J (1991) 2.34
Characterization of yeast Vps33p, a protein required for vacuolar protein sorting and vacuole biogenesis. Mol Cell Biol (1990) 2.32
Translation initiation factor 4A from Saccharomyces cerevisiae: analysis of residues conserved in the D-E-A-D family of RNA helicases. Mol Cell Biol (1991) 2.27
Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance. Mol Cell Biol (1989) 2.18
Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens. Proc Natl Acad Sci U S A (1987) 2.15
Pseudomonas aeruginosa AlgB, a two-component response regulator of the NtrC family, is required for algD transcription. J Bacteriol (1991) 2.13
Analysis of the complete nucleotide sequence of the Agrobacterium tumefaciens virB operon. Nucleic Acids Res (1988) 2.13
Cloning of the yeast FAS3 gene and primary structure of yeast acetyl-CoA carboxylase. Proc Natl Acad Sci U S A (1992) 2.10
Conserved protein domains in a myosin heavy chain gene from Dictyostelium discoideum. Proc Natl Acad Sci U S A (1986) 2.05
Nucleotide sequencing of the ruv region of Escherichia coli K-12 reveals a LexA regulated operon encoding two genes. Nucleic Acids Res (1988) 2.03
Mutations in DNA gyrase result in novobiocin resistance in halophilic archaebacteria. J Bacteriol (1991) 2.03
Repression of gene expression by an exogenous sequence element acting in concert with a heterogeneous nuclear ribonucleoprotein-like protein, Nrd1, and the putative helicase Sen1. Mol Cell Biol (1996) 2.02
Cloning and sequencing of the PIF gene involved in repair and recombination of yeast mitochondrial DNA. EMBO J (1987) 1.97
Structural model of the nucleotide-binding conserved component of periplasmic permeases. Proc Natl Acad Sci U S A (1991) 1.92
Cloning and characterization of DST2, the gene for DNA strand transfer protein beta from Saccharomyces cerevisiae. Mol Cell Biol (1991) 1.88
Active site comparisons highlight structural similarities between myosin and other P-loop proteins. Biophys J (1996) 1.80
Respiration and mitochondrial biogenesis in germinating embryos of maize. Plant Physiol (1990) 1.80
mei-1, a gene required for meiotic spindle formation in Caenorhabditis elegans, is a member of a family of ATPases. Genetics (1994) 1.79
The transcriptional regulator LevR of Bacillus subtilis has domains homologous to both sigma 54- and phosphotransferase system-dependent regulators. Proc Natl Acad Sci U S A (1991) 1.76
RAD25 (SSL2), the yeast homolog of the human xeroderma pigmentosum group B DNA repair gene, is essential for viability. Proc Natl Acad Sci U S A (1992) 1.75
Analysis of mitotic and meiotic defects in Saccharomyces cerevisiae SRS2 DNA helicase mutants. Genetics (1992) 1.72
Agrobacterium tumefaciens VirB11 protein requires a consensus nucleotide-binding site for function in virulence. J Bacteriol (1995) 1.72
Identification of pilR, which encodes a transcriptional activator of the Pseudomonas aeruginosa pilin gene. J Bacteriol (1992) 1.62
Complete nucleotide sequence of recD, the structural gene for the alpha subunit of Exonuclease V of Escherichia coli. Nucleic Acids Res (1986) 1.62
Structure of rho factor: an RNA-binding domain and a separate region with strong similarity to proven ATP-binding domains. Proc Natl Acad Sci U S A (1988) 1.58
The six conserved helicase motifs of the UL5 gene product, a component of the herpes simplex virus type 1 helicase-primase, are essential for its function. J Virol (1992) 1.54
Altered cobalamin metabolism in Escherichia coli btuR mutants affects btuB gene regulation. J Bacteriol (1989) 1.54
Comparative analysis of editosome proteins in trypanosomatids. Nucleic Acids Res (2003) 1.52
