Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma.

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Published in Cancer Med on August 10, 2017

Authors

Vasilios Liapis1, Aneta Zysk1, Mark DeNichilo2, Irene Zinonos1, Shelley Hay1, Vasilios Panagopoulos1, Alexandra Shoubridge1, Christopher Difelice1, Vladimir Ponomarev3, Wendy Ingman4,5, Gerald J Atkins6, David M Findlay6, Andrew C W Zannettino7, Andreas Evdokiou1

Author Affiliations

1: Discipline of Surgery, Breast Cancer Research Unit, Basil Hetzel Institute and Centre for Personalised Cancer Medicine, University of Adelaide, Woodville, South Australia, Australia.
2: Vascular Biology and Cell Trafficking Laboratory, Centre for Cancer Biology, University of South Australia, Adelaide, South Australia, Australia.
3: Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York.
4: Discipline of Surgery, School of Medicine at The Queen Elizabeth Hospital, University of Adelaide, Woodville, Australia.
5: Robinson Research Institute, University of Adelaide, Adelaide, Australia.
6: Discipline of Orthopaedics and Trauma, University of Adelaide, Adelaide, South Australia, Australia.
7: School of Medical Sciences, Myeloma Research Laboratory Cancer Theme, South Australian Health and Medical Research Institute (SAHMRI), Faculty of Health Science, University of Adelaide, Adelaide, Australia.

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