ATP is a cofactor of the Upf1 protein that modulates its translation termination and RNA binding activities. RNA (1998) 1.50
The conserved helicase motifs of the herpes simplex virus type 1 origin-binding protein UL9 are important for function. J Virol (1992) 1.47
An HlyB-type function is required for expression of the Enterococcus faecalis hemolysin/bacteriocin. Infect Immun (1990) 1.46
A lysine substitution in the ATP-binding site of eucaryotic initiation factor 4A abrogates nucleotide-binding activity. Mol Cell Biol (1989) 1.43
Molecular analysis of the Escherichia coli recO gene. J Bacteriol (1989) 1.43
ATP requirement for Prp5p function is determined by Cus2p and the structure of U2 small nuclear RNA. Proc Natl Acad Sci U S A (2003) 1.43
BCS1, a novel gene required for the expression of functional Rieske iron-sulfur protein in Saccharomyces cerevisiae. EMBO J (1992) 1.38
MgATP binding and hydrolysis determinants of NtrC, a bacterial enhancer-binding protein. J Bacteriol (1999) 1.38
Rotavirus SA11 genome segment 11 protein is a nonstructural phosphoprotein. J Virol (1989) 1.37
P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity. Proc Natl Acad Sci U S A (1997) 1.36
HSP78 encodes a yeast mitochondrial heat shock protein in the Clp family of ATP-dependent proteases. Mol Cell Biol (1993) 1.33
Isolation, DNA sequence, and regulation of a Saccharomyces cerevisiae gene that encodes DNA strand transfer protein alpha. Mol Cell Biol (1991) 1.29
Amino acid sequence similarity between GCN3 and GCD2, positive and negative translational regulators of GCN4: evidence for antagonism by competition. Genetics (1989) 1.29
Biochemical and molecular characterization of the oxidative branch of glycerol utilization by Citrobacter freundii. J Bacteriol (1995) 1.28
Cloning by insertional mutagenesis of a cDNA encoding Caenorhabditis elegans kinesin heavy chain. Proc Natl Acad Sci U S A (1993) 1.28
Functional roles of the nucleotide-binding folds in the activation of the cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci U S A (1993) 1.28
Identification of residues essential for catalysis and binding of calmodulin in Bordetella pertussis adenylate cyclase by site-directed mutagenesis. EMBO J (1989) 1.27
Mutations in motif II of Escherichia coli DNA helicase II render the enzyme nonfunctional in both mismatch repair and excision repair with differential effects on the unwinding reaction. J Bacteriol (1995) 1.27
Relation of the Escherichia coli dnaX gene to its two products--the tau and gamma subunits of DNA polymerase III holoenzyme. Nucleic Acids Res (1987) 1.25
Isolation and characterization of the moxJ, moxG, moxI, and moxR genes of Paracoccus denitrificans: inactivation of moxJ, moxG, and moxR and the resultant effect on methylotrophic growth. J Bacteriol (1991) 1.22
Nucleotide binding by a 24-residue peptide from the RecA protein of Escherichia coli. Proc Natl Acad Sci U S A (1986) 1.22
Molecular characterization of a genomic region in a Lactococcus bacteriophage that is involved in its sensitivity to the phage defense mechanism AbiA. J Bacteriol (1997) 1.21
Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis. Biochem J (2002) 1.19
Pyruvate carboxylase from Rhizobium etli: mutant characterization, nucleotide sequence, and physiological role. J Bacteriol (1996) 1.17
Mutations in the Escherichia coli UvrB ATPase motif compromise excision repair capacity. Proc Natl Acad Sci U S A (1989) 1.16
The ggtA gene encodes a subunit of the transport system for the osmoprotective compound glucosylglycerol in Synechocystis sp. strain PCC 6803. J Bacteriol (1997) 1.14
Domain structure of phage P4 alpha protein deduced by mutational analysis. J Bacteriol (1995) 1.13
Overexpression of SIS2, which contains an extremely acidic region, increases the expression of SWI4, CLN1 and CLN2 in sit4 mutants. Genetics (1995) 1.13
Expression of a mutant DNA topoisomerase II in CCRF-CEM human leukemic cells selected for resistance to teniposide. Proc Natl Acad Sci U S A (1991) 1.12
Structural significance of the GTP-binding domain of ras p21 studied by site-directed mutagenesis. Mol Cell Biol (1987) 1.12
Cloning and nucleotide sequence of the gene coding for aspartokinase II from a thermophilic methylotrophic Bacillus sp. Appl Environ Microbiol (1992) 1.11
CFTR: the nucleotide binding folds regulate the accessibility and stability of the activated state. J Gen Physiol (1996) 1.11
Sug1 modulates yeast transcription activation by Cdc68. Mol Cell Biol (1995) 1.11
Distinct roles of the Drosophila ninaC kinase and myosin domains revealed by systematic mutagenesis. J Cell Biol (1993) 1.08
Mutational analysis of ERCC3, which is involved in DNA repair and transcription initiation: identification of domains essential for the DNA repair function. Mol Cell Biol (1994) 1.08
Influence of a mutation in the putative nucleotide binding site of the nitrogen regulatory protein NTRC on its positive control function. Nucleic Acids Res (1991) 1.07
Genetic structure of the dnaA region of the cyanobacterium Synechocystis sp. strain PCC6803. J Bacteriol (1995) 1.04
Structure-function relationships in the GTP binding domain of EF-Tu: mutation of Val20, the residue homologous to position 12 in p21. EMBO J (1988) 1.03
Role of monosaccharide transport proteins in carbohydrate assimilation, distribution, metabolism, and homeostasis. Compr Physiol (2012) 1.01
Adenine nucleotide binding sites on beef heart F1 ATPase: photoaffinity labeling of beta-subunit Tyr-368 at a noncatalytic site and beta Tyr-345 at a catalytic site. Proc Natl Acad Sci U S A (1987) 1.00
Genetic and biochemical characterization of the F-ATPase operon from Streptococcus sanguis 10904. J Bacteriol (2003) 0.98
Effects of insertions and deletions in glnG (ntrC) of Escherichia coli on nitrogen regulator I-dependent DNA binding and transcriptional activation. J Bacteriol (1993) 0.98
Preclinical and clinical pharmacology of vinca alkaloids. Drugs (1992) 0.98
Evolution of the herpes thymidine kinase: identification and comparison of the equine herpesvirus 1 thymidine kinase gene reveals similarity to a cell-encoded thymidylate kinase. Nucleic Acids Res (1988) 0.97
Crystal structure of the BstDEAD N-terminal domain: a novel DEAD protein from Bacillus stearothermophilus. RNA (2004) 0.96
cobU-dependent assimilation of nonadenosylated cobinamide in cobA mutants of Salmonella typhimurium. J Bacteriol (1993) 0.96
Nucleotide sequence analysis of the L gene of Newcastle disease virus: homologies with Sendai and vesicular stomatitis viruses. Nucleic Acids Res (1987) 0.95
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J (1982) 38.14
The anatomy and taxonomy of protein structure. Adv Protein Chem (1981) 16.85
Mechanism of activation of a human oncogene. Nature (1982) 12.09
A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene. Nature (1982) 11.92
The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene. Nucleic Acids Res (1980) 9.96
Comparative biochemical properties of normal and activated human ras p21 protein. Nature (1984) 6.50
Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules. Proc Natl Acad Sci U S A (1984) 6.45
Biological properties of human c-Ha-ras1 genes mutated at codon 12. Nature (1984) 6.21
The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity. Nature (1984) 4.61
Regulation and kinetics of the actin-myosin-ATP interaction. Annu Rev Biochem (1980) 4.57
Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene. Nature (1983) 4.34
Direct evidence that oncogenic tyrosine kinases and cyclic AMP-dependent protein kinase have homologous ATP-binding sites. Nature (1984) 3.91
Homologies between signal transducing G proteins and ras gene products. Science (1984) 3.85
Structure and function of nitrogenase. Annu Rev Biochem (1979) 3.75
Analysis of the transforming potential of the human H-ras gene by random mutagenesis. Proc Natl Acad Sci U S A (1984) 3.64
Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus. Science (1982) 3.55
Homology between human bladder carcinoma oncogene product and mitochondrial ATP-synthase. Nature (1983) 3.34
Nucleotide sequence of the oncogene encoding the p21 transforming protein of Kirsten murine sarcoma virus. Science (1982) 2.94
Sequence, structure and activity of phosphoglycerate kinase: a possible hinge-bending enzyme. Nature (1979) 2.88
Substrate positions and induced-fit in crystalline adenylate kinase. J Mol Biol (1977) 2.69
Sequence and structure of yeast phosphoglycerate kinase. EMBO J (1982) 2.64
Characterization of the phosphorylation sites and the surrounding amino acid sequences of the p21 transforming proteins coded for by the Harvey and Kirsten strains of murine sarcoma viruses. J Biol Chem (1982) 2.59
The nucleotide sequence of the dnaA gene and the first part of the dnaN gene of Escherichia coli K-12. Nucleic Acids Res (1982) 2.41
Phosphofructokinase: structure and control. Philos Trans R Soc Lond B Biol Sci (1981) 2.01
Complete amino acid sequence of rabbit muscle glycogen phosphorylase. Proc Natl Acad Sci U S A (1977) 2.00
Three dimensional structure of adenyl kinase. Nature (1974) 1.88
Autophosphorylation of v-Ha-ras p21 is modulated by amino acid residue 12. Proc Natl Acad Sci U S A (1984) 1.68
The amino-acid sequence of sarcine adenylate kinase from skeletal muscle. Eur J Biochem (1974) 1.54
Proton atpases: structure and mechanism. Annu Rev Biochem (1983) 1.52
Amino acid sequence of the biotinyl subunit from transcarboxylase. J Biol Chem (1979) 1.40
The presence of two hydrolytic sites on beef heart mitochondrial adenosine triphosphatase. J Biol Chem (1981) 1.28
Rabbit muscle creatine phosphokinase. CDNA cloning, primary structure and detection of human homologues. J Biol Chem (1984) 1.24
Sequence analysis of the 17,166 base-pair EcoRI fragment C of B95-8 Epstein-Barr virus. Mol Biol Med (1983) 1.22
Two conformations of crystalline adenylate kinase. J Mol Biol (1977) 1.11
Identification of possible adenine nucleotide-binding sites in nitrogenase Fe- and MoFe-proteins by amino acid sequence comparison. FEBS Lett (1984) 1.10
Studies on adenosine triphosphate transphosphorylases. Amino acid sequence of rabbit muscle ATP-AMP transphosphorylase. Biochemistry (1984) 1.08
Amino acid sequence at the ATP-binding site of cGMP-dependent protein kinase. J Biol Chem (1982) 1.07
NMR studies of the MgATP binding site of adenylate kinase and of a 45-residue peptide fragment of the enzyme. Biochemistry (1985) 1.04
Substrate-cofactor interactions for glycogen phosphorylase b: a binding study in the crystal with heptenitol and heptulose 2-phosphate. Biochemistry (1984) 1.04
Studies of adenosine triphosphate transphosphorylases. XIV. Equilibrium binding properties of the crystalline rabbit and calf muscle ATP--AMP transphosphorylase (adenylate kinase) and derived peptide fragments. Arch Biochem Biophys (1979) 1.02
Transcarboxylase. VII. Exchange reactions and kinetics of oxalate inhibition. J Biol Chem (1969) 1.02
ATP and ADP modulations of catalysis by F1 and Ca2+, Mg2+-ATPases. Ann N Y Acad Sci (1982) 0.98
Nuclear magnetic resonance studies of the nucleotide binding sites of porcine adenylate kinase. Biochemistry (1982) 0.92
Primary and tertiary structure of the principal human adenylate kinase. Eur J Biochem (1976) 0.88
Snake venoms. Purification, some properties and amino acid sequence of a phospholipase A2 (DE-I) from Trimeresurus okinavensis (Hime-habu) venom. Hoppe Seylers Z Physiol Chem (1981) 0.85
Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis. Proc Natl Acad Sci U S A (1981) 4.14
Spinach leaf phosphoenolpyruvate carboxylase: purification, properties, and kinetic studies. Arch Biochem Biophys (1974) 2.46
Zinc in DNA polymerases. Biochem Biophys Res Commun (1971) 2.15
On the fidelity of DNA replication: manganese mutagenesis in vitro. Biochemistry (1985) 1.90
Aspects of enzyme mechanisms studies by nuclear spin relazation induced by paramagnetic probes. Adv Enzymol Relat Areas Mol Biol (1970) 1.90
Kinetic and ultraviolet spectroscopic studies of active-site mutants of delta 5-3-ketosteroid isomerase. Biochemistry (1989) 1.85
Kinetic and magnetic resonance studies of the pyruvate kinase reaction. II. Complexes of enzyme, metal, and substrates. J Biol Chem (1966) 1.79
Environments and mechanistic roles of the tyrosine residues of delta 5-3-ketosteroid isomerase. Biochemistry (1993) 1.53
Kinetic and magnetic resonance studies of active-site mutants of staphylococcal nuclease: factors contributing to catalysis. Biochemistry (1987) 1.46
NMR docking of a substrate into the X-ray structure of staphylococcal nuclease. Proteins (1992) 1.46
Vaccinia DNA topoisomerase I: single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions. Biochemistry (1994) 1.46
Glucose 6-phosphate dehydrogenase from brewers' yeast (Zwischenferment). 3. Studies on the subunit structure and on the molecular association phenomenon induced by triphosphopyridine nucleotide. J Biol Chem (1969) 1.37
Vaccinia DNA topoisomerase I: evidence supporting a free rotation mechanism for DNA supercoil relaxation. Biochemistry (1997) 1.35
NMR evidence for the participation of a low-barrier hydrogen bond in the mechanism of delta 5-3-ketosteroid isomerase. Proc Natl Acad Sci U S A (1996) 1.33
The role of metal ions in the mechanisms of DNA and RNA polymerases. CRC Crit Rev Biochem (1979) 1.33
Stuies on the interaction of substrate and monovalent and divalent cations with pyruvate kinase. Biochemistry (1966) 1.33
Mechanism of malic enzyme from pigeon liver. Magnetic resonance and kinetic studies of the role of Mn2+. J Biol Chem (1976) 1.32
Proton magnetic relaxation studies of the interaction of D-xylose and xylitol with D-xylose isomerase. Characterization of metal-enzyme-substrate interactions. J Biol Chem (1975) 1.27
Kinetic analysis of Escherichia coli deoxyribonucleic acid polymerase I. J Biol Chem (1975) 1.27
The mechanism of aconitase action. I. Preparation, physical properties of the enzyme, and activation by iron (II). J Biol Chem (1971) 1.25
Kinetic and magnetic resonance studies of effects of genetic substitution of a Ca2+-liganding amino acid in staphylococcal nuclease. Biochemistry (1986) 1.24
4-Oxalocrotonate tautomerase: pH dependence of catalysis and pKa values of active site residues. Biochemistry (1996) 1.24
Escherichia coli deoxyribonucleic acid polymerase I, a zinc metalloenzyme. Nuclear quadrupolar relaxation studies of the role of bound zinc. J Biol Chem (1973) 1.24
Conformation of deoxynucleoside triphosphate substrates on DNA polymerase I from Escherichia coli as determined by nuclear magnetic relaxation. J Biol Chem (1975) 1.23
Solution structure of the Ras-binding domain of c-Raf-1 and identification of its Ras interaction surface. Biochemistry (1995) 1.21
The role of Glu 57 in the mechanism of the Escherichia coli MutT enzyme by mutagenesis and heteronuclear NMR. Biochemistry (1996) 1.21
Catalytic role of the amino-terminal proline in 4-oxalocrotonate tautomerase: affinity labeling and heteronuclear NMR studies. Biochemistry (1996) 1.20
The mechanism of Escherichia coli deoxyribonucleic acid polymerase I. Magnetic resonance and kinetic studies of the role of metals. J Biol Chem (1972) 1.17
Solution structure of the MutT enzyme, a nucleoside triphosphate pyrophosphohydrolase. Biochemistry (1995) 1.17
Structures of enzyme-bound metal-nucleotide complexes in the phosphoryl transfer reaction of muscle pyruvate kinase. 31P NMR studies with magnesium and kinetic studies with chromium nucleotides. J Biol Chem (1977) 1.15
Escherichia coli orf17 codes for a nucleoside triphosphate pyrophosphohydrolase member of the MutT family of proteins. Cloning, purification, and characterization of the enzyme. J Biol Chem (1996) 1.13
Electron paramagnetic resonance, 1-H, and 13C nuclear magnetic resonance studies of the interaction of manganese and bicarbonate with ribulose 1, 5-diphosphate carboxylase. J Biol Chem (1974) 1.12
Kinetic and magnetic resonance studies of the mechanism of D-xylose isomerase. I. Binary and ternary complexes with manganese(II), substrates, and inhibitors. J Biol Chem (1972) 1.12
Combined effects of two mutations of catalytic residues on the ketosteroid isomerase reaction. Biochemistry (1990) 1.09
15N NMR relaxation studies of free and inhibitor-bound 4-oxalocrotonate tautomerase: backbone dynamics and entropy changes of an enzyme upon inhibitor binding. Biochemistry (1996) 1.09
Studies of the mechanism of the delta 5-3-ketosteroid isomerase reaction by substrate, solvent, and combined kinetic deuterium isotope effects on wild-type and mutant enzymes. Biochemistry (1990) 1.08
Catalytic mechanism of an active-site mutant (D38N) of delta 5-3-ketosteroid isomerase. Direct spectroscopic evidence for dienol intermediates. Biochemistry (1991) 1.08
Hydrogen bonding at the active site of delta 5-3-ketosteroid isomerase. Biochemistry (1997) 1.08
Studies on adenosine triphosphate transphosphorylases. Amino acid sequence of rabbit muscle ATP-AMP transphosphorylase. Biochemistry (1984) 1.08
Nuclear relaxation measurements of the geometry of enzyme-bound substrates and analogs. Methods Enzymol (1978) 1.07
NMR studies of conformations and interactions of substrates and ribonucleotide templates bound to the large fragment of DNA polymerase I. Biochemistry (1986) 1.07
Vaccinia DNA topoisomerase I: kinetic evidence for general acid-base catalysis and a conformational step. Biochemistry (1994) 1.06
Solution structure of Delta 5-3-ketosteroid isomerase complexed with the steroid 19-nortestosterone hemisuccinate. Biochemistry (1998) 1.06
Nuclear magnetic resonance studies of the function of potassium in the mechanism of pyruvate kinase. Biochemistry (1972) 1.05
High-precision measurement of hydrogen bond lengths in proteins by nuclear magnetic resonance methods. Proteins (1999) 1.05
NMR studies of the role of hydrogen bonding in the mechanism of triosephosphate isomerase. Biochemistry (1997) 1.05
NMR studies of the MgATP binding site of adenylate kinase and of a 45-residue peptide fragment of the enzyme. Biochemistry (1985) 1.04
Mutational, kinetic, and NMR studies of the roles of conserved glutamate residues and of lysine-39 in the mechanism of the MutT pyrophosphohydrolase. Biochemistry (2000) 1.03
Proton transfer in the mechanism of triosephosphate isomerase. Biochemistry (1998) 1.02
Magnetic resonance and kinetic studies of the manganese(II) ion and substrate complexes of the catalytic subunit of adenosine 3',5'-monophosphate dependent protein kinase from bovine heart. Biochemistry (1979) 1.02
Studies of the catalytic mechanism of an active-site mutant (Y14F) of delta 5-3-ketosteroid isomerase by kinetic deuterium isotope effects. Biochemistry (1991) 1.02
Studies of adenosine triphosphate transphosphorylases. XIV. Equilibrium binding properties of the crystalline rabbit and calf muscle ATP--AMP transphosphorylase (adenylate kinase) and derived peptide fragments. Arch Biochem Biophys (1979) 1.02
Positioning of a spin-labeled substrate analogue into the structure of delta 5-3-ketosteroid isomerase by combined kinetic, magnetic resonance, and X-ray diffraction methods. Biochemistry (1987) 1.02
The enzymatic carboxylation of phosphoenolpyruvate. IV. The binding of manganese and substrates by phosphoenolpyruvate carbosy-kinase and phosphoenolypyruvate carboxylase. J Biol Chem (1968) 1.02
Studies on adenosine triphosphate transphosphorylases. XI. Isolation of the crystalline adenosine triphosphate-creatine transphosphorylases from the muscle and brain of man, calf, and rabbit; and a preparation of their enzymatically active hybrids. Arch Biochem Biophys (1972) 1.01
Dual divalent cation requirement of the MutT dGTPase. Kinetic and magnetic resonance studies of the metal and substrate complexes. J Biol Chem (1994) 1.01
Kinetic, stereochemical, and structural effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase. Biochemistry (1999) 1.01
Nuclear Overhauser effect studies of the conformations and binding site environments of deoxynucleoside triphosphate substrates bound to DNA polymerase I and its large fragment. Biochemistry (1985) 1.01
Pyruvate carboxylase. VII. A possible role for tightly bound manganese. J Biol Chem (1966) 1.00
Solution structure of the quaternary MutT-M2+-AMPCPP-M2+ complex and mechanism of its pyrophosphohydrolase action. Biochemistry (1997) 0.99
Arrangement and conformations of substrates at the active site of pyruvate kinase from model building studies based on magnetic resonance data. J Biol Chem (1976) 0.99
Ultraviolet spectroscopic evidence for decreased motion of the active site tyrosine residue of delta 5-3-ketosteroid isomerase by steroid binding. Biochemistry (1995) 0.99
Magnetic resonance studies of the anomeric distribution and manganese binding properties of fructose phosphates. Biochem Biophys Res Commun (1972) 0.98
Magnetic resonance measurements of intersubstrate distances at the active site of protein kinase using substitution-inert cobalt(III) and chromium(III) complexes of adenosine 5'-(beta, gamma-methylenetriphosphate). Biochemistry (1980) 0.98
Electron and nuclear magnetic resonance studies of the interaction of pyruvate with transcarboxylase. Biochemistry (1974) 0.97
Effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase on the pKa values of active site residues and on the pH dependence of catalysis. Biochemistry (1999) 0.97
Computer simulation studies of mammalian pyruvate kinase. J Biol Chem (1967) 0.97
Magnetic resonance studies of the conformation of enzyme-bound adenylyl(3' leads to 5')uridine and adenosine 5'-triphosphate on RNA polymerase from Esherichia coli. Biochemistry (1977) 0.97
Electron spin resonance studies with dioldehydrase. Evidence for radical intermediates in reactions catalyzed by coenzyme B 12. J Biol Chem (1973) 0.97
Stereochemistry of the concerted enolization catalyzed by delta 5-3-ketosteroid isomerase. Biochemistry (1991) 0.97
Role of magnesium and other divalent cations in ATP-utilizing enzymes. Magnesium (1987) 0.97
The structural basis for the perturbed pKa of the catalytic base in 4-oxalocrotonate tautomerase: kinetic and structural effects of mutations of Phe-50. Biochemistry (2001) 0.97
NMR studies of the backbone protons and secondary structure of pentapeptide and heptapeptide substrates bound to bovine heart protein kinase. Biochemistry (1984) 0.96
Nuclear relaxation and kinetic studies of the role of Mn 2+ in the mechanism of enolase. Biochemistry (1973) 0.96
Concepts and progress in the development of peptide mimetics. J Med Chem (1993) 0.96
Magnetic resonance studies of the role of the divalent cation in the mechanism of yeast aldolase. Biochemistry (1971) 0.95
Mechanism of enzyme action. Annu Rev Biochem (1974) 0.95
Mechanistic studies of cAMP-dependent protein kinase action. CRC Crit Rev Biochem (1984) 0.95
13C NMR relaxation studies of backbone and side chain motion of the catalytic tyrosine residue in free and steroid-bound delta 5-3-ketosteroid isomerase. Biochemistry (1996) 0.95
Fluorocitrate inhibition of aconitase: relative configuration of inhibitory isomer by x-ray crystallography. Science (1970) 0.94
Magnetic resonance and kinetic studies of initiator-substrate distances on RNA polymerase from Escherichia coli. Biochemistry (1978) 0.94
Pyruvate carboxylase. X. The demonstration of direct coordination of pyruvate and alpha-ketobutyrate by the bound manganese and the formation of enzyme-metal-substrate bridge complexes. Biochemistry (1967) 0.94
Magnetic resonance studies of the proximity and spatial arrangement of propionyl coenzyme A and pyruvate on a biotin-metalloenzyme, transcarboxylase. Biochemistry (1976) 0.94
Substrate polarization by residues in delta 5-3-ketosteroid isomerase probed by site-directed mutagenesis and UV resonance Raman spectroscopy. Protein Sci (1992) 0.94
Nuclear magnetic resonance studies of the conformation and kinetics of the peptide-substrate at the active site of bovine heart protein kinase. Biochemistry (1981) 0.94
Role of peripheral side chains of vitamin B12 coenzymes in the reaction catalyzed by dioldehydrase. Biochemistry (1979) 0.93
Chromium(III)-adenosine triphosphate as a paramagnetic probe to determine intersubstrate distances on pyruvate kinase. Detection of an active enzyme-metal-ATP-metal complex. J Biol Chem (1976) 0.93
Magnetic resonance studies of the effect of the regulatory subunit on metal and substrate binding to the catalytic subunit of bovine heart protein kinase. J Biol Chem (1980) 0.93
Metal binding to DNA polymerase I, its large fragment, and two 3',5'-exonuclease mutants of the large fragment. J Biol Chem (1990) 0.93
Short, strong hydrogen bonds at the active site of human acetylcholinesterase: proton NMR studies. Biochemistry (2001) 0.93
Studies on adenosine triphosphate transphophorylases. V. Studies on the polypeptide chains of the crystalline adenosine triphosphate-creatine transphosphorylase from rabbit skeletal muscle. Biochemistry (1967) 0.93
NMR studies of the mechanism of enzyme action. Adv Enzymol Relat Areas Mol Biol (1987) 0.93
Nuclear magnetic resonance studies of the nucleotide binding sites of porcine adenylate kinase. Biochemistry (1982) 0.92
Nucleoside triphosphate-nucleoside diphosphate transphosphorylase (nucleoside diphosphokinase). 3. Subunit structure of the crystalline enzyme from brewers' yeast. J Biol Chem (1973) 0.92
Electron spin echo modulation and nuclear relaxation studies of staphylococcal nuclease and its metal-coordinating mutants. Biochemistry (1988) 0.92